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Effects of Feeding a Combination of Probiotics Containing Lactobacillus plantarum and Bacillus Subtilis on Immune Response and Diarrhea Incidence in Post-weaning Piglets (이유자돈에 대한 Lactobacillus plantarum과 Bacillus subtilis 합제 투여에 따른 면역반응과 설사발생에 미치는 효과)

  • Park, Eun-Kee;Yoo, Eun-Ah;Cha, Chun-Nam;Tutkun, Engin;Kim, Suk;Lee, Hu-Jang
    • Journal of Veterinary Clinics
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    • v.30 no.6
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    • pp.459-463
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    • 2013
  • A study investigated the effects of a mixture of Lactobacillus plantarum (L. plantarum) and Bacillus subtilis (B. subtilis) on diarrhea incidence, immune response, and fecal microflora counts in post-weaning piglets. One hundred 28-day-old piglets were randomly assigned to five treatment groups: negative control (NC), free of antibiotics; positive control (PC), 0.03% chlortetracycline; LB 1, a mixture of L. plantarum and B. subtilis (LB) 0.5 kg/ton feed; LB 2, LB 1.0 kg/ton feed; and LB 3, LB 2.0 kg/ton feed. Diarrhea scores for LB 2 and LB 3 from the 2nd week were significantly reduced compared to NC (P<0.05). In terms of the level of IgG and IFN-${\gamma}$, all treatment groups were significantly higher than NC (P<0.05), and the IgG level of LB 3 was significantly higher than that of PC (P<0.05). Furthermore, fecal lactic acid bacteria (LAB) counts for LB 2 and LB 3 were significantly higher than those of NC and PC (P<0.05). In addition, fecal Enterobacteriaceae (ENT) counts for PC, LB 2 and LB 3 were significantly lower than those of NC (P<0.05). Based on the results from this study, it was concluded that a combination of L. plantarum and B. subtilis strains could be used as potential alternatives to antibiotics to prevent diarrhea incidence in piglets.

Computerized Order Communication System for Out-patient's Clinic Using Personal Computer and Local Area Network (PC 및 LAN을 이용한 외래처방 전달 시스템)

  • 김남현;김원기
    • Journal of Biomedical Engineering Research
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    • v.14 no.4
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    • pp.321-326
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    • 1993
  • Recently, microcomputer technology has been developed rapidly and it provides not only graphic user interface that can be fraendly accessable but also large storage capacity to han- dle much hospital information. Almost all the order communication system for hospital has been developed under the concept of host and terminal environment since last 20 years. However, host-terminal system has not been successful in korea simply because most of physicians prescibe for rrlany patients a day(sometimes more than 150 patients a day). Also, under the host-terminal environment, programs are not friendly implemented for users. Since March 1991, we had developed order communication system for out-patients(named YONSEI-PC) using personal computer(PC) and local area network(LAN) . Since September 1992, we has applied succesfully in the Yonsei Cardiovascular Center, Sevrance Hospital, Yonsei University College of Medicine. This system consisted with Server and Clients which is communicated through LAN(Ethernet). The system also use the Host computer(IBM 9221 170) as a data bank and communicates to the Server with emulation card(3270 emulator, Interlink Inc., Korea) . After introducing this system, it enables patients to receive drugs witllin 20 minutes after prescription of 300-400 patients per day and it seemed to be effective system not to reduce waiting time for the patients but also to remove charge-troubling(due to His-entry of prescription) . This system also seems to be effective in terms of office automatism for hospital management. However users, usually physitions, required more friendly and easy system to operate and we thought that the most important one to successfully introduce order communication computer system in the hospital is user interface.

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Detection, Identification and Surveillance System Development of Illegal Fishing Vessels in Inshore Fishing Ground (연안 어장에서의 불법 조업 어선의 탐지, 식별 및 감시 시스템 개발)

  • LEE Dae-Jae;KIM Kwang-Sik
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.37 no.4
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    • pp.337-344
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    • 2004
  • A real-time surveillance system of the inshore fishing ground was constructed to identify and detect discrete targets, such as illegal fishing vessels. This paper describes measurements made with a combination of sensors, such as radar, CCTV camera, and GPS receivers, for monitoring the fishing activity of small vessels within the fishing limit zones of the inshore waters. The CCTV camera system was used to confirm detection and to classify the type of target. The location of legal vessels distributed in coastal waters was acquired from each GPS system of ships connected to commercial satellite communication network. The surveillance system was networked via LAN to one host PC with the use of electronic navigational charts (ENC) and a radar link. Radar Target Extractor (RTX) for radar signal processing can be remotely accessed and controlled on existing PC via the internet, from anywhere, at any time. Results are presented that demonstrate the effectiveness of the newly constructed fisheries monitoring system for conducting continuous surveillance of illegal fishing vessels in the inshore fishing ground. The identification of illegal fishing vessels was achieved by comparing radar positions of illegal fishing vessels exceeding the warning limits in the surveillance area with GPS position reports transmitted from legal fishing vessels, and the illegal fishing vessels were marked with red symbols on the ENC screen of a PC. The methods to track the activities of all vessels intruding or leaving the fishing limit zones also were discussed.

