• Title/Summary/Keyword: AiiA

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The Photoreceptor Populations in the Retina of the Greater Horseshoe Bat Rhinolophus ferrumequinum

  • Kim, Tae-Jin;Jeon, Young-Ki;Lee, Jea-Young;Lee, Eun-Shil;Jeon, Chang-Jin
    • Molecules and Cells
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    • v.26 no.4
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    • pp.373-379
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    • 2008
  • Recently, we reported the existence of AII "rod" amacrine cells in the retina of the greater horseshoe bat Rhinolophus ferrumequinum (Jeon et al., 2007). In order to enhance our understanding of bat vision, in the present study, we report on a quantitative analysis of cone and rod photoreceptors. The average cone density was $9,535cells/mm^2$, giving a total number of cones of 33,538 cells/retina. The average rod density was $368,891cells/mm^2$, giving a total number of rods of 1,303,517 cells. On average, the total populations of rods were 97.49%, and cones were 2.51% of all the photoreceptors. Rod: cone ratios ranged from 33.85:1 centrally to 42.26:1 peripherally, with a mean ratio of 38.96:1. The average regularity index of the cone mosaic in bat retina was 3.04. The present results confirm the greater horseshoe bat retina to be strongly rod-dominated. The rod-dominated retina, with the existence of AII cells discovered in our previous study, strongly suggests that the greater horseshoe bat retina has a functional scotopic property of vision. However, the existence of cone cells also suggests that the bat retina has a functional photopic property of vision.

Calretinin-Immunoreactive Amacrine Cells and Ganglion Cells in the Greater Horseshoe Bat, Rhinolophus ferrumequinum (한국관박쥐망막에서 칼레티닌 면역반응성의 무축삭세포 및 신경절 세포에서의 관찰)

  • Jeon, Young-Ki;Jeon, Chang-Jin
    • Journal of Korean Ophthalmic Optics Society
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    • v.12 no.4
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    • pp.133-139
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    • 2007
  • Although the physiological roles of calretinin have not been established, it may simply work as a calcium buffer or may actively work in calcium-mediated signal transduction. Calretinin plays a little role in the transport and physiological buffering of calcium in the adult photoreceptor cells, bipolar cells and horizontal cells of the human retina. We identified the calretinin-immunoreactive neurons in the inner nuclear cell layer and ganglion cell layer and the distribution pattern of the labeled neurons in the retina of a bat, Rhinolophus ferrumequinum, in this study. We observed the existence of calretinin-immunoreactive AII amacrine cell in the inner nuclear layer and ganglion cells in the ganglion cell layer of bat retina through this study. This observation must be significant along with our previous studies as we need to study for more understanding about the unsolved issue of a bat vision and the unique behavioral aspects of bat flight maneuverability.

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Comparative Evaluation of Measures against the Spread of Air-borne Infections in a Large National Hospital and Small and Medium-sized Clinics in Korea (국내 대형병원과 중·소규모 의원의 공기감염 확산 방지 대책의 비교 평가)

  • An, Jiwon;Yang, Young Kwon;Won, An-Na;Hwang, Jung Ha;Park, Jin Chul
    • Journal of Korean Living Environment System
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    • v.25 no.1
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    • pp.90-97
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    • 2018
  • The purpose of this study is to compare and analyze the air infections in middle and small hospitals with the facilities of large national hospitals that have air-borne infection isolation (AII) wards through actual condition investigation and airflow analysis simulation (CFD) and to provide basic data for prevention. The method and scope of the study are as follows. First, through literature review, data related to prevention of infection spread in domestic medical institutions were investigated. Second, we conducted a survey on the status of isolation facilities to prevent the spread of infectious diseases in large hospitals and small and medium - sized clinics in Korea. Third, airflow analysis simulation (CFD) was carried out using the isolation ward of the nationally designated inpatient ward and the data of the plane and facility system of the small clinic. As a result of the study, it is found that regulations applicable to small and medium-sized clinics are insufficient. In addition, the simulation results show that the infectious disease virus is likely to spread to other patients in the hospital.

3D-QSAR on the Herbicidal Activities of New 2-(4-(6-chloro-2-benzoxazolyloxy)phenoxy)-N-phenylpropionamide Derivatives (새로운 2-(4-(6-chloro-2-benzoxazolyloxy)phenoxy)-N-phenylpropionamide 유도체들의 제초활성에 관한 3차원적인 정량적 구조와 활성과의 관계)

  • Sung, Nack-Do;Jung, Hoon-Sung
    • Applied Biological Chemistry
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    • v.48 no.3
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    • pp.252-257
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    • 2005
  • Three-dimensional quantitative structure-activity relationships (3D-QSARs) for the herbicidal activities against pre-emergence barnyard grass (Echinochloa crus-galli) by new 2-(4-(6-chloro-2-benzoxazolyloxy)phenoxy)-N-phenylpropion amide derivatives were studied quantitatively using comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) methodologies. The best CoMFA model (AI-2) and CoMSIA model (AII-4) were derived from an atom based fit alignment and a combination of CoMFA fields. The herbicidal activities from CoMFA and CoMSIA contour maps showed that the activity will be able to be increased according to the substituents variation on the N-phenyl ring.

