• Journal of Korean Neurosurgical Society
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• v.48 no.5
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• pp.412-418
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• 2010

Objective : To evaluate the clinical and radiological outcomes of lumbar interbody fusion and its correlation with various factors (e.g., age, comorbidities, fusion level, bone quality) in patients over and under 65 years of age who underwent lumbar fusion surgery for degenerative lumbar disease. Methods : One-hundred-thirty-three patients with lumbar degenerative disease underwent lumbar fusion surgery between June 2006 and June 2007 and were followed for more than one year. Forty-eight (361%) were older than 65 years of age (group A) and 85 (63.9%) were under 65 years of age (group B). Diagnosis, comorbidities, length of hospital stay, and perioperative complications were recorded. The analysis of clinical outcomes was based on the visual analogue scale (VAS). Radiological results were evaluated using plain radiographs. Clinical outcomes, radiological outcomes, length of hospital stay, and complication rates were analyzed in relation to lumbar fusion level, the number of comorbidities, bone mineral density (BMD), and age. Results : The mean age of the patients was 61.2 years (range, 33-86 years) and the mean BMD was -2.2 (range, -4.8 to -2.8). The mean length of hospital stay was 15.0 days (range, 5-60 days) and the mean follow-up was 23.0 months (range, 18-30 months). Eighty-five (64.0%) patients had more than one preoperative comorbidities. Perioperative complications occurred in 27 of 133 patients (20.3%). The incidence of overall complication was 22.9% in group A, and 18.8% in group B but there was no statistical difference between the two groups. The mean VAS scores for the back and leg were significantly decreased in both groups (p < 0.05), and bony fusion was achieved in 125 of 133 patients (94.0%). There was no significant difference in bony union rates between groups A and B (91.7% in group A vs. 95.3% in group B, p = 0.398). In group A. perioperative complications were more common with the increase in fusion level (p = 0.027). Perioperative complications in both groups A (p = 0.035) and B (p = 0.044) increased with an increasing number of comorbidities. Conclusion : Elderly patients with comorbidities are at a high risk for complications and adverse outcomes after lumbar spine surgery. In our study, clinical outcomes, fusion rates, and perioperative complication rates in older patients were comparable with those in younger populations. The number of comorbidities and the extent of fusion level were significant factors in predicting the occurrence of postoperative complications. However, proper perioperative general supportive care with a thorough fusion strategy during the operation could improve the overall postoperative outcomes in lumbar fusion surgery for elderly patients.

• Journal of Korean Academic Society of Home Health Care Nursing
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• v.5
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• pp.61-72
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• 1998

The purpose of this study was to identify the risk factors affecting home care patients 65 years of age and older with symptoms of depression. The author conducted this study for 80 depressed and non-depressed who were taking home care. Data was colleted from November 1996 to October 1997. The major findings of this study were as follows. Significant mean group differences were found on age and income in old home care patients with symptoms of depression, compared with non -depressed. Old home care patients who have less than 300,000won of income, smoking, exercise, unsatisfactory of home care, living in saparateness, rent, living alone, unbalanced diet, irregular diet were statistically significant risk factors by logistic regression. Old home care patients who do not exercise, less than 300,000won of income, unsatisfactory of home care, smoking, living alone were the risk factors by final logistic regression model predicting depression.

• Journal of the Korean Orthopaedic Association
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• v.55 no.1
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• pp.38-45
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• 2020

Purpose: To examine the clinical and structural outcomes of an at least two-year follow-up of arthroscopic full-thickness rotator cuff repairs with a single-row or suture-bridge technique in patients more than 65 years of age. Materials and Methods: Patients diagnosed with a full-thickness rotator cuff tear who were more than 65 years of age, underwent arthroscopic rotator cuff repair after at least six months of conservative treatment, agreed to take a follow-up magnetic resonance imaging (MRI) six months postoperatively, and visited outpatient for at least two years were enrolled in this study. Clinical evaluations were done using The University of California Los Angeles score, Constant Shoulder Score, and visual analogue scale evaluated two years after the surgery. The structural integrity was analyzed using follow-up MRI. During surgery, a suture-bridge technique was used if the rotator cuff tendon could cover half of the footprint under constant tension. Otherwise, single-row repair was performed. Results: The samples were 158 cases, consisting of 93 single-repairs and 65 suture-bridge repairs. A preoperative comparison of the age distribution, fatty degeneration of supraspinatus and infraspinatus muscle, medial retraction of torn cuff tendon, and tear size between the two groups were not significant. The clinical scores were improved significantly in all cases. The distribution of the structural integrity by Sugaya classification were 49 cases in type 1 (31.0%), 62 cases in type 2 (39.2%), 30 cases in type 3 (19.0%), 11 cases in type 4 (7.0%), and six cases in type 5 (3.8%). The re-tear rate of the single-row group was 9.7% (nine out of 93 cases) and 12.3% (eight out of 65 cases) for the suture-bridge group. Conclusion: Satisfactory clinical and radiological outcomes were achieved after arthroscopic full-thickness rotator cuff repair in patients more than 65 years of age. Both single-row and suture-bridge techniques would be beneficial for the elderly.