Disease examination of slaughter pigs from Southern Gyeonggi-do (도축병변을 통한 돼지의 질병감염 조사)

  • Woo, Jong-Tae;Cheong, Yeon-Hee;Kim, Min-Kyoung;Ku, Kyung-Nyer
    • Korean Journal of Veterinary Service
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    • v.33 no.1
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    • pp.67-74
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    • 2010
  • To reduce an economic loss by swine disease, this study was designed to provide helpful data which are particularly useful for each individual farm. From february to December 2009, a total of 18,173 slaughter pigs (612 herds) were randomly sampled, which were produced just in southern region of Gyeonggi-do. We examined all of them for the slaughter lesions of 8 kind diseases such as swine enzootic pneumonia (SEP), pleuritis (PL), pleuropneumonia (PP), white milk spot in liver (WMS), papular dermitis (PD), pericarditis (PC), ileitis (IL) and peritonitis (PT). Twenty four percentages (4431/18173 pigs) of the examined pigs had no lesions about 8 kind diseases. Among the pigs with lesions, the numbers of the pigs with just one lesion were 7,637(42%), followed by 4,551(25%) pigs with 2 lesions. Average prevalence of pigs were 56.5% (10288/18173 pigs) in SEP, followed by 34% in PL, 12.4% in PP, 10.1% in WMS, 6.1% in PD, 4.7% in PC, 0.1% in IL and PT, respectively. Each prevalence of SEP, PL, PP and PD was higher in spring than in winter, respectively (P<0.01). Among the pigs (n=6,105) with 2 or more than 2 kinds of lesions the top (55.5%) was the pigs with SEP and PL, and the second was 1,179 (19.3%). Swine enzootic pneumonia was considered as one of the more likely risk factors for initiation or/and acceleration of other diseases such as PL, PP, WMS and PD. The lesion of SEP was relatively severe since the pigs with late stage were more (7,277 pigs) than those with early stage.

A Study on the Safety for Pedestrians Waiting for Signal (보행신호를 대기하는 보행자의 안전에 관한 연구)

  • Kim, Hansol;Baek, Seryong;Choi, Yongsoon;Yoon, Junkyu;Lim, Jonghan
    • Journal of Auto-vehicle Safety Association
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    • v.13 no.3
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    • pp.41-46
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    • 2021
  • The number of big traffic accident cases of pedestrian death appeared to be minor, however compared to death rate in car to car accidents is very high and quite a few of the pedestrian death rates among all traffic accidents are counted to be almost 40%. Previous pedestrian safety studies were mostly aimed at reducing the degree of pedestrian injuries from a vehicle to pedestrian collision, and less at preventing a collision itself. This research was conducted with a method of using road facilities to prevent vehicles from rushing into the sidewalk. This research used one of the collision analyzing programs, called PC-Crash to simulate the vehicle rushing into the sidewalk. Based on the program, it could derive an optimal safe zone location where the pedestrian can wait for the pedestrian light safely. Also, changing road facilities such as pedestrian light pillars or signal controllers can widen 440% compared to the present safe zone. Accordingly, researchers have to consider a method to analyze and apply pedestrian safe zones along with road facilities location when designing a road.

Use of Wing Feather Loss to Examine Age-Related Molt in Oriental Storks (Ciconia boyciana)

