• 한국작물학회지
• /
• 제48권
• /
• pp.31-40
• /
• 2003

Phytoestrogens are oestrogenic compounds found in plants and consist of isoflavones, lignans, and coumestans. The structural similarity of phytoestrogens to endogenous oestrogens has promoted the hypothesis that phytoestrogens exert hormonal or anti-hormonal effects relevant to the risk of hormone-dependent disease and/or their suitability as a dietary alternative to hormone replacement therapy. Epidemiological studies suggest that food stuffs containing phytoestrogens may have a beneficial role in protecting against a number of chronic disease and conditions. It is thought that these estrogen-like compounds may protect against chronic diseases, such as hormone-dependent cancers, cardiovascular disease and osteoporosis. Furthermore, phytoestrogens are used as a natural alternative to hormone replacement therapy and to reduce menopausal symptoms. Phytoestrogens are considered good candidates for use in natural therapies and as chemopreventive agents in adults. However safe and efficacious levels have yet to be established.

• Journal of Advanced Marine Engineering and Technology
• /
• 제36권7호
• /
• pp.885-893
• /
• 2012

DME (Dimethyl ether) is regarded as one of the candidates of alternative fuels for diesel engine, because of its higher cetane number suitable for a compression ignition engine. Also, DME is a simple chemical structure, colorless gas that is easily liquefied and transported. On the other hand, Bunker oil (JIS C heavy oil) has long been used as a basic fuel in marine diesel engines and is the lowest grade fuel oil. In this study, the combustion and emission characteristics were measured experimentally in the direct injection type diesel engine operated with DME and Bunker oil mixed fuel. From our experimental results, it is induced that DME and Bunker oil blended fuel would be an effective fuel which can reduces the concentration of harmful matter in exhaust gases.

• Archives of Plastic Surgery
• /
• 제46권5호
• /
• pp.475-479
• /
• 2019

The Goldilocks technique for breast reconstruction utilizes redundant mastectomy flap tissue to construct a breast mound. This technique is suitable for women who decline, or are poor candidates for, traditional postmastectomy reconstruction. Moreover, this technique can be applied in secondary operations after the failure of initial reconstruction efforts. A 74-year-old patient underwent the Goldilocks procedure after reconstruction failure with an implant and acellular dermal matrix. At her 6-month follow-up, the cosmetic outcome of the procedure was satisfactory, and no complications were noted. Therefore, the Goldilocks procedure is a safe alternative to reconstruct breast mounds following reconstruction failure, especially in obese patients.

• 정보처리학회논문지C
• /
• 제19C권3호
• /
• pp.179-184
• /
• 2012

NIST(National Institute of Standards and Technology)는 SHA-2의 대체 알고리즘 부재로 SHA-3 개발 프로젝트를 진행 되고 있는 중 이다. 2010년 최종 라운드 후보 5개가 발표되었고, SHA-3 최종 라운드 5개의 후보에 대한 부채널 공격 시나리오가 제안되었다. 본 논문에서는 SHA-3 최종 라운드 후보 중 Skein에 대한 부채널 공격 시나리오를 32비트 레지스터를 사용하는 ARM Chip을 이용하여, 8 비트의 블록단위로 Divide and Conquer 분석이 가능함을 실험을 통해 증명한다. 9700개의 파형으로 128비트 키의 모든 비트를 찾을 수 있음을 실험으로 검증하였다.

• 설비공학논문집
• /
• 제10권3호
• /
• pp.292-302
• /
• 1998

In this study, 14 refrigerant mixtures composed of R32, R125, R134a, R143a, R152a, and R1270(Propylene) were tested in a breadboard heat pump in an attempt to replace R22 used in most of the residential air conditioners and heat pumps. The heat pump was of 1 ton capacity and water was employed as the secondary heat transfer fluids. All tests were conducted under ARI test A condition. Ternary mixtures composed of R32, R125, and R134a were shown to have 4∼5% higher COP and capacity than R22 and hence they seem to be very promising candidates to replace R22. On the other hand, ternary mixtures containing R125, R134a, and R152a have lower COP and capacity than R22. R32/R134a binary mixtures show a 7% increase in COP and have the similar capacity to that of R22 and hence they are also good candidates to replace R22. Special care must be exercised when a suction line heat exchanger is used with these mixtures in air conditioners. Finally, the compressor discharge temperatures of all mixtures tested were lower than those of R22 by 15.g∼34.7t, which indicates that these mixtures would offer better system reliability and longer life time than R22.

• Clinics in Shoulder and Elbow
• /
• 제22권4호
• /
• pp.227-234
• /
• 2019

Lateral epicondylitis, also known as 'tennis elbow', is a degenerative rather than inflammatory tendinopathy, causing chronic recalcitrant pain in elbow joints. Although most patients with lateral epicondylitis resolve spontaneously or with standard conservative management, few refractory lateral epicondylitis are candidates for alternative non-operative and operative modalities. Other than standard conservative treatments including rest, analgesics, non-steroidal anti-inflammatory medications, orthosis and physical therapies, nonoperative treatments encompass interventional therapies include different types of injections, such as corticosteroid, lidocaine, autologous blood, platelet-rich plasma, and botulinum toxin, which are available for both short-term and long-term outcomes in pain resolution and functional improvement. In addition, newly emerging biologic enhancement products such as bone marrow aspirate concentrate and autologous tenocyte injectates are also under clinical use and investigations. Despite all non-operative therapeutic trials, persistent debilitating pain in patients with lateral epicondylitis for more than 6 months are candidates for surgical treatment, which include open, percutaneous, and arthroscopic approaches. This review addresses the current updates on emerging non-operative injection therapies as well as arthroscopic intervention in lateral epicondylitis.

