• 한국임상수의학회지
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• 제40권2호
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• pp.147-151
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• 2023

A 6-year-old female Chihuahua was presented to the Animal Medical Center for surgical resection of a perineal mass that had recently increased in size. Ultrasonography revealed a large, homogeneous fatty mass with irregular margins between the surrounding muscle layers due to infiltrating fatty tissues. Cytological findings from fine-needle aspirates revealed numerous sheets and clusters of adipocytes, which was consistent with the fatty mass. Based on ultrasonographic and cytological findings, an infiltrative lipoma was suspected. During the surgery, the perineal mass was found to be non-encapsulated, irregularly marginated, and extensively distributed into the surrounding muscles. The mass extended inside the pelvic cavity and left anal sac. The perineal mass was surgically removed and submitted for histopathologic examination. Histopathology confirmed that the mass was an infiltrative lipoma invading into the anal sac and surrounding muscles. The present report was an unusual presentation of infiltrative lipoma that invaded the anal sac in the perineum.

• 한국임상수의학회지
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• 제24권1호
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• pp.35-37
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• 2007

개의 오른쪽 또는 왼쪽 항문낭에 화농성 삼출물이 있거나 항문낭이 개방된 8마리의 개를 대상으로 항문낭 적출술을 하였다. 환자의 체중은 3-8 kg이며. 항문낭을 쉽게 절제하기 위하여 폴리카테터(1.5 ml, 6호)를 이용하여 폐쇄법으로 항문 적출술을 하였다. 항문낭 적출술을 하는 동안 모든 환자에서 폴리카테터를 팽창하여 항문낭을 쉽게 식별할 수 있었다. 항문낭 적출술을 실시 한 환자들을 대상으로 1-3개월 동안 임상증상을 추적하였다. 항문낭 적출술이 만성 항문낭염 또는 항문 질환에 좋은 치료법이었다. 폴리카테터의 이용은 항문낭의 적출 시 항문낭을 쉽게 구별할 수 있었고 경제적이었다.

• 대한수의학회지
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• 제35권2호
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• pp.353-360
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• 1995

Gross and light microscopic findings are described for 34 canine sweat gland neoplasms including tumors derived from apocrine gland in anal sac and ceruminous gland in ear. Affected dogs are usually 5.2 years and sex predilection have not been seen. Sweat gland carcinoma(n=19) is predominant type for sweat gland neoplsm, while papillary syringadenoma(n=2) and spiradenoma(n=2) are rare type in this study. Distinct patterns identified in cutaneous sweat gland carcinoma are tubular(n=7), solid(n=5), mixed(n=4), papillary(n=2) and signet-ring(n=1). Mixed tumors which are characterized by myxomatous and chondroid metaplasia are seen in cutaneous sweat and ceruminous gland. The carcinoma derived apocrine gland of the anal sac induces humoral hypercalcemia of malignancy in two dogs in this study. Histologically, apocrine gland carcinoma of the anal sac has distinct rossette formation.

• 한국임상수의학회지
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• 제36권6호
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• pp.349-352
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• 2019

A five-year-old female Yorkshire Terrier dog presented with a perianal mass. Fine needle aspiration revealed that the mass comprised two different types of cells: hepatoid epithelial cells and melanin-containing melanocytes. Histopathological examination confirmed perianal gland adenoma with malignant melanoma. Evidence of metastasis was found on thoracic radiography with soft-tissue densities observed within the pulmonary parenchyma. The dog survived for three months after diagnosis of malignant melanoma. This report describes the clinical findings, diagnostics used, cytological and histopathological findings, and the potential prognosis for a dog diagnosed with malignant anal sac melanoma.

• Journal of Korean Neurosurgical Society
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• 제42권1호
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• pp.46-48
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• 2007

Distant metastasis of squamous cell carcinoma from the anal canal is an uncommon event. However, hematogenous spread to the vertebrae may occur in the course of this disease. The route of metastasis from the anal canal seems to be Batson's vertebral venous system. A 52-year-old female patient presented with lower back and right leg pain of one-week history. She has undergone radiotherapy and chemotherapy for squamous cell carcinoma of the anal canal and then was followed by surgical resection. Three months later, magnetic resonance images of the lumbar spine disclosed a well-enhanced mass of L5 vertebral body compressing the thecal sac. Surgical decompression and biopsy were performed. Histopathological study confirmed carcinoma of the squamous cell origin. We report a ra re case of vertebral metastasis from squamous cell carcinoma of the anal canal with a pertinent review of literature.

