• Korean Journal of Biological Psychiatry
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• v.21 no.3
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• pp.81-86
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• 2014

Objectives Total intracranial volume (TIV) is a major nuisance of neuroimaging research for interindividual differences of brain structure and function. Authors intended to prove the reliability of the atlas scaling factor (ASF) method for TIV estimation in FreeSurfer by comparing it with the results of manual tracing as reference method. Methods The TIVs of 26 normal children and 26 children with attention-deficit hyperactivity disorder (ADHD) were obtained by using FreeSurfer reconstruction and manual tracing with T1-weighted images. Manual tracing performed in every 10th slice of MRI dataset from midline of sagittal plane by one researcher who was blinded from clinical data. Another reseacher performed manual tracing independently for randomly selected 20 dataset to verify interrater reliability. Results The interrater reliability was excellent (intraclass coefficient = 0.91, p < 7.1e-07). There were no significant differences of age and gender distribution between normal and ADHD groups. No significant differences were found between TIVs from ASF method and manual tracing. Strong correlation between TIVs from 2 different methods were shown (r = 0.90, p < 2.2e-16). Conclusions The ASF method for TIV estimation by using FreeSurfer showed good agreement with the reference method. We can use the TIV from ASF method for correction in analysis of structural and functional neuroimaging studies with not only elderly subjects but also children, even with ADHD.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.10
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• pp.5257-5261
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• 2012

Background: High incidence of breast cancer and its fatal effect has reached an alarming stage across the globe, including the third world countries. Many factors have been reported to be associated with the development of breast cancer but detailed structural and functional information is missing. CA 15-3 is one of the known potential tumor marker of breast cancer; however little is known about structure and functional site of this protein. Present study aims to investigate the functional role of CA 15-3 in breast cancer, especially in development and metastasis. Material and Methods: Hundred female breast cancer patients confirmed by histopathological reports were included in the study. Their physiological characters were recorded in a performa. Enzyme linked immunosorbent assay (ELISA) technique was used to estimate serum CA 15-3 level. Immunohistochemistry was done for estrogen (ER), progesterone (PR) and Her2/neu receptors expression. Results: The study revealed the details of physiological characteristics of female breast cancer. Mean age was $37.72{\pm}5.99$ and $55.05{\pm}7.28$ years and serum CA 15-3 (MUC1) level was $60.47{\pm}8.59$ and $63.17{\pm}4.58$ U/ml in pre and post-menopause respectively, and both groups of women had sedentary life style. Their receptor status especially of progesterone, estrogen and HER-2/neu were positive in 50% of premenopausal women and 65% of postmenopausal women. Conclusion: There are multiple physiological factors promoting breast cancer. High serum CA 15-3 level and hormonal imbalance of ER, PR and Her2/neu appears to be the main cause of breast cancer. It may be possible that the functional sites of these proteins may be altered which may increase the chances of metastasis in breast cancer.

• The Journal of the Korea Contents Association
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• v.16 no.1
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• pp.403-414
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• 2016

This study aims to examine the influence of job stress on the depression conducted with 360 police officers working at police station branch and police box in Chungbuk area, and they were divided into two sub-groups based on the age of 50 in order to analyze the buffering effect of organizational health in the relationship between job stress and depression. The main results of this study are as follows. First, the level of depression in the group older than 50 and younger than 50 were 3.22 and 2.90 respectively showing that in the group older than 50 were significantly higher. Second, the factors that influence the depression were shown to be similar for each group, but significantly different for their influence of each group. The factors that influence the depression in the group older than 50 were shown in the order of organizational structure, job stress, readership. The factors that influence the depression in the group younger than 50 were shown in the order of job stress, police officers ability, readership. Third, in the relationship between job stress and depression, buffering effects of organizational health were identified to be different in each group. Based on these results, several ways were suggested to prevent or ease the job stress and depression of police officers.

