• Title/Summary/Keyword: Agent Program

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The Study on a Various Parameter for the CT Test and the Patients-Anxiety of Factor Related (CT검사 시 다양한 매개변수와 환자의 불안 요인에 관한 연구)

  • Baek, Cheol-Oh;Han, Man-Seok
    • Journal of radiological science and technology
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    • v.34 no.2
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    • pp.149-156
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    • 2011
  • This study is to identify perceptions and response degrees of anxiety for each factor, targeting patients for CT test and analyze the relations between factors. It is to provide scientific fundamental data to reduce anxiety by improving awareness of patients about CT test by analyzing relations between variables. The subjects of this study were surveyed in self-writing type, targeting 263 patients for CT test in the department of radiology at three University hospitals from July to September, 2010. This survey was executed once by a structured self-administered survey type. The targeting patients for CT test of anxiety will investigate for affect. Anxiety by each CT test variables depending on CT test-related features showed independent variable is Expense Responsibility, Economic burden, Sufficient explain, Explain agent, Endoscope, Biopsy, Pre treatment, Previous experience, CT side effect experience, Side effect of contrast medium and dependent variable is physical, Hospital staff, Hospital environment, Socioeconomic These used statistics program SPSS (ver. 13.0). Summarizing the above results of this study, awareness of anxiety and response to it in each variable under CT test appeared significant differences in economic burdens, state anxiety, pre-treatment anxiety, exposure anxiety to radiation, and anxiety of side effect. Therefore, pre-treatment before test and pre-training programs on chemical poison of contrast medium and side effect seem to be able to release patients' anxiety level for CT test. Ways to meditate these anxiety variables and reduce degree of anxiety are needed to be researched more and updated. In addition, impact of patients' economic burdens on CT test anxiety is required to be recognized and solved in society level.

A Study on the Perception Level of Nursing Activities of Nurses in General Hospitals (일부 대학병원 간호사의 업무인지정도에 관한 조사연구)

  • Kim, Chun-Gil
    • The Korean Nurse
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    • v.30 no.1
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    • pp.51-62
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    • 1991
  • The Study was carried out for the purpose of investigating the degree of perception in nursing activities. This study reports perceptions of nurses on the choices they make among competing activities, contrasts this perception with their opinion of what tasks they would like to spend time on. A sample of 231 clinical nurses was selected to participate in this study at two genernal hospitals in Seoul. The data was collected from July 10th to 25th, 1990. Subjects were instructed to rate one of five points likert type scale on the 43 items of nursing activities. Analysis of data was done by means of the SPSS-X Program using frequency, t-test and ANOVA. The results of this study were as follows; 1. The characteristics of the subjects were as follows: The age group of 25-29 yeares was 45.9%. For religion, Christians had the highest score, 68.4 % and singles in subjects were 81.4%. For academic background, 64.5% were graduated from nursing junior colleges. In the subjects, staff nurses were 86.6%. 22.5% of them had worked for less than 1 year and 20.8% had 37 months to 5 years experience at the time of the survey. 62.8% were satisfied with the job. 2. The perception level of nursing activities: 1) The mean score for perception of professional nursing functions was 4.157 point, with a maximum score set. at 5 points. The mean score for perception of priorities was 3.781. Perception of spending time was 3.932. 2) In perception of professional nursing functions, more important items were Aseptic technique (4.866), Shift and exchange of information concerning patients(4.654), Observing patients (4.799). Less important items were Transporting patients(3.411), Changing linens(3.442), Giving a bed shampoo (3.506). In priorities, more important ones. were Aseptic technique(4, 706), Shift and exchange of information concerning patients (4.524.), Observing patients(4.390), Taking vital signs (4.355). And less important ones were Changing linens (3.100), Giving bed baths(3.113), Giving back rubs(3.121). In spending time, more important ones were Aseptic technique(1.706), Observing patients (4.532), Shift and exchange of information concerning patients(4.532). And less important ones were Changing lines(3.368), Transporting patients(3.394), Giving bed baths(3.450). 3) In the role perception level, the mean distribution of perception was 3.511- 4.335; the role was perceived to be in order of frequency as a facilitator, coordinator, change agent and advocator role. The most important scale of factors by nursing activities was indirect nursing activities.

