• 약학회지
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• 제51권5호
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• pp.318-326
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• 2007

The elderly are more likely to have chronic medical conditions that require multiple drug therapies. Purposes of this study are to reveal necessity of elderly patient education by pharmacists, and to induce appropriate policy. We carried out literature research. Taking several drugs together increases risk of drug interactions and adverse reactions. We suggest that pharmacists have the legal authority to monitor prescription for efficient drug management, pharmacovigilance system be efficiently operated, and medication education fee be provided to allow pharmacists give more time to the elderly.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 1996년도 봄 학술발표회 논문집
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• pp.348-353
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• 1996

This study addresses the evaluation of the durability of reinforced concrete marine structures subjected to fatigue loading. The laboratory investigation was carried out on full and half size reinforced concrete specimens with three different water cement ratios (0.3, 0.4, and 0.56), static and fatigue loading conditions, and epoxy-coated and regular black steel reinforcements. The marine tidal zone was simulated by alternate filling and draining of the tank (wet and dry cycled), and a galvanostatic corrosion technique to accelerate corrosion of reinforcement was used. Half-cell potentials and changes of crack width were measured periodically during the exposure and followed by ultimate strength testing. The significant findings include adverse effect of fatigue loading, existence of an explicit size effect, poor performance of epoxy coated steel, and negative effect of increasing water/cement ratio.

• 한국해양공학회지
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• 제19권6호통권67호
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• pp.1-7
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• 2005

This paper deals with the design and aerodynamic analysis of a special-type impulse turbine, with an end plate for wave energy conversion. Numerical analysis was performed using a CFD code, FLUENT. The main idea of the proposed end plate was to minimize the adverse effect of tip clearance of turbine blade, and was borrowed from ducted propeller, with so-called penetrating end plate for special purpose marine vehicles. Results show that efficiency increases up to $5\%$, depending on the flow coefficient; a higher flow coefficient yields increased efficiency. Decrease of input coefficient CAwith an end plate is the main reason for higher efficiency. Performance of end plate at various design parameters, as well as flow conditions, was investigated; the advantages and disadvantages of the presentimpulse turbine were also discussed.

• Asian-Australasian Journal of Animal Sciences
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• 제13권8호
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• pp.1133-1136
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• 2000

Wheat straw was treated with 4 per cent urea at a moisture level of 50 per cent alongwith different levels of boric acid viz. 1, 2, 3 and 4 per cent, under laboratory conditions to know the impact of boric acid on ammonia-N fixation in the straw. Murrah buffaloes were used for determining the disappearance of dry matter, CP and fibre constituents by nylon bag technique. Ammoniation increased CP content of wheat straw, which increased further due to addition of boric acid. Low level of boric acid (1%) had no adverse effect on fibre constituents disappearance but at higher levels there was a depressioon in the disappearance of fibre coonstituents. It can be concluded that low level of boric acid was sufficient to trap the excess ammonia released during urea ammoniation of wheat straw without affecting other constituents and their disappearance in the rumen of buffaloes.

• 한국국방경영분석학회지
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• 제24권1호
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• pp.132-145
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• 1998

The seakeeping performance can be defined as the ability of a ship to go to sea, and successfully and safely execute its missions even in adverse environmental conditions. From the viewpoint of safe operation, it is primarily important to estimate the seakeeping performance of a ship in a seaway. A method of evaluating navigational safety is presented by means of the integrated seakeeping performance index(ISPI) by measuring only vertical acceleration. Judgement of dangerousness is carried out for two types of naval vessels in applying the involuntary speed losses. The used models for computer simulation are Lpp 175m light aircraft carrier and Lpp 93m frigate. In developing the practical evaluation system of navigational safety, it is expected to be useful to solve the difficulties in measuring factors by sensors. The results are also useful for developing the optimum type of naval vessels by applying at the initial design phase.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제18권4호
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• pp.286-291
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• 2015

