• International Journal of Oral Biology
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• 제41권1호
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• pp.33-38
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• 2016

One of functions of Galla Rhois (GR) is reportedly an anti-inflammatory effect on the several inflammatory diseases. However, an effect of GR related to periodontitis has not been investigated. In the present study, we examined the effect of the hexane extract of Galla Rhois (GR-H) on periodontitis. Cytotoxicity was assessed by MTS analysis using human gingival fibroblast (hGF) cells. Experimental periodontitis was induced by injecting E.coli LPS into the palatal gingiva maxillary molar thrice weekly for 3 weeks (LPS group). GR-H diluted in 1xPBS was orally administrated using a syringe at 30 mg/kg body weight and 100 mg/kg body weight once a day (GR-H group). GR-H effect on the alveolar bone loss (ABL) was digitized with a micro-CT. GR-H treatment at concentrations exceeding 0.5 mg/ml showed cytotoxic effect in hGF cells. The micro-CT among groups were presented for the different distances from cemento-enamel junction (CEJ) to alveolar bone crest (ABC). The results indicated an inhibitory effect on alveolar bone loss for orally administered GR-H in a model of LPS-induced periodontitis.

• Restorative Dentistry and Endodontics
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• 제41권1호
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• pp.63-67
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• 2016

During clinical endodontic treatment, we often find radiopaque filling material beyond the root apex. Accidental extrusion of calcium hydroxide could cause the injury of inferior alveolar nerve, such as paresthesia or continuous inflammatory response. This case report presents the extrusion of calcium hydroxide and treatment procedures including surgical intervention. A 48 yr old female patient experienced Calcipex II extrusion in to the inferior alveolar canal on left mandibular area during endodontic treatment. After completion of endodontic treatment on left mandibular first molar, surgical intervention was planned under general anesthesia. After cortical bone osteotomy and debridement, neuroma resection and neurorrhaphy was performed, and prognosis was observed. But no improvement in sensory nerve was seen following surgical intervention after 20 mon. A clinician should be aware of extrusion of intracanal medicaments and the possibility of damage on inferior alveolar canal. Injectable type of calcium hydroxide should be applied with care for preventing nerve injury. The alternative delivery method such as lentulo spiral was suggested on the posterior mandibular molar.

• 대한치과마취과학회지
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• 제7권2호
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• pp.131-134
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• 2007

Inferior alveolar nerve block anesthesia is one of the most common procedures in dental clinic. Although it is well known as safe procedure, complications always can be occurred. Ocular complications such as diplopia, loss of vision, opthalmoplegia are very rare, but once it happens, dentist and patient can be embarrassed and rapport will be decreased between them. We experienced one diplopia case after inferior alveolar nerve block anesthesia and treated without any further complication. We report this case and describe the cause, diagnosis, and treatment objectives of diplopia caused by inferior alveolar nerve block anesthesia.

• 대한치과의사협회지
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• 제53권8호
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• pp.545-557
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• 2015

The modified ridge splitting/expansion technique combined with guided bone regeneration (GBR) for implant surgery is used to expand the narrow and atrophied edentulous alveolar ridge. Also, the simultaneous implant placement after ridge splitting/expansion technique can reduce the treatment and healing time. This case report includes three patients with a narrow edentulous alveolar ridge of the 2 to 4mm. All three patients underwent a fracture of thin buccal cortical bone plate, and these defects were corrected by the use of the guided bone regeneration (GBR). After 7 to 18 months, all surgical area was stable, and all implant showed a good healing state on the clinical and radiographic examination. In conclusion, though this surgical method is technique sensitive, the modified ridge splitting/expansion technique combined with GBR for implant surgery is recommended for a horizontal augmentation in the narrow edentulous alveolar ridge.

