• Development and Reproduction
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• v.24 no.1
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• pp.1-17
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• 2020

Phthalates and those metabolites have long history in industry and suspected to have deficient effects in development and reproduction. These are well-known anti-androgenic chemicals and many studies have examined the effects of these compounds on male reproduction as toxins and endocrine disruptors. Uterus is a key organ for proper embryo development, successful reproduction, and health of eutherian mammals including women. To understand the effects of the phthalate, the horizontal approach with a whole group of phthalate is best but the known phthalates are huge and all is not uncovered. Di-(2-ethylhexyl) phthalate (DEHP) is the most common product of plasticizers in polymer products and studied many groups. Although, there is limited studies on the effects of phthalates on the female, a few studies have proved the endocrine disrupting characters of DEHP or phthalate mixture in female. An acute and high dose of DEHP has adverse effects on uterine histological characters. Recently, it has been revealed that a chronical low-dose exposing of DEHP works as endocrine disrupting chemicals (EDC). DEHP can induce various cellular responses including the expression regulation of steroid hormone receptors, transcription factors, and paracrine factors. Interestingly, the response of uterus to DEHP is not monotonous and the exposed female has various phenotypes in fertility. These suggest that the exposing of DEHP may causes of histological modification in uterus and of disease in female such as endometriosis, hyperplasia, and myoma in addition to developmental and reproductive toxicity.

• The Journal of Asian Finance, Economics and Business
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• v.5 no.2
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• pp.35-42
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• 2018

In recent decades, financial crises in various countries have often been preceded by the rise in non-performing loans (NPLs) in the banks' asset portfolios. The increase in NPLs is proven to have adverse impact on the banking sector so that understanding the determinant of NPLs is immensely crucial to ensure the efficiency and soundness of the overall economy. This study aims to shed light on bank-specific factors that affect loan default problems in developing countries whose banking sectors play a major role in the overall economy. This study analyzes panel data sets of 36 commercial banks listed in the Indonesian Stock Exchange during the period 2008-2015. Applying fixed-effects panel regression model reveals that Indonesian banks' profitability and credit growth negatively influence the number of NPLs. Moreover, banks with higher profitability are proven to have lower NPLs because they can afford adequate credit management practices. Likewise, banks with higher credit growth evidently have lower NPLs in the sense that they demonstrate more specialized lending activity and thus have better credit management systems. These findings imply that, in order to lower loan defaults that can deteriorate banks' asset quality, banks should maintain their level of profitability and increase, rather than decrease, their credit supply to debtors.

• Journal of Aquaculture
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• v.18 no.3
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• pp.196-199
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• 2005

Farmed red sea breams, Pagrus major, were fed for 60 days with pellets containing different concentrations of benzo(a)pyrene (0, 0.2, 2, 20 mg/kg) to generate a biomarker of the chemical toxicity in the fish. The fish exposed to the chemical concentrations did not show any significant difference in the weight gain, conditioning, factor, and hepatosomatic index. However, some haematological parameters, such as glucose, calcium, magnesium, GOT (glutamic oxalate transaminase), and GPT (glutamic pyruvate transaminase) were influenced by the chemical exposure. Of them, two enzymes, GOT and GPT, increased significantly 60 days after the exposure in a way of concentration dependence (P<0.05). In the study of ecotoxicological biomarker, sensitivity to adverse environments is one of the key available factors. The fish changes in GOT and GPT were an earlier and reliable sign of the fish response against the chemical exposure, rendering the two enzymatic factors as a useful biomarker at least to benzo(a)pyrene exposure in the farming waters.

• Journal of the Korean Home Economics Association
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• v.49 no.6
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• pp.67-83
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• 2011

The purposes of this study were to a develop a preventive tailored early intervention program and to investigate the effects of the program on the quality of parenting for low income families. The subjects were eighty five infants, aged 13 to 32 months, and their mothers. Of the 85 mother-infant dyads, 42 dyads were randomly assigned to the experimental group and 43 dyads to the control group. To prevent the risks of the adverse development of infants from low income families a tailored intervention program was created based upon the transactional model. This emphasized the quality of the home environment and of the daily mother-infant interaction. The risk factors were assessed and progress monitoring was undertaken for the preventive tailored intervention treatment. In order to assess the effects of the program, HOME, the NCAST Teaching Scale and the Parenting Stress Index/Short From were used. The collected data were analyzed with descriptive statistics, ANCOVA, and the McNemar test. The experimental group showed a significant increase in performance and higher scores than the control group on the scores from HOME, and the NCAST Teaching Scale and significant decrease and lower scores in the Parenting Stress Index(SF).

• Structural Monitoring and Maintenance
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• v.3 no.3
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• pp.277-296
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• 2016

There is a need for rapid and objective assessment of concrete bridge decks for maintenance decision making. Infrared Thermography (IRT) has great potential to identify deck delaminations more objectively than routine visual inspections or chain drag tests. In addition, it is possible to collect reliable data rapidly with appropriate IRT cameras attached to vehicles and the data are analyzed effectively. This research compares three infrared cameras with different specifications at different times and speeds for data collection, and explores several factors affecting the utilization of IRT in regards to subsurface damage detection in concrete structures, specifically when the IRT is utilized for high-speed bridge deck inspection at normal driving speeds. These results show that IRT can detect up to 2.54 cm delamination from the concrete surface at any time period. It is observed that nighttime would be the most suitable time frame with less false detections and interferences from the sunlight and less adverse effect due to direct sunlight, making more "noise" for the IRT results. This study also revealed two important factors of camera specifications for high-speed inspection by IRT as shorter integration time and higher pixel resolution.