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Study of SNCR Application to Industrial Boiler for NOx Control (산업용 보일러의 질소산화물 제어를 위한 SNCR 적용 연구)

  • Shin, Mi-Soo;Kim, Hey-Suk;Jang, Dong-Soon
    • Journal of Korean Society of Environmental Engineers
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    • v.27 no.3
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    • pp.286-292
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    • 2005
  • This study is to investigate the industrial boiler which can be significantly affected by the restriction of NOx. Note that the application of SNCR method to industrial boiler is usually blown as not feasible due to the insufficient residence time for proper mixing. The purpose of this study is to investigate the applicability of the SNCR system application to the industrial boiler, which produces 40 tons of steam per hour using heavy oil. For the industrial boiler with 3-D rectangular coordinate, the general coding are made fur various turbulence modeling such as turbulent flow, turbulent fuel combustion, thermal NO formation and destruction together with the NO reaction with reducing agents. Further, the incorporation of drop trajectory model is successfully made in 3-D rectangular coordinate with Lagrangian frame and the main swirl burner effect on the characteristics of flame is considered. As expected a short flame was created and thereby NOx is removed more efficiently by increasing the proper region of temperature for NO reduction reaction. The validation of program was made successfully by the comparison of experimental data. Based on the reliable calculation results, the SNCR method in a industrial boiler shows the possibility as one of viable NO reduction method by the use of well designed mixing air of reducing agent.

A New Class of Platinum (II) Complexes [Pt (trans-1-daeh) (DPPP)] $2NO_3$ and [Pt (trans-1-daeh)(DPPE)] $2NO_3$ Exhibiting Antitumor Activity and Nephrotoxieity (새로운 Platinum (II) Complex ([Pt (II)(trans-1-dach)(DPPP)] $(NO_3)_2$와 [Pt (II)(trans-1-dach)(DPPE)] $(NO_3)_2$의 항암효과 및 신독성에 관한연구)

  • Jung, Jee-Chang;Yoon, Chin-Hee;Chang, Sung-Goo;Lee, Kyung-Tae;Rho, Young-Soo
    • The Korean Journal of Pharmacology
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    • v.29 no.2
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    • pp.283-295
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    • 1993
  • Pt-complexes is currently one of the most compounds used in the treatment of solid tumors. However, its used is limited by severe side effects such as renal toxicity. Our platinum-based drug discovery program is aimed at developing drugs capable of diminishing toxicity and improving antitumor activity. We synthesized new Pt (II) complex analogues containing 1, 2-diaminocyclohexane (dach) as carrier ligand and 1, 3-bis (diphenylphosphino) propane (DPPP)/1,2-bis (diphenylphosphino) ethane (DPPE) as a leaving group. Furthermore, nitrate was added to improve the solubility. A new series of (KHPC-001) [Pt (trans-1-dach)(DPPP)] $2NO_3$ and (KHPC-002) [Pt (trans-1-dach)(DPPE)] $2NO_3$ were synthesized and characterized by their elemental analysis and by various spectroscopic techniques [infrared (IR), $^{13}carbon$ nuclear magnetic resonance (NMR)]. KHPC-001 and KHPC-002 demonstrated acceptable antitumor activity aganist P-388, L-1210 lymphocytic leukemia cells and significant activity as compared with that of cisplatin. The toxicity of KHPC-001 and KHPC-002 was found quite less than that of cisplatin using MTT, $[^3H]$ thymidine uptake and glucose consumption tests in rabbit proximal tubule cells and human kidney cortical cells.

