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Effects of Feeding a Combination of Probiotics Containing Lactobacillus plantarum and Bacillus Subtilis on Immune Response and Diarrhea Incidence in Post-weaning Piglets  

Park, Eun-Kee (Department of Medical Humanities and Social Medicine, College of Medicine, Kosin University)
Yoo, Eun-Ah (Tongyeong National Quarantine Station, Ministry of Health & Welfare)
Cha, Chun-Nam (Department of Industrial Systems Engineering and Engineering Research Institute, College of Engineering, Gyeongsang National University)
Tutkun, Engin (Ankara Occupational Diseases Hospital, Ministry of Health)
Kim, Suk (Research Institute of Live Sciences, College of Veterinary Medicine, Gyeongsang National University)
Lee, Hu-Jang (Research Institute of Live Sciences, College of Veterinary Medicine, Gyeongsang National University)
Publication Information
Journal of Veterinary Clinics / v.30, no.6, 2013 , pp. 459-463 More about this Journal
Abstract
A study investigated the effects of a mixture of Lactobacillus plantarum (L. plantarum) and Bacillus subtilis (B. subtilis) on diarrhea incidence, immune response, and fecal microflora counts in post-weaning piglets. One hundred 28-day-old piglets were randomly assigned to five treatment groups: negative control (NC), free of antibiotics; positive control (PC), 0.03% chlortetracycline; LB 1, a mixture of L. plantarum and B. subtilis (LB) 0.5 kg/ton feed; LB 2, LB 1.0 kg/ton feed; and LB 3, LB 2.0 kg/ton feed. Diarrhea scores for LB 2 and LB 3 from the 2nd week were significantly reduced compared to NC (P<0.05). In terms of the level of IgG and IFN-${\gamma}$, all treatment groups were significantly higher than NC (P<0.05), and the IgG level of LB 3 was significantly higher than that of PC (P<0.05). Furthermore, fecal lactic acid bacteria (LAB) counts for LB 2 and LB 3 were significantly higher than those of NC and PC (P<0.05). In addition, fecal Enterobacteriaceae (ENT) counts for PC, LB 2 and LB 3 were significantly lower than those of NC (P<0.05). Based on the results from this study, it was concluded that a combination of L. plantarum and B. subtilis strains could be used as potential alternatives to antibiotics to prevent diarrhea incidence in piglets.
Keywords
Bacillus subtilis; Lactobacillus plantarum; fecal microflora; diarrhea scores; piglets;
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