• Title/Summary/Keyword: Alternative application

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염모제 사용에 의한 인체림프구의 DNA 손상 변화 (Effects of Hair Dyeing Application on the DNA Damage in Human Lymphocytes)

  • 김영철;심미자;권정숙
    • Environmental Analysis Health and Toxicology
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    • 제19권1호
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    • pp.101-107
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    • 2004
  • To ascertain the effects of hair dyeing application on the DNA damage in human lymphocytes, a mixture of permanent black colored hair dye with the same amount of oxidant containing 6% hydrogen peroxide was used. A hair dyeing with contacting the scalp (conventional dyeing) and a hair dyeing with 3 to 4mm away from the scalp (alternative dyeing) were applied to each If young healthy women. Blood was taken from the brachial vein at two sampling times, just before and 6 hours after the hair dyeing, and tail extent moment(TEM) and tail length (TL) were measured by using a comet assay. After dyeing, TL was significantly increased in both conventional dyeing group and alternative dyeing group compared with before dyeing as an average of 47% and 28%, respectively, and TL for conventional dyeing group was higher than alternative dyeing group as an average of 1.2 fold. After dyeing, TEM was significantly increased in both conventional dyeing group and alternative dyeing group compared with before dyeing as an average of 192% and 76%, respectively, and TEM for conventional dyeing group was significantly higher than alternative dyeing group as an average of 1.7 fold. Therefore, alternative dyeing application was induced to lower lymphocyte DNA damage than conventional dyeing application, and TEM was appeared to be a more sensitive tool for the measurement of lymphocyte DNA damage than TL in this study.

대체에너지를 이용한 국·내외 가로시설물 개발 유형 분석 (Analysis of Development Situation of Korean and Foreign Street Furnitures Using Alternative Energy)

  • 김자경;박형진
    • KIEAE Journal
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    • 제10권1호
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    • pp.33-44
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    • 2010
  • These days, the use of alternative energy is recognized as one of countermeasures to rising oil prices and climate-change agreements. Especially, it is regarded as a main element to realize 'Low-Carbon Green Growth', one of the key policies of MB government. However, though alternative energy, renewable energy, is a main policy issue of the present administration, there are many problems to solve: the lack of recognition of its energy, the low level of its technology, its expert's shortage, and its limited application fields. Therefore, to stimulate the use of alternative energy in Korea and to change the recognition of this energy, it is needed to utilize it to urban street furniture that many people visit and use. In particular, if alternative energy is first applied to street furniture that needs energy for its management, the effect of publicity and energy saving will be so great. In this study, for the basic research to introduce and promote various alternative energy sources such as solar power, wind power, small hydro power, and human power, we analyzed the present condition of development of Korean and foreign street furniture items. Furthermore, we evaluated the level of development of these street furniture products and the design types of them and from these evaluations suggested the design direction that can solve problems in development and improve the possibility of application of these energy sources to these street furniture items. Through these analyses, this study aims to enhance the image of future environment-friendly city and make new index for the application of alternative energy.

미국 대체농업의 경영 및 경제적인 연구 (RESEARCH ON MANAGEMENT AND ECONOMIC IN ALTERNATIVE AGRICULTURE IN THE UNITED STATES OF AMERICA)

  • 김종무
    • 한국유기농업학회지
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    • 제2권1호
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    • pp.16-23
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    • 1993
  • The traditional farming method has very long history in the process of agricultural development. The application of chemical fertilizers production became most popular to increase quantities of agricultural production. The United States of America is one of largest countries in the world. There are at present 50 States and farming conditions are very different from each individual States. There are increasing trend of agricultural production by applying chemical fertilizers as well as sprays during last 50 years(1940-90). The disadvantages of conventional farming method were to destroy nature and human life. There were some other kinds of disadvantages such as nitriated contamination in drinking water both for human being and animals. The alternative farming method is one of new farming method reducing and/of non-application of chemical fertilizers and sprays in agricultural production. There is less economic research on alternative farming system about $5.444 economic advatages in organic farms comparing commercial farms at the same area. There are advantage of higher unit price level in orgnic products, decreasing chemical costs as well as effect of crop combinations. It is certainly necessary to have more empirical research on economic and management of alternative farming method in the United States of America. However, if there is economic advantage in alternative farming methods, the future development possibility of alternative farming method can be very bright in vear future. There might be more advantages such as soil conservation, better quality of agricultural products, better health conditions of farmer's and consumer's as well as keeping healthy environment of rural and urban areas.

