• 제목/요약/키워드: Adverse conditions

검색결과 548건 처리시간 0.024초

Development of a predictive model for hypoxia due to sedatives in gastrointestinal endoscopy: a prospective clinical study in Korea

  • Jung Wan Choe;Jong Jin Hyun;Seong-Jin Son;Seung-Hak Lee
    • Clinical Endoscopy
    • /
    • 제57권4호
    • /
    • pp.476-485
    • /
    • 2024
  • Background/Aims: Sedation has become a standard practice for patients undergoing gastrointestinal (GI) endoscopy. However, considering the serious cardiopulmonary adverse events associated with sedatives, it is important to identify patients at high risk. Machine learning can generate reasonable prediction for a wide range of medical conditions. This study aimed to evaluate the risk factors associated with sedation during GI endoscopy and develop a predictive model for hypoxia during endoscopy under sedation. Methods: This prospective observational study enrolled 446 patients who underwent sedative endoscopy at the Korea University Ansan Hospital. Clinical data were used as predictor variables to construct predictive models using the random forest method that is a machine learning algorithm. Results: Seventy-two of the 446 patients (16.1%) experienced life-threatening hypoxia requiring immediate medical intervention. Patients who developed hypoxia had higher body weight, body mass index (BMI), neck circumference, and Mallampati scores. Propofol alone and higher initial and total dose of propofol were significantly associated with hypoxia during sedative endoscopy. Among these variables, high BMI, neck circumference, and Mallampati score were independent risk factors for hypoxia. The area under the receiver operating characteristic curve for the random forest-based predictive model for hypoxia during sedative endoscopy was 0.82 (95% confidence interval, 0.79-0.86) and displayed a moderate discriminatory power. Conclusions: High BMI, neck circumference, and Mallampati score were independently associated with hypoxia during sedative endoscopy. We constructed a model with acceptable performance for predicting hypoxia during sedative endoscopy.

KSUPRAMAX 모형선의 장파정 불규칙파 중 전진속도 및 선회궤적을 유사 재현하는 규칙파 탐색 (Forward Speeds and Turning Trajectories of a KSUPRAMAX Model Ship in Long-Crested Irregular and Equivalent Regular Waves)

  • 김동진;윤근항;권창섭;김연규;황승현
    • 대한조선학회논문집
    • /
    • 제61권4호
    • /
    • pp.258-266
    • /
    • 2024
  • It is necessary to predict the ship's manoeuvrabilities in waves for its safe operations in adverse weather. At the early design stage, free-running model tests can be performed to estimate the ship's manoeuvring performance in irregular wave conditions. The wave elevations are randomly varied with times in irregular waves, large deviations of the manoeuvring performance indices are likely to occur depending on the start time of steering scenarios. In this study, a KSUPRAMAX model ship's manoeuvres in long-crested irregular waves are reproduced in the equivalent regular waves. The equivalent regular waves are searched from the energy flux relations between long-crested irregular and regular waves. But there are differences of forward speeds in the model tests, regular wave height and period are modified so that both the forward speed and the trajectory drift in regular waves are similar to those in irregular waves. In addition, low speed course-keeping tests are performed with various wave incident angles in irregular and regular waves. It is confirmed that check helms, drift angles, and speeds as well as trajectories in irregular waves are similar to those in equivalent regular waves.

Application of a traction metal clip with a fishhook-like device in wound sutures after endoscopic resection

