• Clinical and Experimental Pediatrics
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• v.62 no.7
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• pp.252-256
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• 2019

The Committee on Infectious Diseases of the Korean Pediatric Society recommended immunization schedule for children and adolescents aged 18 years or younger in the 9th (2018) edition of Immunization guideline. This report provides the revised recommendations made by the committee and summarizes several changes from the 2015 guideline. National immunization program (NIP) launched a human papillomavirus (HPV) immunization for girls aged 12 years in 2016. NIP has also expanded age indication for inactivated influenza vaccine (IIV) to 12 years of age in the 2018-2019 season. Quadrivalent IIVs with a full dose (0.5 mL) are approved for all children of 6 months or older. Recommendations of live attenuated influenza vaccine were removed. For inactivated Japanese encephalitis vaccine, first 2 doses are considered as the primary series. Recommendations for use of newly introduced vaccines (diphtheria-tetanus-acellular pertussis/inactivated poliovirus/Haemophilus influenzae type b, 9-valent HPV, new varicella vaccine, new quadrivalent IIV, and attenuated oral typhoid vaccine) were added. Lastly, monitoring system for adverse events following immunization was updated. Other changes can be found in the 9th edition of Immunization guideline in detail.

• Journal of The Korean Society of Integrative Medicine
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• v.7 no.3
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• pp.149-157
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• 2019

Purpose : This study aims to check the relationship between the size of curvature in scoliosis patients and the reduction rate of curvature after wearing a brace and the relationships of the size of curvature and correction angle with Body Mass Index (BMI). Methods : With 30 adolescent girls who had never worn a brace, their Cobb angle and BMI were measured before manufacturing braces, and their corrected Cobb angle was measured after wearing the manufactured scoliosis braces. Results : The size of the major curvature before wearing the brace and the reduction rate of the curvature after putting it on had a negative correlation in both the major curvature (r=-.465, p<.01) and the minor curvature (r=-.516, p<.01). The size of the minor curvature and the reduction rate of the minor curvature before and after putting it on also had a negative correlation (r=-.429, p<.05). As for the relationship between the size of curvature and BMI, they had a negative correlation in both the major curvature (r=-.141) and the minor curvature (r=-.123), and as for the relationship between the reduction rate of curvature and BMI after wearing the brace, they had a positive correlation in both the major curvature (r=.251) and the minor curvature (r=.136); however, it was not statistically significant (p>.05). Conclusion : In conclusion, the larger the size of curvature, the lower the reduction rate of curvature after wearing the brace became. The larger the size of curvature, the lower the BMI became. The higher the BMI, the higher the correction ratio of the brace became. Therefore, it is judged that it is necessary to provide early treatment and manage body composition before scoliosis progresses.

• Journal of Korean Academy of Nursing
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• v.51 no.1
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• pp.40-53
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• 2021

Purpose: The purpose of this study was to develop and compare the prediction model for suicide attempts by Korean adolescents using logistic regression and decision tree analysis. Methods: This study utilized secondary data drawn from the 2019 Youth Health Risk Behavior web-based survey. A total of 20 items were selected as the explanatory variables (5 of sociodemographic characteristics, 10 of health-related behaviors, and 5 of psychosocial characteristics). For data analysis, descriptive statistics and logistic regression with complex samples and decision tree analysis were performed using IBM SPSS ver. 25.0 and Stata ver. 16.0. Results: A total of 1,731 participants (3.0%) out of 57,303 responded that they had attempted suicide. The most significant predictors of suicide attempts as determined using the logistic regression model were experience of sadness and hopelessness, substance abuse, and violent victimization. Girls who have experience of sadness and hopelessness, and experience of substance abuse have been identified as the most vulnerable group in suicide attempts in the decision tree model. Conclusion: Experiences of sadness and hopelessness, experiences of substance abuse, and experiences of violent victimization are the common major predictors of suicide attempts in both logistic regression and decision tree models, and the predict rates of both models were similar. We suggest to provide programs considering combination of high-risk predictors for adolescents to prevent suicide attempt.

