• Journal of Embryo Transfer
• /
• v.26 no.2
• /
• pp.129-133
• /
• 2011

Drinking of excessive ethanol during pregnancy induces a fetal alcohol syndrome. Genistein is one of naturally occurring isoflavones at relatively high levels in soybeans. In this study, we investigated the effects of genistein ($1{\times}10^{-8}$ and $1{\times}10^{-7}\;{\mu}g$/ml) on the ethanol (1 ${\mu}l$/ml)-induced teratogenesis of developing mouse embryos during the critical period (embryonic days 8.5~10.5) of organogenesis using a whole embryo culture system and then morphological scoring analysis. Ethanol-treated embryos exhibited a variety of developmental abnormalities. However, the total morphological scores for ethanol plus genistein groups were significantly higher than those of ethanol alone group (p<0.05). In particular, there were significant increases in the ethanol plus $1{\times}10^{-8}\;{\mu}g$/ml of genistein group on the scores for heart, optic system, branchial bar, mandibular process, and caudal neural tube and further in the ethanol plus $1{\times}10^{-7}\;{\mu}g$/ml of genistein group on the scores for heart, hind-, mid-, and forebrains, optic system, branchial bars, maxillary and mandibular processes, caudal neural tube, forelimb, hindlimb, and somites as compared with those of ethanol alone group (p<0.05). These results indicate that genistein has a preventive effect against ethanol-induced teratogenesis.

• The Journal of the Korea Contents Association
• /
• v.13 no.5
• /
• pp.342-353
• /
• 2013

Objectives: It attempted to analyze influencing factors on the utilization of outpatient services which were adopted to predisposing, enabling, and need factors in Anderson model. Methods: The current study analyzed "2007 Korean National Health Nutrition Survey" data, which selected 3,335 people nationwide by proportional systematic sampling. This study analyzed data of persons who used outpatient services in two weeks. It adopted Anderson Model to control contextual factors including socioeconomic factors. The study compared means and fitted logistic regression models and multilevel model. Results: The logistic regression model showed that persons purchased private medical insurance were less likely to use outpatient services than the persons did not purchase private medical insurance. Persons with hypertension and diabetes mellitus, overweight, and problem drinkers were more likely to use outpatient services. Persons with high school graduates or higher in education level and experience of accidents or intoxications were more likely to use outpatient services according to the multilevel analysis of mixed model which treated region as random effect. Conclusion: Higher level of perceived stress increased the probability to use outpatient service than lower level of perceived stress. As number of days a person had exercised increased, the probability to use outpatient service decreased. Overweight and problem alcohol drinking increased the probability of outpatient service use. Further research should be conducted to find more factors influencing outpatient service use.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.19 no.2
• /
• pp.155-163
• /
• 2018

This study was conducted to investigate the factors related to smoking and smoking differences among adolescents who have experienced smoking using data from the 11th (2015) Korean Youth Risk Behavior Web-based Survey. The data used in this study were from 5,347 middle and high school students who had cigarette smoking and electronic cigarette smoking experience among 68,043 respondents to the 11th (2015) Korean Youth Risk Behavior Web-based Survey. The data were evaluated by frequency analysis, the ${\chi}^2$ test and logistic regression analysis using weighted composite sample analysis. Overall 20% of the total smoking adolescents were dual users and 85.6% of the users of electronic cigarettes used nicotine. The results from multinomial regressions show that: male students (OR 1.63; 95% CI 1.15-2.31), living in the metropolitan area (OR 1.76; 95% CI 1.32-2.33), an average consumption of fast food of once or twice a day (OR 2.48; 95% CI 1.33-4.64), first started smoking during high school (OR 0.76; 95% CI 0.58-0.98), having experience with passive smoking (OR 1.24; 95% CI 1.07-1.44), experience drinking alcohol (OR 2.03; 95% CI 1.65-2.48) and those with higher weekly allowances were more likely to be at risk than dual users. This study provides basic data regarding the dual use of electronic cigarettes and cigarettes by adolescents. The results presented herein will facilitate development of a smoking cessation program and policy.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.10 no.4
• /
• pp.707-716
• /
• 2009

The levels of psychosocial stresses and fatigue of firemen were analyzed to reveal the various factors related to them. The self-administered questionnaires were performed to 262 firemen ill Cheonsju City. In terms of various levels of psychosocial stresses, 12.2% were under potential stresses, 87.8% were under high-level of stress, but healthy group was not found. The levels of fatigue symptoms divided by the median of total scores was 51.1% of low levels, and 48.9% of high levels. Multiple stepwise analysis revealed that the factors or influence on psychosocial stresses with explanatory powers of 11.5% included subjective health status, job satisfaction, job demand and alcohol drinking habits. The factors of influence on fatigue symptoms with explanatory powers of 9.0% included subjective health and regular exercises. The study results indicate that the level of stress or fatigue is so complicatedly influenced by variable factors. Thus the effective strategy for stress and fatigue reduction among firemen should include additional programs focusing on health promotion.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.15 no.9
• /
• pp.5610-5620
• /
• 2014

This study was conducted to determine the levels of job stress, as well as its association with psychosocial factors (type A behavior pattern, locus of control, and self-esteem). Self-administered questionnaires were given to 634 clerical public officers in the C Provincial Office between February 18 and Mar. 10, 2013. As a result, the job stress levels of the subjects was significantly different according to age, sex, educational level, marital status, job position, job career, satisfaction in job life, smoking, alcohol drinking, sleeping time, type A behavior pattern, locus of control, and self-esteem. Regarding the correlation of job stress and psychosocial factors, the level of job demand was negatively correlated with the internal locus of control. The decision latitude was negatively correlated with the type A behavior pattern, internal locus of control and self-esteem. Supervisor support was negatively correlated with the external locus of control. In hierarchial multiple regression analysis, the affecting factors to the job stress selected variables, such as age, subjective health status, job position, overtime work, experience of sick absence, satisfaction in work, sleeping time, leisure time, visiting out-patient department, type A behavior pattern, locus of control, and self-esteem, and the explanatory powers of these factors was 32.1%. In particular, the factors related to the psychosocial factors (type A behavior pattern, locus of control, self-esteem) were strongly related to the job stress, increasing the explanation of factors up to 15.0%.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.15 no.6
• /
• pp.3685-3695
• /
• 2014