  • Wang Fangjun;Leng Xia;Gao Yi;Shen Xiuyun;Wang Wenping;Liu Huamin;Liu Pengfei
    • Clinical Endoscopy
    • /
    • 제55권4호
    • /
    • pp.525-531
    • /
    • 2022
  • Background/Aims: Endoscopic wound suturing is an important factor that affects the ability to remove large and full-thickness lesions during endoscopic resection. We aimed to evaluate the effect of a traction metal clip with a fishhook-like device on wound sutures after endoscopic resection. Methods: From July 2020 to April 2021, patients who met the enrollment criteria were treated with a fishhook-like device during the operation to suture the postoperative wound (group A). Patients with similar conditions and similar size wounds who were treated with a "purse-string suture" to suture the wounds were retrospectively analyzed as the control group (group B). Difference in the suture rate, adverse events, time required for suturing, and number of metal clips were compared between the two groups. Results: The time required for suturing was 7.72±0.51 minutes in group A and 11.50±0.91 minutes in group B. This difference was statistically significant (F=13.071, p=0.001). The number of metal clamps used in group A averaged 8.1 pieces/case, and the number of metal clamps used in group B averaged 7.3 pieces/case. This difference was not statistically significant (F=0.971, p=0.331). Conclusions: The traction metal clip with the fishhook-like device is ingeniously designed and easy to operate. It has a good suture effect on the wound after endoscopic submucosal dissection and effectively prevents postoperative adverse events.

플라스틱 소재의 탈변색 열화 메커니즘 분석 (A Study for Degradation Mechanism of Plastic Materials)

  • 윤형준;정원욱;변두진;최기대
    • 한국신뢰성학회지:신뢰성응용연구
    • /
    • 제7권4호
    • /
    • pp.173-181
    • /
    • 2007
  • Out door exposure to daylight and weather climate conditions can cause adverse effect on the properties of automotive plastic materials. The effects of sunlight exposure, especially ultra violet (UV) radiation, can break down the chemical bonds in a polymeric material. This degradation process is called photo-degradation and ultimately leads to color changes, cracking, chalking, the loss of physical properties and deterioration of other properties. To explore the effect of sunlight exposure on the automotive materials, this study investigated photo-oxidation degree and surface property change of molding parts by analytical methods. For the further study, accelerated weathering test methods are proposed, which can correlate with out door weathering, to predict long term performance of automotive plastic materials.

  • PDF

Ultrafine Particle의 독성, 측정방법 및 관리 (Ultrafine Particle Toxicities, Current Measurement Techniques and Controls)

  • 이수길;김성수
    • 한국산업보건학회지
    • /
    • 제20권3호
    • /
    • pp.203-215
    • /
    • 2010
  • This study is an overview of toxicities and measurement techniques of ultrafine particles (UFPs), and their exposure controls. UFPs are ubiquitous in many working situations. Exposure to UFPs is possibly causing adverse health symptoms including cardio-respiratory disease to humans. In order to measure exposure levels of airborne UFPs, there are current available measurement guidelines, instruments and other techniques (i.e. contour mapping, control banding). However, these risk assessment techniques including measurement techniques, controls and guidelines are dependent on background levels, metrics (e.g. size, mass, number, surface area, composition), environmental conditions and controls. There are no standardized measurement methods available and no generic and specific occupational exposure standards for UFPs. It is thought that there needs to be more effort to develop Regulations and Exposure Standards for generic UFPs should be based on more exposure data, health surveys, toxicological data and epidemiological data. A carefully considered hierarchy of controls can also reduce the maximum amount of airborne UFPs being emitted from diverse sources in industries.

공력에 의한 HEMU-400x 고속열차의 주행안정성 평가 (Stability Evaluation on Aerodynamics of High Speed Railway Train)

  • 최지훈;박태원;심경석;곽민호;이동호
    • 한국소음진동공학회논문집
    • /
    • 제22권3호
    • /
    • pp.244-252
    • /
    • 2012
  • Recently, the speed of a train has been increased. So the trains are being exposed to wind more severely than before. Because of the operation of high speed trains and lightweight of the train, risks of train derailment have being increased. In this study, aerodynamic effects of a newly designed high speed train, HEMU-400x, are evaluated. For aerodynamic effect evaluation, analysis method is selected by examining the safety standards for high speed train. The condition of aerodynamic effects is selected by adverse effect conditions. In order to calculate $C_s$ coefficients, numerical analysis is conducted. Using $C_s$ coefficients, the side force is calculated. Through dynamics analysis, derailment and wheel unloading are obtained. Using these results, derailment evaluation is performed.

