• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2009년도 학술발표회 초록집
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• pp.2190-2199
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• 2009

Nihombashi is located in the central area of Tokyo, Japan. Tokyo has been the capital in Japan since the Edo period, which started approximately 400 years ago, and has accepted a variety of cultures, human resources, businesses for the last 400 years. This has resulted in building up the present prosperity. The Sumida River, one of the symbols of Tokyo and its tributaries including the Kanda River and the Nihombashi River, flows through the Nihombashi district. The river and tributaries used to benefit to the City of Edo. Due to the economic development and the industrial growth in Tokyo, however, they were polluted and lost their functions. In 1960s, approximately 40 years ago, the Sumida River became so dirty that local citizens kept away from it. The Nihombashi River was covered with an expressway, which was obscuring the river view. Since 1970s, local communities have proposed to rehabilitate rivers in Tokyo successively, and have proceeded with measures for river floods, improvement of sewage systems and construction of water purification facilities. Consequently, the quality of the river water was considerably improved in 1990. The stagnant rivers were turned into ones that local citizens were physically able to come close by. Today, restoring of the environment and the appearance of the city in the old days, Nihombashi district has been proposed as a model city of the future, which is alive with history and culture and harmonizing with rivers. The concept is "To Create, To Reserve, To Restore." This paper introduces a case study of the urban development, in which the local communities and public authorities collaborated with and proposed a brand-new style of the urban city harmonizing with the environment.

• Archives of Plastic Surgery
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• 제36권3호
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• pp.341-343
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• 2009

Purpose: Morel - Lavallee lesions is post - traumatic effusion at subcutaneous layer. Early management of Morel - Lavallee lesion is percutaneous drainage and compression. Surgical excision is recommended for cases that are chronic. Method: 41 - year old male patient had slow growing, painful mass on left thigh, which has been present for 3 years. He had a history of blunt trauma 3 years ago. Computed tomography presented $10{\times}10{\times}5cm$ sized cystic mass on left thigh, between subcutaneous fat layer and muscle fascia layer. The mass was surgically removed and biopsy was performed. Result: Histopathological examination shows chronic inflammation and fibrotic change. After 6 month follow - up period, postoperative course was uneventful. Conclusion: We performed surgical excision of Morel - Lavalle lesion in a patient who had trauma 3 years ago. We report a case of Morel - Lavallee lesion with the review of the literatures.

• BMB Reports
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• 제49권3호
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• pp.135-136
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• 2016

Small interfering RNAs (siRNAs) have been developed to intentionally repress a specific gene expression by directing RNA-induced silencing complex (RISC), mimicking the endogenous gene silencer, microRNAs (miRNAs). Although siRNA is designed to be perfectly complementary to an intended target mRNA, it also suppresses hundreds of off-targets by the way that miRNAs recognize targets. Until now, there is no efficient way to avoid such off-target repression, although the mode of miRNA-like interaction has been proposed. Rationally based on the model called "transitional nucleation" which pre-requires base-pairs from position 2 to the pivot (position 6) with targets, we developed a simple chemical modification which completely eliminates miRNA-like off-target repression (0%), achieved by substituting a nucleotide in pivot with abasic spacers (dSpacer or C3 spacer), which potentially destabilize the transitional nucleation. Furthermore, by alleviating steric hindrance in the complex with Argonaute (Ago), abasic pivot substitution also preserves near-perfect on-target activity (∼80-100%). Abasic pivot substitution offers a general means of harnessing target specificity of siRNAs to experimental and clinical applications where misleading and deleterious phenotypes from off-target repression must be considered.

• Journal of Chest Surgery
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• 제29권1호
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• pp.115-119
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• 1996

방사선 치료 후 발생한 악성 섬유성 조직구종은 아주 드물며 일반적으로 예후가 나쁘다. 52세 남자환자가 6개월 전부터 발견된 흉골부위에 발생한 동통성의 종괴을 주소로 입원하였다. 환자는 5년전 식도암으로 방사선 치료를 받은 병력이 있었다. 종괴는 절개생검상 흥골육종으로 진단되어 항암약물요법을 5회 시행하였으나, 종괴가 점점 커져 수술을 시행하였다. 수술은 흥골을 덮고있는 피부와 늑연골을 포함하여 흥골 전절제술을 시행하였고 이로 인한 결손부위는 자가늑골 이식, 양측 대흥근 근육판과 피부이식으로 흥벽재건술을 시행하였다. 수술후 조직소견은 악성 섬유성 조직구종에 일치하였다. 수술후 경과는 순조로왔으며 36일째에 퇴원하였다.

• 한국식생활문화학회지
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• 제28권2호
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• pp.115-124
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• 2013

This article examines the types and cooking methods of Suksilkwa as recorded in 14 royal palace studies and 10 old literature texts of the Joseon dynasty (1392-1909). The types of Suksilkwa during the Joseon dynasty were Joran (棗卵), Yulran (栗卵), and Gangran (薑卵). The frequency of the Suksilkwa types during the Joseon dynasty in order were: Gangran (35.4%), Joran (32.3%), and Yulran (32.3%). Prior to 185 years ago, "Junghae-Jungraeeuigwe (丁亥整禮儀軌)" (1827), Joran (棗卵), Yulran (栗卵), and Gangran (薑卵) were called Samsaegran (三色卵). Nearly 144 years ago, "Mujin-Jinchaneuigwe (戊辰進饌儀軌)" (1868) recalled sulsilgwa (熟實果). "Imjin-Jinchaneuigwe (壬辰進饌儀軌)" (1892) first recalled assorted-sulsilgwa (各色熟實果), in which sansabyeong were added in the sulsilgwa. "Sinchuk-Jinyeoneuigwe (辛丑進宴儀軌)" (July 1901), "Imin-Jinchaneuigwe (壬寅進饌儀軌)" (April 1902), "Imin-Jinyeoneuigwe (壬寅進宴儀軌)" (November 1902) described assorted-sulsilgwa (各色熟實果) in which ohmijabyeong were added to the sulsilgwa. Further study will be conducted on recipes and ingredients recorded in these Euigwe and old books in order to develop a standardized recipe to make Suksilkwa appealing to a global palate.

