• 제목/요약/키워드: Analysis formula

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동위원소희석 액체크로마토그래피 질량분석법에 의한 분유 내 콜레스테롤의 정량 (Quantitative analysis of cholesterol in infant formula by isotope dilution liquid chromatography-tandem mass spectrometry)

  • 안은정;이화심;김병주;이계호
    • 분석과학
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    • 제28권6호
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    • pp.460-466
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    • 2015
  • 분유 내 콜레스테롤을 정량분석하기 위한 일차분석법으로 동위원소희석 질량분석법을 개발하였다. 내부표준물질로 콜레스테롤-d4를 사용하여 분유에 첨가하였다. 분유에 지방산과 에스테르형태로 결합되어 있는 콜레스테롤을 자유 콜레스테롤로 바꾸어주기 위해 비누화과정을 수행하였다. 비누화과정은 반응온도, 반응시간, 사용한 KOH의 농도에 따라서 최적화하였으며, 그 결과로 분유시료 0.1 g에 대해 70 ℃에서 180 분 동안 8 M의 KOH 0.8 mL를 첨가하여 반응을 진행시키는 최적화조건을 확립하였다. 이와 같은 조건으로 실험을 진행하여 재현성은 0.23%, 확장불확도는 95%의 신뢰범위에서 1.9%로 추정되었다. 확립된 동위원소희석 질량분석법의 유효화를 위해 분유내에서 콜레스테롤의 인증값을 가지는 NIST SRM을 측정하였고 이 결과가 인증값과 불확도 범위내에서 일치하는 것을 확인하였다.

Bioelectrical Impedance Analysis를 통한 건강한 성인과 TPN환자의 기초대사량 산출 (Assessment of Basal Energy Expenditure in Normal Healthy Volunteers and Patients Receiving TPN by Bioelectrical Impedance Analysis)

  • 손은선;김충배;서옥경;신현택;이숙향
    • 한국임상약학회지
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    • 제9권1호
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    • pp.19-26
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    • 1999
  • Adequate nutrition is important in maintaining optimal health. Malnutrition can expose individual to increased risks of morbidity and mortality. The purposes of this study were to determine the basal energy expenditure (BEE) of Korean healthy subjects and TPN patients using Bioelectrical Impedance Analysis (BIA) method and to compare these values with those predicted by Harris-Benedict equation (H-B). BEE values measured by BIA were compared with predicted BEE values by the H-B formula in 59 clinically stable TPN patients and 65 healthy volunteers. In healthy volunteers and TPN patients, statistically significant differences were not shown between the BEE values measured by BIA (1392.5 Kcal and 1325.9 Kcal) and those predicted by H-B formula (1384.1 Kcal and 1270.1 Kcal). In male volunteers, statistically significant differences were not shown between BEE values measured by BIA (1670.7 Kcal) and the H-B formula (1550.9 Kcal), but in female volunteers, statistically significant differences were shown between BEE values measured by BIA (1194.8 Kcal) and the H-B formula (1265.6 Kcal). In male TPN patients, statistically significant differences were shown between BEE values measured by BIA (1453.5 Kcal) and the H-B formula (1335.9 Kcal), but in female TPN patients, statistically significant differences were not shown between BEE values measured by BIA (1126.4 Kcal) and the H-B formula (1167.2 Kcal). In normal healthy volunteers, $90.8\%$ of BEE values measured by BIA and in TPN patients $89.8\%$ of BEE values measured by BIA were within $15\%$ of BEE values predicted by the H-B formula in non-obese subjects. In conclusion, BEE values predicted by H-B formula or measured by BIA can be applied to non-obese Koreans. However, these values should be confirmed with Indirect calorimetry for Koreans.

