• Tuberculosis and Respiratory Diseases
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• v.39 no.2
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• pp.141-149
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• 1992

In order to establish predicted normal values of volume of isoflow($V_{iso}\dot{V}$), $V_{iso}\dot{V}$ were measured in a total 234 healthy adults, consisting of 78 male nonsmokers, 108 male smokers and 48 female nonsmokers. The volumes of isoflow were determined through analysis of maximal expiratory flow volume curves recorded with a mixture of 80% helium and 20% oxygen(He-$O_2$ gas) following one(1VC) and three vital capacity(3VC) maneuver and with room air. Based upon the correlation of the observed values of the parameters to age and physical characteristics, the following regression formulars for the prediction of the parameters, using age in year(A) as a variable, were obtained. 1VC method ($V_{iso}\dot{V}_1$) Male smoker : 0.614A+2.347 Male nonsmoker : 0.370A-2.792 Female nonsmoker : 0.588A-2.459 3VC method ($V_{iso}\dot{V}_3$) Male smoker : 0.467A+1.696 Male nonsmoker : 0.288A-1.538 Female nonsmoker : 0.367A-0.114.

• BMB Reports
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• v.48 no.3
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• pp.153-158
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• 2015

As FK506 binding proteins (FK506BPs) are known to play an important role in the regulation of a variety of biological processes related to cell survival, this study was designed to examined the protective effects of FK506 binding protein 12 (FK506BP) on low humidity air flow induced dry eye in a rat model using transduced PEP-1-FK506BP. After the topical application of PEP-1-FK506BP, tear volumes were markedly increased and significant prevention of cornea damage was observed compared with dry eye rats. Further, immunohistochemical analysis demonstrated that PEP-1-FK506BP markedly prevented damage to the cornea, the bulbar conjunctiva, and the palpebral conjunctiva epithelial lining compared with dry eye rats. In addition, caspase-3 and PARP expression levels were found to be decreased. These results demonstrated that topical application of PEP-1-FK506BP significantly ameliorates dry eye injury in an animal model. Thus, we suggest that PEP-1-FK506BP can be developed as a new ophthalmic drop to treat dry eye diseases.

• Journal of Advanced Marine Engineering and Technology
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• v.35 no.8
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• pp.1055-1062
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• 2011

The purpose of this study is to develop the shape of photocatalyst-coated module for improve the IAQ, which is installed at inside of ductwork and detachable. Including 3 column types(square, circle, diamond) and 2 fin types(diamond and square), totally 5 types are previously declared for numerical analysis and comparison, 5 types are. As the results of numerical analysis, almost the velocity varied at the range of ${\pm}0.3m$ from the module, except the Type A-3(diamond column type) which is affected to ${\pm}0.4m$ range and shows the biggest velocity differences. Among the 5 types, the diamond fin type(Type B-1) is analyzed as the most stable in velocity. And the results of local pressure drop show that the difference of pressure coefficient of Type B-1 is computed as 0.59, and that of Type A-3 is 2.44. Meanwhile, from the effect analysis of the number of module, the flow conflict happens and the pressure difference between before and after the module increases if there are over 3 modules inserted.

• Korean Journal of Environmental Agriculture
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• v.20 no.4
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• pp.238-243
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• 2001

Mass reduction and physicochemical properties of the produced compost were investigated during composting domestic food wastes without additive. A small composter used in this study had the height of 15 cm from the center of bottom half circle (diameter 24 cm) up to under the lid, the side length of 50 cm and the horizontal lid angle of $50^{\circ}$ and was operated at the heating unit temperature of $85^{\circ}$. It was mixed by the rotating arm for two minutes in every half hour while supplied with air flow at 3 L/min for 10 minutes in every half hour. This condition was found in a preliminary experiment as optimal for keeping the water content of composting material in the optimal range without adding any bulking materials. The domestic food wastes were added into the composter at the rate of 1 kg/day without additives during composting. The results were as follows; during the composting process, water content maintained in the range of $51.0{\sim}53.5%$. Hemicellulose and lignin contents did not show any tendency, but cellulose content decreased. During the composting process, $NH_3-N$ and $NO_2-N$ were not detected due to nitrification. The contents of inorganic compounds did not increase during the composting process. They were in the range of $1.32{\sim}1.71%\;P_2O_5$, $1.29{\sim}1.48%\;CaO$, $0.41{\sim}0.49%\;MgO$, and $0.38{\sim}0.74%\;K_2O$. For 20 days, weight reduction rate was 67.5% in wet basis, and decomposition rate was 48% in dry basis. Concentration of heavy metals (Cu, Cr, Cd, Pb, Zn, Hg, As) was less than the limiting value of the compost. Maturity of the produced compost was 3 grade through reaching maximum temperature of $46{\sim}48^{\circ}C$.