• Safety and Health at Work
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• v.8 no.2
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• pp.206-211
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• 2017

Background: Self-reported low back pain (LBP) has been evaluated in relation to material handling lifting tasks, but little research has focused on relating quantifiable stressors to LBP at the individual level. The National Institute for Occupational Safety and Health (NIOSH) Composite Lifting Index (CLI) has been used to quantify stressors for lifting tasks. A chemical exposure can be readily used as an exposure metric or stressor for chemical risk assessment (RA). Defining and quantifying lifting nonchemical stressors and related adverse responses is more difficult. Stressor-response models appropriate for CLI and LBP associations do not easily fit in common chemical RA modeling techniques (e.g., Benchmark Dose methods), so different approaches were tried. Methods: This work used prospective data from 138 manufacturing workers to consider the linkage of the occupational stressor of material lifting to LBP. The final model used a Bayesian random threshold approach to estimate the probability of an increase in LBP as a threshold step function. Results: Using maximal and mean CLI values, a significant increase in the probability of LBP for values above 1.5 was found. Conclusion: A risk of LBP associated with CLI values > 1.5 existed in this worker population. The relevance for other populations requires further study.

• Atmosphere
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• v.28 no.3
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• pp.337-355
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• 2018

Ultrafine particles (< 100 nm in diameter, UFP) are known to be more toxic per unit mass than larger particles and contribute to more than 90% in particle number concentrations in urbanized cities but much less in mass. The major sources of UFP are vehicle emissions in urban areas. Due to their tiny size (the sizes of UFP from vehicle emissions range from 10 to 60 nm depending on engine and fuel types), inhaled UFP can reach the deepest area of respiratory track (e.g., pulmonary alveoli) as well as all of the body via lymph and blood circulation causing various adverse health effects. This article reviews the sources and emission factors of UFP, temporal and spatial distributions in urban areas and their health effects reported by toxicological and epidemiological studies. We also compared the levels of UFP concentrations measured in other countries with those in Korean cities to evaluate the public exposure to UFP in Korea. Ultimately, we expect this study can contribute to developing the risk assessment techniques for public exposure to UFP in the urbanized cities in Korea.

• Clinical and Experimental Reproductive Medicine
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• v.20 no.1
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• pp.65-70
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• 1993

To maintain a good sperm motility is one of the key factors for the successful artificial insemination in retrograde ejaculation, and the sperm motility has been shown to be affected by various environmental factors, including change in pH and osmolarity. Herein we have analyzed the effect of change in pH and osmolarity in urine and normal saline on sperm motility by Sperm Quality Analyzer and Makler counting chamber. Semen, which sampled by masturbation from a 28 year old male and showed normal finding on semen analysis, was used for this study. The results were as follows: 1. When osmolarity was fixed to 300mOsm, pH did not show a definite effect on the sperm moility. However, the motility was generally a bit better in alkaline urine and saline than in acid, particularly than in pH 5.0. 2. When pH was fixed to 7.5, sperm motility was best in urine and saline of 300mOsm. Hyperosmolarity had more adverse.effect on the motility than hypoosmolarity. 3. The sperm motility was worse in the urine than in saline under the same pH and osmolarity. In conclusion, osmolarity has a definite effect on sperm motility, where as pH has relatively little effect. And certain components of urine other than pH and osmolarity might affect the sperm motility.

• Quality Improvement in Health Care
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• v.9 no.2
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• pp.164-175
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• 2002

Background : The purpose of this study was to investigate the current status of medication compliance of outpatients and to analyze the factors contributing to medication non-compliance Methods : Telephone survey was conducted to the 1,000 outpatients who visited medical institutions during the period from January 2002 to April 2002. Subjects were randomly selected from the telephone directories of the nation, and the socio-demographic characteristics of the respondents such as age, gender and region were matched based on those of outpatients in 2001. Results : The results of survey revealed that those who complied with doctors' regimen in the right way accounted for 82.4%. The compliance increased with the strong belief in the medication, less unwanted side effects and inconvenience, more severity of disease, and lower perceived health status. Compliance rate was also higher in the patients group who experienced the drug education by the pharmacists than those who did not. Conclusion : In order to improve drug compliance, drug information on efficacy, adverse reaction, drug interactions, and basic disease information are to be provided to the patients. Drug education needs to be focused not only on providing knowledge of drugs and diseases but also changing attitude on drug use of the patients.

• Journal of Korea Game Society
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• v.16 no.4
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• pp.105-114
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• 2016

This study analyzed a total of 1,025 quests in the 'Warlords of Draenor' which is the fifth expansion set to the massively multiplayer online role-playing game (MMORPG) World of Warcraft, by dividing them into violent and nonviolent quests. There was a total of 515 nonviolent quests which can be categorized into 46 types and a total of 510 violent quests that can be categorized into 7 types. The balance between violent and nonviolent quests shows that the game makers limited the number of adverse factors that can cause the players to be excessively absorbed in the game while successfully incorporating factors that can have positive effect on game players.