Effects of Croton Tiglii Semen Water Extracts on the Renal Function and Endocrine Function in Rats

파두(巴豆) 추출액(抽出液)의 백서(白鼠) 신장기능(腎臟機能) 및 혈장(血漿) Hormone에 미치는 영향(影響)

  • Kim, Yu-Kam (Department of Physiology, College of Oriental Medicine, WonKwang University) ;
  • Yu, Yun-Cho (Department of Physiology, College of Oriental Medicine, WonKwang University) ;
  • Ryu, Do-Gon (Department of Physiology, College of Oriental Medicine, WonKwang University) ;
  • Yum, Ki-Bok (Department of Physiology, College of Oriental Medicine, WonKwang University) ;
  • Lee, Ho-Sub (Department of Physiology, College of Oriental Medicine, WonKwang University)
  • 김유겸 (원광대학교 한의과대학 생리학교실) ;
  • 유윤조 (원광대학교 한의과대학 생리학교실) ;
  • 류도곤 (원광대학교 한의과대학 생리학교실) ;
  • 염기복 (원광대학교 한의과대학 생리학교실) ;
  • 이호섭 (원광대학교 한의과대학 생리학교실)
  • Published : 1997.10.30

Abstract

The aim of this experiments was to investigate the effect of Croton. Tiglii. semen water extract on the renal function, plasma renin activity, plasma levels of atrial natriuretiu peptide and aldosterone in rats. The results of this study were as follows: 1. Water balance was not changed significantly after the administration of Croton Tiglii semen water extract. 2. Urine volume decreased significantly after the administration of Croton Tiglii semen water extract $80{\mu}l/200g$. 3. Urinary excretion of sodium increased significantly after the administration of Croton Tiglii semen water extract $40{\mu}l/200g$, but decreased significantly after the administration of Croton Tiglii semen water extract $80{\mu}l/200g$. 4. Urinary excretion of potassium decreased significantly after the administration of Croton Tiglii semen water extract $80{\mu}l/200g$. 5. Urinary excretion of chloride was not changed significantly after the administration of Croton Tiglii semen water extract. 6. Free water clearance was not changed significantly after the administration of Croton Tiglii semen water extract. 7. Urinary excretion of creatinine increased significantly after the administration of Croton Tiglii semen $40{\mu}l/200g$. 8. Plasma renin activity was not changed significantly after administration of Croton Tiglii semen water extract. 9. Plasma levels of atrial natriuretic peptide increased significantly after administration of Croton Tiglii semen water extract. 10. Plasma levels of aldosterone increased significantly after administration of Croton Tiglii semen $40{\mu}l/200g$.

Keywords

References

  1. 臟腑辨證論治 金完熙;崔永達
  2. 大韓韓醫學會誌 v.8 no.1 腎機能에 대한 東西醫學的 考察 柳道坤(외)
  3. 神農本草經 v.3
  4. 標準本草學 金晸壽
  5. 申氏本草學(各論) 申佶求
  6. 本草綱目 李時珍
  7. 臨床應用 漢藥炮製學 金在佶(編)
  8. 中草藥 曲京峰;張少華(編)
  9. 抗癌本草 常敏毅(編)
  10. 痞氣丸이 白血病과 淋巴腫患者에서 抽出한 癌細胞에 미치는 抗癌 效果 韓相日
  11. 巴豆를 加味한 四君子湯 및 四物湯의 抗癌效果에 대한 硏究 李永燦
  12. 巴豆加大黃의 抗腫瘍效果와 自然殺害細胞의 活性에 미치는 影響 朴鍾郁
  13. In quantitative Clinical Chemistry Methods v.2 Phillips, R.A.;Peter, J.P.;Vanslyke, D.D.(eds.)
  14. J. Exp. Zool. v.242 Radioim munoassay and characterization of reninangiotensin system in the fresh water turtle. Cho, K.W.;Kim, S.H.;Koh, G.Y.
  15. 약초의 성분과 이용 문관심
  16. 臟腑辨證論治 金完熙;崔達永(編)
  17. 黃帝內經素問校譯 山東中醫學院 河北醫學院校(譯)
  18. 腎臟學 서울대학교 의과대학
  19. 人體의 生理 金祐謙
  20. 十棗湯 煎湯液과 十棗湯加 附子 煎湯液 投與가 白鼠의 腎臟機能에 미치는 影響 金明東
  21. 圓光韓醫學會誌 v.6 no.1 猪苓 및 茯苓 煎湯液이 白鼠의 腎臟機能, renin 活性度, 血漿 atrial natriuretic peptide 및 ldosterone 濃度에 미치는 影響 李昊燮;兪閏朝
  22. 東醫生理學會誌 v.11 no.2 五苓散 煎湯液의 胃內 直接投與가 白鼠이 腎臟機能과 血漿 renin 活性度 및 atrial natriuretic peptide 濃度에 미치는 影響 김경아;민영기;이호섭;류도곤
  23. 東醫生理學會誌 v.10 no.1 猪苓湯 煎湯液이 白鼠이 腎臟機能에 미치는 影響 田永奭;兪閏朝;柳道坤;李昊燮
  24. 東醫生理學會誌 v.8 no.1 逐水湯 煎湯液이 白鼠 腎臟機能에 미치는 影響 鄭玉參;金明東;柳道坤;李昊燮