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통계해석에 의한 G/T 4톤급 연안어선의 유효마력 추정 (Prediction of Effective Horsepower for G/T 4 ton Class Coast Fishing Boat Using Statistical Analysis)

  • 박충환;심상목;조효제
    • 한국해양공학회지
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    • 제23권6호
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    • pp.71-76
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    • 2009
  • This paper describes a statistical analysis method for predicting a coast fishing boat's effective horsepower. The EHP estimation method for small coast fishing boats was developed, based on a statistical regression analysis of model test results in a circulating water channel. The statistical regression formula of a fishing boat's effective horsepower is determined from the regression analysis of the resistance test results for 15 actual coast fishing boats. This method was applied to the effective horsepower prediction of a G/T 4 ton class coast fishing boat. From the estimation of the effective horsepower using this regression formula and the experimental model test of the G/T 4 ton class coast fishing boat, the estimation accuracy was verified under 10 percent of the design speed. However, the effective horsepower prediction method for coast fishing boats using the regression formula will be used at the initial design and hull-form development stage.

지진시 속도의 PSI를 활용한 케이슨식 안벽의 침하량 평가 (Settlement Evaluation of Caisson-Type Quay Wall Using PSI of Velocity During Earthquake)

  • 강기천;어현준;백민제;윤현수;최정욱;윤성규
    • 한국지반신소재학회논문집
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    • 제22권2호
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    • pp.71-83
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    • 2023
  • 해안구조물의 기능 유지를 위해서 침하량을 예측하는 것은 매우 중요하다. 이를 위한 방법으로는 유한요소해석법이나 실물 및 모형실험 등을 들 수 있지만, 이는 비용과 시간이 많이 소요된다는 단점을 가지고 있다. 따라서 본 연구는 케이슨식 안벽구조물의 침하량을 간편하게 예측할 수 있는 간편식 제안을 목적으로 연구가 진행되었다. 연구 진행 과정은 속도의 PSI(Power Spectrum Intensity)를 산정 후, 기존 중력식 방파제의 간편식에 대입하여 구조물의 침하량을 구한다. 이를 수치해석을 통해 얻은 구조물의 침하량과 비교 분석하여 기존 간편식 침하량과 수치해석 침하량 간의 오차가 다소 큰 것을 확인하였고, 이는 기존 간편식의 경우 배후지반에 대해 고려할 수 없었기 때문임을 확인하였다. 따라서 본 연구는 안벽구조물의 배후지반에 대한 보정계수를 제안함으로써 케이슨식 안벽구조물의 침하량을 구할 수 있는 간편식을 나타내었다. 수치해석 침하량과 비교하였을 때, 이 간편식은 케이슨식 안벽 침하량을 산정하는데에 충분한 정밀도를 가지고 있다고 판단하였다. 또한 시간과 비용이 부족한 상황에서 내진성에 취약한 시설을 간편하게 추출할 수 있으며, 스크리닝 기법으로 활용될 수 있을 것으로 기대된다.

IGM에 근입된 말뚝의 지지력 해석을 위한 기준침하량 결정방법 제안 (The Analysis of Shaft Deformation for Evaluating the Bearing Capacity of IGM Sosketed Drilled Shaft)

  • 천병식;김원철;서덕동
    • 한국지반환경공학회 논문집
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    • 제5권3호
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    • pp.17-30
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    • 2004
  • 본 연구에서는 현장타설말뚝의 지지력에 관한 기존 및 IGM 이론의 적용성을 비교 평가하고, 변위를 고려한 지지력의 결정을 위해 IGM 상단부에서의 기준침하량 결정식을 제안하였다. 제안식은 말뚝의 두부침하량, IGM 상부 토층의 하중전이특성 및 말뚝의 탄성압축 이론에 기초하였다. 특히, 기존 및 IGM 이론의 적용성과 제안식의 적용성을 검증하기 위해 국내외 재하시험 결과를 이용한 분석이 실시되었다. 재하시험 결과를 이용하여 분석한 결과 제안식이 활용된 IGM 이론에 의해 향후 말뚝 설계시 변위를 고려한 지지력의 해석이 가능할 것으로 판단되었다. 특히, 제안식에 도입된 침하보정계수 $k_m$은 지반상태나 하중전이 특성을 반영하는 계수로서 하중 및 변형 증가에 따라 변화하는 특징을 보였다.