  • Yoon, Jongmin;Yoon, Hyun-Ju;Nam, Hyungkyu;Choi, Seung-Hye
    • Proceedings of the National Institute of Ecology of the Republic of Korea
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    • v.2 no.1
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    • pp.26-31
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    • 2021
  • Reproduction and molt are costly processes in avian life histories. These two fitness-related traits are expected to be under one of physiological trade-offs. Age-related molt is known to be higher in young birds than that in adults presumably due to the cost of reproduction in adults. The present study partially replicated a previous study using a non-invasive method of seasonal wing feather loss instead of capture-inspection for molting progress in oriental storks (Ciconia boyciana). We first examined characteristics of the known six wing feather types (i.e., primaries [P], primary coverts [PC], secondaries [S], secondary coverts [SC], and tertials [T]) from two specimens with four wings. Results were utilized as references for further investigation. We then collected a total of 3,807 wing feathers shedded by 61 captive storks for one year and classified them into six wing feather types based on the reference with structures of vane (i.e., how asymmetrical) and calamus (i.e., how rigidly attached to skin) of wing feathers. Our results indicated that annual losses of all six-type wing feathers decreased with increasing ages, ranging from 29% to 58% for PC, alula, SC, P, S, and T in order. Our results were also comparable to those of a former study, suggesting that the pattern of age-specific molt might be associated with the cost of reproduction in adults. However, juveniles might shed more wing feathers with low quality formed during the previous development stage than older birds.

A Study on Shear Bond Strength of Heat Press Ceramic to Non Precious Porcelain Metal (도재용착용 비귀금속과 열가압성형도재의 전단결합강도 연구)

  • Kim, Seong-Soo;Kim, Wook-Tae;Lee, Myung-Kon
    • Journal of Technologic Dentistry
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    • v.33 no.1
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    • pp.37-45
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    • 2011
  • Purpose: Heat pressed ceramics, used for all ceramic restorations, have the additional advantage of being technically less change through using of the lost-wax technique. Conceptually, combining the ceramic with the clinically proven reinforcing ability of a metal framework would be advantageous; however, cause of mismatching of fusion between ceramics and metal frameworks which from differences of casting temperature and coefficient of thermal expansion, pressed ceramics could not be used with a metal framework. The purpose of this study was to compare shear bond strength of press-to metal ceramic to porcelain fused non precious metal and feldspatic porcelain fused non precious metal. Methods: The 30 metal specimens were casted in a porcelain fused non precious metal nickel-chromium alloy. They were divided into 3 groups by surface treatment and applied ceramic: $125{\mu}m$ aluminium oxide sandblasting and veneered feldspatic porcelain (group FP), $125{\mu}m$ aluminium oxide sandblasting and had press-to-metal ceramic applied (group PC), porcelain bonder (gold bonder) fused on surface of metal specimens and had press-to-metal ceramic applied (group PCG). In each group 10 metal specimens were used. The press-to-metal ceramic applied 20 specimens had ash-free wax pattern applied, the metal-wax complexes invested, and were pressed with heat press ceramic. All specimens were subjected to shear bond strength test at a crosshead speed of 1.0 mm/min. Results: The results of measured in Mean SD and data were analyzed by one-way AVOVA (p= .05) and Tukey HSD test (p= .05).: group FP $16.090{\pm}1.841$ MPa, group PC $12.620{\pm}1.8256$ MPa, group PCG $10.920{\pm}0.9283$, significant differences between all groups (p < .05). Significant differences were found in each between group FP and group PC, group FP and group PCG (p < .05). Conclusion: The shear bond strength of press-to-metal ceramic to porcelain fused non precious metal was described higher in unused gold bonder group than used gold bonder groups.

Comparative effects of dietary functional nutrients on growth performance, meat quality, immune responses, and stress biomarkers in broiler chickens raised under heat stress conditions

  • Kim, Deok Yun;Kim, Jong Hyuk;Choi, Won Jun;Han, Gi Ppeum;Kil, Dong Yong
    • Animal Bioscience
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    • v.34 no.11
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    • pp.1839-1848
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    • 2021
  • Objective: The objective of the present study was to investigate the comparative effects of dietary functional nutrients including glutamine (Gln), chromium picolinate (Cr picolinate), vitamin C (Vit C), betaine (Bet), and taurine (Tau) on growth performance, meat quality, immune responses, and stress biomarkers in broiler chickens raised under heat stress conditions. Methods: A total of 420 21-d-old Ross 308 male broiler chickens (initial body weight = 866±61.9 g) were randomly allotted to 1 of 7 treatment groups with 6 replicates. One group was kept under thermoneutral conditions and was fed a basal diet (PC, positive control). Other 6 groups were exposed to a cyclic heat stress condition. One of the 6 groups was fed the basal diet (NC, negative control), whereas 5 other groups were fed the basal diet supplemented with 0.5% Gln, 500 ppb Cr picolinate, 250 mg/kg Vit C, 0.2% Bet, or 1.0% Tau. The diets and water were provided ad libitum for 21 d. Results: Broiler chickens in NC group had decreased (p<0.05) growth performance and immune responses measured based on cutaneous basophil hypersensitivity (CBH), but increased (p<0.05) stress responses measured based on feather corticosterone concentrations and blood heterophil:lymphocyte than those in PC group. However, none of dietary functional nutrients had a positive effect on growth performance of broiler chickens. Dietary supplementation of 250 mg/kg Vit C improved (p<0.05) CBH responses of broiler chickens, but other functional nutrients had no such an improvement in CBH responses. All functional nutrients decreased (p<0.05) stress responses of broiler chickens. Conclusion: Functional nutrients including Gln, Cr picolinate, Vit C, Bet, and Tau at the supplemental levels used in this study decrease stress responses of broiler chickens to a relatively similar extent. However, this reduction in stress responses could not fully ameliorate decreased productive performance of broiler chickens raised under the current heat stress conditions.

