• 한국압력기기공학회 논문집
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• 제7권3호
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• pp.23-29
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• 2011

The renewed global interest in nuclear power has arisen from the need to reduce greenhouse gas emissions and to provide sufficient electricity for a growing global population before the accident at Fukushima Dai-ichi nuclear power plant in Japan. In spite of the safety issues of nuclear power plants raised by the ongoing Japanese nuclear crisis, many countries with nuclear power plants (NPPs) are still implementing license extensions of 10~20 years, and even consideration is being given to the concept of life-beyond-60, a further period of license extension from 60 to 80 years. To solving the materials aging problem is integral to its success. To evaluate the plant aging phenomena, a lot of background information such as materials and environment of the parts of the reactor and plant systems is needed by the experts. Information on degradation mechanisms is also used. In this paper, a materials degradation evaluation program called OnMDE-SYS (On-line Materials Degradation Evaluation System) is introduced. The developed program provides a variety of information on the materials and stressors as well as operational experience to the experts. It is also anticipated that the experts can perform materials degradation assessment on the web directly by referring to domestic and international information about the degradation of a nuclear power plants through OnMDE-SYS.

• Journal of Community Nutrition
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• 제2권1호
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• pp.36-49
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• 2000

Evaluation of nutritional status is an essential element in providing appropriate intervention strategies to achieve the highest level of health, Nutritional assessment of the older population is complicated by many factors which do not significantly affect the nutritional status in young adults, therefore, it should be considered in two ways; community-dwelling elders group and hospitalized or institutionalized elderly group. To sort out the individuals with nutritional problems in a community efficiently, nutrition screening tools must be simple, relatively inexpensive, and applicable to a large number of subjects. Combination of tools and indicators such as 24-hour food recall, body weight and height, and questionnaires on eating practices, and the presence of chronic diseases is practically applicable as basic tools of nutritional screening of older age group. However, the lack of validated screening techniques remains a barrier in improving nutrition. Validation is only limited to energy, BMI, protein intake of the older populations living in western countries. Further refinement of nutritional assessment tools is demanded to figure out whether those are practically applicable to community-living older adults in Asian Society. A careful and systematic evaluation of nutritional assessment tools should be carried out prior to implementation of stepwise nutrition service to the heterogeneous older population. For an in-depth nutritional assessment at the individual level, we need to extend research efforts to clarify the requirements of nutrients due to aging and diseases. More cost-effective method that will allow rapid analysis of survey results are needed so that information can be readily available to policymakers.

• 자동차안전학회지
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• 제13권3호
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• pp.102-110
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• 2021

As an alternative to solving safety, environments, and aging problems, ADS (Automated driving system) in the global automotive market is actively being developed as a new growth industry. In time for the appearance of ADS, relevant regulations and assessment programs must also be developed. For example, safety standards for the Level 3 automated driving system were promulgated in December 2019 by the Ministry of Land, Infrastructure and Transport of Korean government. However, assessment programs such as KNCAP for autonomous functions of ADS have not yet been introduced in Korea as well as globally. The autonomous driving functions of ADS at Level 3 or higher must be capable to recognize, judge and respond to objects and events in a wide variety of complex situations. In this paper, we examined and studied the complex situations, considerations and assessment items that ADS must respond to in the interest of safety for passengers, pedestrians and other road users. We hope this paper will be helpful to develop an execution program in the future.

• 한국노년학
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• 제29권4호
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• pp.1327-1340
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• 2009

본 연구의 목적은 일 도시 노인의 성공적인 노화의 수준을 알아보고, 성공적인 노화와 관련된 요인을 규명하는 것이며, 또한 의사결정나무분석 방법을 이용하여 성공적인 노화의 점수에 따른 취약 그룹의 특성을 알아보고 우리나라 노인의 성공적인 노화 증진 프로그램을 개발하는데 기초자료로 활용하기 위함이다. 대구의 일 동사무소에 등록된 노인 중에서 연구 참여에 동의하고 설문지 면접을 마친 총 187명을 대상으로 하였다. 연구 참여에 동의한 노인은 면담자가 직접 노인 가구를 방문하여 구조화된 설문지를 이용하여 성공적인 노화, 우울, 신체적 기능상태, 만성 질환 수, 그리고 친구와의 접촉 빈도수에 대한 정보를 수집하였다. 일 도시의 노인에서 남성, 고학력, 배우자와 사별하지 않은, 그리고 가족과 동거하는 노인이 그렇지 않은 노인에 비해 상대적으로 성공적인 노화의 점수가 높았다. 반면에 우울정도가 심하거나 만성질환이 많을수록 성공적인 노화의 점수가 낮았다. 또한 신체기능과 자가 건강 평가수준이 높거나, 규칙적인 운동을 하거나 친구와의 교제가 많을수록 성공적인 노화의 점수가 높았다. 우울은 노인의 성공적인 노화의 점수에 따른 취약그룹을 분류하는데 일차적으로 중요한 결정 요인이었으며, 성공적인 노화의 점수가 가장 낮은 노인 그룹은 우울정도가 심하고 신체적 기능 상태가 좋지 않았으며, 반대로 성공적인 노화의 점수가 가장 높은 그룹은 우울정도가 약하고 신체적 기능상태가 좋은 노인이었다. 우울과 만성질환은 노인이 성공적인 노화를 경험하는데 부정적인 영향을 미칠 뿐 아니라 성공적인 노화의 점수가 낮은 그룹의 공통적인 특성이었으므로 노인의 우울과 만성질환을 위한 중재 프로그램의 제공이 중요하다는 것을 본 연구는 재확인하였다.

