• Food Science of Animal Resources
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• v.35 no.1
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• pp.91-100
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• 2015

The present study was conducted to screen candidate probiotic strains for anti-inflammatory activity. Initially, a nitric oxide (NO) assay was used to test selected candidate probiotic strains for anti-inflammatory activity in cultures of the murine macrophage cell line, RAW 264.7. Then, the in vitro probiotic properties of the strains, including bile tolerance, acid resistance, and growth in skim milk media, were investigated. We also performed an in vitro hydrophobicity test and an intestinal adhesion assay using Caenorhabditis elegans as a surrogate in vivo model. From our screening, we obtained 4 probiotic candidate lactic acid bacteria (LAB) strains based on their anti-inflammatory activity in lipopolysaccharide (LPS)-stimulated RAW 264.7 cell cultures and the results of the in vitro and in vivo probiotic property assessments. Molecular characterization using 16S rDNA sequencing analysis identified the 4 LAB strains as Lactobacillus plantarum. The selected L. plantarum strains (CAU1054, CAU1055, CAU1064, and CAU1106) were found to possess desirable in vitro and in vivo probiotic properties, and these strains are good candidates for further investigations in animal models and human clinical studies to elucidate the mechanisms underlying their anti-inflammatory activities.

• Progress in Medical Physics
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• v.27 no.4
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• pp.196-202
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• 2016

We aim to develop the breast bolus by using a 3D printer to minimize the air-gap, and compare it to commercial bolus used for patients undergoing reconstruction in breast cancer. The bolus-shaped region of interests (ROIs) were contoured at the surface of the intensity-modulated radiation therapy (IMRT) thorax phantom with 5 mm thickness, after which the digital imaging and communications in mdicine (DICOM)-RT structure file was acquired. The intensity-modulated radiation therapy (Tomo-IMRT) and direct mode (Tomo-Direct) using the Tomotherapy were established. The 13 point doses were measured by optically stimulated luminescence (OSLD) dosimetry. The measurement data was analyzed to quantitatively evaluate the applicability of 3D bolus. The percentage change of mean measured dose between the commercial bolus and 3D-bolus was 2.3% and 0.7% for the Tomo-direct and Tomo-IMRT, respectively. For air-gap, range of the commercial bolus was from 0.8 cm to 1.5 cm at the periphery of the right breast. In contrast, the 3D-bolus have occurred the air-gap (i.e., 0 cm). The 3D-bolus for radiation therapy reduces the air-gap on irregular body surface that believed to help in accurate and precise radiation therapy due to better property of adhesion.

• Journal of Acupuncture Research
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• v.19 no.2
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• pp.149-163
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• 2002

Objective : We have studied literatures of Renying Qi mouth comparison pulse diagnosis theory and distinguished the excess, deficiency and quick-temper of pulse as the measurement parameter of Renying Qi mouth pulse diagnosis. Methods : We have acquired pulse signals of Renying Qi mouth by using diagnostic equipment of Renying Qi mouth pulsation and estimated reappearance of pulse signals. Results : 1. The measurement parameter of Renying Qi mouth pulse diagnosis distinguishes the excess, deficiency and quick-temper of pulse through relative comparison of Renying Qi mouth. 2. When we acquired the pulse singals of Renying Qi mouth by using diagnostic equipment, the property, measuring area, bias pressure, contact or adhesion state of the sensor are considered. 3. As getting the pulse signal of Renying Qi mouth, the sensor of a sound detective mode is effective. 4. The diagnostic equipment of Renying Qi mouth pulse is assessed as being significant reappearance.

• Journal of Conservation Science
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• v.24
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• pp.37-42
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• 2008

Stability of the moving historic sites have something to do with the degree of easiness of work as well as physical property of polymer product. These agents should be able to use without the effect of outer environments like water or low temperature and must have stability during progress of working the peel off Urethane pre-product from Epoxy surface. So, we synthesized low viscosity epoxy resin and hardener with best physical quality and separation media for the moving of historical sites. These products have very good tension strength, adhesion strength, low viscosity and various physical properties that the users want. Particularly, separation media products have good separation of Urethane pre-products surface and Epoxy final product surface.

• International Journal of Highway Engineering
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• v.17 no.3
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• pp.77-83
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• 2015

PURPOSES : In this study, a fracture-based finite element (FE) model is proposed to evaluate the fracture behavior of fiber-reinforced asphalt (FRA) concrete under various interface conditions. METHODS : A fracture-based FE model was developed to simulate a double-edge notched tension (DENT) test. A cohesive zone model (CZM) and linear viscoelastic model were implemented to model the fracture behavior and viscous behavior of the FRA concrete, respectively. Three models were developed to characterize the behavior of interfacial bonding between the fiber reinforcement and surrounding materials. In the first model, the fracture property of the asphalt concrete was modified to study the effect of fiber reinforcement. In the second model, spring elements were used to simulated the fiber reinforcement. In the third method, bar and spring elements, based on a nonlinear bond-slip model, were used to simulate the fiber reinforcement and interfacial bonding conditions. The performance of the FRA in resisting crack development under various interfacial conditions was evaluated. RESULTS : The elastic modulus of the fibers was not sensitive to the behavior of the FRA in the DENT test before crack initiation. After crack development, the fracture resistance of the FRA was found to have enhanced considerably as the elastic modulus of the fibers increased from 450 MPa to 900 MPa. When the adhesion between the fibers and asphalt concrete was sufficiently high, the fiber reinforcement was effective. It means that the interfacial bonding conditions affect the fracture resistance of the FRA significantly. CONCLUSIONS : The bar/spring element models were more effective in representing the local behavior of the fibers and interfacial bonding than the fracture energy approach. The reinforcement effect is more significant after crack initiation, as the fibers can be pulled out sufficiently. Both the elastic modulus of the fiber reinforcement and the interfacial bonding were significant in controlling crack development in the FRA.