• Journal of Korean Society of Forest Science
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• v.96 no.6
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• pp.705-713
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• 2007

The purpose of this study was to understand the organization and the forestry household income applied the result of 2005 Forestry Census and the Economic survey of Forest household in Korea. As a result of the analysis, there are 97,108 households of a forester in korea 2005. Full time forestry household occupied 7,925 families (8.2%), part time forestry household occupied 88,183 families (91.8%). Therefore, the most household of a forester is part time forestry household in korea. The average people of the household of a forester family is 2.7 people. The age of forest manager are sixties nearly, over sixty years old forest manager occupied 51,505 people (53%). The forest management period of forestry households is more than 6 months in 39,229 families (40.4%), less than 1 month in 7,216 families (7.4%). The average area of forestry households owning forest is 4.6ha. According to the type of business, logging families possesses 19.5 ha. The mean income of forestry households is \27,148,000. One of them, forestry income is \6,529,000, which occupied 24.1%. Furthermore, forestry households less than \5,000,000 forest product sales performance occupied 51,633 families, which is 64%. Forest operating costs is \6,566,000 mean per family. In addition, the number of a forestry household resident villages is 11,829 villages, where is 32.8% of whole villages in korea. There are 2,979 villages where reside forestry household in gyeongsangbuk-do.

• Asian-Australasian Journal of Animal Sciences
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• v.23 no.5
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• pp.640-648
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• 2010

Insulin-responsive glucose transporter 4 (GLUT4) is a member of the glucose transporter family and mainly presents in skeletal muscle and adipose tissue. To clarify the molecular structure of porcine GLUT4, RACE was used to clone its cDNA. Several cDNA clones corresponding to different regions of GLUT4 were obtained by amplifying reverse-transcriptase products of total RNA extracted from Landrace porcine skeletal muscles. Nucleotide sequence analysis of the cDNA clones revealed that porcine GLUT4 cDNA was composed of 2,491 base pairs with a coding region of 509 amino acids. The deduced amino acid sequence was over 90% identical to human, rabbit and cattle GLUT4. The tissue distribution of GLUT4 was also examined by Real-time RT-PCR. The mRNA expression abundance of GLUT4 was heart>liver, skeletal muscle and brain>lung, kidney and intestine. The developmental expression of GLUT4 and insulin receptor (IR) was also examined by Real-time RT-PCR using total RNA extracted from longissimus dorsi (LM), semimembranosus (SM), and semitendinosus (SD) muscle of Landrace at the age of 1, 7, 30, 60 and 90 d. It was shown that there was significant difference in the mRNA expression level of GLUT4 in skeletal muscles of Landrace at different ages (p<0.05). The mRNA expression level of IR also showed significant difference at different ages (p<0.05). The developmental change in the mRNA expression abundance of GLUT4 was similar to that in IR, and both showed a higher level at birth and 30 d than at other ages. However, there was no significant tissue difference in the mRNA expression of GLUT4 or IR (p>0.05). These results showed that the nucleotide sequence of the cDNA clones was highly identical with human, rabbit and cattle GLUT4 and the developmental change of GLUT4 mRNA in skeletal muscles was similar to that of IR, suggesting that porcine GLUT4 might be an insulin-responsive glucose transporter. Moreover, the tissue distribution of GLUT4 mRNA showed that GLUT4 might be an important nutritional transporter in porcine skeletal muscles.

• Journal of Global Scholars of Marketing Science
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• v.15 no.1
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• pp.41-60
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• 2005

The purposes of this study were 1)to examine the conceptual structure of purchasing motives and information seeking of beauty service, 2)to find out the effects of purchasing motives on information seeking, and 3)to investigate the differences of purchasing motives and information seeking according to the demographic variables. The questionnaire was developed based on pretest and previous studies, and completed by 331 female consumers living in Seoul and Busan. Data were analyzed by factor analysis, Cronbach's a, regression analysis, Pearson's correlation, ANOVA, and Duncan test. The results are as follows; First, factor analysis showed that the purchasing motives of beauty services consisted of five factors, such as Fashionableness, Impulse purchase, Special event, Mood & Recreation, and Practical purchasing needs. And the information seeking for beauty services consisted of four factors, such as Mass media, Opinions of neighbors, Experience & Observation, and Sales hook. Second, mass media was effected by fashionableness, impulse purchase, special event, and mood & recreation. Experience & Observation was effected by fashionableness, special event, and mood & recreation. Sales hook was effected by fashionableness, and impulse purchase. Third, the dimensions of purchasing motives and information seeking of beauty service were significantly different according to age, marriage or unmarried, and duties.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.13 no.4
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• pp.35-48
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• 2018

This study aims to assess the training effect of QFD(Quality Functional Deployment) program for 3 years over startups, adopted from the conventional QFD widely used in the large companies to break up to a sluggish sales and growth, for employees working in startup whether the participants in startup and venture company taking this lessons into their real tasks or not. In particular, the focus of this study falls on figuring out whether individual characteristics of the participants play a role in moderating effect over transfer intension factors and its link path structure. The research results drive out two significant findings. First, in terms of relationship between the influence of transfer intension by self-efficacy and the validity of training content with the learner's readiness, the moderating effect of demographic features of the participants is effective partially by the sex and fully by their working position, but not statistically significant by age, education, and the prior startup career. This research deliver the following significant implication that the active participation of CEO level, decision-maker guarantee the higher performance of the training program like QFD program, more stresses falling on practical implementation in real business rather than just ending up with career training. This study gives significant policy implication to quasi-government organization running all public startup training projects.