• 한국컴퓨터정보학회논문지
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• 제4권2호
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• pp.155-163
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• 1999

This study is intended to analyze what trend the EVA technique recently actively studied shows according to the financial structure of the firm. As a result of analysis, it was found that the firm with the entire sum of its capitals depleted showed the negative value in both the EVA on the basis of operating profit and the EVA on the basis of cash flow from 5 years before its capitals were depleted. Especially, its EVA showed the negative value more strongly than the cash flow accruing by business activity. In analyzing the EVA of the firm with more than 1,500% of the debt to equity ratio, its EVA also showed the negative value from 5 years ago. But the firm with the good financial structure of the debt to equity of less than 35% showed the positive value in the EVA on the basis of its cash flow from 5 years ago. As can be seen from this result, the fact is that the firm can survive only when it raises its EVA through its structural change(re-engineering) and business innovation. Therefore, firms need to seek to turn their business philosophy or policy into the promotion of business innovation and business management emphasizing technology in order to improve their EVA indicators.

• 한국주거학회:학술대회논문집
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• 한국주거학회 1991년도 학술발표대회논문집
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• pp.19-28
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• 1991

The present state of possesion of durable consumer's goods in on family in Korean is could be similar with that of about 25 years ago in Japan. Korea meet a period of high rate of economic growth, Japan had already experienced this 25 years ago. It would be important to predict and plan the storage space in the planning house since purchase of durable consummers' goods increase greatly as the rapid economic growth. In order to grasp the dweller's way of thinking and an attitude of living in small size house in Japan, questionaire owe prepared focusing on the "small space", possession of excess living goods and dweller's state of living. From the analysis of the answers for questionaire, the result is as follows. (1) Most of dweller's conclude that the reason of the disorder in their house is that their house in too small, so that they think the part of thier living goods must be disposed. This concept is also available even when they buy new living goods. (2) Disposal of living goods not in use, restraint of buying those are considered inevitable. In addition, changing of place of furnitures is also introduced. (3) The dweller living under 50m2 area dosen's not consider the disorder the house by the living goods. they have interest in how the tradition could be kept their home.

• 동의신경정신과학회지
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• 제8권1호
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• pp.141-150
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• 1997

A clinic study was carried out on 83 neuropsychiatric outpatients who visited 'Hwabyung Clinic' in Oriental Hospital of Kyung Hee University from July 1 in 1996, in order to study clinical research and the aspect of 'Hwa'. 1. Onset of stress that causes of Hwabyung was 14.23 years ago and onset of symptoms were 6.39 years ago. Hwabyung patients were maintaining their marital state and were under the same stress that was thought to be the chief causes of the Hwabyung..3. Familiar troubles including their spouse were the main cause of the Hwabyung, which suggested that prolonged trobles were more important rather than sudden emotional shock, and it was obvious that the patients were recognizing the predisposing factors of Hwabyung.5. The emotional state which led to Hwabyung and the present state caused by Heabyung were complicated very much. Feeling being mortified, anger and resentment were gradually changed into anxiety, irritability, depression and loss of interest.6. The somatic symptoms of Hwabyung were flushing, insomnia, hradache, dizziness, and oppressed.7. The feeling of flushing were whole body, front of the body and upper of the body.

• Molecules and Cells
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• 제39권8호
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• pp.581-586
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• 2016

Post-translational modifications (PTMs) of proteins are essential to increase the functional diversity of the proteome. By adding chemical groups to proteins, or degrading entire proteins by phosphorylation, glycosylation, ubiquitination, neddylation, acetylation, lipidation, and proteolysis, the complexity of the proteome increases, and this then influences most biological processes. Although small RNAs are crucial regulatory elements for gene expression in most eukaryotes, PTMs of small RNA microprocessor and RNA silencing components have not been extensively investigated in plants. To date, several studies have shown that the proteolytic regulation of AGOs is important for host-pathogen interactions. DRB4 is regulated by the ubiquitin-proteasome system, and the degradation of HYL1 is modulated by a de-etiolation repressor, COP1, and an unknown cytoplasmic protease. Here, we discuss current findings on the PTMs of microprocessor and RNA silencing components in plants.

• 한국지구물리탐사학회:학술대회논문집
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• 한국지구물리탐사학회 2006년도 공동학술대회 논문집
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• pp.277-280
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• 2006

다수의 공업단지가 갯벌을 매워 조성된 간척지 위에 건설되었다. 공업단지들이 이렇듯 연약한 지반 위에 있기 때문에 지반침하에 의한 영향을 받을 가능성이 클 것으로 생각된다. 지반침하를 관측하는 일은 공공 방재를 위해서도 필요한 일이다. 본 연구에서는 새롭게 개발된 지표 변위 관측 기법인 영구산란체법(PSInSAR technique)을 이용하여 인천항 연안에서 10여 년 전 발생했던 지표변위를 관측하였다. 해당 지역은 이미 20년 전에 간척이 완료된 지역임에도 불구하고 6년 동안 상당한 변위가 관찰되었다. 지반침하 속도가 최고에 달하는 곳은 3mm/년에 이르기도 했다. 연구에는 JERS-1의 자료가 사용되었다.