• Journal of Nutrition and Health
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• v.53 no.2
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• pp.155-174
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• 2020

Purpose: The purpose of this study was to investigate the effects of nutrient intake and dietary diversity score (DDS) on osteoporosis after controlling for sex, age, socioeconomic level, drinking, smoking, physical activity, and body mass index (BMI) as mediators using the 2015-2017 Korean National Health and Nutrition Examination Survey (KNHANES) data. Methods: This study was focused on the age group of 50s and older by using the 2015-2017 KNHANES data. Subjects diagnosed with osteoporosis were classified as the osteoporosis group, and the other subjects were classified as the normal group. Logistic regression was used to assess the association between nutrient intake and DDS after controlling for mediators. Results: The risk of osteoporosis was 2.38 times lower in the 50-65 age group than in the 75 years and older group. The mediators affecting the incidence of osteoporosis by age group were sex, age, household income level, and education level in the 50-64 age group; sex, education level, drinking, and BMI in the 65-74 age group; and sex, age, current smoking, drinking, BMI, and energy intake in the 75 years and older group. The effect of nutrient intake on osteoporosis, with the exception of vitamin B1, was fully mediated by these mediators. The effect of vitamin B1 was partially mediated by mediators in the age group of 65-74 years, and vitamin B1 was effective for preventing the risk of osteoporosis by 25% when consumed over EAR. The effect of DDS was partially mediated in the age group of 75 years and older, and DDS of 2 or less increased the risk of osteoporosis by 2.59 times. Conclusion: As a result of this study, it is necessary to recommend the balanced intake of various foods including grains, meat·fish·legumes, vegetables, fruits, and dairy products as dietary guidelines for the prevention of osteoporosis and promotion of bone health in the elderly.

• Journal of The Korean Society of Clinical Toxicology
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• v.16 no.2
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• pp.116-123
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• 2018

Purpose: The social environment of easy access to medicines and arbitrary personal decisions leading to overdose aggravate unintentional medicine poisoning. This study aimed to investigate the characteristics of patients who visited emergency departments with unintentional medicine poisoning and reasons for poisoning based on age group. Methods: We retrospectively collected patients who experienced unintentional medicine poisoning based on data from the national injury surveillance system between 2013 and 2016. Subjects were classified into three groups based on age (0-14 years, 15-64 years, and ${\geq}65\;years$). We identified sex, insurance, time of poisoning, place, alcohol co-ingestion, hospitalization, death, and reason for poisoning in each age group. Results: A total of 27,472 patients visited an emergency department with poisoning during the study period; 1,958 patients who experienced unintentional poisoning were enrolled in this study. Respiratory medicine was the most frequent medicine in those younger than 15 years of age, and sedatives and antipsychotic drugs were the most common in patients older than 15 years of age. In total, 35.1% of patients older than 65 years were hospitalized. The most common reasons for poisoning were careless storage of medicine in those younger than 15 years of age and overdose due to arbitrary decisions in those older than 15 years of age. Conclusion: Unintentional medicine poisoning has distinct characteristics based on age group, and strategies to prevent poisoning should be approached differently based on age.

• The Korean Journal of Food And Nutrition
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• v.34 no.1
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• pp.96-106
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• 2021

The purpose of this study was to compare the differences in the quality of dietary and life across age groups of Korean adults. According to life cycle, four age groups (20~29, 30~49, 50~64, ≥65) were created. Anthropometric indices showed significant differences according to age group (p<0.001). Energy intake significantly decreased according to age group as a result of decreased protein and fat intake (p<0.001). The intake levels of minerals, vitamins, and dietary fiber per 1,000 kcal were the lowest in the 20~29 age group (p<0.001). Whereas saturated fatty acids, MUFA, and PUFA intake levels were the highest for those in the 20~29 age group (p<0.001). The quality of dietary (DQI-I) increased with age group, but the quality of life (EQ-5D index) decreased (p<0.001). The quality of dietary showed 5.8% explanation power on the quality of life (p<0.001). Additionally, diet moderation was shown as having a negative effect, but the diversity and balance of diets had a positive effect on the quality of life. By age group, the relationship between quality of dietary and quality of life was the highest in ≥65 age group. These results suggest that practical dietary education is needed from the 20's to ensure the quality of healthy life for the elderly.

• Journal of Menopausal Medicine
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• v.24 no.3
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• pp.176-182
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• 2018

Objectives: Menopause is associated with adverse metabolic changes in plasma lipoprotein and inflammation markers. Estrogens have beneficial effects on lipid metabolism and inflammation. Isoflavones (ISO) have structurally similar to estradiol. Our objective was analize the effect of soy-ISO on serum lipid and inflammatory markers (sP-selectin and sCD40L) in postmenopausal women. Methods: A 12-week randomized, double-blind, placebo-controlled intervention with soy-ISO (50 mg, twice daily) was conducted in 35 healthy postmenopausal women (55-72 years old). The women were divided in 2 groups: 20 were allocated to soy-ISO, and 15 to a placebo group. Results: The changes of total cholesterol (TC), triglycerides, low-density lipoproteins-cholesterol (LDL-C), high-density lipoprotein-cholesterol, Apo-A1, sP-selectin and sCD40L in 2 groups before and after 12-week treatment showed no statistical significance. In subgroup analysis, soy-ISO supplementation significantly decreased the levels of TC, LDL-C and sCD40L in women under 65 years old, and with null effects on serum lipid and inflammation markers in women over 65 years old. Conclusions: Soy-ISO did not significantly favorable effects on the lipid profile and inflammatory markers in postmenopausal women. However, in women under 65 years of age, soy-ISO significantly decreased the TC, LDL-C and sCD40L, whereas, no effects on lipid profile and inflammation markers in women over 65 years old were observed.