This study was performed to determine the suicide ideation and its association with hopelessness, psychosocial stress and depression among some middle school students. The survey was administered to 975 middle school students in Gyeongin area during the period, May $1^{st}$ to June $30^{th}$, 2013. Structured self-administered questionnaires were delivered and collected without the respondents' personal information. As a result, concerning the correlation of depression with various factors, the level of suicide ideation was positively correlated with hopelessness, psychosocial stress and depression. Multiple linear regression analysis showed that the factors influencing the suicide ideation included sex distinction, experience of alcohol drinking, hobbies and leisure life, subjective health status, grade, school violence experience, hopelessness, psychosocial stress and depression. An analysis of the covariance structure, hopelessness (BHOP) was more influential on the suicide ideation than psychosocial stress (PWI) and depression (CES-D). The study found that higher hopelessness, severe distress and higher depression tends to increase the suicide ideation.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.14 no.12
• /
• pp.6330-6339
• /
• 2013

The aims of this study were to identify the significant predictors of the sexual behavior of middle school students. The subjects consisted of 603 middle school students (male 344, female 259). The data was collected through self-report questionnaires, which were constructed to include the attitudes to sexual behavior, sexual permissiveness, perceived behavioral control, sexual behavioral intention, father's child-rearing attitudes, mother's child-rearing attitudes, friends' attitudes to sex, exposure to pornography, and sexual behavior. The data was analyzed using the SPSS 19.0 program. The significant predictors of sexual behavior of middle school students that explained 51.0% of the variance in sexual behavior were the friends' attitudes to sex, alcohol drinking experience, experience of sexual abuse, sexual permissiveness, exposure to pornography, sexual behavioral intention, perceived behavioral control, father's child-rearing attitudes, and mother's child-rearing attitudes. These findings suggest that the approach to a sexual education promotion program for middle school students should consider multisystemic predictors.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.16 no.3
• /
• pp.2089-2099
• /
• 2015

This study examined the relationships between the blood heavy metal (Pb, Hg and Cd) concentration and exposure-related factors. The subjects were 2,042 (male: 953, female: 1,089) who were recruited through a National Health and Nutrition Examination Survey. Differences in the concentrations of mercury were observed in males, whereas females showed differences in lead and cadmium. Analyses of the blood concentrations according to body mass index and waist circumference showed significantly higher concentrations of mercury. In males, high-density lipoprotein cholesterol of dyslipidemia was higher than normal in the blood lead concentration. In females, low-density lipoprotein cholesterol of dyslipidemia was higher than normal in the blood lead concentration. The blood lead and cadmium concentrations of male smokers was higher than non-smokers, and cadmium showed the same results in females. The blood lead levels were higher in male alcohol consumers than non-drinkers. The blood concentrations of mercury and cadmium showed significant differences according to household income. Blood concentrations of heavy metals were closely related to exposure-related factors, and age, smoking, drinking alcohols, obesity, hyperlipidemia, and household income were found to be relevant.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.18 no.5
• /
• pp.268-277
• /
• 2017

This study was performed to determine the level of physical health(ADL, IADL) and mental health (cognitive impairment, dementia) among centenarians and to find the related factors. The study subjects were 268 centenarians who received medical check-ups from the National Health Insurance Corporation during 2011-2014. From the results, the factors that significantly influenced the ADL of the study subjects were gender, residential area, IADL, cognitive impairment and dementia. ADL and cognitive impairment were selected as the influencing factors of IADL, smoking status, ADL and IADL were selected as the influencing factors of cognitive impairment, and gender and ADL were selected as the influencing factors of dementia. These results suggested that the levels of physical and mental health of the centenarians were significantly affected by socio-demographic characteristics and health-related variables. Especially, the levels of physical and mental health were decreased with the poor group of health-related variables such as smoking, alcohol drinking and regular exercise.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.19 no.4
• /
• pp.423-432
• /
• 2018

The purpose of this study was to provide basic data to promote health in middle-aged Koreans (40-59 years old) by understanding health behaviors that affect high-density lipoprotein (HDL) cholesterol level among various health behaviors. In a national health and nutrition survey, raw data combined on a total of 7,406 persons, IV-3 (2009), V-1 (2010), V-2 (2011), V-3 (2012), and VI-1 (2013), were selected as the final analysis subjects. HDL cholesterol was divided into two groups: less than 40 mg/dl and more than 40 mg/dl. The results of multiple logistic regression analysis were as follows: OR=3.916 for males, OR=3.439 for normal than low weight, OR=7.336 for obesity than low weight, OR=1.629 for alcohol consumption, OR=1.498 for smokers, OR=1.426 for don't practice moderate physical activity, OR=1.264 for no walking exercise, OR=1.510 for carbohydrates normal intake than low intake, OR 1.787 for carbohydrates over intake than low intake when HDL cholesterol increased from 40 mg/dl to less than 40 mg/dl. Korean middle-aged high-density lipoprotein (HDL) cholesterol levels should be increased to maintain proper health through aerobic exercise, smoking cessation, proper drinking habits, obesity relief, healthy eating out, and healthy food choices. This requires continuous publicity and education within the community, and a social environment should be built that enables health behavior to be practiced in daily life.