• Mass Spectrometry Letters
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• 제13권3호
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• pp.49-57
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• 2022

During electrospray ionization mass spectrometry (ESI-MS) analysis of proteins, the addition of supercharging agents allows for adjusting the maximal charge state, affecting the charge state distribution, and increases the number of ions reaching the detector thus, improving signal detection. We postulate that in di-substituted arene isomers, molecules with higher polarizability values should generate greater interactions and hence elicit higher signal intensities. Polarizability is an electronic parameter which has been demonstrated to predict many chemical interactions. Many properties can be predicted based on charge polarization. Molecular polarizability is a vital descriptor for explaining intermolecular interactions. We employed DFT (density functional/Hartree-Fock hybrid model, B3LYP)-derived descriptors and computed molecular polarizability for ten disubstituted arene reagents, each set made up of three (ortho, meta, para) isomers, with reported use as supercharging reagents during ESI experiments. The atomic electronic inputs were ionization potential (IP), electron affinity (EA), electronegativity (𝛘), hardness (η), chemical potential (µ), and dipole moment (D). We determined that the para isomers showed the highest polarizability values in nine of the ten sets. There was no difference between the ortho and meta isomers. Polarizability also increased with increasing complexity of the substituents on the benzene ring. Polarizability correlated positively with IP, EA, 𝛘, η, and D but correlated negatively with chemical potential. This DFT study predicts that the para isomers of di-substituted arene isomers should elicit the strongest ESI responses. An experimental comparison of the three isomers, especially of larger supercharging molecules, could be carried out to establish this premise.

• 대한방사선기술학회지:방사선기술과학
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• 제8권2호
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• pp.89-91
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• 1985

• 대한방사선기술학회지:방사선기술과학
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• 제9권1호
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• pp.83-87
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• 1986

• 한국간호교육학회지
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• 제22권1호
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• pp.83-95
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• 2016

Purpose: This study aims to identify perception, performance, and the related factors of performance in regards to patients' medical information protection among allied health college students. Methods: Four hundred twelve subjects from three colleges located in Jeonbuk and Kyungbuk province consented to participate. Data was collected from November 28 to December 15, 2012. To assess perception and performance in regards to patients' medical information protection, a self-reporting questionnaire was used. Data was analyzed via SPSS 18.0 program. Results: The score of perception and performance about patients' medical information protection were 4.07 and 3.56, respectively. All item's scores of performance were significantly lower than those of perception. The perception score was significantly different according to recognition of hospital ethics code (t=1.95, p=.052), and recognition of association ethics code (t=2.88, p=.004). The performance score was significantly different according to gender (t=-3.32, p=001), major (F=14.41, p<.001), clinical practicum hospitals (F=8.22, p<.001), and method of electronic medical record access (F=3.23, p=.023). The factors influencing performance were perception(${\beta}=.46$, p<.001), duration of clinical practice(${\beta}=-.36$, p<.001), and gender(${\beta}=.09$, p=.033). Conclusion: In order to improve performance in regards to patients' medical information protection of allied health college students, we should develop ethical education programs and standardize them through multidisciplinary collaboration.

• 대한방사선기술학회지:방사선기술과학
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• 제9권1호
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• pp.131-135
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• 1986

The reciprocity law failure of the blue sensitive screen-film system was treasured, by authors. As a result, it has been found that reciprocity law failure is mote likely to occur at lower exposure, lower density and higher development temperature.

• Physical Therapy Rehabilitation Science
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• 제2권2호
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• pp.92-98
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• 2013

Objective: Constraint induced aphasia therapy (CIAT) is a more intensive form of language treatment for aphasia as compared to traditional treatments. This study examined whether there are differences in cortisol stress levels between the two methods of aphasia treatment as well as effects on language skills. Design: Randomized controlled trial. Methods: A total of 20 participants with expressive aphasia were randomly placed into one of the two treatment groups. The CIAT group received 10 days of intensive treatment over two weeks. The traditional therapy group received 6 days of treatment over 2 weeks. All participants in each group provided salivary cortisol samples before treatment, at the mid-point of treatment, and at the conclusion of treatment. Language skills were assessed before treatment and at the conclusion of treatment. Results: A significantly higher proportion of individuals in the CIAT treatment group had increased salivary cortisol stress levels when compared to the traditional treatment group at the mid-point of the program (80% versus 30% respectively, p<0.05). There was no significant difference in the proportion of individuals with increased cortisol stress by the end of the treatment. Language scores for word repetition and overall aphasia quotient significantly improved for the CIAT group when compared to the traditional group (p<0.05). Conclusions: The CIAT treatment appears to initially create increased psychophysiological stress as compared to the traditional treatment. In spite of the initial increases in psychophysiological stress, participants appear to become conditioned to the challenge and ultimately have enhanced benefit from CIAT treatment.

