• The Journal of KAIRB
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• v.6 no.1
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• pp.1-4
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• 2024

The strengthening of Institutional Review Board (IRB) and Human Research Protection Program (HRPP) for clinical research on advanced regenerative medicine reflecting the 3 Principles of the Belmont Report (Respect, Beneficence, Justice) is very important. The research institution IRB should naturally be in charge of managing the clinical research process. And it is crucial to reinforce HRPP for the protection of research subjects in institutions conducting advanced regeneration clinical research. So, it is needed to establish a Protection System for Advanced Regenerative Medical Research Subjects composed of clinical research management communication system for advanced regenerative medicine between KAIRB (Korean Association of IRB) of research institutes and National Management Agency for Advanced Regenerative Medical Research. In advanced regenerative medicine clinical research to verify safety and efficacy of the investigational drugs to the subjects with rare and incurable diseases rather than to treat the patients, it is hoped that a management system that guarantees the scientific characteristics of research and the rights of research subjects would be well organized and operated.

• Proceedings of the Korean Nuclear Society Conference
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• 1999.10a
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• pp.140.2-140
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• 1999

• Journal of Auto-vehicle Safety Association
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• v.5 no.1
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• pp.56-61
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• 2013

This paper presents a development of the Advanced Emergency Braking (AEB) Algorithm for passenger vehicles. The AEB is the system to slow the vehicle and mitigate the severity of an impact when a rear end collision probability is increased. To mitigate a rear end collision, the AEB comprises of a millimeter wave radar sensor, CCD camera and vehicle parameters of which are processed to judge the likelihood of a collision occurring. The main controller of the AEB algorithm is composed of the two control stage: upper and lower level controller. By using the collected obstacle information, the upper level controller of the main controller decides the control mode based not only on parametric division, but also on physical collision capability. The lower level controller determines warning level and braking level to maintain the longitudinal safety. To decide the braking level, Last Ponit To Brake and Steer (LPTB/LPTS) are compared with current driving statues. To demonstrate the control performance of the proposed AEBS algorithm's, closed-loop simulation of the AEBS was conducted by using the Matlab simlink and CarSim software.

• Journal of the Korean Society for Aviation and Aeronautics
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• v.29 no.2
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• pp.36-46
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• 2021

The purpose of this study is to ensure safety by proactively identifying hazards that could be derived from changes in mission form and environment as the advanced aircraft such as F-35A stealth fighter, KC-330 Multi-role transport and tanker, RQ-4B high altitude unmanned reconnaissance aircraft, etc are introduced that the Republic of Korea Air Force(ROKAF) has never been operated so far. To this end, the safety management methods based on proactive and predictive approaches used in advanced countries(US Air Force, UK Royal Air Force, Royal Australian Air Force) operating aircraft types same or similar things being newly powered by the ROKAF were reviewed. In addition, the direction for improvement of the safety management methods operating in the ROKAF and the measures necessary for establishment of the new safety management techniques to be applied were suggested.

• Proceedings of the Korean Nuclear Society Conference
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• 2001.05a
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• pp.102.1-102
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• 2001

• Proceedings of the Korean Radioactive Waste Society Conference
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• 2018.11a
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• pp.371-372
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• 2018

• Journal of Sensor Science and Technology
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• v.25 no.5
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• pp.354-364
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• 2016

Recently there have been extensive research activities on the development of on-the-spot detection technologies for bacteria from foods due to growing high demand for food safety. In particular, on-the-spot detection devices using biosensors with rapid, highly sensitive and multiplexed sensing capability are promising for portable or mobile applications. Firstly, issues related to on-the-spot bacteria detection are discussed. Then, detection methods for bacteria, types of biosensors depending on transducing principle and receptors, and platforms for integration of biosensors and signal readers are reviewed. Finally, prospects for development of on-the-spot detection devices are summarized.

• Journal of Food Hygiene and Safety
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• v.37 no.2
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• pp.46-54
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• 2022

Known for its effectiveness in weight loss and diabetes prevention, Gymnema sylvestre products can be found in the US, Japanese, and Indian markets. However, the recommended dosage or safety of these products has not yet been proven. Therefore, development of an analytical method for detecting the content of Gymnema sylvestre in food products is required. Accordingly, this study proposes an analysis method that can examine Gymnema sylvestre in food using LC-ESI-MS/MS and KASP (Kompetitive Allele-Specific PCR) markers. In LC-ESI-MS/MS, a simultaneous analysis method for gymnemic acid and deacylgymnemic acid was optimized using negative ionization mode, and its validation test was completed for solid and liquid samples. In addition, KASP markers were prepared by finding the specific SNP of G. sylvestre in ITS2 and matK through DNA barcodes. The two KASP markers returned positive FAM fluorescence result when combined with G. sylvestre, and this aspect was confirmed in raw G. sylvestre as well. The applicability of the method was tested on 21 different food and healthy functional products containing G. sylvestre purchased on the internet. As a result, although there was a difference in the ratios of gymnemic acid and deacylgymnemic acid in LC-ESI-MS/MS, the index component was detected in all 21 products samples. In the KASP analysis, 9 products returned positive FAM result, and the rest of the products were found to be containing G. sylvestre extract. This study is the first study to use the dual system of LC-ESI-MS/MS and KASP for the analysis of G. sylvestre. The study has confirmed that these two methods are applicable to the examine G. sylvestre content in food products.

• Nuclear Engineering and Technology
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• v.19 no.1
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• pp.42-50
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• 1987

Through a project "Development of Nuclear Safety Parameter Monitoring System", a nuclear data link system was established between Kori nuclear unit 2 and Nuclear Safety Center. We present in this paper the selected parameter sets, a description of the developed pseudo-network software and the functional descriptions of the equipments involved. We also include the conceptual design of the Kori four unit ERF/SPDS system, along with the localization direction for the related software and hardware. hardware.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.8
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• pp.3159-3162
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• 2015

Purpose: This systematic analysis was conducted to evaluate the efficacy and safety of nedaplatin based salvage chemotherapy for treatment of patients with advanced cervical cancer. Methods: Clinical studies evaluating the efficacy and safety of nedaplatin based regimens on response and safety for patients with cervical cancer were identified using a predefined search strategy. Pooled response rates (RRs) were calculated. Results: For nedaplatin based regimens, 5 clinical studies including 264 patients with advanced cervical cancer were considered eligible for inclusion. The analysis showed that, in all patients, pooled RR was 74.6% (197/264). Major adverse effects were leukopenia, thrombocytopenia and nausea/vomiting. No treatment related death occurred with nedaplatin based treatment. Conclusion: This systematic analysis suggests that nedaplatin based regimens are associated with good activity with acceptable tolerability in treating patients with advanced cervical cancer.