Castleman's Disease of the Neck and Mediastinum (경부와 종격동에 발생한 캐슬만씨 병(Castleman's Disease))

  • Nam Kee-Hyun;Choi Hyun-Ho;Lim Chi-Young;Lee Jan-Dee;Kim Seung-Il;Chang Hang-Seok;Hong Soon-Won;Park Cheong-Soo
    • Korean Journal of Head & Neck Oncology
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    • v.21 no.1
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    • pp.48-52
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    • 2005
  • Objectives: Castleman's disease(CD) is a lymphoproliferative disorder of unknown etiology. To elucidate the clinicopathologic characteristics of CD, we retrospectively reviewed our experience. Methods: Fifteen patients with CD of the neck and mediastinum were identified. Patients were divided into two groups: group I had an unicentric CD and group II had multicentric CD. The histology of CD was divided into 3 subtypes: hyaline-vascular(HV), plasma cell(PC), and mixed. Results: The study included 12 cases of group I, 3 cases of group II in the clinical aspect and 10 cases with HV, 3 cases with PC, 2 cases with mixed type in the histologic aspect. Of group I patients who underwent complete surgical excision, all are currently free of disease. The clinical course of group II patients was variable. Of two patients with multicentric plasma cell CD who were treated, one remain free from disease and the other had a local recurrence in the neck. One patient with multicentric mixed CD died of disease after 30 months of presentation. Conclusion: Surgical resection is recommend for patients with the unicentric CD, regardless of histologic subtype. Patients with multicentric disease do not benefit from surgical resection and should be candidates for multimodality therapy.

MNDO Studies on Intramolecular Proton Transfer Equilibria of Acetamide and Methyl Carbamate$^1$

  • Lee, Ik-Choon;Kim, Chang-Kon;Seo, Heon-Su
    • Bulletin of the Korean Chemical Society
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    • v.7 no.5
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    • pp.395-399
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    • 1986
  • Intramolecular proton transfer equilibria of acetamide and methyl carbamate have been studied theoretically by MNDO MO method. For both substrates, carbonyl-O protonated tautomer was found to be the most stable form, the next most stable one being N-protonated form. Gas phase proton transfers take place by the 1,3-proton rearrangement process and in all cases have prohibitively high activation barriers. When however one solvate water molecule participates in the process, the barriers are lowered substantially and the process proceeds in an intermolecular manner through the intermediacy of the water molecule via a triple-well type potential energy surface; three wells correspond to reactant(RC), intermediate(IC) and product complex(PC) of proton donor-acceptor pairs whereas two transition states(TS) have proton-bridge structure. General scheme of the process can be represented for a substrate with two basic centers(heteroatoms) of A and B as, $$ABH\limits^+\;+\;H_2O\;{\to}\;ABH\limits^+{\cdots}{\limits_{RC}}OH_2\;{\to}\;AB{\cdots}H\limits_{TS}^+{\cdots}{\limits_{1}}OH_2\;{\to}\;AB{\cdots}{\limits_{IC}}H\limits^+OH_2\;{\to}\;BA{\cdots}H\limits_{TS}^+{\cdots}{\limits_{2}}OH_2\;{\to}\;BA H\limits^+{\cdots}{\limits_{PC}}OH_2\;{\to}\;BAH\limits^+\;+\;H_2O$$ Involvement of a second solvate water had negligible effect on the relative stabilities of the tautomers but lowered barrier heights by 5∼6 Kcal/mol. It was calculated that the abundance of the methoxy-O protonated tautomer of the methyl carbamate will be negligible, since the tautomer is unfavorable thermodynamically as well as kinetically. Fully optimized stationary points are reported.