• The Journal of The Korea Institute of Intelligent Transport Systems
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• 제10권3호
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• pp.36-46
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• 2011

At present, the number of local governments using the Traffic Information Center are increasing and drivers are utilizing its traffic information from VMS installed on roads in cities. However, the cases of the user's utility of VMS about urban roads with special characteristics different from expressways and urban highways haven't been evaluated so far. Because VMS is a medium installed from a budget to provide traffic information, it is necessary to evaluate and manage the efficiency of users. This study judged that the efficiency of the drivers using VMS of urban roads most influences the duty on alternative route information provision so that it established its evaluation criteria. In addition, it needs to raise its value by many drivers' observation of VMS. Therefore, in case of the same conditions, the installation location of VMS should be a road section with much traffic volume so its the evaluation criteria was established. At present, the study results can be utilized to raise the user's utility of VMS installed in the urban roads.

• IMMUNE NETWORK
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• 제15권2호
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• pp.83-90
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• 2015

Evaluation and screening of vaccines against tuberculosis depends on development of proper cost effective disease models along with identification of different immune markers that can be used as surrogate endpoints of protection in preclinical and clinical studies. The objective of the present study was therefore evaluation of subcutaneous model of M.tuberculosis infection along with investigation of different immune biomarkers of tuberculosis infection in BALB/c mice. Groups of mice were infected subcutaneously with two different doses : high ($2{\times}10^6CFU$) and low doses ($2{\times}10^2CFU$) of M.tuberculosis and immune markers including humoral and cellular markers were evaluated 30 days post M.tuberculosis infections. Based on results, we found that high dose of subcutaneous infection produced chronic disease with significant (p<0.001) production of immune markers of infection like $IFN{\gamma}$, heat shock antigens (65, 71) and antibody titres against panel of M.tuberculosis antigens (ESAT-6, CFP-10, Ag85B, 45kDa, GroES, Hsp-16) all of which correlated with high bacterial burden in lungs and spleen. To conclude high dose of subcutaneous infection produces chronic TB infection in mice and can be used as convenient alternative to aerosol models in resource limited settings. Moreover assessment of immune markers namely mycobacterial antigens and antibodies can provide us valuable insights on modulation of immune response post infection. However further investigations along with optimization of study protocols are needed to justify the outcome of present study and establish such markers as surrogate endpoints of vaccine protection in preclinical and clinical studies in future.

• Journal of Korean Neurosurgical Society
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• 제47권5호
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• pp.332-337
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• 2010

Objective : Although a transradial angiography is accepted as the gold standard for cardiovascular procedures, cerebral angiography has been performed via transfemoral approach in most institutions. The purpose of this study is to present our experience concerning the feasibility, efficacy, and safety of a transradial approach to cerebral angiography as an alternative to a transfemoral approach. Methods : Between February 2007 and October 2009, a total of 1,240 cerebral angiographies were performed via a transradial approach in a single center. The right radial approach was used as an initial access route. The procedure continued only after the ulnar artery was proven to provide satisfactory collateral perfusion according to two tests (a modified Allen's test and forearm angiography). Results : The procedural success rate was 94.8% with a mean duration of 28 minutes. All supra-aortic vessels were successfully catheterized with a success rate of 100%. The success rates of selective catheterization to the right vertebral artery, right internal carotid artery, left internal carotid artery, and left vertebral artery were 96.1%, 98.6%, 82.6% and 52.2%, respectively. The procedure was performed more than twice in 73 patients (5.9%), including up to 4 times in 2 patients. The radial artery occlusion was found in 4 patients (5.4%) on follow-up cerebral angiography, but no ischemic symptoms were observed in any of the cases. Conclusion : This study suggests that cerebral angiography using a transradial approach can be performed with minimal risk of morbidity. In particular, this procedure might be useful for follow-up angiographies and place less stress on patients.

• Journal of Environmental Impact Assessment
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• 제26권5호
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• pp.354-364
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• 2017

Considerable amount of resources on roads, basic infrastructure, to promote economic development and distribution of goods is invested. Despite the necessity, its undesirable side effects are various environmental problems In order to efficiently evaluate these problems more than before, planning indictors for environment-friendly road constructions is proposed in this study. First, we make an investigation into real-life cases where the extracted planning indicators were applied. Second, it is suggested that an alternative assessment method efficaciously evaluate and/or adopt extracted planning indictors on road construction projects. Finally, criteria to determine environmental impacts with respect to planning indicators and apply them into real cases is proposed. This study has its significance in upgrading past pro-environmental indictors for road construction, suggesting reasonable applications of planning indicators, and setting criteria to determine environmental impacts based on planning indicators.

