• Title/Summary/Keyword: Aloe spp.

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Isolation of Ethanol Metabolizing Enzyme Inhibitors from Aloe spp.

  • Shin, Kuk-Hyun;Woo, Won-Sick;Chung, Ha-Sook;Shim, Chang-Sub
    • Natural Product Sciences
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    • v.1 no.1
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    • pp.55-60
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    • 1995
  • In the course of evaluation of hepatoprotective components against alcohol-induced toxicity from Aloe spp., the methanol extract was found to cause a significant inhibition of rat liver cytosolic alcohol dehydrogenase activity. Systematic fractionation of active tractions monitored by bioassay led to isolation of four compounds; aloe-emodin, aloenin, ethylidene-aloenin and ${\beta}-sitosterol$, which were estimated as active principles for inhibition of c-ADH and c-ALDH activities in vitro.

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Effects of High Molecular Weight Fractions of Aloe spp. on Alcohol Metabolism (Aloe속 식물의 고분자물질 분획이 알콜대사에 미치는 효과)

  • Han, Yong-Nam;Chung, Ha-Sook;Lim, Soon-Sung;Lee, Sang-Hyun;Shim, Chang-Sub;Shin, Kuk-Hyun
    • Korean Journal of Pharmacognosy
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    • v.29 no.2
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    • pp.120-124
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    • 1998
  • For the purpose of evaluating protective components against alcohol-induced toxicity, the active components enhancing alcohol metabolism was pursued from water soluble fraction by ethanol precipitation and DEAE-cellulose chromatographic technique. As a result, various high molecular weight fractions from Aloe vera and Aloe arborescens, on a single oral administration in rats were found to cause a significant decrease in the blood ethanol concentration as well as enhancement of liver cytosolic ADH and ALDH activities and among which, a strong acidic high molecular weight fraction was demonstrated to exhibit the most potent enhancing activity on ethanol metabolism.

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Genetic relationship of Aloe vera 'Saengjang', a new forma, based on cpDNA and ITS sequence variation (cpDNA와 ITS 염기변이에 근거한 신품종 생장알로에 유전적 상관관계)

  • Srikanth, Krishnamoorthy;Jang, Seon Il;Whang, Sung Soo
    • Korean Journal of Plant Taxonomy
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    • v.44 no.4
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    • pp.250-256
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    • 2014
  • This study was carried out to understand the genetic relationship of three Aloe spp. cultivated in Korea, A. saponaria, A. vera and A. arborescens and a new variant in Korea based on three plastid (matK, trnL-F, rbcL) and one nuclear (ITS regions) DNA barcode markers. A total of 2,420 bp sequence was amplified. Two indels were detected in the trnL region, and also several species specific nucleotide loci were detected in all 29 parsimonious informative sites, and 148 variable sites were detected among four taxa studied while 170 variable and 75 parsimonious sites were detected when other Aloe spp. in worldwide were used. An UPGMA phenogram with 10,000 bootstrap replication showed that the new variant was closest to A. vera. The variant was not morphologically and genetically concurrent with any reported species so far. The clustering of Aloe species were broadly in agreement with previously reported results.

Effect of Polyamines, Salt Strength, Sucrose, and Gelling Agents on plant Regeneration from Meristem Culture of Aloe spp. (알로에 생장점 배양시 식물체 재분화에 미치는 Polyamine, 염류농도, 당 및 Gelling Agent의 효과)

  • Yu, Chang-Yeon;Kim, Jae-Kwang;Lim, Jung-Dae
    • Korean Journal of Medicinal Crop Science
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    • v.5 no.3
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    • pp.186-190
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    • 1997
  • This study was carried out to investigate the effect of polyamines, salt strength. sucrose and gelling agents on the regeneration of plantlets by meristem culture of Aloe arborescens Mill. and Aloe vera L.. Shoot multiplication was more effective when 10mg/ l spermine in Aloe arborescens and 1mg/ l spermidine in Aloe vera added into MS medium than when other polyamines were treated into media. A quarter strength of MS medium was effective for rooting of shoots regenerated. Higher concentration of sucrose (45g/ l) was more effective for shoot regeneration. Addition of 4g/ l gelrite into the medium was effective for induction of multiple shoots from Aloe than that of agar or other concentrations of gelrite. When plantlets regenerated from meristem culture were transferred to pot. survival rate of plantlets was 80% on perlite and was 95% on vermiculite. respectively.

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Studies on the Effect of Aloe spp. on Ethanol Methabolism (I). -Effect of Aloe vera on Serum Ethanol Level and Hepatic ADH Activity- (Aloe속 식물이 알콜대사에 미치는 작용에 관한 연구(1) -Aloe vera가 알콜 및 알콜대사효소에 미치는 효과-)

  • Shin, Kuk-Hyun;Woo, Won-Sick;Song, Young-Jin;Chung, Ha-Sook;Lee, Jung-Mi;Shm, Chang-Sub
    • Korean Journal of Pharmacognosy
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    • v.26 no.2
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    • pp.148-153
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    • 1995
  • As an initial step for evaluating hepatoprotective components against alcohol-induced toxicity, the effect of various fractions from Aloe vera on alcohol metabolism in rats were examined and the results were as follows: Water soluble fraction, after a single oral administration to rats, was found to cause a significant decrease in the serum ethanol concentration as well as enhancement of liver cytosolic ADH activity. On the other hand, the fractions soluble in organic solvent was found to cause an increase in the blood ethanol concentration and inhibit ADH activity. Further fractionation of the water soluble fraction by ultrafiltration system gave four subfractions corresponding to molecular weight and treatment of them in rats demonstrated that subfraction of M.W. > 30,000 exhibited the most potent enhancing activity of ethanol methabolism.

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Microbiological Hazard Analysis of Botanical Raw Materials used for Functional Health Foods and Preliminary Screening for Irradiation of Aloe Powder Products (건강기능식품 중 주요 식물성 원료에 대한 미생물학적 위해 분석과 알로에 제품에 대한 방사선 조사 가능성 검지)

  • Sung, Dong-Eun;Lee, Jee-Hye;Oh, Sang-Suk
    • Journal of Food Hygiene and Safety
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    • v.22 no.1
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    • pp.15-22
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    • 2007
  • Health functional foods refer to food which manufactured in the form of a tablet, capsule, granule or pill, using materials and ingredients with useful function for a human body in Korea. It needs to be confirmed as safe. Microbiological analyses on 37 samples of botanical raw materials used in the health functional food were performed. Microbiological analyses and probability of irradiation using PSL on 4 samples of aloe powder products were studied. In health functional food ingredients APC was $10^{3}-10^{6}\;CFU/g$ and coliform counts were $10^{2}-10^{5}\;CFU/g$. Among 37 samples B. cereus were found in 12 samples. Four samples of aloe powder products were tested for possible irradiation using preliminary PSL, Two samples of aloe powder products showed positive on preliminary PSL test for irradiation.