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Antioxidant properties of brownish natural dyeing agents from medicinal plant (갈색계 천연색소 추출물의 항산화 특성)

  • Kim, Yeon-Soon;Kwon, O-Jun;Suh, Hwa-Jin;Park, Shin
    • Food Science and Preservation
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    • v.23 no.3
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    • pp.387-392
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    • 2016
  • The antioxidant activities of brownish natural dyeing agents, extracted from seven kinds of plants, were tested. Total polyphenol content, DPPH and ABTS radical scavenging activities, and singlet oxygen quenching effect were determined for hot water extracts and floral waters of plants. DPPH and ABTS radical scavenging activites increased with increasing amounts of the extracts from Uncaria gambir R. and Terminalia chebula R. displayed remarkable scavenging effects at concentrations below 0.1 mg/mL, in comparison with the positive control, ascorbic acid. However, antioxidant effects of the floral water, obtained from steam distillation of tested plants, were inefficient at concentration below 0.2 mg/mL. In particular, the natural dyeing agent effectively suppressed singlet oxygen induced by photosensitizer in in vitro assay systems. The concentrations ($IC_{50}$) required to exert 50% of singlet oxygen were 120 and $190{\mu}g/mL$ for hot water extracts from Uncaria gambir R. and Phellinus linteus, respectively. Among all the tested samples, the Uncaria gambir R. and Phellinus linteus extracts contained higher amount of total phenolic contents. The results suggest that naturally occurring dyeing agents are beneficial as natural antioxidants, encouraging further extensive studies.

Estimation of Flowability and Strength in Controlled Low Strength Material Using Multiple Regression Analysis (다중회귀분석을 이용한 CLSM의 유동성 및 강도 특성 예측)

  • Han, WooJin;Lee, Jong-Sub;Byun, Yong-Hoon
    • Journal of the Korean GEO-environmental Society
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    • v.18 no.12
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    • pp.65-75
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    • 2017
  • Flowability and strength with curing time of controlled low-strength material (CLSM) are required differently according to the construction purpose. In this paper, the flowability and strength were estimated from the mixing ratio of CLSM using multiple regression analysis to design the CLSM. The flow values and strength at 12 hrs and 7days were measured in accordance with the mixing ratio of CLSM which consists of 7 different materials, such as CSA expansive agent, ordinary Portland cement, fly ash, sand, silt, water, and accelerator. The multiple regression was performed with the proportions of each material of CLSM as independent variables and the measured properties as dependent variables using SPSS Statistics 23 which is a statistical analysis program. The regression coefficients were estimated from the first to third order equation models for the materials. From the results, the third order model for the flow values and the first order models for 12hrs and 7days strength are the most appropriate models. This study suggests that the mixing ratio required for constructions may be effectively estimated from the regression models about the characteristics of CLSM, before performing experimental tests.

Knowledge and Attitudes of Oncology Nurses Toward Cancer Pain Managements (암 병동 간호사의 통증관리에 대한 지식과 태도)

  • Gong, Soung-Wha;Bang, Jji-Yha;Seo, Min-Sook;Hyun, Sin-Sook;Kim, Hee-Jung;Lee, Mi-Ae;Lee, Mi-Ae;You, Hyen-Hee;Her, Jae-Kyoung;Kim, Eun-Ae;Park, Kyung-Sook
    • Korean Journal of Adult Nursing
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    • v.16 no.1
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    • pp.5-16
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    • 2004
  • Purpose: The purpose of this study is to evaluate the knowledge and attitudes of oncology ward nurses toward cancer pain management and to find ways to improve the educational program for nurses. Method: A total of 209 nurses working at the oncology ward of three hospitals in Seoul and a Gyenggi Province. The survey instrument used was the 32-item scale for evaluating nurses knowledge and attitudes originally developed by McCaffery and Ferrell'(1990), that was by Kim'(1997). Result: In terms of the nurses knowledge of pain management, the result showed that the nurses scored an average of 67.8 out of 100 for phamacokinetics of opioids, 84.8 for classification of analgesics, 60.1 for pain assessment, and 70.7 for drug administration. 18.2% of the nurses hesitate to inject the narcotic agent because of concerns regarding the drug's potential side effects. there was significant difference in the knowledge of pain management according to the general characteristics of pain in terms of the nurses age(p=.001), position (p=.016), years of experiences(p=.002), experience of cancer pain education(p=.001). Conclusion: The also showed that nurses working at cancer ward lack knowledge. It is important to provide intensive education to nurses about cancer pain management.