• Journal of Ginseng Research
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• 제17권3호
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• pp.287-306
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• 1993

• 대한방사선기술학회지:방사선기술과학
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• 제13권2호
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• pp.1-14
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• 1990

As the institute of education teaching radiologic technology in Korea, different from others, junior college is the only institute which has been managed for it as a two-year educational course for 27 years since 1963 when it was established for the first time in our country irrespective of the needs of the times. But according to the development of medical equipment, variety of medical skill, increase of medical demands now a days, the supply of radiologic technology in modern medicine not only makes it advance as an inevitable factor but also broadens the area of its business systematically. Therefore, we got the following results after we had considered the necessity to lengthen the term of education and searched for the most reasonable way. 1. The term of study of the radiologic technologists in junior college must be lengthened to 3 years from 2 or 3 years regulated in the law of education. 2. In three-year curriculum, the subjects like basic medical science, science and engineering and ultramodern science, etc., which are lated to the new radiologic science must be taught in the junior colleges, and hospital practice also must be a compulsory subject in curriculum. 3. As the school years becomes longer, a lot of programs to make the study effective must be searched, researched and propelled forward.

• Parasites, Hosts and Diseases
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• 제57권4호
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• pp.341-357
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• 2019

Acanthamoeba, one of free-living amoebae (FLA), remains a high risk of direct contact with this protozoan parasite which is ubiquitous in nature and man-made environment. This pathogenic FLA can cause sight-threatening amoebic keratitis (AK) and fatal granulomatous amoebic encephalitis (GAE) though these cases may not commonly be reported in our clinical settings. Acanthamoeba has been detected from different environmental sources namely; soil, water, hotspring, swimming pool, air-conditioner, or contact lens storage cases. The identification of Acanthamoeba is based on morphological appearance and molecular techniques using PCR and DNA sequencing for clinico-epidemiological purposes. Recent treatments have long been ineffective against Acanthamoeba cyst, novel anti-Acanthamoeba agents have therefore been extensively investigated. There are efforts to utilize synthetic chemicals, lead compounds from medicinal plant extracts, and animal products to combat Acanthamoeba infection. Applied nanotechnology, an advanced technology, has shown to enhance the anti-Acanthamoeba activity in the encapsulated nanoparticles leading to new therapeutic options. This review attempts to provide an overview of the available data and studies on the occurrence of pathogenic Acanthamoeba among the Association of Southeast Asian Nations (ASEAN) members with the aim of identifying some potential contributing factors such as distribution, demographic profile of the patients, possible source of the parasite, mode of transmission and treatment. Further, this review attempts to provide future direction for prevention and control of the Acanthamoeba infection.

• 대한방사선기술학회지:방사선기술과학
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• 제10권1호
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• pp.43-47
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• 1987

Authors have tested on the characteristics, image qualities and clinical applications of Konica Hi-ortho X-ray film MGH. The results are as followed; 1. The speeds of KM/MG, MGH were as about 2.7 times, and those of KR/MG, MGH were as about 4.5 times as compared with LT-II/A and the tube voltage influenced upon KM/MG, MGH over 80 kVp, upon KR/MG, MGH over 90kVp. 2. Good image definition by the detection of Burger Phanton KM/MGH, KM/MG, and LT-II/A, and good I.Q. values by the detection of Hawlet Chart LT-II/A, KM/MGH, and KM/MG in that order. Therefore, MGH film could reduce the patient dose steeply, and furthermore, provide high image quality by the high contrast and then, it will be very useful to abdominal angiography and cerebral angiography.