• Journal of The Korean Society of Integrative Medicine
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• v.9 no.1
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• pp.59-67
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• 2021

Purpose : This study examined the factors related to sexual intercourse among adolescents in South Korea. Methods : The study sample was comprised of 65,528 middle and high school students aged 12 to 18 years in 2016. For this study, using the data from the 12th Korea youth risk behavior web-based survey, a chi-squared test, and hierarchical logistic regression analysis we reconducted with the SPSS 22.0 program considering personal, family, school, and regional characteristics. Results : The proportion of adolescents who had sexual intercourse was 6.0 % of boys and 2.7 % of girls, and 6.3 % of high school students and 2.4 % of middle school students. The statistically significant related factors of sexual intercourse were gender, grade, attempted suicide, ever drinking, ever smoking, habitual or purposeful drug use, weekly allowance, and coed school in the final model 4. Adolescents with suicide attempts had 2.49 times more sexual intercourse than adolescents with no experience of suicide attempts. Compared to adolescents without alcohol, smoking, and habitual drug use, those who have experienced alcohol, smoking, habitual or purposeful drug use were 2.22 times, 3.76 times, and 3.39 times more likely to have had sexual intercourse, respectively. Adolescents with a weekly allowance of more than 100,000 won per week and adolescents in coed schools were 2.84 times and 1.40 times more likely to have had sexual intercourse, respectively. Conclusion : Multi-level interventions should be considered in school sexual education programs while considering the substantiality of sex education and the actual adolescents' needs. In addition, sexual health interventions in cyberspace for high-risk groups may be needed to consider the emotional and mental characteristics, given the factors related to sexual intercourse in adolescents.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.25 no.6
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• pp.461-472
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• 2022

Purpose: Golimumab (GLM) is an anti-tumor necrosis factor (TNF)-α antibody preparation known to be less immunogenic than infliximab (IFX) or adalimumab. Few reports on GLM in pediatric patients with ulcerative colitis (UC) are available. This study aimed to review the long-term durability and safety of GLM in a pediatric center. Methods: The medical records of 17 pediatric patients (eight boys and nine girls) who received GLM at the National Center for Child Health and Development were retrospectively reviewed. Results: The median age at GLM initiation was 13.9 (interquartile range 12.0-16.3) years. Fourteen patients had pancolitis, and 11 had severe disease (pediatric ulcerative colitis activity index ≥65). Ten patients were biologic-naive, and 50% achieved corticosteroid-free remission at week 54. Two patients discontinued prior anti-TNF-α agents because of adverse events during remission. Both showed responses to GLM without unfavorable events through week 54. However, the efficacy of GLM in patients who showed primary nonresponse or loss of response to IFX was limited. Four of the five patients showed non-response at week 54. Patients with severe disease had significantly lower corticosteroid-free remission rate at week 54 than those without severe disease. No severe adverse events were observed during the study period. Conclusion: GLM appears to be safe and useful for pediatric patients with UC. Patients with mild to moderate disease who responded to but had some adverse events with prior biologics may be good candidates for GLM. Its safety and low immunogenicity profile serve as favorable options for selected children with UC.

• Journal of dental hygiene science
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• v.22 no.3
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• pp.171-179
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• 2022

Background: In this study, we investigated the changes and factors that affect daily health behaviors due to COVID-19 among adolescents. We intend to provide basic data so that a systematic and comprehensive health education program that includes physical and oral health can be made. Methods: This study was a secondary data analysis of the from the 2019 and 2020 Korea Youth Risk Behavior Web-based Survey. A final sample of 112,251 participants was anlayzed using chi-square test, and ordinal logistic regression. Results: In the case of tooth brushing, the frequency of 'never' increased in most general characteristics compared to before COVID-19. In the case of handwashing, it was found that handwashing behavior increased (increased) after COVID-19 compared to before COVID-19. As a result of confirming the factors affecting tooth brushing behavior before and after COVID-19, it was found that girls brushed teeth 2.2 times more regularly after lunch than boys. As a result of adjusting all other factors, regular tooth brushing behavior after COVID-19 was reduced by 0.79 times compared to before COVID-19. Conclusion: It is judged that it is necessary to operate a comprehensive health management program in the school so that the most basic tooth brushing for oral health and handwashing for health can become a habit. In addition, by confirming the impact of the COVID-19 pandemic on handwashing and tooth brushing behavior through this study, it is expected to be used in the development of policy data such as raising awareness of brushing and improving behaviors applicable in the current and upcoming new pandemic situations.