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Challenges and Possible Ways to Facilitate Busan New Port Logistics (국내외 물류환경 변화에 따른 부산 신항의 항만물류상 문제점과 활성화 방안)

  • Kim, Jeong-Su;Sin, Gye-Seon;Choe, Hak-Su
    • Journal of Korea Port Economic Association
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    • v.24 no.3
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    • pp.79-99
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    • 2008
  • All the major ports around the world as well as those in Korea have been exploring their own strategies to survive rapidly changing marine transport environment worldwide. In particular, Busan New Port under development still fails to meet expected logistical traffic, although it operates 6 berths. That is why it is necessary to point out current challenges in logistical strategy of Busan New Port for fully dealing with logistical traffic. Therefore, this study can propose the following ways to facilitate logistical traffic of Busan New Port. First, it is necessary to apply equal tariff to incentives given to shipping agent under the associations between existing harbors and Busan New Port. Second, it is required to increase governmental subsidy for truck freight transport. Third, it is demanded to seek possible ways to transport export and import freight and thereby create independent logistical traffic. Fourth, it is necessary to contact shipping agents residing in new ports and establish a logistical program for shipping freights via Europe, Middle East and Russia as well as those by way of North America, Japan, Korea and China, ultimately making sustainable marketing strategy to create a series of continuous transshipment freight, not temporary one. Finally, it is advisable to operate networked logistical programs with small- or medium-sized overseas shipping agents in business association with large-scale overseas shipping agents.

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Exposure Assessment of Hazardous gases in Confined Spaces (밀폐공간 종류별 유해가스 발생 농도 평가)

  • Park, Hyunhee;Yoo, Kye-mook;Ham, Seung-hon;Chung, Kwang-Jae;Shin, Min-a;Lee, Koo-yong;Jang, Kyung-jo;Yoon, Chung-sik
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.19 no.4
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    • pp.381-389
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    • 2009
  • Confined spaces are inherently dangerous workplace and many fatal and nonfatal accidents have been reported. Even though these accidents occur in various kinds of confined spaces, there has rarely been reported on the health hazard agent, i.e., the types of gases and their concentration ranges. Therefore in this study, we evaluated several toxic and asphyxiating gas concentrations in various confined spaces. We surveyed 57 manholes, 3 sewage treatment plants, 2 yellow radish manufacturing companies and 7 barges to measure the concentrations of oxygen($O_2$), hydrogen sulfide($H_2S$), carbon monoxide(CO), ammonia($NH_3$). Lower Explosion Limits(LEL) and Volatile Organic Compounds (VOCs). Those four types of confined spaces occupies 56% of accidents during last 9 years in Korea. In 57 manholes, the concentration varied according to the types of manholes; rainfall and sewage, and by location; residential and industrial areas. Sewage manhole in industrial area was evaluated as the most hazardous than other types of manhole like rainfall manholes, residential sewage manholes. The highest $H_2S$ concentration and the lowest $O_2$ concentration at sewage manhole in industrial area were 300 ppm, 8.7% respectively. In 3 sewage treatment plants, $H_2S$ and $NH_3$ concentrations were reached up to the 500 ppm and 200 ppm respectively. Two yellow radish manufacturing companies showed the concentrations of 316 ppm, 505.2 ppm, 90 ppm and 15.7% for $H_2S$, CO, VOCs and $O_2$, respectively. Seven barges showed 15.9%~20.9% oxygen concentration. Gas species and concentration ranges varied by the types and location of confined spaces; CO, $H_2S$, $O_2$ could be hazardous in manhole, especially manhole connected to sewage plants. CO, $H_2S$, LEL, $O_2$, $NH_3$ should be controlled in sludge silo and sluge pumping confined spaces in sewage treatment plant. The activity of lifting out radish from the storage tank was evaluated more hazardous rather than the other activities in yellow radish manufacturing industry. The employers must conduct the survey to identify all possible confined spaces in their local workplace prior to performing the tasks. At the national level to reduce the accidents in the confined spaces, we suggest that systemic approach and active education program including possible hazards, standard operation procedures, ventilation plan, and personal protective equipment in confined spaces should be implemented.