• 한국노년학
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• v.39 no.4
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• pp.977-996
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• 2019

The current study aimed to examine the gender differences in trajectories of nine successful aging indicators (chronic disease, depression, activities of daily living, instrumental activities of daily living, mini mental state examination, social activity, personal contact, health satisfaction, and general life satisfaction) with age, controlling the effect of education. The data were from the Korean Longitudinal Study of Aging, which had been conducted biennially from 2006 to 2016. The sample included 822 men and 1,236 women who responded to all of the panel surveys and were 65 years old or above in 2006. Multilevel modeling analyses showed that older men had fewer chronic diseases; lower levels of depression; higher levels of activities of daily living, cognitive function, and social activity; and better perceived health satisfaction and general life satisfaction at age 65 years compared to women. However, both men and women showed increase in the number of chronic diseases and depression level, and decrease in physical, cognitive, and social functions with age. In addition, perceived health and life satisfaction also decreased after the age of 65. The trajectories of most of the indicators were non-linear, and markedly increased or decreased around mid-70s. Study limitations and implications were further discussed.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.7
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• pp.3647-3650
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• 2016

Background: Colorectal cancer is one of the major health problems worldwide. However, limited studies have been reported from ASEAN countries. This study was conducted to evaluate clinical characteristics and survival of colorectal cancer cases aged <65 years and ${\geq}65$ years in the central region of Thailand. Materials and Methods: Clinical information, histological features, endoscopic findings and treatment outcome were collected and reviewed from Thammasat University Hospital, Pathumthani, Thailand between November 2011 and October 2015. Results: A total of 121 colorectal cancer patients, comprising 69 men and 52 women with a mean age of 65.8 years, were included. There were 57 aged <65 years and 64 aged ${\geq}65$ years. Common presenting symptoms were abdominal pain (37%), weight loss (34%) and anemia (32%). Mean duration of symptoms prior to diagnosis was 173 days. However, longer diagnosis time was demonstrated in patients aged <65 years than age more than ${\geq}65$ years (119.4 vs 58.4 days, P-value=0.30). Colonic fungating mass was the most common endoscopic finding (64.4%) and the location was significantly more commonly left than right side of the colon, both in younger and elderly groups (87.7% vs 12.3%, P=0.02 and 70.3% vs 29.7%, P=0.02, respectively). Adenocarcinoma with moderated differentiated was the most common histology (67.3%). More than half of the patients presented with advanced stage (28.9% with TNM stage 3 and 38.8% TNM stage 4, respectively). Overall 1-year and 5-year survival rates were 76.9% and 5%. Conclusions: Most colorectal cancer patients in Thailand have adenocarcinomas and present at advanced stage with poor prognosis. Screening of high risk patients and early detection might be essential factors to improve the treatment outcome and overall survival rate of colon cancer patients in Thailand and other ASEAN countries.

• Journal of the East Asian Society of Dietary Life
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• v.16 no.4
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• pp.387-398
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• 2006

The purpose of this study was to compare the nutritional meal variety of self-selected diet in Korean adults with different age groups. Subjects were recruited and divided info three groups according to the age, which included 20$\sim$49 yrs group(n=129), 50$\sim$64 yrs group(n=134), and $\geq$65 yrs group(n핀8). Subjects were interviewed using a general questionnaire and 24-hour recall method for dietary intake. The average age of the subjects were 40.8 years for 20$\sim$49 yrs group, 57.1 years for 50$\sim$64 yrs group, and 70.7 years for $\geq$65 yrs group. The daily food, energy and nutrient intakes ere decreased with increment of age. The intakes of vitamin B2, folate, vitamin C, and calcium were under the 75% of RIs, respectively. The numbers of food items in diet of 20$\sim$49 yrs group, 50$\sim$64 yrs group and $\geq$65 yrs group were 14.2, 17.0, 13.2 for breakfast, 16.3, 15.4, 13.5 for lunch, 13.1, 15.1, 13.9 for dinner, respectively. And the numbers of dish items in these groups were 4.0, 4.6, 3.8 for breakfast, 4.4, 4.2, 3.9 for lunch, 4.0, 4.0, 3.6 for dinner, respectively. The KDDS of 20$\sim$49 yrs group, 50$\sim$64 yrs group and $\geq$65 yrs group were 3.9, 3.6 and 3.4 respectively and there was significant difference(p<0.001). According to these results, it could be suggested aged group take a undesirable meal in the right of insufficient nutrient intake to DRIs and lower food and dish items, and therefore showing a strong need of proper dietary management for them.