Hall Effect on Unsteady Couette Flow. with Heat Transfer Under Exponential Decaying Pressure Gradient

  • Attia HazemAIi
    • Journal of Mechanical Science and Technology
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    • v.19 no.11
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    • pp.2053-2060
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    • 2005
  • The unsteady Couette flow of an electrically conducting, V1SCOUS, incompressible fluid bounded by two parallel non-conducting porous plates is studied with heat transfer taking the Hall effect into consideration. An external uniform magnetic field and a uniform suction and injection are applied perpendicular to the plates while the fluid motion is subjected to an exponential decaying pressure gradient. The two plates are kept at different but constant temperatures while the Joule and viscous dissipations are included in the energy equation. The effect of the ion slip and the uniform suction and injection on both the velocity and temperature distributions is examined.

Nonstructural Protein 5B of Hepatitis C Virus

  • Lee, Jong-Ho;Nam, In Young;Myung, Heejoon
    • Molecules and Cells
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    • v.21 no.3
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    • pp.330-336
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    • 2006
  • Since its identification in 1989, hepatitis C virus has been the subject of extensive research. The biology of the virus and the development of antiviral drugs are closely related. The RNA polymerase activity of nonstructural protein 5B was first demonstrated in 1996. NS5B is believed to localize to the perinuclear region, forming a replicase complex with other viral proteins. It has a typical polymerase structure with thumb, palm, and finger domains encircling the active site. A de novo replication initiation mechanism has been suggested. To date, many small molecule inhibitors are known including nucleoside analogues, non-nucleoside analogues, and pyrophosphate mimics. NS5B interacts with other viral proteins such as core, NS3, 4A, 4B, and 5A. The helicase activity of NS3 seems necessary for RNA strand unwinding during replication, with other nonstructural proteins performing modulatory roles. Cellular proteins interacting with NS5B include VAMP-associated proteins, heIF4AII, hPLIC1, nucleolin, PRK2, ${\alpha}$-actinin, and p68 helicase. The interactions of NS5B with these proteins might play roles in cellular trafficking, signal transduction, and RNA polymerization, as well as the regulation of replication/translation processes.

An Efficient Construction of Chor-Rivest Knapsack Cryptosystem (Knapsack 공개키 암호법의 효율적인 구현)

  • 김세헌
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.1 no.1
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    • pp.16-28
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    • 1991
  • Knapsack public-key cryptosystems are based on the knapsack problem which is NP-complete. aii of the knapsack problem, are known to be insecure. However, the Chor and Rivest knapsack cryptosystem based on arithmetic in finite field is secure against all known cryptosystem based on arithmetic in a finite field is secure against all known cryptanalytic attacks. We suggest a new msthod of attack on knapsack cryptosystem which is based on the relaxation of a quadratic 0-1 integer optimization problem. We show that under certain condirions some bits of the solution of knapsack problem can be determined by using persistency property of linear relaxation. Also we propose a new Chor-Rivest system, this new cryptosystem reduces the number of calculation of discrete logarithms which are necessary for the implemention in a multi-user system.

Effects of Exercise Periods of Aerobic Dance on the Serum HDL-Cholesterol in Middle - Aged Women (중년여성의 에어로빅댄스의 수행기간이 혈청 HDL-Cholesterol에 미치는 영향)

  • 안창순
    • The Korean Journal of Food And Nutrition
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    • v.5 no.2
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    • pp.123-131
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    • 1992
  • This study was designed to find out the effects of aerobic exercise on the serum lipids in the middle-aged women. The effects of aerobic dancing on serum total cholesterol(TC), triglyceride(TG) and HDL-cholesterol (HDL-C) were studied in eight sedentary women(control group) and twenty seven aerobic exercising women(aerobic group) , aged 35∼45%. Aerobic exercising subjects were divided into 3 group; 2 to 3 months exercising group(Al), 4 to 10 months exercising group(AH), over 1 year exercising group(AIII) according to the periods of exercise. The serum lipid levels of aerobic exercising groups(AI, AII, AIIII) were compared with those of control group. The results statistically analyzed were summarized as follows : 1) The serum TG levels of aerobic groups decreased very significantly compared with those of control group(p< 0.001) and tended to be lower with the increase in aerobic periods. But there were no significant differences among aerobic groups by ANOVA. 2) The serum TC levels of aerobic groups decreased compared with those of control group and tended to be lower with the increase of aerobic periods. But there were no significant differences among groups. 3) Serum HDL-cholestrol level of A I group was elevated significantly compared with that of control group and significant difference was observed according to the aerobic periods : AR group exhibited higher serum HDL-cholesterol values than AH group, and AH group higher than A I group.

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Microstructure Characteristics and Electrical Properties of Sintered $(Bi,La)_4Ti_3O_{12}$ Ferroelectric Ceramics (소결한 $(Bi,La)_4Ti_3O_{12}$ 강유전체 세라믹의 미세구조 및 전기적 특성)

  • Yoo, Hyo-Sun;Son, Yong-Ho;Ur, Soon-Chul;Ryu, Sung-Lim;Kweon, Soon-Yong
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2006.06a
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    • pp.276-277
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    • 2006
  • 1mm-thick BLT ceramics were sintered in accordance with a bulk ceramic fabrication process. AII XRD peaks detected in the sintered ceramics were indexed as the Bi-layered perovskite structure without secondary phases. Density was increased with increasing the sintering temperature up to $1050^{\circ}C$ and the maximum value was about 98% of the theoretical density. The remanent polarization (2Pr) value of BLT ceramic sintered at $1050^{\circ}C$ was approximately $6.5\;{\mu}C/cm^2$ at the applied voltage of 4.5 kV. The calculated electromechanical coupling factor ($k_t$) of it was about 5% and the mechanical quality factor (Qm) was about 2200. From these results, a BLT ceramic target for pulsed laser deposition (PLD) system was successfully fabricated.

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