• 한국방재학회 논문집
• /
• 제9권3호
• /
• pp.117-126
• /
• 2009

유역종합치수계획 수립 시 유역 내 적용이 가능한 구조물적 비구조물적 치수계획은 매우 광범위하고, 특히 그 중에서도 구조물적 홍수방어 시설들의 특성은 매우 다양하다. 이들을 조합하여 유역의 홍수 저감능력을 최대화 하는 최적대안을 선정하는 것은 쉬운 일이 아니며, 현재 구조물적 홍수방어 후보대안에 대한 적절한 평가 기준이나 다양한 홍수방어 후보대안들 중 최적대안의 선정에 관한 지침 또한 미흡한 실정이다. 본 연구에서는 유역종합치수계획의 구조물적 홍수방어 후보대안들에 대한 치수경제성 및 정책성 평가 결과를 바탕으로 최적대안을 선정하는 과정에서, 의사결정기법 중의 하나인 계층화분석기법을 도입하여 적용함으로써 평가항목들 간의 가중치 결정 및 최적대안을 도출하는 과정을 예시하였다. 후보대안들 각각의 하위 세부 평가항목들의 가중치 결정에는 계층화분석기법 전용 프로그램인 Expert Choice 11.5를 활용하였으며, 연구 결과를 바탕으로 유역종합치수계획의 구조물적 홍수방어 최적대안 선정에 있어 보다 표준화된 절차를 제시하였다.

• Journal of Microbiology and Biotechnology
• /
• 제34권8호
• /
• pp.1642-1652
• /
• 2024

Arctium lappa (Burdock) root is used in various culinary applications especially in Asian Cuisine. Arctigenin (ARC) is a polyphenolic compound abundant in the roots of the burdock plant from which it derives its name. The emergence of bacterial resistance is a growing global worry, specifically due to the declining availability of new antibiotics. Screening for the antibacterial candidates among the safe natural products is a promising approach. The present study was aimed to assess the antibacterial activity of ARC against Pseudomonas aeruginosa exploring its effect on the bacterial cell membrane. Furthermore, the anti-virulence activities and anti-quorum sensing (QS) activities of ARC were in vitro, in vivo and in silico assessed against P. aeruginosa. The current results showed the ARC antibacterial activity was owed to its disruption effect of the cell membrane. ARC at sub-MIC significantly decreased the formation of biofilm, motility, production of extracellular enzymes and in vivo protected mice against P. aeruginosa. These anti-virulence activities of ARC are owed to its interference with bacterial QS and its expression. Furthermore, ARC showed mild effect on mammalian erythrocytes, low probability to induce resistance and synergistically combined with antibiotics. In summary, the promising anti-virulence properties of ARC indicate its potential as an effective supplement to conventional antibiotics for treating severe P. aeruginosa infections.

• 국제초고층학회논문집
• /
• 제3권2호
• /
• pp.107-120
• /
• 2014

A Reinforced concrete (RC) shear wall system with coupling beams has been known as one of the most promising structural systems for high-rise buildings. However, significantly large flexural and/or shear stress demands induced in the coupling beams require special reinforcement details to avoid their undesirable brittle failure. In order to solve this problem, one of promising candidates is frictional hysteretic energy dissipating devices (HEDDs) as an alternative to the coupling beams. The introduction of frictional HEDDs into a RC shear wall system increases energy dissipation capacity and maintains the frame action after their yielding. This paper investigates the strength demands (specifically yield strength levels) with a maximum allowable ductility of frictional HEDDs based on comparative non-linear time-history analyses of a prototype RC shear wall system with traditional RC coupling beams and frictional HEDDs. Analysis results show that the RC shear wall systems coupled by frictional HEDDs with more than 50% yield strength of the RC coupling beams present better seismic performance compared to the RC shear wall systems with traditional RC coupling beams. This is due to the increased seismic energy dissipation capacity of the frictional HEDD. Also, it is found from the analysis results that the maximum allowable ductility demand of a frictional HEDD should increase as its yield strength decreases.

• 제어로봇시스템학회:학술대회논문집
• /
• 제어로봇시스템학회 2003년도 ICCAS
• /
• pp.1830-1835
• /
• 2003

A novel index representing burden distribution form in the blast furnace is developed and index estimation model is built with an empirical modeling method to monitor inner condition of the furnace without expensive sensors. To find the best combination of index and modeling method, two candidates for the index and four modeling methods have been examined. Results have shown that 3-D index have more resolution in describing the distribution form than 1-D index and ANN model produces smallest RMSE due to nonlinearity between the indices and charging mode. Although ANN has shown the best prediction accuracy in this study, PLS can be a good alternative due to its advantages in generalization capability, consistency, simplicity and training time. The second best result of PLS in the prediction results supports this fact.