• 대한두경부종양학회지
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• 제39권2호
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• pp.1-6
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• 2023

The aging population, particularly those aged 65 and above, is on the rise, with projections indicating a substantial increase in the elderly demographic. This demographic shift brings challenges in managing age-related diseases, including head and neck cancers (HNCs). Frailty, often characterized by physiological decline and vulnerability to stressors, is a crucial factor affecting treatment outcomes of elderly cancer patients. Accordingly, the significance of assessing frailty in elderly HNC patients before their treatment should be emphasized, but current frailty assessment tools may not fully capture the unique challenges faced by HNC patients. Specific indicators, including respiratory and swallowing functions, are proposed for a more tailored assessment. This comprehensive review explores the impact of frailty on various treatment modalities, including surgery, radiation, and chemotherapy, highlighting the need for personalized interventions. Furthermore, it suggests avenues for future research to enhance frailty assessment tools and investigate interventions aimed at improving treatment outcomes in elderly HNC patients.

• 대한정형도수물리치료학회지
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• 제13권2호
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• pp.79-84
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• 2007

Purpose: The data was performed to evaluate the effect of conservative treatment in 30 patients aging from 21 to 71 with lumbar back pain. Methods: The effect of conservative treatment was analyzed with use of pain behavior scale, pain self assessment scale by Million Index in according to age, occupation, duration of symptom, symptom. Results: The occupation were desking job 43.4%, standing job 33.3%, house wife 23.3%. Duration of symptoms in over 2-5 months was 40.0%. The pain in below 1 months, classified by duration of symptoms, was reduced from 2.1 to 3.0 in pain behavior scale, 6.0 to 2.2 in pain self assessment scale(p<0.05). The pain in only lumbar back pain, classified by symptoms, was reduced from 2.0 to 3.0 in pain behavior scale, 6.6 to 2.4 in pain self assessment scale(p<0.05). Conclusion: The pain in over 9 months. classified by duration of physical therapy, was increase 2.0 in pain behavior scale, 4.0 in pain self assessment scale (p<0.05).

• Structural Monitoring and Maintenance
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• 제3권1호
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• pp.51-69
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• 2016

Monitoring the performance and estimating the remaining useful life of aging civil infrastructure in the United States has been identified as a major objective in the civil engineering community. Structural health monitoring has emerged as a central tool to fulfill this objective. This paper presents a review of the major structural monitoring programs that have been recently implemented in the United States, focusing on the integrity and performance assessment of large-scale structural systems. Applications where response data from a monitoring program have been used to detect and correct structural deficiencies are highlighted. These applications include (but are not limited to): i) Post-earthquake damage assessment of buildings and bridges; ii) Monitoring of cables vibration in cable-stayed bridges; iii) Evaluation of the effectiveness of technologies for retrofit and seismic protection, such as base isolation systems; and iv) Structural damage assessment of bridges after impact loads resulting from ship collisions. These and many other applications show that a structural health monitoring program is a powerful tool for structural damage and condition assessment, that can be used as part of a comprehensive decision-making process about possible actions that can be undertaken in a large-scale civil infrastructure system after potentially damaging events.