• Journal of Korean Neurosurgical Society
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• 제29권8호
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• pp.1019-1023
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• 2000

Objective : Endoscopic third ventriculostomy is gaining popularity as a minimally invasive surgical option for certain types of hydrocephalus as an alternative to shunting. The authors have tried to fenestrate down to the subdural space passing through the prepontine cistern to lessen or avoid the chance of redoing due to healing. Materials and Method : A 48-year-old male patient with several years of intractable headache was presented. Magnetic Resonance Image(MRI) of the brain revealed marked ventricular dilatation with stenotic cerebral aqueduct. A 2.3mm flexible steerable endoscope($Neuroview^{(R)}$) was introduced via precoronal route and accessed to the third ventricular floor. Using 3-French Fogarty balloon catheter, thin third ventricular floor and the arachnoid membrane of the prepontine cistern were fenestrated, so called "double fenestration". To confirm the fenestration, subdural compa-rtment of the left abducens nerve was identified during the procedure. Forceful pulsating flow through the orifice convinced the patency of the opening. Results : The patient was discharged on the third postoperative day without any postoperative complications. The postoperative follow-up MRI of the brain, at second and sixth months, clearly demonstrated the flow void through the third ventricular floor. Conclusions : Endoscopic third ventriculostomy was successfully performed on an adult hydrocephalus patient with aqueduct stenosis. The third ventricular floor and arachnoid membrane of the prepontine cistern were fenestrated to achieve double fenestration to minimize the chance for failure. The details of this procedure and results are described.

• International Journal of Highway Engineering
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• 제13권1호
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• pp.149-156
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• 2011

Considerable evaluation is needed to design a new longitudinal tunnel in advance because it damaged drivers' driving safety and heightened the possibility of traffic accidents with its physical characteristics. Specifically, considering traffic psychological and ergonomic factors was very important to prevent the difficulty of maintaining safe speed, the increase of the drowsy driving, the fatality of traffic accidents, and subjective feelings such as anxiety while driving a car through the tunnel, from design to construction. This study dealt with driving safety evaluation of an original road alignment design for the longitudinal tunnel (length: above 10km) with a driving simulator, and helped us to improve an original road alignment design and make an alternative road alignment design with presenting risky districts. The results of experiment showed that inflection points were revealed more risky districts, because they impaired driving safety and elevated driver workload while driving a car through around the inflection points of two-way route. Finally, the limitations and implications of this study were discussed.

• Journal of the Korean Geotechnical Society
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• 제27권4호
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• pp.33-41
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• 2011

A railway embankment route extending to 2 km was laid on normally consolidated clay in the West Gimhae Plain. This embankment was first built using the stage-construction technique, but longitudinal cracks suggesting arc sliding appeared on the surface of the embankment immediately after the first stage of its construction. As an alternative, the piled raft was installed on the failed embankment and then the remaining height of the embankment was raised. The behavior of the piled raft was monitored with different instruments during construction. This paper describes the monitoring results and analyses. The results show that if the pile group essentially exhibits the behavior of friction piles, the piled raft foundation performs well even in normally consolidated soft clay.

• Journal of the Korean Institute of Landscape Architecture
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• 제33권4호
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• pp.33-44
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• 2005

In order to reveal the geographical landscape's features of the East Sea-gateway(東海口), which has existed only in the era of Shilla as unique east path, we have carried out analysis of the old maps(邑誌圖) and satellite imagery, and geographical features analysis in the application of digital maps, and the result is as follows. 1. Analysis of materials from the Chosun dynasty describes landscapes called sea gates(海口) (note that this should not be capitalized); a place where the river meets the sea and the sea comes far into the land. Sea gate landscapes may have an island, but this is not a prerequisite. 2. According to the satellite imagery, the capital city of Shilla Dynasty had five passages. four or them are broad corridors, but one of them is narrow. The east side of the capital city is blocked by mountains and there was an important path which leads into the East Sea. 3. According to the cross section of the mountains, there is the only rule East-path. There was no alternative way. There was only one way-out to the east side from the capital city. This is the unique path which reaches a length of 28km. Judging from this, it seems that this path was called the East Sea-gateway. 4. The landscape of the East Sea-gateway was shaped like the letter 'V' and reached to the landscape of the sea gate. However, the route was blocked - part by the mountains, and also the part in the crisis of loss of path-landscape which has lost its own character of closure as several valleys are merged together.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• 제4권1호
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• pp.1-13
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• 2005

For integrated transit networks operated with diverse transit modes, it is difficult to find related literatures on the provision of multiple travel time routes information. This study proposes a methodology on how to select K number of least time transit routes in the integrated transit network with two modes, bus and subway. In the Proposed method, three constraints usually (will be) encountered for decision by users-(1) service time constraints of travel modes, (2) maximum payment fare constraints under the integrated distance based fare system, and (3) maximum number of transfer constraints - are taken into consideration in the searched routes. The experimental studies shows that the proposed method properly provides K number of least time routes. In addition, it somehow proves that by combinatorially considering three constraints the proposed method can be evaluated as to enlarge the quality as well as the diversity of route information demanded by users.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• 제2권1호
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• pp.85-92
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• 2003

Due to the expansion of freeway networks in Korea, drivers have more routes to choose. Traffic information on various alternative roadway sections and routes may help drivers choose the optimal route that minimizes travel time or cost. Traffic information on roadways is, therefore, invaluable in sense that individual drivers could reduce their travel time or cost by selecting optimal routes, and furthermore total travel cost of the system could be lowered. However, consensus about the price of traffic information that drivers are willing to pay is not made yet. Current price of traffic information is decided according to the price of similar information such as stock, weather and so on. To investigate the value of traffic information, a survey was conducted at freeway rest areas near Seoul Megalopolis area including Kyunggi Province. Eight hundred drivers who had travelled on freeway within a year were randomly selected. Purposive Quota Sampling was used. A price-response function, a relationship between price and sales, was obtained based on the survey, followed by sensitivity analysis