• 한국병원경영학회지
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• 제24권3호
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• pp.27-37
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• 2019

Purpose: The Purpose of this study is to provide basic data for solving mental health problems of people with disabilities by analyzing the relationship between leisure activities and the mental health. Methods: We used the chi-square test and the logistic regression model to analyze the data of the National Survey of People with Disabilities in 2017. 6,437 responses of secondary processed data were used in the analysis, Socio-economic, health behaviors and risk variables that affect the mental health of people with Disabilities were used as control variables. Result: As a result of the analysis, People with disabilities who are satisfied with their leisure activities have less depression for two weeks and less suicidal impulses (Depression: [OR]=1.80 p-value<.0001, Suicide Impulse: [OR]=2.26 p-value<.0001). In the case of the experience of leisure activities, some significance was relevant to depression for two weeks (Depression: [OR]=1.65 p-value=0.0052). Conclusion: In order to improve mental health of people with disabilities, it is necessary to provide opportunities for participation in leisure activities by improving the socioeconomic status of them. In addition, a high quality leisure program should be provided that meets the individual's needs to increase the satisfaction of leisure activities for people with disabilities.

• 인간식물환경학회지
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• 제24권4호
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• pp.329-339
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• 2021

Background and objective: This study was conducted to obtain empirical data for deriving necessary items for the creation and management of gardens in urban agricultural parks while maintaining the publicness of the place by examining the difference in perception among park visitors about the gardens in the public parks. Methods: A survey was conducted on users of urban agricultural parks in 6 locations and 113 copies of the questionnaire were collected. After understanding the demographic characteristics and the current use of the garden, we identified the importance of the necessary items for the public gardens. Results: 108 subjects(95.6%) responded that gardens are needed in urban parks, for psychological and emotional health (26.2%) and for interaction and friendship with family and neighbors(23.2%). For use of garden crops, most were private sales(96 subjects, 64.4%), and both sales preferred to partially donate their crops. Most used communal gardens operated by public institutions(30.1%). It was found that 96.4% of the respondents were satisfied with gardening activities, and 107(94.7%) of them showed their intention to participate in the gardening in the future. The Kaiser Meyer Olkin value was .848 and the significance level was .001, proving the validity of factor analysis. The factors were named composition elements(Factor 1), management items(Factor 2), convenience elements(Factor 3), and operational facilities(Factor 4). In the survey on the creation and management of gardens in urban agricultural parks, there were no statistically significant differences, but all items had correlations. Conclusion: The results have reflected the needs of actual users in establishing the plans to operate urban gardens, thereby having great utility value as the basic data for continuous garden management. Further research can be conducted to derive detailed elements that can guarantee sustainability of urban gardens and suggest high-quality data for management of gardens in urban agricultural parks.

• 한국병원경영학회지
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• 제28권3호
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• pp.58-67
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• 2023

Purpose: The purpose of this study was to analyze the factors associated with long-term hospitalized patients in long-term care hospitals using the quality assessment data for long-term care hospitals by the Health Insurance Review. Methods: Among 1,376 long-term care hospitals, frequency analysis and descriptive statistics were used to analyze the characteristics of these hospitals. Multiple linear regression was conducted to examine the associations between infrastructure characteristics, medical personnel characteristics, health outcomes and the proportion of long-term hospitalized patients. Results: The research findings indicate that the number of patients per doctor, the number of patients per nurse, and the number of patients per nursing staff were positively associated with the proportion of long-term hospitalized patients. Among health outcomes, a higher proportion of patients with more than a 5% weight loss compared to the previous month and the proportion of patients showing improvement in ADL, were more likely to have a lower proportion of long-term hospitalized patients. However the proportion of diabetic patients with HbA1c test results within the appropriate range was positively associated with the proportion of long-term hospitalized patients. Conclusion: The present study results provide fundamental data for the establishment of policies for long-term care hospitals. Based on this study, it is important to suggest screening methods for unnecessary long-term hospitalizations, such as sufficient medical personnel to improve the quality of care in long-term care hospitals. It is also necessary to clearly separate the roles of medical institutions and long-term care facilities and implement policies to support patients' social reintegration.

