• Title/Summary/Keyword: Adaptive Plan

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췌장암 MRgART시 복부가스용적 변화에 의한 선량전달오류 원인 분석 (Analysis of the cause of dose delivery errors due to changes in abdominal gas volume during MRgART pancreatic cancer)

  • 하민용;손상준;김찬용;이제희
    • 대한방사선치료학회지
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    • 제32권
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    • pp.73-83
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    • 2020
  • 목 적: 본 연구에서는 췌장암 환자 MRgART(Magnetic Resonance-guided Adaptive Radiation Therapy)시 복부가스용적변화로 인하여 Image fusion 과정에서 생길 수 있는 조직과 가스의 전자밀도 매칭오류를 확인하고 그에 따른 선량 변화와 치료시간에 미치는 영향을 확인해 보고자 한다. 대상 및 방법: 본원에서 ViewRay MRIdian System (Viewray, USA)를 이용하여 MRgART를 시행한 췌장암 환자 중 최초 simulation시와 비교하여 복부가스용적감소가 발생한 환자를 대상으로 Initial plan과 복부가스 전자밀도를 수정한 AGC(Abdominal gas correction) plan의 PTV와 OAR선량을 비교하였고, 총4회 Adaptive 치료에서 환자의 Beam ON(%)을 확인하여 복부가스용적이 치료시간에 미치는 영향을 확인해 보았다. 결 과: Initial plan에서의 Mean, Minimum, Maximum 선량과 AGC plan의 Mean, Minimum, Maximum 선량평균값을 비교하였을 시 OAR에서는 -7~0.1%의 선량차이를 보였으며 평균 0.16% 감소하였고, PTV에서는 4.5~5.5%의 선량이 감소하였으며 평균 5.1%의 선량이 감소하였다. Adaptive치료 시 복부가스용적이 증가할수록 Beam ON(%)이 감소하였다. 결 론: Initial plan과 Adaptive plan간 복부가스용적 변화는 Adaptive plan시 전자밀도매칭 오류로 이어질 수 있으며 이는 PTV와 주변OAR의 선량분포를 변화시키므로 Adaptive plan시 영상 fusion 과정에서 가스용적을 보정한 정확한 전자밀도매칭은 필수적인 요소이다. 또한 복부가스용적이 커질수록 Beam ON(%)이 감소하여 환자의 Motion error로 인한 치료시간이 증가될 수 있다. 따라서 MRgART시에는 전자밀도매칭을 확인하고 복부가스의 가변성을 최소화 하여야 한다.

Intelligent Test Plan Metrics on Adaptive Use Case Approach

  • Kim, R. Young Chul;Lee, Jaehyub
    • International Journal of Fuzzy Logic and Intelligent Systems
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    • 제2권1호
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    • pp.70-77
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    • 2002
  • This paper describes a design driven approach to drive intelligent test plan generation based on adaptive use case (3,5). Its foundation is an object-oriented software design approach which partitions design schema into design architecture of functional components called “design component”. A use case software development methodology of adaptive use case approach developed in I.I .T is employed which preserves this unit architecture on through to the actual code structure. Based on the partition design schema produced during the design phase of this methodology, a test plan is generated which includes a set of component and scenario based test. A software metric is introduced which produces an ordering of this set to enhance productivity and both promote and capitalize on test case reusability, This paper contains an application that illustrates the proposed approach.

