• Title/Summary/Keyword: Advanced imaging techniques

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Usefulness of shear wave elastography in the diagnosis of oral and maxillofacial diseases

  • Ogura, Ichiro;Nakahara, Ken;Sasaki, Yoshihiko;Sue, Mikiko;Oda, Takaaki
    • Imaging Science in Dentistry
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    • v.48 no.3
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    • pp.161-165
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    • 2018
  • Purpose: To evaluate the usefulness of shear wave elastography in the diagnosis of oral and maxillofacial diseases. Materials and Methods: Ten patients with oral and maxillofacial diseases and 28 volunteers drawn from our student doctors were examined by shear wave elastography with a 14-MHz linear transducer using an Aplio 300 apparatus (Canon Medical Systems, Otawara, Japan). A statistical analysis of the shear elastic modulus(kPa) of healthy tissue (the sublingual gland, submandibular gland, anterior belly of the digastric muscle, and geniohyoid muscle) in the 28 volunteers was performed using 1-way repeated measures analysis of variance with the Tukey honest significant difference test. The maximum shear elastic modulus(kPa) of 8 patients with squamous cell carcinoma (SCC) and 2 patients with benign lesions was evaluated with the Mann-Whitney U test. The analysis used a 5% significance level. Results: The mean shear elastic modulus of the sublingual gland ($9.4{\pm}3.7kPa$) was lower than that of the geniohyoid muscle ($19.2{\pm}9.2kPa$, P=.000) and the anterior belly of the digastric muscle ($15.3{\pm}6.1kPa$, P=.004). The maximum shear elastic modulus of the SCCs($109.6{\pm}14.4kPa$) was higher than that of the benign lesions($46.4{\pm}26.8kPa$, P=.044). Conclusion: Our results demonstrated the usefulness of shear wave elastography in the diagnosis of oral and maxillofacial diseases. Shear wave elastography has the potential to be an effective technique for the objective and quantitative diagnosis of oral and maxillofacial diseases.

Dose and Image Evaluations of Imaging for Radiotherapy (방사선치료를 위한 영상장비의 선량 및 영상 평가)

  • Lee, Hyounggun;Yoon, Changyeon;Kim, Tae Jun;Kim, Dongwook;Chung, Weon Kyu;Park, Sung Ho;Lee, Wonho
    • Progress in Medical Physics
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    • v.23 no.4
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    • pp.292-302
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    • 2012
  • The patient dose in advanced radiotherapy techniques is an important issue. These methods should be evaluated to reduce the dose in diagnostic imaging for radiotherapy. Especially, the Computed Tomography in radiotherapy has been used widely; hence the CT was evaluated for dose and image in this study. The evaluations for dose and image were done in equal condition due to compare the dose and image simultaneously. Furthermore, the possibility of dose and image evaluations by using the Monte Carlo simulation MCNPX was confirmed. We made the iterative reconstruction for low dose CT image to elevate image quality with Maximum Likelihood Expectation Maximization; MLEM. The system we developed is expected to be used not only to reduce the patient dose in radiotherapy, also to evaluate the overall factors of image modalities in industrial research.

A Study on Invisibility Improvement of Watermarking Image (워터마킹 영상의 비가시성 개선에 관한 연구)

  • Kim, Hyeong-Gyun;Lee, Yang-Weon
    • Journal of Advanced Navigation Technology
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    • v.11 no.3
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    • pp.329-336
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    • 2007
  • The use of digital imaging technique and digital contents based on internet has grown rapidly for last several years, and the needs of digital image protection become more important. For the purpose of copyright protection on digital image, the verification of authentication techniques like content authentication, ownership authentication, illegal copy and etc are needed. Digital watermarking, the invisible encryption technique to insert digital watermark into image, the sophisticated perceptual information should be used for providing transparency and robustness of images on watermarking process. In this paper, we implement the digital watermarking algorithm for preventing forged attack, ownership protection and authentication by transforming the wavelet algorithms in frequency domain in terms of human visual system.

