• Title/Summary/Keyword: Aflatoxin

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Control of Aflatoxin and Characteristics of the Quality in Doenjang(soybean paste) Prepared with Antifungal Bacteria (길항미생물에 의한 된장 중 아플라톡신 제어 및 그 품질특성)

  • Kang, Kil-Jin;Park, Jong-Hoon;Cho, Jung-Il
    • Korean Journal of Food Science and Technology
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    • v.32 no.6
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    • pp.1258-1265
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    • 2000
  • In oder to acquire microbial agents that can be utilized for control of aflatoxin produced by Aspergillus. flavus and Asp. parasiticus, antifungal bacteria were isolated. Antifungal bacteria was identified as Bacillus spp. based on morphology and physico-biochemical characteristics. Amount of aflatoxin $B_1$ from Doenjang(soybean paste) prepared with Asp. flavus, Asp. parasiticus, antifungal bacteria(Bacillus sp.), or mixture of Asp. flavus and Asp. parasiticus was 27.2 ppb, 30.3 ppb, 3.4 ppb, and 3.7 ppb, respectively. Aflatoxin $B_1$ was not detected from Doenjang(control) and Doenjang prepared with antifungal bacteria. Content and compositions of free sugars, fatty acid, organic acid and free amino acid in Doenjang prepared with Asp. flavus and Asp. parasiticus, antifungal bacteria and mixture of Asp. flavus and Asp. parasiticus were not significantly different. For volatile flavor compounds of Doenjang prepared with antifungal bacteria, 2-pentyl furan and butanoic acid were disappeared or reduced, while octadecene compounds were produced. However, those of Doenjang prepared with Asp. flavus or Asp. parasiticus and Doenjang(control) were not significantly different. These results suggested that the antifungal bacteria(Bacillus sp.) inhibited production of aflatoxin and that antifungal bacteria did not effect the quality of Doenjang.

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Studies on the Toxin Productivity of Fungi in Cereals (진균주의 독소생산능에 관한 연구)

  • Ryeom, K.;Lee, J.H.
    • Environmental Analysis Health and Toxicology
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    • v.1 no.1
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    • pp.71-76
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    • 1986
  • The determination of fungal flora in some kinds of cereals have been carried out in other to obtain an appropriate information of the population of fungi and toxin productivity The results were summarized as follow; 1. The predominant genera were Aspergillus, Penicillium, Mucor, Rhizopus, Alternaria, Fusarium. 2. Six of Aspergillus flavus were aflatoxin-producing strains. 3. Sample barleys were found to contain the highest content of aflatoxin. 4. In electron microscopic studies of liver cells from mouse which had been injected with crude toxin, the liver cells showed the cytoplasmic change.

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Effect of Allylisothiocyanate on the Enzyme Activities During the Culture of Aspergillus parasiticus R-716 (Allylisothiocyanate첨가가 Aspergillus parasiticus R-716의 배양중 효소활성에 미치는 영향)

  • 김성영
    • Journal of Food Hygiene and Safety
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    • v.12 no.2
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    • pp.97-101
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    • 1997
  • Effect of allylisothiocyanate on the enzyme activites including malate degydrogenase, isocitrate dehydrogenase, NADPH and acetyl CoA which were related to aflatoxin production of Aspergillus parasticus R-716 were invetigated. The activities of malate dehydrogenase (EC.1.1.1.37), isocitrate dehydrogenase (E.C.1.1.1.42) and NADPH oxidase (E.C.1.6.99.1) indicated relatively high in the 50 ppm allylisothiocyanate-added-culture. In contrast, the activity of acetyl CoA in the 50 ppm allylisothiocyanate-added-culture showed rather lower level through the cultivation.

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Studies on the Safety of Korean Ginseng and Ginseng Products (韓國産 人蔘 및 人蔘製品의 安全性에 關한 연구)

  • Noh, Wan Seob;Oh, Hyun Kun;Kwon, Dae Won;Lee, Kwang Seung
    • Journal of Environmental Health Sciences
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    • v.10 no.1
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    • pp.93-98
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    • 1984
  • In order to survey the distribution of molds in Korean Ginseng and its products, molds were isolated from their sample to obtain 22 strains. Among them, 3 strains were found to produce aflatoxin and identified as Aspergillus flavus, Aspergillus paraciticus and Penicillium puberulum. The type of aflatoxin produce was identified as $B_1$, $B_2$ and $G_1$.

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Studies on Mycotoxins in Feed (사료내의 곰팡이 독소에 관한 연구)

  • Yoon Hwa-Joong;Chang Kyoung-Jin;Kim Tae-Jong
    • Journal of the korean veterinary medical association
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    • v.19 no.7
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    • pp.67-73
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    • 1983
  • Strains of Aspergillus flavus produced aflatoxin $B_1$ was found in the corns for eed and cultured them in the incubator. The aflatoxin $B_1$ was produced from the Aspergilli and intubated into the pharynx of the ducklings for the to

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Synthesis of 4,5-substituted 3-alkoxy-6-allylthiopyridazine Derivatives (4,5-치환 3-alkoxy-6-allylthiopyridazine 유도체 합성)

  • 권순경
    • YAKHAK HOEJI
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    • v.46 no.3
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    • pp.155-160
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    • 2002
  • Through a modification of allicin structure a disagreeable odor and chemical instability of allicin can be improved. 3-Alkoxy-6-allylthiopyridazine derivatives exhibit a superior effect for prevention and treatment of hepatic diseases induced by carbon tetrachloride and aflatoxin B1 and for prevention of human tissues from radiation. These compounds inhibit also efficiently SK-Hep-1 cell proliferation through induction of apoptosis. So another 4,5-mono- or di-substituted 3-alkyloxy-6-allylthiopyridazine derivatives were synthesized on purpose to find out SAR of allylthiopyridazine in hepatoprotective and hepatotherapeutic acitivitis and to develop more effective drug candidate.