• International Journal of Industrial Entomology and Biomaterials
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• 제25권2호
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• pp.209-213
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• 2012

The propolis was collected from the whole part of Korea Peninsula, such as central, southern, and Jeju island, to analyze the general composition including total flavonoid and phenolic contents, heavy metals, colors, amino acids, and crude lipid. The total flavonoid and phenolic contents of middle region in Korea Peninsula (4.26% and 13.06 g/100 g gallic acid) were higher than southern region (2.53%, 10.9 g/100 g gallic acid) and Jeju island (0.03%, 7.22g/100 g gallic acid), respectively. The heavy metals contents showed that Zn contents were found in $0.44{\pm}0.2ppm$ and a harmful heavy metal such as Cr, Cd, Pb, Ni, Cu, As, and Hg were not detected at all in our experiment. The colors of extracted propolis showed a various spectrum from yellow to red purple. Various amino acids were also detected as proline, valine, methionine and the average crude lipid contents of propolis were 42.4%. All data collected in South Korea were very first executed in our institution for the purposes of utilizing and developing the industrial insects, honeybees as well as silkworm.

• 한국화재소방학회논문지
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• 제34권4호
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• pp.125-134
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• 2020

본 연구는 선행연구에서 다뤄지지 않았던 예방소방과 대비소방을 수방수요에 포함시켜 소방예산에 미치는 영향을 실증적으로 분석하고자 수행되었다. 이를 위해 16개 광역자치단체에서 수행된 예방소방행정(건축허가동의, 특정 소방대상물, 다중이용업, 소방특별조사), 대비소방행정(소방교육 및 훈련), 대응소방행정(화재진압출동, 구급출동) 그리고 소방예산에 대한 11년(2008년-2018년)의 패널자료를 이용하여 실증분석을 실시하였다. 분석결과, 예비소방행정의 소방특별조사, 대비소방행정의 소방교육 및 훈련, 그리고 대응소방행정의 화재진압출동은 소방예산에 유의미한 음(-)의 효과가 있는 것으로 나타났다. 한편, 대응소방행정의 구급출동은 0.01%수준에서 소방예산에 유의미한 양(+)의 효과를 미치는 것으로 나타났다. 이는 우리나라 소방행정의 패러다임이 재난수용(복구중심)에서 재난대응(현장대응중심)을 지나 재난대비(대비중심)로 변화되고 있다는 공공정책을 지지하는 연구결과이다.

• 한국환경과학회지
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• 제13권12호
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• pp.1109-1115
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• 2004

This study was investigated the residual contents of sulfur dioxide on the 373 kinds of herbal medicine distributed from Korea, China, and Japan. A modified Monier-Williams method was described for the determination of $SO_{2}$ contents in herbal medicines. The residual contents of $SO_{2}$ were not detected at 221 products$(59.8{\%})$ in total 373 products. Regardless of region, $SO_{2}$ contents were not found at Farfarae Flos, Zizyphi Spinosi Semen, Castanea crenata, and Strychni Ignatii Semen. But it's found at Asparagi Radix, Codonopsitis Radix, Lilii Bulbus, and Kaempferiae Rhizoma of every region collected the samples. Also, $SO_{2}$ contents were not detected at the herbal medicines which collected cultural fields of dometic. $SO_{2}$ contents ranged 11$\~$3990 mg/kg(mean 152 mg/kg) at domestic samples, 11$\~$3440 mg/kg(mean 603 mg/kg) at imported samples. After treated with water wash and hot water extraction, the reduction rates of sulfur dioxide were appeared with $24.4{\%}\~68.7{\%}\;and\;83.8{\%}\~100.0{\%},$ respectively. These data will be used to establish a criteron of residual sulfur dioxide in herbal medicines.

• Journal of Microbiology and Biotechnology
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• 제30권9호
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• pp.1282-1289
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• 2020

Previously, we performed an in silico analysis of the Periplaneta americana transcriptome. Antimicrobial peptide candidates were selected using an in silico antimicrobial peptide prediction method. It was found that periplanetasin-5 had antimicrobial activity against yeast and gram-positive and gram-negative bacteria. In the present study, we demonstrated the anti-inflammatory activities of periplanetasin-5 in mouse macrophage Raw264.7 cells. No cytotoxicity was observed at 60 ㎍/ml periplanetasin-5, and treatment decreased nitric oxide production in Raw264.7 cells exposed to lipopolysaccharide (LPS). In addition, quantitative RT-PCR and enzyme-linked immunosorbent assay revealed that periplanetasin-5 reduced cytokine (tumor necrosis factor-α, interleukin-6) expression levels in the Raw264.7 cells. Periplanetasin-5 controlled inflammation by inhibiting phosphorylation of MAPKs, an inflammatory signaling element, and reducing the degradation of IκB. Through LAL assay, LPS toxicity was found to decrease in a periplanetasin-5 dose-dependent manner. Collectively, these data showed that periplanetasin-5 had anti-inflammatory activities, exemplified in LPS-exposed Raw264.7 cells. Thus, we have provided a potentially useful antibacterial peptide candidate with anti-inflammatory activities.