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Brain Metastases from Solid Tumors: an Institutional Study from South India

  • Ghosh, Saptarshi;Rao, Pamidimukkala Brahmananda
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.13
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    • pp.5401-5406
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    • 2015
  • Background: Brain metastases are the most common intra-cranial neoplasms. The incidence is on a rise due to advanced imaging techniques. Aims: The objective of the study was to analyse the clinical and demographic profile of patients with brain metastases from primary solid tumors. Materials and Methods: This is a retrospective single institutional study covering 130 consecutive patients with brain metastases from January 2007 to August 2014. Results: Some 64.6% of the patients were females. The majority were in the sixth decade of life. The site of the primary tumor was the lungs in 50.8% of the cases. The overall median time from the diagnosis of the primary malignancy to detection of brain metastases was 21.4 months. Survival was found to be significantly improved in patients with solitary brain lesions when compared to patients with multiple brain metastases, and in patients undergoing surgical excision with or without cranial irradiation when compared to whole brain irradiation alone. The majority of the cases belonged to the recursive partitioning analysis class II group. Whole brain radiation therapy was delivered to 79% of the patients. Conclusions: Most of the patients with brain metastases in the study belonged to recursive partitioning analysis classes II or III, and hence had poor prognosis. Most of the patients in the Indian context either do not satisfy the indications for surgical excision or are incapable of bearing the high cost associated with stereotactic radiosurgery. Treatment should be tailored on an individual basis to all these patients.

Microstructural changes during semi-solid state processing of hypereutectic Al-Si alloys (고액공존 과공정 Al-Si합금의 교반응고시 미세조직변화)

  • Ryoo, Young-Ho;Kim, Do-Hyang
    • Journal of Korea Foundry Society
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    • v.15 no.5
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    • pp.483-493
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    • 1995
  • The microstructural changes during semi-solid state processing of hypereutectic Al-Si alloy has been investigated in the present study. Stirring of semi-solid slurry results in the morphological changes of the primary Si particles, i.e. from angular rod shape to near-spherical shape. Besides the spherodization of primary Si particles, the average particle size increases, especially, at much higher rate in the final stage than that in the early stage of stirring. Various microstructure characterization techniques, such as anisotropic etching, SEM imaging and ECP analysis, reveal that the spherodization of primary Si particles occurs by the combinations of the mechanisms of coalescence, fracture, and wear of the individual particles. Isothermal shearing of hypereutectic Al-Si at $580^{\circ}C$ shows that spherical ${\alpha}-Al$ particles are formed by the dissociation of Al-Si eutectic structure at the early stage of isothermal shearing. The spherical ${\alpha}-Al$ particles gradually grow by the mechanisms of Ostwald ripening and coalescence of the particles.

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High Intensity Focused Ultrasound for Cancer Treatment: Current Agenda and the Latest Technology Trends (HIFU: 현황 및 기술적 동향)

  • Seo, Jong-Bum
    • The Journal of the Acoustical Society of Korea
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    • v.29 no.2E
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    • pp.55-63
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    • 2010
  • High Intensity Focused Ultrasound (HIFU) is a noninvasive surgical method mainly targeting deeply located cancer tissue. Ultrasound is generated from an extemally located transducer and the beam is focused at the target volume, so that selective damage can be achieved without harm to overlying or surrounding tissues. The mechanism for cell killing can be combination of thermal and cavitational damage. Although cavitation can be an effective means of tissue destruction, the possibility of massive hemorrhage and the unpredictable nature of cavitational events prevent clinical application of cavitation. Hence, thermal damage has been a main focus related to HIFU research. 2D phased array transducer systems allow electronic scanning of focus, multi-foci, and anti-focus with multi-foci, so that HIFU becomes more applicable in clinical use. Currently, lack of noninvasive monitoring means of HIFU is the main factor to limit clinical applications, but development in MRI and Ultrasound Imaging techniques may be able to provide solutions to overcome this problem. With the development of advanced focusing algorithm and monitoring means, complete noninvasive surgery is expected to be implemented in the near future.

Application of Autofluorescence for Confocal Microscopy to Aid in Archaeoparasitological Analyses

  • Morrow, Johnica Jo;Elowsky, Christian
    • Parasites, Hosts and Diseases
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    • v.57 no.6
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    • pp.581-585
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    • 2019
  • Confocal laser scanning microscopy (CLSM) was used to examine archaeoparasitological specimens from coprolites associated with La Cueva de los Muertos Chiquitos (CMC) located near present-day Durango, Mexico. The eggs for 4 different types of parasites recovered from CMC coprolites were imaged using CLSM to assist with identification efforts. While some of the parasite eggs recovered from CMC coprolites were readily identified using standard light microscopy (LM), CLSM provided useful data for more challenging identifications by highlighting subtle morphological features and enhancing visualization of parasite egg anatomy. While other advanced microscopy techniques, such as scanning electron microscopy (SEM), may also detect cryptic identifying characters, CLSM is less destructive to the specimens. Utilizing CLSM allows for subsequent examinations, such as molecular analyses, that cannot be performed following SEM sample preparation and imaging. Furthermore, CLSM detects intrinsic autofluorescence molecules, making improved identification independent of resource and time-intensive protocols. These aspects of CLSM make it an excellent method for assisting in taxonomic identification and for acquiring more detailed images of archaeoparasitological specimens.

