• Journal of the Korean Data and Information Science Society
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• v.17 no.3
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• pp.999-1007
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• 2006

The semiparametric gamma frailty models have been often used for multivariate survival analysis because they give an explicit marginal likelihood. The commonly used estimation procedure is the profile likelihood method based on marginal likelihood, which provides the same parameter estimates as the EM algorithm. In this paper we show in finite samples the standard profile-likelihood method can lead to an underestimation of parameters, particularly for the frailty parameter. To overcome this problem, we propose an adjusted profile-likelihood method. For the illustration a numerical example and a small-sample simulation study are presented.

• Asian-Australasian Journal of Animal Sciences
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• v.13 no.8
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• pp.1035-1039
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• 2000

This study developed a Poisson generalized linear mixed model and a procedure to estimate genetic parameters for count traits. The method derived from a frequentist perspective was based on hierarchical likelihood, and the maximum adjusted profile hierarchical likelihood was employed to estimate dispersion parameters of genetic random effects. Current approach is a generalization of Henderson's method to non-normal data, and was applied to simulated data. Underestimation was observed in the genetic variance component estimates for the data simulated with large heritability by using the Poisson generalized linear mixed model and the corresponding maximum adjusted profile hierarchical likelihood. However, the current method fitted the data generated with small heritability better than those generated with large heritability.

• The Korean Journal of Applied Statistics
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• v.13 no.2
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• pp.407-414
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• 2000

Carroll and Ruppert(1988) analyzed the esterase assay data with regression model based on quasi-likelihood. Jung and Lee(1997) introduced a goodness-of-fit test for testing the adequacy of the quasi-likelihood and claimed that there is no gross inadequacy with the model because their test was not rejected. However, Lee and Xelder(199S)'s residual plots revealed that the model did not sufficiently reflect the increase of the variance with that of the mean. In this paper, we re-analyze the esterase assay data with the joint modelling of mean and dispersion in Lee and l\elder(1998) and evaluate the validity of the fitted model by applying the residual plots. And it is illustrated that Lee and Nelder(199S)'s restricted likelihood is more efficient in goodness-of-fit test for the dispersion model.