• 생명과학회지
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• 제27권8호
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• pp.896-901
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• 2017

본 연구는 $CCl_4$로 간 손상이 유도된 흰 쥐에서 호박산의 간 보호 효과 정도를 알아보기 위하여 수행되었다. 실험을 하기 위해 정상군(NOR), $CCl_4$처리군(CON), 보석호박섭취군(PCON-CS)군으로 나누어 1주일 적응기간을 가진 SD계 흰 쥐에 보석호박산을 일정한 시간에 200 mg/kg으로 3주간 투여하였다. 21일째 되는 날 마지막 투여 5시간 후에 정상군을 제외한 다른 그룹의 쥐에게 $CCl_4$를 복강주사 하였다. 보석호박섭취군은 $CCl_4$처리군에 비해 AST, ALT 활성은 93.20%, 88.76% 각각 억제효과를 보였고 MDA는 $CCl_4$처리군에 비해 85.17% 억제효과를 보였다. 보석호박섭취군의 SOD와 CAT는 $CCl_4$처리군에 비해 38.65%, 47.99% 증가효과를 보였다, 결론적으로 AST, ALT 활성도와 MDA 수치는 보석호박섭취군이 $CCl_4$처리군에 비하여 유의적으로 감소하여 정상군과 비슷한 수치를 나타내었고 SOD와 CAT효소 활성은 보석호박섭취군이 $CCl_4$처리군에 비하여 증가하였다. 또한 조직학적 관찰은 사염화탄소로 유도된 간경변과 세포괴사가 호박산에 의해 예방된 것으로 나타났다. 이 데이터들로 확인해보면 $CCl_4$로 유도된 간 독성을 호박산이 간을 보호하는 결과를 나타냈으며, 이는 호박산이 간 손상에 대한 보호 효과를 가진 약물의 소재개발에 이용 될 수 있다고 본다.

• 대한예방한의학회지
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• 제1권1호
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• pp.59-75
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• 1997

After examining the viewpoints of the mental cultivation of The yellow Emperor's Internal Bible(內徑), from the viewpoints of The yellow Emperor's Internal Bible, I studied the principles and methods of the mental cultivation(精神養生) which the Taoism School, the Confusian School and the past physicians proposed. And I studied the methods of mental cultivation of the child, the woman and the old by the differences of ages and sex. At the subject of health preservation(養生學) on the basis of concept of relevant adaptation of man to nature(天人相應思想), the mental cultivation(精神養生) was regard more important than the body cultivation(肉體養生) and it was considered that the success of health preservation depended on the state of mind. the basic principles of the mental cultivation is achivement of the mental internal keeping(精神內守) through the state of peace and tranquility without avarice and wild fancy(恬憺虛無). The ways of mental cultivation of the Taoism School, the Confusian School and the past physicians were in the category of The yellow Emperor's Internal Bible. 4. In the previous Jin dynasty(先秦時代), the important theoretical bases and practices to mental cultivation were made. In the Han dynasty(漢時代), the physicians attached importance to mental treaments. During the time from Sui dynasty to Tang Dynasty(隋唐時代), the mental cultivation was made perfect theoretically. During the Period from Song dynasty to Yuan Dynasty(宋元時代), Many methods of mental cultivation were newly created. During the Ming and the Qing Dynasties(明淸時代), the theory of health preservation and the methods of mental treaments were embodied. 5. Studying the mental cultivation by the differences of ages, the childhood(小兒期) is the spring of life. So the mental cultivation of this period put importance to the cultivation of Sh ng(養生). And the youth(靑年期) is the summer of life. So the mental cultivation of this period pill importance to the cultivation of Ch'ang(養長). And the middle age(中年期) is the autumn of life. So the mental cultivation of this period put imporance to the cultivation of Shou(養收). And the old age(老年期) is the winter of life. So the mental cultivation of this period put importance to the cultivation of Tsang(養藏). Studying the mental cultivation by the differences of sex, the man must do the mental cultivation through the dynamic nature(性情) of Yang(陽) and the woman must do the mental cultivation through the static nature of Yin(陰).

• 한국보건간호학회지
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• 제15권1호
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• pp.148-156
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• 2001

Data were collected using questionnare to 102 post-mastectomy patients visiting the out-patient department at Catholic University St. Mary Hospital and Kang Nam St. Mary Hospital from October, 1998 to January, 1999 in order to provide the basic data for development of nursing intervention which can help patients' emotional and sexual adaptation to treatment outcome as well as increase quality of life by studying spouse support, sexual satisfaction and marital intimacy of patients. Spouse support and sexual satisfaction were measured with the tool developed by Soon-bok Jang (1989). Marital intimacy was measured with the tool developed by Waring (1984) and improved by Sook-nam Kim (1998). Data were analyzed using t-test, ANOVA, multiple comparison by Duncan. Pearson correlation coefficients, and stepwise multiple regression. The results were as follows ; 1. Spouse support in the group of 6 month or less post-operative period was higher than that of 13 to 36 month period. 2. Sexual satisfaction in the group college graduation or above was higher than that of high school and middle school graduation. 3. Marital intimacy in the group of 61 month or above post-operative period was higher than that of 6 month or less and 13 to 36 month period. 4. The higher spouse support results in the higher sexual satisfaction and the higher marital intimacy according to a positive correlation. 5. The main effective variable on marital intimacy was spouse support. and the effectiveness showed $31.09\%$, while it was $43.06\%$ including sexual satisfaction and post-operative period.