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대학도서관에서 대안적 리더십의 의미와 적용에 관한 고찰 (A Study on the Meaning and Application of Alternative Leadership in University Libraries)

  • 차현주
    • 한국비블리아학회지
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    • 제28권1호
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    • pp.253-270
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    • 2017
  • 지식시회에 있어서 대안적 리더십은 수평적, 정서적인 접근, 책임감을 통해 조직원들을 동기부여 하여 자발적 참여를 유도하게 한다. 대안적 리더십에 대한 이론적 연구와 대학도서관에서의 적용 가능성에 대한 이론적 논의는 거의 전무하다. 본 연구에서는 그 첫걸음으로 대안적 리더십들에 대한 이론적 고찰과 대학 도서관에서 지식경영 패러다임 변화, 관리자와 사서의 역할 변화와 대안적 리더십 적용에 대한 논의를 통해 대학도서관을 주도할 사서들의 리더십 강화를 위한 개발 방향을 제시하고자 한다.

염모제 도포방법에 따른 인체 적혈구의 산화스트레스 비교 (Comparison of Oxidative Stress in Red Blood Cells Induced by Hair Dyeing Application to Young Women)

  • 김영철;심미자;권정숙
    • Environmental Analysis Health and Toxicology
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    • 제19권2호
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    • pp.153-159
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    • 2004
  • To ascertain the effects of hair dyeing application on oxidative stress in human, a mixture of permanent black colored hair dye with the same amount of oxidant containing 6% hydrogen peroxide was used. A hair dyeing with contacting the scalp (conventional dyeing) and a hair dyeing with 3 to 4mm away from the scalp (alternative dyeing) were applied to each 15 young healthy women. Blood was taken from the brachial vein at two sampling times, just before and 6 hours alter the hair dyeing, and antioxidant enzyme activities and antioxidant contents were measured in red blood cells. After dyeing, malondialdehyde(MDA) contents for conventional dyeing group was shown to a tendence of more increased than alternative dyeing group. After dyeing, reduced glutathione (GSH) contents for conventional dyeing group was shown to a tendence of more decreased than alternative dyeing group. After dyeing, superoxide dismutase (SOD) and catalase (CAT) activities were significantly decreased in conventional dyeing group (p < 0.01), however, SOD and CAT activities were not significantly decreased in alternative dyeing group. After dyeing, there was no significant decrease in glutathione peroxidase (GPX) activity both for conventional dyeing group and alternative dyeing group. Therefore, after dyeing, the degree of oxidative stress in red blood cells for alternative dyeing group was appeared to be lower than conventional dyeing group.

Integration of the PubAnnotation ecosystem in the development of a web-based search tool for alternative methods

  • Neves, Mariana
    • Genomics & Informatics
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    • 제18권2호
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    • pp.18.1-18.5
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    • 2020
  • Finding publications that propose alternative methods to animal experiments is an important but time-consuming task since researchers need to perform various queries to literature databases and screen many articles to assess two important aspects: the relevance of the article to the research question, and whether the article's proposed approach qualifies to being an alternative method. We are currently developing a Web application to support finding alternative methods to animal experiments. The current (under development) version of the application utilizes external tools and resources for document processing, and relies on the PubAnnotation ecosystem for annotation querying, annotation storage, dictionary-based tagging of cell lines, and annotation visualization. Currently, our two PubAnnotation repositories for discourse elements contain annotations for more than 110k PubMed documents. Further, we created an annotator for cell lines that contain more than 196k terms from Cellosaurus. Finally, we are experimenting with TextAE for annotation visualization and for user feedback.