Ulcerative colitis (UC) is a chronic idiopathic inflammatory bowel disease. Mesalizine for the first-line therapy of UC has adverse effects include pancreatitis, pneumonia and pericarditis. UC complicated by two coexisting conditions, however, is very rare. Moreover, drug-related pulmonary toxicity is particularly rare. An 11-year-old male patient was hospitalized for recurring upper abdominal pain after meals with vomiting, hematochezia and exertional dyspnea developing at 2 weeks of mesalizine therapy for UC. The serum level of lipase was elevated. Chest X-ray and thorax computed tomography showed interstitial pneumonitis. Mesalizine was discontinued and steroid therapy was initiated. Five days after admission, symptoms were resolved and mesalizine was resumed after a drop in amylase and lipase level. Symptoms returned the following day, however, accompanied by increased the serum levels of amylase and lipase. Mesalizine was discontinued again and recurring symptoms rapidly improved.

• 한국초지조사료학회지
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• 제17권1호
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• pp.35-42
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• 1997

Many farmers apply cattle slurry on grassland, often in excess of crop N requirements, resulting in groundwater contamination. Our research objective was the development of grassland management systems that reduce undesirable sideeffects on other compartment of the ecosystem. Field experiment was conducted during 1991~1993 on sandy loam soil at AllgZiu south western Germany. Different sets of conditions were tested such as : zero fertilization, reduced sluny application$(l20kg N ha^{-1}yr^{-1})$, intensive sluny application(conventional sluny application, $240kg N ha^{-1}yr^{-1}$). The plots of the reduced slurry application had no significant effect on dry matter yields, digestible dry matter and net energy of herbage. Dry matter yield of zero fertilization was significantly lower than that of usual slurry application, however the content of Ca and Mg in herbage tended to increase. We conclude that reduced sluny application can be applied on grassland without adverse effects on dry matter production and quality of herbage.

• 대한불안의학회지
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• 제1권1호
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• pp.37-42
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• 2005

Benzodiazepines are widely used for a variety of conditions in psychiatric field. In this article, the author reviewed the indications, the effects on anxiety and sleep disorders, the side effects, the drug-drug interactions, and the tapering strategies. Benzodiazepines were relatively safe and useful for the treatment of anxiety and sleep disorders. However, used clinically, benzodiazepines can induce many adverse effects (e. g. over-sedation, cognitive impairments, paradoxical effects, dependence and withdrawal symptoms, and so on). Currently available informations about their effects on the developing fetus is controversial. For this reason, pregnant women and nursing mother should be cautioned against the use of benzodiazepines. Drug-drug interactions have to be considered in combination treatments. For the tapering issues, gradual tapering was important to prevent the withdrawal symptoms. Especially, the tapering schedules have to be individualized for the each long-term benzodiapzepine users.

• 한국항공운항학회지
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• 제22권3호
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• pp.1-7
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• 2014

The base of leisure air activities are consistently expanding and its demand is expected to increase attributed to GDP growth and people's interest in its activity. Utilizing Visual Flight Rule, light sport aircrafts and ultra-light aircrafts are not under the effect of air traffic control center, which resulted in passenger injury due to emergency landing for adverse weather conditions and technical issues after pulling into mountain area, ocean and even urban area. Such events encouraged safety consciousness toward leisure aircraft activities and developing a measure to prevent a recurrence of the accident. This research focuses on suggesting compositive system for preventive safety management system by providing user based Flight information service and operating effective system, necessary for leisure aircraft activities.

• 말소리와 음성과학
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• 제3권3호
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• pp.141-148
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• 2011

There are many factors that affect speech intelligibility and speech acceptability. Structural anomalies and neuromotor pathologies are known for the reasons of abnormal speech sounds. And there are minor variations related to oral mechanism. Speaking with restricted mouth opening related to therapeutic procedure or habitual speech pattern might affect the quality of speech sounds. So this study compared speech intelligibility and speech acceptability of recorded 24 words in two conditions (restricted mouth opening condition and normal mouth opening condition) by 30 normal hearing adults. The results showed that speech intelligibility and speech acceptability were significantly lower in restricted mouth opening condition. And speech acceptability was significantly lower than speech intelligibility in restricted mouth opening condition. Speech acceptability in restricted mouth opening condition was significantly lower especially in open vowel. These findings indicated that the mouth opening condition could affect vowel shape and could be an adverse effect on speech intelligibility and speech acceptability.