• Journal of Bio-Environment Control
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• v.25 no.2
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• pp.123-132
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• 2016

The importance of energy saving technology for managing greenhouse was recently highlighted. For practical use of energy in greenhouse, it is necessary to simulate energy flow precisely and estimate heating/cooling loads of greenhouse. So the main purpose of this study was to develope and to validate greenhouse energy model and to estimate annual/maximum energy loads using Building Energy Simulation (BES). Field experiments were carried out in a multi-span plastic-film greenhouse in Jeju Island ($33.2^{\circ}N$, $126.3^{\circ}E$) for 2 months. To develop energy model of the greenhouse, a set of sensors was used to measure the greenhouse microclimate such as air temperature, humidity, leaf temperature, solar radiation, carbon dioxide concentration and so on. Moreover, characteristic length of plant leaf, leaf area index and diffuse non-interceptance were utilized to calculate sensible and latent heat exchange of plant. The internal temperature of greenhouse was compared to validate the greenhouse energy model. Developed model provided a good estimation for the internal temperature throughout the experiments period (coefficients of determination > 0.85, index of agreement > 0.92). After the model validation, we used last 10 years weather data to calculate energy loads of greenhouse according to growth stage of greenhouse crop. The tendency of heating/cooling loads change was depends on external weather condition and optimal temperature for growing crops at each stage. In addition, maximum heating/cooling loads of reference greenhouse were estimated to 644,014 and $756,456kJ{\cdot}hr^{-1}$, respectively.

• Korean Journal of Soil Science and Fertilizer
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• v.36 no.4
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• pp.181-192
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• 2003

We developed a mathematical simulation model to portray the vertical distribution of soil water from the measured weather data and the known soil hydraulic properties, and then compared simulation results with the periodically measured soil water profiles obtained on Jungdong sandy loam to verify the model, In this model, we solved potential-based Richards' equation by the implicit finite difference method superimposed on the predictor-corrector scheme. We presumed that: soil hydraulic properties are homogeneous; soil water flows isothermally; hysteresis is not considered; no vapor flows; no heat transfers into the soil profiles; and water added to soil surface is distributed along the soil profile following partial displacement principle. The input data were broadly classified into two groups: (1) daily weather data such as rainfall, maximum and minimum air temperatures, relative humidity and solar radiation and (2) soil hydraulic data to approximate unsaturated hydraulic conductivity and water retention. Each hydraulic polynomial function approximated using the Chebyshev polynomial and least square difference technique in tandem showed a fairly good fit of the given set of data. Vertical distribution of soil water as approximations to the Richards' equation subject to changing surface and phreatic boundaries was solved numerically during 53 days with a comparatively large time increment, and this pattern agreed well with field neutron scattering data, except for the surface 0.1 m slab.

• Journal of the Korean Geographical Society
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• v.36 no.2
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• pp.126-140
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• 2001

The influence of small urban parks(green ratio is 100%) on the temperature pattern over the urban and its surrounding area was examined by analyzing the case of in and around Changkyeong palace, Changdeok plalace and Jongmyo, Jongro-gu, Seoul. The pattern of temperature over urban parks and their surrounding built-up area was analyzed from September to November 2000, measuring maximum and minimum temperatures with fixed sensors(maximum and minimum thermometer)and real-time temperature depends largely on both the land-use type and the distance from the park border. In the case of maximum temperature, the lowest value appeared on the green area within parks and the highest value on the built-up area far from the green area. The maximum temperature difference between parks and built-up areas was up to $7.3^{\circ}C$. In the built-up area, the maximum temperature of commercial areas was higher than residential areas. In the night time, not only land-use type but also topography is important for the spatial distributlon of temperature because of the cold airflow from adjacet hills. The horizontal temperature profile by mobile measurement is also related to land-use type and to the distance from the park borders. There is a magnitude of $1^{\circ}C$ temperture difference over a distance of 200m and $3~4^{\circ}C$ over a distance of 400m from the park borders.

• Proceedings of the Korean Society of Near Infrared Spectroscopy Conference
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• 2001.06a
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• pp.3104-3104
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• 2001

The research described here was undertaken with the aim of monitoring, optimizing and ultimately controlling the production of heterofermentative microbes used as starters in the salami industry. The use of starter cultures in the fermented meats industry is a well-established technique used to shorten and standardize the ripening process, and to improve and control the organoleptic quality of the final product. Starter cultures are obtained by the submerged cultivation of suitable microorganisms in stirred, and sometimes aerated, fermenters where monitoring of key physiological parameters such as the concentration of biomass, substrates and metabolites suffers from the general lack of real-time measurement techniques applicable to aseptic processes. In this respect, the results of the present work are relevant to all submerged fermentation processes. Previous work on the application of on-line NIR spectroscopy to the lactic acid fermentation (Dosi et al. - Monreal NIR1995) had successfully used a system based on a measuring cell included in a circulation loop external to the fermenter. The fluid handling and sterility problems inherent in an external circulation system prompted us to explore the use of an in-line system where the NIR probe is immersed in the culture and is thus exposed to the hydrodynamic conditions of the stirred and aerated fluid. Aeration was expected to be a potential source of problems in view of the possible interference of air bubbles with the measurement device. The experimental set-up was based on an in-situ sterilizable NIR probe connected to the instrument by means of an optical fiber bundle. Preliminary work was carried out to identify and control potential interferences with the measurement, in particular the varying hydrodynamic conditions prevailing at the probe tip. We were successful in defining the operating conditions of the fermenter and the geometrical parameters of the probe (flow path, positioning, etc.) were the NIR readings were reliable and reproducible. The system thus defined was then used to construct and validate calibration curves for tile concentration of biomass, carbon source and major metabolites of two different microorganisms used as salami starters. Real-time measurement of such parameters coupled with the direct interfacing of the NIR instrument with the PC-based measurement and control system of the fermenter enabled the development of automated strategies for the interactive optimization of the starter production process.