Repeated Dose and Reproductive/Developmental Toxicities of Acetanilide in Rats (랫드를 이용한 Acetanilide의 반복투여 및 생식/발생독성 병행시험)

  • Chung, Moon-Koo;Baek, Sung-Soo;Lee, Sang-Hee;Kim, Hyun-Mi;Choi, Kyung-Hee;Han, Sang-Seop
    • Toxicological Research
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    • v.23 no.4
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    • pp.391-403
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    • 2007
  • The study was conducted to assess the repeated dose and reproduction and developmental toxicities of acetanilide, an intermediate for drug production, as a part of OECD Screening Information Data Set (SIDS) program. The test agent was administered by gavage at dose levels of 0, 22, 67, 200 and 600 mg/kg to Sprague-Dawley rats (12/group/sex) during pre-mating and mating period for males(up to 30 days) and females and pregnancy and early lactation period for females (up to 39-50 days). At 22 mg/kg, decreases in HGB, HCT (males) and MCHC (females), hyperplasia of spleen red pulp, hyperplasia of femur bone marrow (both sexes) were observed. At 67 mg/kg, salivation (males), reduced food consumption (both sexes), decreases in RBC, HGB, HCT and MCHC (males), increases in MCV (males) and spleen weight (males), hyperplasia of spleen red pulp and femur bone marrow (both sexes) were observed. At 200 mg/kg, decreases in locomotor activity and salivation (both sexes), reduced food consumption (both sexes), decreases in RBC, HGB, HCT and increases in MCV, MCH, BUN, T-BIL (males), enlargement of spleen (both sexes), increased weight of spleen (males), hyperplasia of spleen red pulp and femur bone marrow and extramedullary hematopoiesis of liver (both sexes), atrophy of thymus and corpus luteum hyperplasia of ovary (females) were observed. At 600 mg/kg, decreases in locomotor activity, cyanosis (both sexes), reddish tear, and salivation (males), mortality (4 out of 12 females), decreased body weight (females), reduced food consumption (both sexes), decreases in RBC, HGB, HCT and MCHC and increases in WBC, MCV, MCH, reticulocyte, neutrophil, lymphocyte, monocyte, AST, ALT, BUN, T-BIL, ALB, Ca and A/G ratio (males), enlargement of spleen, increased weights of spleen (both sexes), liver (males), kidney and ovary, decreased weights of thymus (females), hyperplasia of spleen red pulp, hyperplasia of femur bone marrow and extramedullary hematopoiesis of liver (both sexes), and atrophy of thymus and corpus luteum hyperplasia of ovary (females) were observed. Regarding the reproduction and development toxicities, there were no treatment-related changes in precoital time, mating index, fertility index and pregnancy index at all doses tested. At 22 and 67 mg/kg, there were no adverse effects on all the parameters observed. At 200 mg/ kg, decreased body weight of pups (day 4 p.p.) were observed. At 600 mg/kg, decreased body weight of pups (day 0 and 4 p.p.) and viability index (day 4 p.p.), increased incidence of newborns dead or with abnormal clinical signs were observed. The results suggest that the NOAELs for general toxicity are < 22 mg/kg, LOAELs are 22 mg/kg and the NOAELs for reproductive toxicity are 67 mg/kg.