• Water for future
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• v.15 no.2
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• pp.11-22
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• 1982

This study is to find out the reasonable drainage system of sewerage in connection with the geographical conditions, the form of city, and the problem of sewerage in and around Seoul. (1) In supplying the sewerage sewer, the separating system is desirable in connection with the problem of sewerage disposal in future. However, in the existing urban district, the conjunction system is used because of the large amount invested according to the diversion of the sewer of the separation system and the influence of the traffic communication. The sewer of the separating system should be used in the case of the fundamental reconstruction of structure as the redevelopment of the urban district or the subway and new-development of area. Therefore, the separating system should be used completely until the goal year. (2) Drainage area was divided for the natural flowing, considering that the 38 streams and topography paly a role of the main stream of drainage. There are the branches, Guyui, Dug-island, Jayang, Hannam, Banpo, Amsa whose divisions are impossible. In these branches, the drain planning was suggested a forced control method by using the exiting pond age and the pumping station. (3) The best available method which improbes the water quality in Han river is as follows. The sewerage is catched and carried to the sewerage disposal plant by establishing the intercept sewer in both or one side of stream. At the same time, the groudwater volume which springs in each stream is drained separatively.

• Journal of the Korean Institute of Landscape Architecture
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• v.35 no.4
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• pp.90-104
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• 2007

Landmarks like high-rise building are one of the important elements for the enhancement of city identity and provides the hierarchy of city streets, playing a central and symbolic role in cities. Research on physical attribute of landmarks, such as height, distance, location and shape, which are suitable for a city scale, can help a city create a distinct image and maintain comprehensible structure. To achieve this purpose, it is necessary to understand the spatial and cognitive characteristics of a landmark for the establishment and management of it. The results of this study can be summarized as follows: 1. The level of representativeness of a landmark increases in proportion to the degree of cognitive intensity on it. The relation between representativeness and cognitive intensity can be explained as the log-function as follows: Log(the number of people who respond "It has representativeness")=$-1.2579+1.5908{\times}$(cognitive intensity); 2. There are a few differences based on the attributes of respondents: while gender has no distinct influence, residential period and age show statistically meaningful influence on cognitive intensity of a vertical landmark Cognitive intensity of an individual landmarks especially, differs according to the class of main users. Because of frequent changes in occupation or employment, respondents consider the distance from a residential area more important than the distance from a working area in evaluating cognitive intensity of landmarks; 3. landmark can be classified into two kinds: a district landmark and an urban landmark A district landmark is closely connected with physical attributes of the landmark itself, such as distance, size and height. An urban landmark is mainly related to cognitive attributes such as the image and identity of a city as a whole. As a result, the landmark analysis data in this research provides spatial order and identity in a city. It is difficult to establish and reinforce the image of a city as a single element ike a landmark. However, withy steady follow-up research, this study could be seen as a systematic and logical model to improve urban landscape and image.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.8
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• pp.192-199
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• 2016

This article examines the location strategies of coffee franchises in Gyeonggi province. Due to its large population, broad area, and diverse industrial structure, Gyeonggi province is an ideal dataset for empirical testing of the location strategies. We collect the addresses of five major coffee franchises stores, convert them into geographic coordinates using Google Maps Geocoding API, and compute Haversine distances both between stores of the same franchise and between stores of different franchises. This novel approach leads to three discoveries. First, coffee-consuming age population is positively related to the number of stores and more strongly for commercial areas with a large floating population. Second, one third of Starbucks stores have another Starbucks store within a radius of 300m, which empirically confirms the 'Focused Destroy Strategy' of Starbucks that has multiple stores in central business districts. Third, for 80% of Starbucks stores, we can find Ediya stores within 500m, which supports Ediya's 'Next-to-Starbucks Strategy'. Our research methods can be efficiently applied to the analyses of other retail businesses such as convenience stores, fast food restaurants, and mobile phone shops.