대체냉매 적용에 따른 밀폐형 압축기 저널베어링의 최적설계 (Optimum Design of Hermetic Compressor Joumal Bearing with Alternative Refrigerant Application)

  • 이규한;김정우;이장희
    • 한국윤활학회:학술대회논문집
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    • 한국윤활학회 1998년도 제27회 춘계학술대회
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    • pp.218-227
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    • 1998
  • Present study is undertaken to optimize the lubrication reliability and frictional loss of the dynamically-loaded journal bearing in hermetic reciprocating compressor with alternative refrigerant R600a application. Thermodynamic and dynamic analysis has been conducted to investigate cylinder pressure variations by substitution alternative refrigerant R600a for R12. The modeling of the dynamics of the compressor mechanism has been performed with lumped mass method. A mathematical model is developed for analyzing the dynamics of the journal bearing system with the mobility method. It takes into account the effects of the refrigerant species, aspect ratio, clearance ratio and surface roughness. A corresponding computer program is described which enables to obtain the minimum film thickness and frictional loss. Design optimization is graphically performed by parametric studies of the aspect ratio and clearance ratio.

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Classification of the Analytic Hierarchy Process Approaches by Application Circumstances

  • Yoon, Min-Suk;Kinoshita, Eizo
    • Management Science and Financial Engineering
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    • 제16권1호
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    • pp.17-46
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    • 2010
  • This paper studies six different AHP (Analytic Hierarchy Process) approaches and suggests that the features of the approaches are classified by application circumstances in order to contribute to the applicability and quality usage of the AHP. Our study investigates the hierarchical principles and characteristics of the AHP, and historical debates on the AHP evaluation in which the six approaches have been involved. One of six approaches is an ANP (Analytic Network Process) application that is directly connected to AHP usage. The application differences among the six approaches are validated with a plain example. Then, the four circumstances of AHP applications are classified by two dimensions: the first dimension is whether or not the importance (weights) of criteria is independent of restrictively setting alternatives, and the second dimension is whether or not preference (priorities) of alternatives is independent of adding alternative(s) to or removing alternative(s) from the considering set of alternatives. Then featuring way of weighting criteria is classified. We suggest the distinguishing manners and describe the implications of the AHP application. Finally, we discuss rank reversal and multiplicative AHP.

An alternative architecture for application-driven fuzzy systems

  • Pedrycz, W.;de Oliveira, J. Valente
    • 한국지능시스템학회:학술대회논문집
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    • 한국퍼지및지능시스템학회 1993년도 Fifth International Fuzzy Systems Association World Congress 93
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    • pp.985-988
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    • 1993
  • An alternative approach to the design of application-driven fuzzy systems is proposed. A broad class of fuzzy systems applications requires a certain fuzzy partition of the input space while it demands for simple numerical quantities. For this class, a dedicated fuzzy system archictecture is presented and a design strategy is proposed. Both the single-input/single-output and multi-input/multi-output cases are considered. Numerical analysis are complete illustrating several aspects of the proposed framework.

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Snap-Fit 통합잠금장치의 강도분석과 적용 (Intensity Analysis and Application of Integral Attachment in Snap-Fit)

  • 박범수;홍민성
    • 한국공작기계학회논문집
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    • 제15권6호
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    • pp.44-49
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    • 2006
  • The use of snap-fit features is highly recommended to reduce overall product cost and manufacturing time by reducing the number of parts and eliminating assembly with conventional fasteners. Application to particular product for integral attachment using snap-fit features is needed. Alternative attachment concept for specific application has been introduced. In this study, the optimal attachment design based on the given design objectives is identified using newly developed alternative attachment concept for the specific application to LCD monitor case assembly. Integral attachment using snap-fit features applies the systematic procedure and the intensity analysis.