복원된 양재천에서 복원 효과 평가 및 평가 결과에 기초한 개선방안 (An Evaluation on Restoration Effect in the Restored Yangjae Stream and the Improvement Plan Based on the Result)

  • 김아름;김동욱;임봉순;설재원;이창석
    • 생태와환경
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    • 제53권4호
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    • pp.390-407
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    • 2020
  • This study was carried out to evaluate the restoration effect in the restored Yangjae stream and to draw up an adaptive management plan based on the results. As the result of evaluation on the restoration effect, the restored Yangjae stream was evaluated with low naturalness in both terms of the morphology of the stream and the composition and spatial distribution of vegetation. The diverse functional groups were introduced in the vegetation restoration, but the flooding regime, which is significant in the spatial distribution of riparian vegetation, were not correctly reflected. Exotic species or species that were not ecologically suitable for the location were introduced on the embankment and thus a measure to improve those problems is required. As the ecological principle was not reflected in the restoration plan, the stream was constructed as the double terrace structure. Therefore, the width of the waterway was narrowed further, and the waterfront was not designed to accommodate changes from flooding disturbance, making the micro-topography of the stream simpler and the naturalness lower. The adaptive management plan was prepared to improve those problems, and a plan for creating an ecological network was recommended to enhance the restoration effect.

수정 모드해석방법을 이용한 비대칭 벽식 구조물의 내진성능평가 (Seismic Assessment of Plan-irregular Wall Structures using Adaptive Modal Analysis)

  • 하태휴;홍성걸
    • 한국지진공학회:학술대회논문집
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    • 한국지진공학회 2006년도 학술발표회 논문집
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    • pp.589-596
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    • 2006
  • Torsional behavior of eccentric structures under seismic loading may cause stress and/or strain concentration, which result in the failure of the structures in an unexpected manner. This study propose how to assess the seismic capacity of plan-irregular RC wall structures. The seismic capacities ate expressed in terms of lateral displacement capacity of each wall. The seismic demands for displacement are assessed by so called displacement-based design approach. Those seismic capacity and demands are combined D-R coordinate, which is made up of lateral displacement and rotation angle. To expand these concepts to the inelastic region the adaptive modal analysis method is used. In addition, the failure mechanisms including torsional failure are defined on D-R coordinate. Finally, seismic assessments of two 3-story plan-irregular wall structures ate presented.

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케이스기반플랜기법에 의한 적응력있는 레슨플렌생성기 (An Adaptive Lesson Plan Generator Based on Case-Based Planning)

  • 이재인
    • 인지과학
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    • 제4권2호
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    • pp.85-114
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    • 1994
  • 지능형 교수 시스템(ITS:lntelligent Tutoring System)의 개발에 관한 연구에서 중요한 분야 중 하나의 교수법의 제어에 관한 연구이다. 즉 전체 학습목적 또는 학습주제의 선정(curriculmplan),선정된 학습목적에 적합한 레슨플랜(lesson plan),자연스런 대화진행(discourse plan) 방법에 관한 연구이다.본 논문에서는 위의 세가지 플랜 중 레슨플랜에 케이스 기반 플랜기법(casebased planing)을 적용하여 생성하는 방법을 제안하였다.기존의 레슨플랜생성기는 학습목적이 결정될 때마다 그에 적합한 레슨플랜을 생성하였다.이와달리 본 연구에서는 이미 기억된 플랜이 있으면 그 플랜을 그대로 사용하거나 수정하여 사용하고 기억된 플랜이 없으면 새로 생성할 수 있는 학습목적에 적응력 있는 레슨 플랜생성기를 개발하였다.연구의 대상으로는 미적분학의 부정적분으로 하였고 제시된 문제의 일반형을 유추하기 위하여 기술언어와 커리큘럼트리(curriculum tree)를 고안하였다.본 연구결과는 다른 분야 ITS의 레슨플랜생서기 개발에 이용할 수 있으며 또한 적분을 교육하는 실제 학습현장에서도 사용될 수 있을 것이다.