• 말소리와 음성과학
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• 제7권3호
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• pp.117-128
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• 2015

This paper investigates the acoustic-perceptual relation between Korean dent-alveolar fricatives and the English voiceless alveolar fricative /s/ in varied prosodic contexts (e.g., stress, accent, and word initial position). The denti-alveolar fricatives in Korean show a two-way distinction, which can be referred to as either plain (lenis) /s/ or fortis /$s^*$/. The English alveolar voiceless fricative /s/ that corresponds to the two Korean fricatives would be placed in a one-to-two non-native phoneme mapping situation when Korean listeners hear English /s/. This raises an interesting question of how the single fricative of English perceptually maps into the two-way distinction in Korean. This paper reports the acoustic-perceptual mapping pattern by investigating spectral properties of the English stimuli that are heard as either /s/ or /$s^*$/ by Korean listeners, in order to answer the two questions: first, how prosody influences fricatives acoustically, and second, how the resultant properties drive non-native listeners to interpret them as segmental features instead of as prosodic information. The results indicate that Korean listeners' responses change depending on the prosodic context in which the stimuli are placed. It implies that Korean speakers interpret some of the information provided by prosody as segmental one, and that the listeners take advantage of the information in their judgment of non-native phonemes.

• Molecules and Cells
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• 제44권5호
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• pp.292-300
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• 2021

Macrophages residing in various tissue types are unique in terms of their anatomical locations, ontogenies, developmental pathways, gene expression patterns, and immunological functions. Alveolar macrophages (AMs) reside in the alveolar lumen of the lungs and serve as the first line of defense for the respiratory tract. The immunological functions of AMs are implicated in the pathogenesis of various pulmonary diseases such as allergic asthma, chronic obstructive pulmonary disorder (COPD), pulmonary alveolar proteinosis (PAP), viral infection, and bacterial infection. Thus, the molecular mechanisms driving the development and function of AMs have been extensively investigated. In this review article, we discuss the roles of granulocyte-macrophage colony-stimulating factor (GM-CSF) and transforming growth factor (TGF)-β in AM development, and provide an overview of the anti-inflammatory and pro-inflammatory functions of AMs in various contexts. Notably, we examine the relationships between the metabolic status of AMs and their development processes and functions. We hope that this review will provide new information and insight into AM development and function.

• Archives of Plastic Surgery
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• 제50권5호
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• pp.478-487
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• 2023

Background The outcome of alveolar grafting with synthetic bone substitute (Osteon III) in various bone defect volumes is highlighted. Methods A prospective study was accomplished on 55 patients (6-13 years of age) with unilateral alveolar bone cleft. Osteon III, consisting of hydroxyapatite and tricalcium phosphate, is used to reconstruct the defect. Alveolus defect diameter was calculated before surgery (V1), after 3 months (V2), and finally after 6 months (V3) postsurgery. In the t-test, a significant difference and correlation between V1, V2, and V3 are stated. A p-value of 0.01 is considered a significant difference between parameters. Results The degree of cleft is divided into three categories: small (9 cases), medium (20 patients), and large (26 cases).The bone volume of the clefted site is divided into three steps: volume 1: (mean 18.1091 mm³); step 2: after 3 months, volume 2 resembles the amount of unhealed defect (mean 0.5109 mm³); and the final bone volume assessment is made after 6 months (22.5455 mm³). Both show statistically significant differences in bone volume formation. Conclusion An alloplastic bone substitute can also be used as a graft material because of its unlimited bone retrieval. Osteon III can be used to reconstruct the alveolar cleft smoothly and effectively.

• 대한치과의사협회지
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• 제19권3호통권142호
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• pp.279-282
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• 1981

The authors observed the degree of alveolar bone resorption on the intraoral roentgenogram of 105 patients who were affected by periodontal disease, and following results were obtained. That is, the alveolar bone resorption due to the periodontal disease showed increased tendency as aging, and severe degree on the mandible in comparison with the maxilla, and revealed sere destruction on the area of mandibular incisors and maxillary molars.

• Journal of Dental Anesthesia and Pain Medicine
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• 제17권2호
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• pp.129-134
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• 2017

Efforts to apply augmented reality (AR) technology in the medical field include the introduction of AR techniques into dental practice. The present report introduces a simple method of applying AR during an inferior alveolar nerve block, a procedure commonly performed in dental clinics.

• Asian-Australasian Journal of Animal Sciences
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• 제14권1호
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• pp.101-103
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• 2001

Scanning Electron Microscopy of twelve lactating buffalo mammary gland was done. The lactating mammary gland showed alveolus, arrangement of blood vessels and myoepithelial cells on the alveolus, the formation of lobules and interlobular connective tissue. From the exposed alveolar lumen fat globule formation can be seen which is still attached to the alveolar surface by microvilli. This technique should further be extended to study the alveolar structure in detail during different stages of mammary gland development in buffaloes.