• The Journal of the Convergence on Culture Technology
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• v.8 no.3
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• pp.149-158
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• 2022

This study was conducted to understand the effects of openness, positive acceptance, physical symptoms, reaction, and emotional sensitivity among adolescents' attitudes toward menstruation, and academic stress on premenstrual syndrome and dysmenorrhea. A questionnaire of 126 high school girls who agreed to participate in the study was analyzed. As a result, the subject's premenstrual syndrome score was 22.48 points and dysmenorrhea was 4.66 points, and it was found that the higher the amount of menstruation, the higher the score of premenstrual syndrome and dysmenorrhea. Factors affecting premenstrual syndrome were openness, physical symptoms, reaction, and emotional sensitivity, and the explanatory power of these variables was 49.9%. In addition, positive acceptance and physical symptoms had a significant effect on dysmenorrhea in adolescents, and explanatory power was 66.3%.

• Korean Journal of Psychosomatic Medicine
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• v.18 no.2
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• pp.62-71
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• 2010

Objectives : The aim of the study was to investigate the prevalence by gender and to evaluate associations of depression, anxiety and sleep disturbances in a large sample of adolescents from the general population. Methods : 1422 subjects, aged 14 years students were recruited in the seven middle-school of the local community. The self-report questionnaire(Children's Depression Inventory : CDI, Beck Anxiety Inventory : BAI and Pittsburgh Sleep Quality Index : PSQI) was used for screening depression, anxiety and sleep disturbances in adolescent. CDI, BAI, and PSQI score was categorized into the following quartiles : $\leq$21, 22-25, 26-28, and $\geq$29 ; $\leq$21, 22-26, 27-31, and $\geq$32 ; $\geq$5, <5. The cut-off score is that CDI is 22, BAI is 22 and PSQI is 5. The result was analyzed using the independent t-test, the chi-square test and logistic regression analyses. Results : The mean CDI score($12.52{\pm}8.32$ vs. $10.39{\pm}7.52$ ; p=0.003), BAI($7.77{\pm}7.93$ vs. $9.84{\pm}9.04$ ; p<0.001) and PSQI($4.57{\pm}2.67$ vs. $3.64{\pm}2.30$ ; p=0.013) of girls were significantly higher than for boys. But, boys in the fourth quartile of CDI(CDI$\geq$29) and BAI(BAI$\geq$32) were at significantly elevated risk for sleep disturbances more than for girls after adjustment for sex, history of psychiatric treatment(CDI odd ratio, 14.66 ; 95% CI, 4.17-51.53, BAI odd ratio, 32.99 ; 95% CI, 4.26-255.39). Conclusion : The results suggest that high CDI, BAI score appears to increase the risk for developing sleep disturbances in boys more than girls.

• Journal of Nutrition and Health
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• v.56 no.6
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• pp.667-682
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• 2023

Purpose: This study aimed to investigate the changes in health behavior, mental health, and nutritional status of Korean adolescents before and after the coronavirus disease 2019 (COVID-19) pandemic outbreak. Methods: A total of 800 adolescents (12~18 years old) who participated in the 2019-2020 Korea National Health and Nutrition Examination Survey (KNHANES) were included as study subjects and divided into four groups (204 middle school boys, 172 middle school girls, 219 high school boys, and 205 high school girls). The 2019 and 2020 KNHANES data were classified into data collected before and after the COVID-19 outbreak, respectively. Results: After the COVID-19 pandemic outbreak, middle school boys showed an increased tendency toward becoming overweight and obese, with significantly increased levels of diastolic blood pressure and insulin. While there was no major change in the subjective health status among adolescents, the high school boys showed a significantly decreased physical activity after COVID-19 outbreak. Moreover, the proportion of middle school students feeling a little stressed significantly increased after the COVID-19 outbreak. The rate of skipping breakfast significantly increased in middle school girls, but the rate of having lunch with companions significantly increased among all adolescents after the COVID-19 outbreak. However, the intake of milk, vegetables, fruits, seaweeds, and pulses significantly decreased, although the intake of sugars, beverages, and seasonings significantly decreased as well, during this period. These changes may lead to an increased proportion of adolescents with insufficient intake of nutrients, including potassium, vitamin C, and riboflavin. Conclusion: These results highlight the impact of COVID-19 on comprehensive changes in physical and mental health status, lifestyle behavior, and nutritional status in adolescents, suggesting the need for targeted prevention and intervention for physical and mental well-being during the pandemic.