• Journal of the Society of Disaster Information
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• v.11 no.2
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• pp.235-243
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• 2015

The methods to improve the protection and explosion-proof performance of concrete structures include the backside reinforcement or concrete material property improvement and the addition of structural members or supports to increase the resistance performance, but they are inefficient in terms of economics and structural characteristics. This study is about the basic study on the fiber composite panel cover, and the nano-composite material and adhesive as the filler, to maximize the specific performance of each layer and the protection and explosion-proof performance as the composite panel component by improving the tensile strength, light weight, adhesion and fire-proof performances. The fiber composite panel cover (aramid-polyester ratios of 6:4 and 6.5:3.5) had a 2,348 MPa maximum tensile strength and a 1.8% maximum elongation. The filler that contained the nano-composite material and adhesive had a 4 MPa maximum tensile shear adhesive strength. In addition, the nano-composite filler was 30% lighter than the normal portland cement

• Journal of the Korea institute for structural maintenance and inspection
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• v.18 no.3
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• pp.160-166
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• 2014

In this research, as a measure of reducing energy lost through external wall, we used Glass Hollow Micro Sphere (HMS) to improve insulation performance to structural concrete. The following is a result of experimenting concrete using HMS. As usage of HMS, decrease in slump arose and it is judged as a need of using superplasticizer. Replacement ratio increasing more and more, amount of air showed tendency to decrease and compressive strength decreased for interfacial adhesion had not been formed. as replacement ratio and unit volume decreased. It appears that thermal conductivity decreased about 30.0~46.5 percent as compared with normal weight concrete.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2002.11a
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• pp.163-166
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• 2002

We investigated structural and electrical properties of Metal-Oxide-Semiconductor(MOS) structure using Hafnium $oxide(HfO_{2})$ as high-k gate dielectric material. $HfO_{2}$ films are ultrathin gate dielectric material witch have a thickness less than 2.0nm， so it is spotlighted to be substituted $SiO_{2}$ as gate dielectric material. In this paper We have grown $HfO_{2}$ films with pt electrode on P-type Silicon substrate by RF magnetron sputtering system using $HfO_{2}$ target and oserved the property of semiconductor-oxide interface. Using pt electrode, it is necessary to be annealed at ${300^{\circ}C}$. This process is to increase an adhesion ratio between $HfO_{2}$ films with pt electrode. In film deposition process, the deposition time of $HfO_{2}$ films is an important parameter. Structura1 properties are invetigated by AES depth profile, and electrical properties by Capacitance-Voltage characteristic. Interface trap density are measured to observe the interface between $HfO_{2}$ with Si using High-frequency(1MHz) C-V and Quasi - static C-V characteristic.

• Polymer(Korea)
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• v.35 no.1
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• pp.87-93
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• 2011

We developed a fluorene-containing multifunctional binder polymer for LCD color filter resist, and employing the binder polymer, carbon black based black photoresist (CBR) was prepared in order to apply it to the black matrix (BM). To obtain the multifunction of the binder polymer, we synthesized bisphenol fluorene epoxy acrylate-containing unsaturated polyester and identified the binder polymer structure with $^1H$ NMR, GPC and FTIR. The corresponding BFEA-polyester binder polymer was compared with the commercially available acryl binder toward the application to the CBR. From the BM lithography test, we found that the synthesized BFEA-polyester binder had better photocrosslinking capability and alkali solubility. In addition, the newly developed binder gave a good process margin, good resolution and adhesion property on a glass substrate.

• Macromolecular Research
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• v.17 no.7
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• pp.458-463
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• 2009

Polyurethane (PU) is widely used as a cardiovascular biomaterial due to its good mechanical properties and hemocompatibility, but it is not adhesive to endothelial cells (ECs). Cell adhesive peptides, GRGDS and YIGSR, were found to promote adhesion and spreading of ECs and showed a synergistic effect when both of them were used. In this study, a surface modification was designed to fabricate an EC-active PU surface capable of promoting endothelialization using the peptides and poly(ethylene glycol) (PEG) spacer, The modified PU surfaces were characterized in vitro. The density of the grafted PEG on the PU surface was measured by acid-base back titration to the terminal-free isocyanate groups. The successful immobilization of pep tides was confirmed by amino acid analysis, following hydrolysis, and contact angle measurement. The uniform distribution of peptides on the surface was observed by scanning electron microscopy (SEM) and atomic force microscopy (AFM). To evaluate the EC adhesive property, cell viability test using human umbilical vein EC (HUVEC) was investigated in vitro and enhanced endothelialization was characterized by the introduction of cell adhesive peptides, GRGDS and YIGSR, and PEG spacer. Therefore, GRGDS and YIGSR co-immobilized PU surfaces can be applied to an EC-specific vascular graft with long-term patency by endothelialization.