A Study on the Material Decomposition of Dual-Energy Iodine Image by Using the Multilayer X-ray Detector (다층구조 엑스선 검출기를 이용한 이중에너지 조영제 영상의 물질 구분에 관한 연구)

  • Kim, Jun-Woo
    • Journal of radiological science and technology
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    • v.44 no.5
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    • pp.465-471
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    • 2021
  • Dual-energy X-ray imaging (DEI) techniques can provide X-ray images that a certain material is suppressed or emphasized by combining two X-ray images obtained from two different x-ray spectrum. In this paper, a single-shot DEI, which uses stacked two detectors (i.e., multilayer detector), is proposed to reduce the patient dose and increase throughput in angiography. The polymethyl methacrylate (PMMA) and aluminum (Al) were selected as two basis materials for material decomposition, and material-specific images are reconstructed as a vector combination of these two materials. We investigate the contrast and noise performance of material-decomposed images using iodine phantoms with various concentrations and diameters. The single-shot DEI shows comparable performances to the conventional dual-shot DEI. In particular, the single-shot DEI shows edge enhancement in material-decomposed images due to the different spatial-resolution characteristics of upper and lower detectors. This study could be useful for designing the multilayer detector including scintillators and energy-separation filter for angiography purposes.

Stochastic nature of magnetic processes studied by full-field soft X-ray microscopy

  • Im, Mi-Young
    • Current Applied Physics
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    • v.18 no.11
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    • pp.1174-1181
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    • 2018
  • In nanomagnetism, one of the crucial scientific questions is whether magnetic behaviors are deterministic or stochastic on a nanoscale. Apart from the exciting physical issue, this question is also of paramount highest relevance for using magnetic materials in a wealth of technological applications such as magnetic storage and sensor devices. In the past, the research on the stochasticity of a magnetic process has been mainly done by macroscopic measurements, which only offer ensemble-averaged information. To give more accurate answer for the question and to fully understand related underlying physics, the direct observation of statistical behaviors in magnetic structures and magnetic phenomena utilizing advanced characterization techniques is highly required. One of the ideal tools for such study is a full-field soft X-ray microscope since it enables imaging of magnetic structures on the large field of view within a few seconds. Here we review the stochastic behaviors of various magnetic processes including magnetization reversal process in thin films, magnetic domain wall motions in nanowires, and magnetic vortex formations in nanodisks studied by full-field soft X-ray microscopy. The origin triggering the stochastic nature witnessed in each magnetic process and the way to control the intrinsic nature are also discussed.

Development of a Lightweight Prediction Model of Fuel Injection Rates from High Pressure Fuel Injectors (고압 인젝터의 분사율 예측을 위한 경량 모델 개발)

  • Lee, Sanggwon;Bae, Gyuhan;Atac, Omer Faruk;Moon, Seoksu;Kang, Jinsuk
    • Journal of ILASS-Korea
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    • v.25 no.4
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    • pp.188-195
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    • 2020
  • To meet stringent emission regulations of automotive engines, fuel injection control techniques have advanced based on reliable and fast computing prediction models. This study aims to develop a reliable lightweight prediction model of fuel injection rates using a small number of input parameters and based on simple fluid dynamic theories. The prediction model uses the geometry of the injector nozzle, needle motion data, injection conditions and the fuel properties. A commercial diesel injector and US No. 2 diesel were used as the test injector and fuel, respectively. The needle motion data were measured using X-ray phase-contrast imaging technique under various fuel injection pressures and injection pulse durations. The actual injector rate profiles were measured using an injection rate meter for the validation of the model prediction results. In the case of long injection durations with the steady-state operation, the model prediction results showed over 99 % consistency with the measurement results. However, in the case of short injection cases with the transient operation, the prediction model overestimated the injection rate that needs to be further improved.