• 대한한방부인과학회지
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• 제21권3호
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• pp.1-17
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• 2008

Purpose: Scutellaria baicalensis is a herb which has effect of eliminating heat, drying dampness, purging away fire, detoxicating. Clinically, has been used to remove fever and control of inflammation. We have studied in series to investigate the effective traditional oriental medicines of treatment for endometriosis. In this study, the effects of Scutellaria baicalensis administrated orally or rectally on surgically induced endometriosis in rat were investigated. Methods: The endometrial tissues of rats were autografted to their small intestine. Rats with surgically induced endometriosis were administered with Scutellaria baicalensis extracts for 40 days orally or rectally. We observed the tissue size of ectopic uterine implants at the mesenteric with the naked eye and examined the concentration of estradiol, progesterone, $TNF-{\alpha}$ and IL-2, IL-4, IL-6 and IL-10 in serum. Also, we inquired which was more effective between oral administration groups and rectal administration groups. Results: The size of ectopic uterine implants of orally or rectally treated groups was much smaller than those of control groups. The concentrations of estradiol, progesterone, $TNF-{\alpha}$, IL-2 and IL-6 were significantly decreased in oral administration experimental group compared with the control group. The concentrations of progesteron, $TNF-{\alpha}$, IL-2 and IL-6 were significantly decreased in rectal administration experimental group compared with the control group. The efficiency of oral administration group was better than that of rectal administration group at the serum concentration of estradiol and IL-4. Conclusion: Our data suggest that Scutellaria baicalensis inhibit the inflammation induced from ectopic uterine implants at the mesenteric wall and inhibit the growth of ectopic uterine implants. Judging from the above results, it can be suggested that Scutellaria. baicalensis should be a useful agent for inhibiting the inflammation induced from ectopic uterine implants and the proliferation of endometriosis. Maybe, oral administration of Scutellaria baicalensis is more effective than rectal administration.

• Journal of Microbiology and Biotechnology
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• 제29권5호
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• pp.687-695
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• 2019

In a previous work, we performed de novo RNA sequencing of Allomyrina dichotoma using next generation sequencing and identified several antimicrobial peptide candidates based on transcriptome analysis. Among them, a cationic antimicrobial peptide, allomyrinasin, was selected bioinformatically based on its physicochemical properties. Here, we assessed the antimicrobial and anti-inflammatory activities of allomyrinasin against microorganisms and mouse macrophage Raw264.7 cells. Allomyrinasin showed antimicrobial activities against various microbes and decreased the nitric oxide production of the lipopolysaccharide-induced Raw264.7 cells. Furthermore, quantitative RT-PCR and ELISA revealed that allomyrinasin reduced cytokine expression levels in the Raw264.7 cells. We also identified inducible nitric oxide synthase, cyclooxygenase-2 expression, and $PGE_2$ production through western blot analysis and ELISA. We confirmed that allomyrinasin bound to bacterial cell membranes via a specific interaction with lipopolysaccharides. Taken together, these data indicate that allomyrinasin has antimicrobial and anti-inflammatory activities as exemplified in lipopolysaccharide-induced Raw264.7 cells. We have provided a potentially useful antimicrobial peptide candidate that has both antimicrobial and anti-inflammatory activities.

• 한국작물학회지
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• 제64권3호
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• pp.213-224
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• 2019

There is an increasing frequency in the occurrence of abnormal weather phenomena such as sharp increases and decreases in temperature. Under these weather conditions, the heading time of rice changes unexpectedly, which poses problems in agriculture. Therefore, we investigated the effect of temperature on the heading response at different growth stages in rice. During the period from transplanting to heading, the plants were subjected to different temperature treatments, each for a 9-day period, to observe the heading response. For the heading date analysis, "heading date" was defined as the number of days from transplanting to the appearance of the first spikelet. We found that the influence of temperature increased in the order of rooting stage, followed by meiosis, early tillering, spikelet differentiation, and panicle initiation stage in all ecological types and cultivars. In particular, unlike the results reported previously, the effect of temperature on heading during the photo-sensitive period was very small. Meanwhile, the influence of temperature on vegetative growth response at different growth stages was not consistent with heading response. These results can be used as basic data for predicting the variation in heading date owing to temperature variation at each growth stage. In addition, we propose that the concept of day length should be included in determining the influence of temperature on the photo-sensitive period.