강남세브란스병원 토모테라피를 이용한 치료환자의 130예 통계분석 및 경험 (Experiences of the First 130 Patients in Gangnam Severance Hospital)

  • 하진숙;전미진;김세준;김종대;신동봉
    • 대한방사선치료학회지
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    • 제20권1호
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    • pp.45-53
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    • 2008
  • 목 적: 본원에 2007년 10월에 설치된 토모테라피를 이용하여 치료한 환자 130명에 대하여 치료의 통계적 특성을 분석하여 종양의 부위별, 종양표적체적의 변화, 전체치료시간(overall treatment time), 초고압전산화단층촬영(Megavoltage computed tomography; MVCT)을 이용한 환자의 이동 값, 종양의 크기 변화에 따른 보정치료계획(Adaptive plan) 필요성 등에 대한 통계를 분석하여 알아보고자 한다. 대상 및 방법: 본원에서 2007년 10월부터 2008년 8월까지 토모테라피를 받은 130명의 환자를 대상으로 조사하였다. 환자의 평균 연령은 53세(최소 25세, 최고 83세)이고, 치료 부위별로 두경부(22명), 흉부(47명), 복부(25명), 골반부(11명), 골격계(25명) 로 나누었으며 MVCT는 2,702번의 총 분할조사를 치료 전 100% 시행하였고 종양의 크기변화가 큰 27명은 보정치료계획을 시행하였다. 또한 획득된 MVCT와 kV-CT를 일치시킨 후 이동된 값(X, Y, Z, roll, vector)을 치료부위와 사용된 고정기구의 평균 오차범위를 조사하였고 위치잡이(set up), MVCT, 평균 전체치료시간, 표적체적(target volume; TV)을 조사하였다. 결 과: 분석결과 환자가 카우치에 누워있는 평균시간은 22.8분, 평균 치료시간은 13.46분, 평균 보정계수(mm) X=-0.7, Y=-1.4, Z=5.77, roll=0.29, vector=8.66으로 평균 육안적종양체적(gross tumor volume; GTV)=229 $cm^3$, 평균 임상표적체적(clinical tumor volume; CTV)=564 $cm^3$으로 나타났다. 흉부, 복부, 골격계 치료환자보다 두경부 환자의 이동된 vector값이 2.96 mm적음을 알 수 있었다. 치료부위별 이동된 vector값이 두경부>골격계>복부>흉부>골반부 순서로 나타났다. 또한, 보정치료 계획을 시행한 환자는 27명, 종양이 길거나 다발성 종양환자는 39명이며 치료 시 1개의 치료계획으로 치료할 때 전체치료시간은 32분, 2개의 치료계획으로 나누어 치료 시에는 각각 21분, 19분으로 총 40분 소요되는 것을 알 수 있었다. 결 론: 고정용구의 사용과 더불어 MVCT의 적용으로 더욱 정확한 세기조절방사선치료(intensity modulated radiation therapy; IMRT)를 할 수 있었다. 또한 매일 영상을 통해 종양의 변화를 확인하여 보정치료계획을 할 수 있었으며 종양이 길거나 또는 다발성 종양, 손상위험장기(organ at risk; OAR) 근처의 치료와 급격한 선량분포의 변화를 주어야 하는 복잡한 치료를 가능하게 하였다.

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적응형(適應形) 회계(會計)시스템에 의한 마아케팅 부문(部門)의 예산관리(豫算管理) 모형(模型) (A Bugetary Management Pattern Marketing Based on The Adaptive Accounting Control System)

  • 박대규
    • 산학경영연구
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    • 제2권
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    • pp.171-204
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    • 1989
  • The adaptive accounting control system can be regarded as an realistic control system which can adapt itself to uncertain enviromental changes. It has characters that can measure the extend to which we attain our goals and give intelligence, which is essential to planning for the future and for decision making. The budget should present the aim of the compilation of the budget and synthesize the limit through the systematic plan about the utilization of resources, because is a financial plan that is used as estimate of future management operations and as a control of it. If we would like to make good use of this business budget as a tool for planning, we should try to opimize all over the business by relating business operation as far as the effective use of the economic resources in business and the supplying of it are concerned and financial budgets to the responsibility unit center. As this paper is about the budgetary management pattern of marketing based on the adaptive accounting control system, I shall begin with a description of the feature and role of responsible accounting system in management accounting. I shall also deal with the Ex ante accounting system and the Ex post optimum accounting system which are essential to the control stage of business budgeting. And finally, accounting to the control process of adaptive accounting system that fit in with the reality, I shall design a budgetary management pattern of marking section. I wish this paper would be helpful to the activity of budgetary management. A budget is an important step of diverging point. Consequently, when we set up a budgetary pattern based on the adaptive accounting system as far as the control accounting is concerned. I believe that the step of responsible accounting will be a more elaborate and scientific step of management.