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교태환(交泰丸)에 대한 심신부교(心腎不交)의 병기(病機)분석과 그 조성약물의 배오(配伍)분석 (Pathological Analysis on Disharmony between the Heart and the Kidney for the Gyotae-hwan Formula and Compatibility Analysis on its Composition)

  • 이석희;노종성;신순식
    • 대한한의학원전학회지
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    • 제35권3호
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    • pp.21-31
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    • 2022
  • Objectives : The Gyotae-hwan formula has traditionally been applied to conditions of fearful throbbing[怔忡] and insomnia due to disharmony of the Heart and Kidney, of which experimental and clinical research has been carried out while those on its pathological mechanism and constituent compatibility have been inadequate. Methods : Pathological mechanism and constituent compatibility of the Gyotae-hwan formula as listed in the 『Comprehensive Medicine According to Master Han』(韓氏醫通) and the『Simple Recipes for Four Disciplines』(四科簡效方) were analyzed. Findings from recent researches searched using the keywords '交泰丸' and '교태환' in the OASIS and CNKI databases were referenced as well. Results : The Gyo-tae hwan was first mentioned in the text 『Comprehensive Medicine According to Master Han』by Mao Han in terms of constituent medicinals and application while measurements and name of formula were not listed while the concept of harmony between the Heart and Kidney was mentioned. In the『Simple Recipes for Four Discipline s』 written by Shixiong Wang, measurements of constituent medicinals, usages and name of formula were finally mentioned, along with its efficacy to treat fearful throbbing and insomnia due to disharmony between the Heart and the Kidney. Conclusions : In conclusion, the Gyo-tae hwan uses Coptidis Rhizoma as chief herb and Cinnamomi Cortex as assistant herb to change the state of disharmony between the Heart and Kidney to a harmonious state, treating insomnia and fearful throbbing.

지표화 산불의 화염전파 수치해석 (A Numerical Study of Flame Spread of A Surface Forest Fire)

  • 김동현;이명보;김광일
    • 한국전산유체공학회:학술대회논문집
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    • 한국전산유체공학회 2008년도 춘계학술대회논문집
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    • pp.80-83
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    • 2008
  • The characteristics of the spread of a forest fire are generally related to the attributes of combustibles, geographical features, and meteorological conditions, such as wind conditions. The most common methodology used to create a prediction model for the spread of forest fires, based on the numerical analysis of the development stages of a forest fire, is an analysis of heat energy transmission by the stage of heat transmission. When a forest fire breaks out, the analysis of the transmission velocity of heat energy is quantifiable by the spread velocity of flame movement through a physical and chemical analysis at every stage of the fire development from flame production and heat transmission to its termination. In this study, the formula used for the 1-dimensional surface forest fire behavior prediction model, derived from a numerical analysis of the surface flame spread rate of solid combustibles, is introduced. The formula for the 1-dimensional surface forest fire behavior prediction model is the estimated equation of the flame spread velocity, depending on the condition of wind velocity on the ground. Experimental and theoretical equations on flame duration, flame height, flame temperature, ignition temperature of surface fuels, etc., has been applied to the device of this formula. As a result of a comparison between the ROS(rate of spread) from this formula and ROSs from various equations of other models or experimental values, a trend suggesting an increasing curved line of the exponent function under 3m/s or less wind velocity condition was identified. As a result of a comparison between experimental values and numerically analyzed values for fallen pine tree leaves, the flame spread velocity reveals has a error of less than 20%.

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신체부위별 측정변인에 따른 경신강지환16의 비만 개선효과 평가 (Clinical efficacy of Gyeongshingangjeehwan16 according to obeisty related to measurement variables.)

