• Title/Summary/Keyword: Administration department

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Guideline for the Clinical Trials Evaluation for Gastritis (위염치료제의 임상시험평가지침 연구)

  • Song, Yun-Kyoung;Jin, Sun-Kyung;Han, Eui-Sik;Ahn, Mee-Ryung;Jung, Ju-Yeon;Lee, Rhee-Da;Cho, Il-Yong;Kim, Dong-Sub;Ji, Eun-Hee;Park, Hyo-Young;Oh, Jung-Mi;Shin, Won;Lee, Sun-Hee;Kim, In-Kyu
    • YAKHAK HOEJI
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    • v.55 no.4
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    • pp.345-351
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    • 2011

  • Gastritis is the most common disease among Korean. The demand for the development of gastritis drugs has been increasing. Currently, however, there is no guideline available for the clinical evaluation of gastritis drugs worldwide. As a consequence, domestic and international pharmaceutical companies make errors in the drug development processes, and it becomes difficult for them to establish the scientific validity and objectivity of newly developed drugs. The objective of this study was to develop the Guideline for Clinical Trials Evaluation of Gastritis which can be used in improving the quality and consistency of clinical trials. First, we collected and reviewed the clinical trials on gastritis drugs that were available from Japan Pharmaceuticals and Medical Devices Agency and Korea Food and Drug Administration (KFDA), and investigated the recent research trends on clinical trials of gastritis drugs. Reviewers from KFDA and National Institute of Food and Drug Safety Evaluation and scientific experts from the pharmaceutical industries developed the guidelines through regularly scheduled meetings. Opinions and consultation from academic fields and industry experts were also obtained. This project will provide the clinical trial practitioners, investigator and reviewers the scientific and rational guidelines for performance and evaluation of clinical trials for gastritis drugs. Furthermore, we hope this guideline contributes to establishing the national competitiveness, improving the quality of clinical trial, and encouraging researches on drug development for gastritis.

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Analysis of The Application of Information and Innovation Experience in The Training of Public Administration Specialists

  • Smyrnova, Iryna;Akimov, Oleksandr;Krasivskyу, Orest;Shykerynets, Vasyl;Kurovska, Ilona;Hrusheva, Alla;Babych, Andrii
    • International Journal of Computer Science & Network Security
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    • v.21 no.3
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    • pp.120-126
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    • 2021

  • The article analyzes the possibility of using information and innovation experience in training public administration specialists, and also explores the system of training public administration and management specialists abroad. It was determined that in the European Union, Japan and other developed countries, three concepts of qualified personnel training will be developed: the concept of specialized training is focused on the present or near future and is relevant for the respective workplace; the concept of multidisciplinary training is effective from an economic point of view, as it increases intra-production and non-production mobility of an employee; the concept of learner-centered learning with the aim of developing human qualities.

  • https://doi.org/10.22937/IJCSNS.2021.21.3.16 인용 PDF KSCI

A study of "administration time in herbal medicine" (한약의 복용시간에 관한 고찰)

  • Park, Pil-Sang;Kang, Ok-Hwa;Lee, Go-Hoon;Park, Shin-Young;Seong, Man-Jun;Kim, Yeong-Mok;Song, Ho-Joon;Kwon, Dong-Yeul
    • The Korea Journal of Herbology
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    • v.22 no.4
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    • pp.1-8
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    • 2007

  • Objectives : There are many causes that may affect efficacy of a drug but the time of administration for the Herbal Medicine is among the most important factors. Traditionally, administration of medicine was prohibited during the meal time along with food and the time of administration has been highly regarded in medical practitioners. The rules of administration time are stated in a book titled, "Materia Medica" but it lacked the details and index. Thus, the systemized administration rules for Herbal Medicine were prepared. Methods : The rules were drawn from both ancient teachings and the experiences from modern clinics. Ancient teachings about the administration are focused on treatment of a disease by utilizing biorhythm of the body in accordance of changes in Yin and Yang and Day and Night. Results : It means the medicine should be prepared and administered at the appropriate time of the day and this type of administration method is thought to be superior to the western method such as "once a day" or "twice a day in the morning and evening" that does not take consideration of cold, hot, warm and cool properties of the medicine. If the prescription is assigning appropriate medicine, administration time is an important method of maximizing drug efficacy. Conclusion : With the ancient teaching in mind, it was concluded that, the drug administration time must be determined with regard to properties of the drug and the condition of the patient.

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Effects of Croton Tiglii Semen Water Extracts on the Renal Function and Endocrine Function in Rats (파두(巴豆) 추출액(抽出液)의 백서(白鼠) 신장기능(腎臟機能) 및 혈장(血漿) Hormone에 미치는 영향(影響))

  • Kim, Yu-Kam;Yu, Yun-Cho;Ryu, Do-Gon;Yum, Ki-Bok;Lee, Ho-Sub
    • The Journal of Korean Medicine
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    • v.18 no.2
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    • pp.214-222
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    • 1997

  • The aim of this experiments was to investigate the effect of Croton. Tiglii. semen water extract on the renal function, plasma renin activity, plasma levels of atrial natriuretiu peptide and aldosterone in rats. The results of this study were as follows: 1. Water balance was not changed significantly after the administration of Croton Tiglii semen water extract. 2. Urine volume decreased significantly after the administration of Croton Tiglii semen water extract $80{\mu}l/200g$. 3. Urinary excretion of sodium increased significantly after the administration of Croton Tiglii semen water extract $40{\mu}l/200g$, but decreased significantly after the administration of Croton Tiglii semen water extract $80{\mu}l/200g$. 4. Urinary excretion of potassium decreased significantly after the administration of Croton Tiglii semen water extract $80{\mu}l/200g$. 5. Urinary excretion of chloride was not changed significantly after the administration of Croton Tiglii semen water extract. 6. Free water clearance was not changed significantly after the administration of Croton Tiglii semen water extract. 7. Urinary excretion of creatinine increased significantly after the administration of Croton Tiglii semen $40{\mu}l/200g$. 8. Plasma renin activity was not changed significantly after administration of Croton Tiglii semen water extract. 9. Plasma levels of atrial natriuretic peptide increased significantly after administration of Croton Tiglii semen water extract. 10. Plasma levels of aldosterone increased significantly after administration of Croton Tiglii semen $40{\mu}l/200g$.

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