• 한국임상수의학회지
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• 제26권6호
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• pp.606-611
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• 2009

2006-2008년에 5마리의 환자가 아포크린샘암종으로 진단받았다. 품종은 다양하였으며 진단 당시 평균 연령은 11세이었다. 이들 중 3마리에서 종양으로 인한 고칼슘혈증이 발생하였으며, 한 마리는 화학요법(chemotherapy) 받지 않고 진단 1달 후 사망하였다. 나머지 네 마리의 환자들은 항암제 투여, 수술 등의 방법으로 치료를 받았으며 수술과 화학요법을 병행한 환자는 치료 종료 후 9개월째 완전완화(complete remission) 상태를 유지하고 있다. 화학요법만 받은 3마리의 환자들은 질병지속(stable disease) 상태로 유지되고 있으며 이 중 한 마리는 진단 후 2개월째에 사망하였다. 따라서 개의 아포크린샘암종의 치료법으로 수술 및 방사선 치료를 적용할 수 없는 경우에, 항종양제 단독 투여는 보조적으로 효과가 있는 것으로 사료된다.

• 한국임상수의학회:학술대회논문집
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• 한국임상수의학회 2006년도 추계학술대회 및 정기총회
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• pp.133-133
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• 2006

• 한국임상수의학회지
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• 제34권4호
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• pp.272-274
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• 2017

A 1-year-old intact male Cavalier King Charles Spaniel was presented with a ruptured anal sac. On routine preanesthetic screening tests for surgical resection, the thrombocytopenia was observed by an impedance-type autoanalyzer. A peripheral blood smear was used as a follow-up test and giant platelets were seen on the smear. DNA assay of this patient confirmed that the cause of the platelet abnormalities in this patient was genetic mutation. To our knowledge, this is the first case report of macrothrombocytopenia confirmed based on the DNA assay results, in a Cavalier King Charles Spaniel in Korea.

• Journal of Veterinary Science
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• 제24권6호
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• pp.76.1-76.6
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• 2023

An 11-year-old neutered male Miniature Poodle with a stage 3 apocrine gland adenocarcinoma was started on chemotherapy with toceranib phosphate after surgery. Beginning on day 10 of toceranib, the dog's foot pads became erythematous and hyperkeratinized. The dog complained of pain, inability to walk, depression, and loss of appetite. The symptoms resolved when toceranib was discontinued and reappeared when toceranib was resumed. Grade 3 palmar-plantar erythrodysesthesia was identified as an adverse event of toceranib based on the VCOG-CTCAE and Naranjo scale. Although very rare in veterinary medicine, clinicians should consider that palmar-plantar erythrodysesthesia can occur after toceranib administration.

• 한국수산과학회지
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• 제38권5호
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• pp.298-303
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• 2005

This study described the reproductive behavior and the morphological development of the larvae and juvenile of the hedgehog seahorse (Hippocampus spinosissimus). Larvae released from male seahorse were reared for 30 days in the laboratory. At the birth, the small flap-like mouth and anus of the yolk-sac larvae were open, and the yolk was completely absorbed within 1 day. The size of newborn larvae ranged 7.01-13.19mm (mean $9.26\pm1.9mm$, n=9) in TL (total length). The larvae had 15-16 pectoral fin rays and 19 dorsal fin rays, but 4 anal fin rays were not completely developed. The larval size ranged 13.38-14.38 mm (mean $13.96\pm0.3mm$, n=6) in TL at 1 day after release, and they had 17 pectoral fin rays, 20 dorsal fin rays and 4 anal fin rays when the larvae reached the juvenile stage. Juvenile size ranged 14.98-16.42mm (mean $15.84\pm0.5mm$, n=5) in TL at 3 days after release, and 1, 4, 6, 8 trunk spines extended quickly. Terminal part of the coronet became a four-forked wedge shape concurrently. Juvenile became 23.25mm (n=l) in TL after 15 days and all 11 trunk rings was connected completely. After 20 days, the juveniles were 24.66-28.65mm (mean $27.26\pm1.6mm$, n=5) in TL, and many melanophores appeared in integument. In the eye lenses, 5-6 lusters were formed. After 30 days, the juveniles were 26.78-28.26 mm (mean $27.36\pm0mm$, n=4)in TL and 8-9 lusters appeared on the eye lenses. Coronet terminal part developed to a five-forked crown-shape completely.