Human Mental Condition Monitoring through Measurement of Physiological Signals

  • Ulziibayar, Natsagdorj;Kang, Sanghoon;Park, Hanhoon
    • 한국멀티미디어학회논문지
    • /
    • 제23권9호
    • /
    • pp.1147-1154
    • /
    • 2020
  • Nowadays, one of the most common diseases is chronic mental fatigue syndrome. This can be caused by many factors, such as busy life, heavy workload, high population density, and adverse technological impact. Most office workers and students who are sitting all day long while being exposed to this kind of environments are likely to be involved in the mental illness. Therefore, to prevent the illness, it has been highly required to design a device that enables mental fatigue to be monitored continuously without human intervention. This paper proposes a linear regression method to reliably estimating the level of human mental fatigue using wearable physiological sensors, with an estimation error of 0.852. Also, this paper presents an Android application that is able to check mental health conditions in daily life.

TEMPORAL AND SPATIO-TEMPORAL DYNAMICS OF A MATHEMATICAL MODEL OF HARMFUL ALGAL INTERACTION

  • Mukhopadhyay, B.;Bhattacharyya, R.
    • Journal of applied mathematics & informatics
    • /
    • 제27권1_2호
    • /
    • pp.385-400
    • /
    • 2009
  • The adverse effect of harmful plankton on the marine ecosystem is a topic of deep concern. To investigate the role of such phytoplankton, a mathematical model containing distinct dynamical equations for toxic and non-toxic phytoplankton is analyzed. Stability analysis of the resulting three equation model is carried out. A continuous time variation in toxin liberation process is incorporated into the model and a stability analysis of the resulting delay model is performed. The distributed delay model is then extended to include the spatial distribution of plankton and the delay-diffusion model is analyzed with spatial and spatiotemporal kernels. Conditions for diffusion-driven instability in both the cases are derived and compared to explore the significance of these kernels. Numerical studies are performed to justify analytical findings.

  • PDF

비피도박테리아의 생존성 증진을 위한 캡슐화 기술 (Microencapsulation Technology for Enhancement of Bifidobacterium spp. Viability: A Review)

  • 송민유;박원서;유자연;함준상
    • Journal of Dairy Science and Biotechnology
    • /
    • 제35권3호
    • /
    • pp.143-151
    • /
    • 2017
  • The intestinal microbiota has been shown to have a vital role in various aspects of human health, and accumulating evidence has shown the beneficial effects of supplementation with bifidobacteria for the improvement of human health, ranging from protection against infection to various positive effects. However, maintaining bacterial cell viability during storage and gastrointestinal transit remains a challenge. Microencapsulation of probiotic bacterial cells provides protection against adverse conditions during processing, storage, and gastrointestinal passage. In this paper, we review the current knowledge, future prospects, and challenges of microencapsulation of probiotic Bifidobacterium spp.

직무분석을 통한 회전익 항공기 조종사 적성에 관한 연구 (A Study on Aptitude for Helicopter Pilots through the Job Analysis)

  • 유태정;김칠영
    • 한국항공운항학회지
    • /
    • 제14권1호
    • /
    • pp.63-69
    • /
    • 2006
  • The operational environment of helicopters extends from the civil air traffic control system to remote and hazardous areas and from day operations under visual flight conditions to night operations in adverse weather. Helicopters can move in any direction, remain stationary while airborne, climb and descend vertically, and take off and land almost anywhere. Thus their range of maneuvers and control requirements vary more widely than do those of fixed-wing aircraft. In this study, I analyzed the job of helicopter pilot through methods of observation, and classified the required ability of them into the domain of cognitive, perceptual/spatial, psychomotor. I expect that the result of this study will be used to aid training and selection of helicopter pilot.

  • PDF