• Journal of Korean Academy of Nursing
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• v.20 no.3
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• pp.414-429
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• 1990

Numerous research reports have substantiated the role of stressful life events in relation to the onset of health changes. The relationship tends to hold across different age groups. Theoretically, adolescence has been considered a developmental crisis period of great stress, impoverished coping skills and high vulnerability to biological, social and psychological demands. The research problem addressed by this study was to examine the relationships between stressful life events and health symptom patterns, and the effect of two variables, coping and social, support, theoretically considered to mediate the relationship between stress and health symptoms in adolescents. The following five hypotheses were tested in this research : 1. Health symptoms are positively related to stressful life events in adolescents, 2. Health symptoms are negatively related to coping in adolescents, 3. Health symptoms are negatively related to social support in adolescents, 4. When coping is controlled, the relationship between health symptoms and stressful life events will decrease, and 5. When social support is controlled, the relationship between health symptoms and stressful life events will increase. The study subjects consisted of 1090 high school students of the metropolitan city of Seoul. The following sampling procedure was used : 1. Of the 169 high schools in nine school administrative districts in the city, a proportional sample of ten schools was selected. 2. One class from each of the freshman and sophomore was randomly selected and all the students who were in the sampled class were used as the study sample. The study was limited to freshman and sophomore adolescents, aged 15 to 18(mean＝16.6). Of the 1090 subjects 688(63%) were boys and 402(37%) were girls. An Adolescent Inventory of Stressful Life Events, a Health Symptom Questionnaire and an Adolescent Coping Inventory were adapted for this study. The Norbeck Social Support questionnaire was utilized to collect the data on perceived social support. Five high school teachers in the areas of school health and counselling reviewed the items of each questionnaire for content validity. A pilot study was undertaken to ascertain reliability. Fifty three high school students responded to the questionnaires and gave their opinions on the items. For stressful life events, health symptoms, coping, and social support, the Cronbach's alpha's on the study were .70, .94, .77, and .76, respectively. Research assistants attended all the sampled classes with the school proctor to explain the purpose and procedures of the study to the students. The questionnaires along with a ballpoint pen were distributed to the students who were asked to complete each item. The research assistants left the ballpoint pen with the students as a gift for their cooperation. An average of 50 minutes was required to complete the questionnaires. Using an SPSS, the first, three hypotheses were tested using Gamma, a measure of association for ordinal variables. Partial gamma was used to test the fourth and fifth hypotheses. Patterns of elaboration described by Babbie were selected to interpret the relationship of the three variable analyses. The significance of gamma was determined by Chisquare at a .05 level of significance. There was a positive relationship between health symptoms and stressful life events(Gamma＝.35, p＝.000). Thus the first hypothesis was supported. Unexpectedly, coping was positively related with health symptoms(Gamma＝.13, p＝.000). That is, the higher the coping levels, the greater number of health problems. The third hypothesis, the higher the level of social support, the fewer the health symptoms, was not accepted in this adolescent study group. When coping was controlled, under the condition of low coping the association between health symptoms and stressful life events increased significantly to a partial gamma of .39, and under the condition of high coping it was .30. According to the elaboration model, when one partial relationship is the same or greater than the original and the other is smaller, the control variable should be considered to be specifying the conditions. When social support was controlled the relationship between stressful life events and health symptoms increased under the condition of low social support, but with high social support, the relationship decreased. Both partial gamma were statistically significant at .05 level(.43 and .26 relatively). It can be interpreted that stressful life events are strongly and positively related to health symptoms under the condition of low social support, however this relationship can not be expected with high social support. Thus, the last two hypotheses were conditionally sustained. In this study, the relationships between stressful life events and health symptoms, and the specified me diating roles of coping and social support were found to have statistical interaction. This finding supports the theoretical position of this study. It suggests that stressful life events would create high susceptability to biological social and psychological health symptoms and coping and social support buffering the relationship between stressful life events and health symptom. The findings of this study have implications for nursing practice. When adolescents are confronted with non-developmental life events that are perceived as stressful, nurses should recognize the evidence of the stress-buffering effect of coping and social support on health symptoms and utilize the diverse sources of social support that are readily available to adolescents.