• Journal of the Society of Cosmetic Scientists of Korea
• /
• v.44 no.3
• /
• pp.239-247
• /
• 2018

Chronic inflammation is known to have effects on various diseases such as gout, cancer, dementia, atopic disease, and obesity. In addition, since some signal cascades involved in the development of inflammation are known to affect the damage and aging of the skin tissue, studies are being conducted actively to control the inflammation mechanism. In order to mitigate or prevent inflammatory response, a number of researches have been made to develop anti-inflammatory materials from some plants. In particular, Stevia rebaudiana produces steviol glycosides (SG), a natural sweetener with a distinctive flavor. Studies on some of SG have been shown to have anti-inflammatory activity. Researchers of this study expected that more SG also possess anti-inflammatory activity, besides stevioside, rebaudioside A, and steviol. In order to confirm this possibility, the researchers screened inhibition activity of various steviol glucosides for NO production in RAW 264.7 cell lines. As a result, steviol ${\beta}-glucopyranosyl$ ester (SGE) showed the highest inhibitory activity among steviol derivatives treated at the same molar concentration. In addition, we found that mRNA expression level of $interleukin-1{\alpha}$ ($IL-1{\alpha}$), $interleukin-1{\beta}$ ($IL-1{\beta}$), cyclooxygenase-2 (COX-2), nuclear factor kappa-light chain-enhancer of activated B cells ($NF-{\kappa}B$) and inducible nitric oxide synthase (iNOS) was also decreased in a dose-dependent manner. These results show that SGE inhibits anti-inflammatory activity and NO production in mouse macrophage RAW 264.7 cells. It was confirmed that SGE has potential to be applied as an anti-inflammatory material.

• Journal of the Korea Convergence Society
• /
• v.11 no.12
• /
• pp.329-341
• /
• 2020

As COVID-19 pandemic sweeps across the world, more than 45 million confirmed cases and over 1,000,000 deaths have occurred till now, and this situation is expected to continue for some time. In particular, more than half of the infections in European countries such as Italy and Spain occurred in nursing homes, and it is reported that over 4,000 people died in nursing homes for older adults in the United States. Therefore, the issues that need to be addressed after the COVID-19 crisis include finding a fundamental solution to group care and shifting to family-centered care. More specifically, it is expected that there will be ever more lively discussion on establishing and expanding hyper-technology based community care, that is, family-centered care integrated with ICT and other Industry 4.0 technologies. This poses a challenge of how to combine social security and social welfare with Industry 4.0 in concrete ways that go beyond the abstract suggestions made in the past. A case in point is the proposal involving smart welfare cities. Given this background, the present paper examined the concept, scope, and content of non-face-to-face care in the context of previous literature on the function and scope of the social security platform, and the concept and expandability of the smart welfare city. Implementing a smart city to realize the kind of social security and welfare that our society seeks to provide has significant bearing on the implementation of community care or aging in place. One limitation of this paper, however, is that it does not address concrete measures for implementing non-face-to-face care from the policy and legal/institutional perspectives, and further studies are needed to explore such measures in the future. It is expected that the findings of this paper will provide the future course and vision not only for the smart welfare city but also for the social security and welfare system in administrative, practical, and legislative aspects, and ultimately contribute to improving the quality of human life.

• Journal of Korean society of Dental Hygiene
• /
• v.11 no.2
• /
• pp.233-242
• /
• 2011

Objectives : The purpose of this study is to provide the basic data for searching for the method to induce more positive knowledges and attitudes about the old from the university students majoring in dental hygienics, health and social welfare university students majoring in the old, who will face the change of aging society directly. Methods : The study selected 1 school in Busan and Daegu respectively with convenience sampling from September 2010 to October 2010, performed questionnaire(self administered questionnaire) to 401 students majoring in dental hygienics, health and social welfare and achieved following conclusions. Results : 1. When the students without the education experience about the old have negative experiences, the degree of interest in the old was high and when they have positive experiences, the attitude score about the old was high(p<0.001). 2. For education experience about the old, the students majoring in dental hygienics have the lowest experiences(p<0.001). 3. For knowledge, attitude and behavior about the old depending on major, the students majoring in social welfare have the highest interest and for the knowledge about the old in physical area, the students majoring in health have the highest knowledge(p<0.01).4. The area related with the knowledge about the old showed significant correlation in all of physical, psychological and social area(p<0.001). 5. The factors giving effects to the attitude about the old were gender(p=.006), experience(p=.003) and education experience related with the old(p=.022) and the factors giving effects to the behavior about the old were experience(p=.036) and attitude about the old(p=.000). Conclusions : It is necessary to develop actual education program that can provide preliminary dental hygienists with positive attitude about the old and reflect a lot of matters related with psychological area and social area about the old. In addition, it is necessary to establish the opportunity to understand the old through voluntary service activity related with the old in connection with local community. It is necessary to recognize the old positively by showing the positive figure.

• Journal of Life Science
• /
• v.23 no.6
• /
• pp.751-756
• /
• 2013

This research old age chestnut tree that loss function chestnut leaf renewal efficiency enlargement and development of cosmeceutical product by purpose. Chestnut leaf (CL) exhibits numerous pharmacological effect including anti-allergy and anti-microbial properties. However, the anti-wrinkle effect of CL is not completely understood. In this study, to find a possible explanation for the anti-wrinkle effects of CL, we evaluated the effects of CL on radical scavenging activity, elastase inhibition activity and collagenase inhibition activity. CL was extracted with various solvents including water (CLW), 70% ethanol (CLE) and 70% acetone (CLA). The results showed that CLW, CLE, and CLA have the radical scavenging activity. In addition, we showed that CLW, CLE, and CLA have the elastase inhibition activity and collagenase inhibition activity. Consequently, the CL has a potent anti-wrinkle effect and it could be a useful cosmeceutical product for anti-aging purposes.

• Journal of the Korea Institute of Building Construction
• /
• v.18 no.5
• /
• pp.419-427
• /
• 2018

The purpose of this study is to recycle steel slag generated from the iron producing process and to use steel slag as a construction material which is currently landfilled Steel slag is subjected to aging treatment due to the problem of expansion and collapse when it reacts with water. The Slag Atomizing Technology (SAT) method developed to solve these problems of expanding collapse of steel slag. In this study, experimental study on the emergency repair mortar using the reducing slag, electric arc furnace slag and silicon manganese slag manufactured by the SAT method is Reduced slag was shown an accelerated hydration when it was replaced with rapidly-setting cement, and the rate of substitution was equivalent to 15%. It is shown that the electric furnace oxide slag is equivalent to 100% of the natural aggregate, and it can be replaced by 15-30% when the silicon manganic slag is substituted for the electric furnace oxide slag. With the above formulation, it was possible to design the rapidly repair mortar for road use. These recycling slags can contribute on achieving sustainability of construction industry by reducing the use of cement and natural aggregates and by reducing the generation of carbon dioxide and recycling waste slag.