• 대한화장품학회지
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• 제42권3호
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• pp.303-309
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• 2016

연령이 증가함에 따라 피부 내부에서는 콜라겐의 합성 능력이 떨어지고 탄력섬유의 손상 및 matrix metalloproteinase (MMPs) 발현이 증가한다. 본 연구의 목적은 눈가에 주름이 형성되기 전에 연령이 증가할수록 피부 내부에서 피부 노화의 징후가 관찰된다는 것을 확인하고, 피부 내부에서 먼저 발생하는 노화의 징후가 칠엽담 지페노사이드 분획물 함유 크림(칠엽담 지페노사이드 크림)의 효능으로 인해 개선되는 것을 확인하는데 있다. 이에 본 연구에서는 육안으로 눈가에 주름이 관찰되지 않는 21 ~ 34세의 한국 여성 52명을 대상으로 임상 시험을 수행하였다. 이들에게서 연령이 증가함에 따라 피부 외부의 노화 징후가 관찰되지는 않지만 피부 내부에서 노화의 징후가 시작되는 시점을 진피치밀도 측정을 통해 확인하였다. 그리고 육안으로 주름이 관찰되지는 않았지만, 진피치밀도가 감소하는 연령대에서 칠엽담 지페노사이드 크림을 4주 및 8주 사용한 후에 진피치밀도 값이 유의하게 증가함을 확인하였다. 따라서 칠엽담 지페노사이드 크림이 피부 내부에서 먼저 진행되는 노화를 효과적으로 개선하는데 도움을 주며, 이 결과를 토대로 칠엽담 지페노사이드 분획물이 향후 주름 개선기능성 화장품 개발에 활용하기 적합하다고 판단된다.

• 한국식품위생안전성학회지
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• 제33권2호
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• pp.140-145
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• 2018

본 연구는 예부터 약용으로 사용되었거나, 현재 식품공전에 식품원료로 사용이 가능한 것으로 등록된 국내 산림지역에 자생하는 식물을 식품산업에 활용하고자 선행연구에서 우수한 항산화 활성을 보인 갈참나무 잎을 본 연구에서 사용하였다. 70% 에탄올을 이용하여 추출한 갈참나무 잎을 이용하여, hydrogen peroxide로 산화적 스트레스를 유도한 피부 섬유아세포에서의 세포 보호효과, 세포내 항산화 효과 및 항노화 효과를 측정하였다. 세포 독성을 평가한 결과 25, 50 및 $100{\mu}g/mL$의 갈참나무 잎 추출물을 처리하였을 때 모두 독성을 나타내지 않았으며, hydrogen peroxide로 산화적 스트레스를 유도한 상태에서는 세포를 보호하여 농도 유의적으로 세포생존율이 증가하였다. 특히, $100{\mu}g/mL$의 농도에서는 양성대조군으로 사용한 $50{\mu}M$ ascorbic acid 수준까지 세포 생존율이 증가하였다. 세포내 항산화 효과를 확인 하기위해 사용한 $H_2-DCFDA$ assay에서는 형광현미경과 형광흡광도 측정에서 모두 농도 유의적으로 세포내 ROS 저감 활성을 확인하였고 갈참나무 잎 추출물을 $100{\mu}g/mL$ 농도로 처리했을 때는 $50{\mu}M$ ascorbic acid와 비슷한 세포내 항산화 효과를 나타내었다. 또한 SA-${\beta}$-galactosidase assay를 이용한 갈참나무 잎 추출물의 피부 섬유아세포에 대한 항노화활성은 ROS 생성 억제 효과와 유사한 경향으로 갈참나무 잎 추출물의 농도 유의적으로 세포 노화 억제효과를 확인하였다. 이상의 결과를 종합하여 볼 때 갈참나무 잎 추출물이 hydrogen peroxide로 인한 산화적 스트레스 상태에서 세포 보호효과, 항산화 효과 및 항노화 효과가 관찰되어 기능성 식품원료로서의 활용도가 매우 넓을 것으로 판단된다.

• Nuclear Engineering and Technology
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• 제44권3호
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• pp.297-310
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• 2012

Aging-related degradation of nuclear power plant components is an important aspect to consider in securing the long term safety of the plant, especially the seismic safety, since the degradation of the components affects not only their seismic capacity but their response. This can cause a change in the seismic margin of a component and the overall seismic safety of a system. To better understand the status and characteristics of degradation of components in Nuclear Power Plants (NPPs), the degradation occurrences of components in the U.S. NPPs were identified by reviewing recent publicly available information sources and the characteristics of these occurrences were evaluated and compared to observations from the past. Ten categories of components that are of high risk significance in Korean NPPs were identified, comprising anchorage, concrete, containment, exchanger, filter, piping systems, reactor pressure vessels, structural steel, tanks, and vessels. Software tools were developed to expedite the review process. Results from this review effort were compared to previous data in the literature to characterize the overall degradation trends.