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Impact of Adaptive Radiotherapy on Locally Advanced Head and Neck Cancer - A Dosimetric and Volumetric Study

  • Dewan, Abhinav;Sharma, SK;Dewan, AK.;Srivastava, Himanshu;Rawat, Sheh;Kakria, Anjali;Mishra, Maninder;Suresh, T;Mehrotra, Krati
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권3호
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    • pp.985-992
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    • 2016
  • Objective of the study is to evaluate volumetric and dosimetric alterations taking place during radiotherapy for locally advanced head and neck cancer (LAHNC) and to assess benefit of replanning in them. Materials and Methods: Thirty patients with LAHNC fulfilling the inclusion and exclusion criteria were enrolled in a prospective study. Planning scans were acquired both pre-treatment and after 20 fractions (mid-course) of radiotherapy. Single plan (OPLAN) based on initial CT scan was generated and executed for entire treatment course. Beam configuration of OPLAN was applied to anatomy of interim scan and a hybrid plan (HPLAN30) was generated. Adaptive replanning (RPLAN30) for remaining fractions was done and dose distribution with and without replanning compared for remaining fractions. Results: Substantial shrinkage of target volume (TV) and parotids after 4 weeks of radiotherapy was reported (p<0.05). No significant difference between planned and delivered doses was seen for remaining fractions. Hybrid plans showed increase in delivered dose to spinal cord and parotids for remaining fractions. Interim replanning improved homogeneity of treatment plan and significantly reduced doses to cord (Dmax, D2% and D1%) and ipsilateral parotid (D33%, D50% and D66%) (p<0.05). Conclusions: Use of one or two mid-treatment CT scans and replanning provides greater normal tissue sparing along with improved TV coverage.

2013순천만국제정원박람회장 활용 계획 연구 (A Study on the Adaptive Reuse Plan for 2013 Suncheon Bay Garden Expo Site)

  • 조남훈;최정민
    • 농촌계획
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    • 제20권1호
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    • pp.161-173
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    • 2014
  • This study aimed to adaptive reuse plan a take advantage of Suncheon Bay Garden Expo 2013. Detailed objectives included: to identify and foster cultural and ecological resources in Suncheon Bay and Garden Expo Site; and to search and propose characterized program in the site for efficient utilization; and to revitalize a site for the vitalizations of the region where garden culture and garden industries for strengthening local competitiveness. The study was multi-phased. The first stage included basic surveys such as site status and environmental context analysis, and questionnaires and similar case studies, and the second stage was to review the direction of preliminary planning, develop associated industries and strategies for regional revitalization and review and incorporate project details. And the third stage aimed to develop a comprehensive plan from spatial plans and program plans and suggest plans to vitalize the operation of the site. The results of the study are as follows: First, the characterization strategy is 'healing experience tourism', 'healing garden', 'healing herbal care' are suitable for the site and regional revitalization. Second, the dimension of 2013 Suncheon Bay Garden Expo which was distinguished into four areas, in consideration of the characteristics and contents of the garden expo site for efficient operation and maintenance. Four area are as follows: the park oriented area, the experiential tourism oriented area, the existing conservation oriented area, and the area for associated industries. Third, the practice of private and public partnerships is needed in order to efficiently manage and operations. The significance of this study is that it is seeking to take advantage of the Garden Expo site and set the plan by existing resources and in consideration of local characteristics, in conjunction with area to envision and proposed management plan. Some problems are remained which have not been able to deal with details program and organization and financial planning programs for the operation of the site. This is for further study.