  • 정양삼;윤기현;최승배;윤미정;신순식
    • 대한한의학방제학회지
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    • 제16권1호
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    • pp.169-183
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    • 2008
  • In this study, we measured body mass index, visceral fat ratio and 6 parts of body, neck circumference, circumference of upper arm, chest circumference, abdomen circumference, hip circumference, and thigh circumference by bioimpedence analysis system, after taking Gyeongshingangjeehwan16 (GGEx16) in five months except the first period before taking GGEx16 on 49 women who are obesity or high-level obesity. In order to examine the significance test for the effect of obesity improvement of GGEx16, we practices repeated measure ANOVA with values of measurement variables in 6 monthly times. As a result of all measurement variables, there were significant difference (P-value=0.001). Therefore, we can say that GGEx16 is effective about obesity improvement. As it dramatically decreased between second measure period and first measure period for all measure variables, we can see that there were the most effect of GGEx16 in the first time after taking GGEx16. It is known that a important measurement variable to have a effect for obesity improvement about two variable which are body mass index and visceral fat ratio is waist circumference through correlation analysis. The result of whether there are differences to effect of obesity improvement for GGEx16 around the climacteric, there were significant difference for the effect of obesity improvement for GGEx16 around the climacteric about all parts of body (P-value=0.001). There were also powerfully difference in effect of obesity improvement for GGEx16 around the climacteric about all parts of body (P-value=0.001). Especially, the climacteric before is more effective than the climacteric after in the aspect of the effect of GGEx16.

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플랜지형 벽체 효과를 고려한 철근 콘크리트 전단벽 구조물의 고유주기식 (Natural Period Formula of a Reinforced Concrete Shear Wall Structure Considering Flange Wall Effect)

  • 노지은;김중호;허무원;박태원;이상현
    • 한국지진공학회논문집
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    • 제22권2호
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    • pp.55-62
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    • 2018
  • In this study, natural period formular is presented for a RC shear wall structure with H-, T-, and L-shaped wall sections. The natural period formular proposed by Goel and Chopra and adopted in ASCE 7-10 was modified by using the ratio of the flange and web wall area. The natural periods of structures with H-shaped wall were numerically obtained, the results indicated that the ASCE 7-10 could not consider the natural period variation according to the length of the flange wall, but the proposed formula could do. Especially, ASCE 7-10 estimated much longer periods than eigenvalue analysis, and this implies that conservative seismic design is difficult. The periods by eigenvalue analysis exist between the upper and lower bounds given by the proposed formula, and conservative design is possible by using the proposed lower bound value. In order to verity the effectiveness of the proposed method, actual residential buildings with various types of flange walls are considered. Ambient vibration tests, eigenvalue analyses, and nonlinear dynamic analyses were conducted and the periods were compared with the values by ASCE 7-10 and the proposed formula. The results showed that the proposed formula could estimate more accurately the periods than ASCE 7-10.

정전력 구동기의 동특성 해석 (A Study on Dynamic Analysis of the Electrostatic Actuator)

  • 이상규;김지남;문원규;최진환;박일한
    • 한국정밀공학회:학술대회논문집
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    • 한국정밀공학회 2005년도 춘계학술대회 논문집
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    • pp.686-689
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    • 2005
  • A numerical simulation method is developed to analyze the dynamic response of a cantilever switch, which is driven by electrostatic force and a basic component of electro-mechanical coupled system. First, point-charges model on conductor is proposed as a lumped parameter of electrical part. Then, this model is easily incorporated into a multi-body dynamics analysis algorithm, the generalized recursive dynamics formula previously developed by our research group. The resulting motion of a coupled overall system is formulated as a differential algebraic equation form including electrical and mechanical variables together. The equation is simultaneously solved in every time step. To implement this approach into the useful dynamics analysis tool, we used multibody dynamics software (RecurDyn) based on the generalized recursive formula using relative coordinate. The developed numerical simulation tool is evaluated by applying to many different driving condition and switch configuration. The final analysis model will be added to RecurDyn as a basic module for dynamics analysis of electro-mechanical coupled system.

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