• Proceedings of the Korean Society of Near Infrared Spectroscopy Conference
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• 2001.06a
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• pp.1273-1273
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• 2001

The efficiency of the luminal fermentation process influences overall efficiency of luminal production, animal health and reproduction. Ruminant production systems have a significant impact on the global environment, as well. Animal wastes contribute to pollution of the environment as ammonia volatilized to the air and nitrate leached to ground water. Microbial protein synthesis in the rumen satisfies a large proportion of the protein requirements of animals. Quantifying the microbial synthesis is possible by using markers for lumen bacteria and protozoa such as nucleic acids, purine bases, some specific amino acids, or by isotopic $^{15}N,^{32}P,\;and\;^{35}S$ labelled feeds. All those methods require cannulated animals, they are time-consuming and some methods are very expensive as well. Many attempts have been made to find an alternative method for indirect measurement of microbial synthesis in intact animals. The present investigations aimed to assess possibilities of NIRS for prediction of purine nitrogen excretion and ruminal microbial nitrogen synthesis by NIR spectra of urine. Urine samples were collected from 12 growing sheep,6 of them male, and 6- female. The sheep were included in feeding experiment. The ration consisted of sorghum silage and protein supplements -70:30 on dry matter basis. The protein supplements were chosen to differ in protein degradability. The urine samples were collected daily in a vessel containing $60m{\ell}$ 10% sulphuric acid to reduce pH below 3 and diluted with tap water to 4 liters. Samples were stored in plastic bottles and frozen at $-20^{\circ}C$ until chemical and NIRS analysis. The urine samples were analyzed for purine derivates - allantoin, uric acid, xantine and hypoxantine content. Microbial nitrogen synthesis in the lumen was calculated according to Chen and Gomes, 1995. Transmittance urine spectra with sample thickness 1mm were obtained by NIR System 6500 spectrophotometer in the spectral range 1100-2500nm. The calibration was performed using ISI software and PLS regression, respectively. The following statistical results of NIRS calibration for prediction of purine derivatives and microbial protein synthesis were obtained.(Table Omitted). The result of estimation of purine nitrogen excretion and microbial protein synthesis by NIR spectra of urine showed accuracy, adequate for rapid evaluation of microbial protein synthesis for a large number of animals and different diets. The results indicate that the advantages of the NIRS technology can be extended into animal physiological studies. The fast and low cost NIRS analyses could be used with no significant loss of accuracy when microbial protein synthesis in the lumen and the microbial protein flow in the duodenum are to be assessed by NIRS.

• Atmosphere
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• v.22 no.1
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• pp.29-45
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• 2012

An unusual autumn storm developed rapidly in the western part of the East sea on the early morning of 23 October 2006. This storm produced a record-breaking heavy rain and strong wind in the northern and middle part of the Yeong-dong region; 24-h rainfall of 304 mm over Gangneung and wind speed exceeding 63.7 m $s^{-1}$ over Sokcho. In this study, MTSAT-1R (Multi-fuctional Transport Satellite) water vapor and infrared channel imagery are examined to find out some features which are dynamically associated with the development of the storm. These features may be the precursor signals of the rapidly developing storm and can be employed for very short range forecast and nowcasting of severe storm. The satellite features are summarized: 1) MTSAT-1R Water Vapor imagery exhibited that distinct dark region develops over the Yellow sea at about 12 hours before the occurrence of maximum rainfall about 1100 KST on 23 October 2006. After then, it changes gradually into dry intrusion. This dark region in the water vapor image is closely related with the positive anomaly in 500 hPa Potential Vorticity field. 2) In the Infrared imagery, low stratus (brightness temperature: $0{\sim}5^{\circ}C$) develops from near Bo-Hai bay and Shanfung peninsula and then dissipates partially on the western coast of Korean peninsula. These features are found at 10~12 hours before the maximum rainfall occurrence, which are associated with the cold and warm advection in the lower troposphere. 3) The IR imagery reveals that two convective cloud cells (brightness temperature below $-50^{\circ}C$) merge each other and after merging it grows up rapidly over the western part of East sea at about 5 hours before the maximum rainfall occurrence. These features remind that there must be the upward flow in the upper troposphere and the low-layer convergence over the same region of East sea. The time of maximum growth of the convective cloud agrees well with the time of the maximum rainfall.