• 대한정형도수물리치료학회지
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• 제12권1호
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• pp.57-67
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• 2006

Musculoskeletal neck dysfunction syndromes are common in outpatient musculoskeletal pain practice. The underlying musculoskeletal and neurologic causes of pain are variable. In the management of these patients, it is important to accurately identify and treat these pain generators to optimize patient outcome. It is the purpose of this review to discuss three main categories of functional anatomy, the role of superficial/deep muscular system and the scientific evidence for optimal physical therapy intervention for cervical dysfunction. Specifically there is evidence of lowered microcirculation in the upper trapezius muscle, morphological signs of disturbed mitochondrial function which appears to be limited to type I fibers and an increased cross-sectional area of type I muscle fibers despite a lower capillary to fiber area ratio. In acute neck pain syndrome, changes in muscle activity of painful muscles may result from segmental and supraspinal inhibitory effects. Muscle activation is closely related to the control of joint movements and postures and it is difficult to separate the influence of the two components. Both the altered muscle recruitment patterns and altered kinematics appear to be a poor adaptation for pain of the head - neck region, as they are likely to result in increased compressive loading in the cervical spine, affecting muscles, articular structures such as zygapophyseal joints, connective tissues and neural tissues which are all peripheral generators of referred pain. The rectus capitus posterior minor muscle shows that it is one of the most important muscles of the suboccipital region. In this article, i reviewed the anatomy, neurophysiology, function and dysfunction as well as the treatment of cervical dysfunction.

• 문화기술의 융합
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• 제8권5호
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• pp.251-258
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• 2022

본 연구는 코로나19 팬데믹에서 간호대학생을 대상으로 회복탄력성의 정도를 확인하고 회복탄력성에 영향을 미치는 요인을 확인하기 위해 시도되었다. 연구참여자는 B시의 2개 대학 간호대학생 320명을 대상으로 하였다. 자료분석은 SPSS 22.0 프로그램을 이용하여 실수, 백분율, 평균, 표준편차, t-test, ANOVA, 피어슨 상관계수, 다중회귀분석으로 분석하였다. 대상자의 회복탄력성 평균은 3.78±0.61점이었다. 대상자의 회복탄력성은 그릿(r=.469, p<.001), 간호전문직관(r=.614, p<.001), 간호사 이미지(r=.552, p<.001)와 정적상관관계를 나타냈다. 대상자의 회복탄력성에 영향을 미치는 관련 요인은 그릿(β=.321 p<.001), 간호전문직관(β=.385, p<.001), 간호사 이미지(β=.165, p=.022)로 나타났고, 설명력은 47.3%로 나타났다. 본 연구결과를 통하여 코로나19 팬데믹에서 간호대학생의 회복탄력성 향상을 위해 그릿, 간호전문직관, 간호사 이미지의 향상이 필요함을 확인하였다.

• Journal of Information Technology Applications and Management
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• 제28권3호
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• pp.59-75
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• 2021

This study aims to establish a foundation for autonomous driving on campus and communication of abundant university information in the HCI environment in a VR environment where college freshmen can freely travel around campus facilities. The purpose of this study is to develop a three-dimensional VR-style campus tour system to establish a media environment to provide abundant university information guidance services to freshmen in non-face-to-face situations. This study designed a three-dimensional virtual reality campus tour system to solve the problem of discontinuity in which VR360 filming space does not lead to space like reality, and to solve many problems of expertise in VR technology by constructing an integrated production environment of tour system. We aim to solve the problem of inefficiency, which requires a large amount of momentum in virtual space, by constructing a GUI that utilizes the motion of the field of view focus. The campus environment was designed as a three-dimensional virtual reality using a three-dimensional graphic design. In non-face-to-face situations, college freshmen freely transformed the HMD VR device, smartphone, FPS operation mode of the gyroscope sensor. The design elements of the three-dimensional virtual reality campus tour system were classified as ①Visualization of factual experiences, ②Continuity of space movement, ③Operation, automatic operation mode, ④Natural landscape animation, ⑤Animation according to wind direction, ⑥Actual space movement mode, ⑦Informatization of spatial understanding, ⑧GUI by experience environment, ⑨Text GUI by building, ⑩VR360, 3D360 Studio Environment, ⑪Three-dimensional virtual space coupling block module, ⑫3D360-3D Virtual Space Transmedia Zone, ⑬Transformable GUI(VR Device Dual Viewer-Gyro Sensor Full Viewer-FPS Operation Viewer) and an integrated production environment was established with each element. It is launched online (http://vautu.com/u1) by constructing a GUI for free driving mode and college information screens to adapt to college life for freshmen, and designing an environment that can be used simultaneously by current media such as PCs, Android, and iPads. Therefore, it conducted user research, held a development presentation, a forum on excellence in university innovation support projects, and applied it as a system on the website of a particular university. College freshmen will be able to experience university information directly from the web and app to the virtual reality campus environment.

• 농촌의학ㆍ지역보건
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• 제35권2호
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• pp.134-150
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• 2010

본 연구는 국제결혼이주여성을 대상으로 다양한 학문분야에서 발표된 건강관련 선행연구 분석을 통하여 현재까지 진행된 연구들의 경향을 파악하고자 시도하였다. 국제결혼 이주여성을 대상으로 2004년 6월부터 2009년 6월까지 최근 6년간 발표된 국내 학회지 논문 및 학위논문 60편을 연구대상으로 선정하여 연구대상 논문의 일반적 특성, 저자의 전공분야, 건강영역별 주제어와 변수 및 주요변수의 측정도구를 분석하였으며 그 결과는 다음과 같다. 국제결혼이주여성 대상 논문 중 51편(84.9%)이 2007년 이후 발표되었으며, 발표형태는 석사논문 43편(71.7%)이 가장 높게 나타났다. 연구대상 논문 중 학회지 발표는 13편으로 한국가족복지학(3편, 23.1%)에 가장 많은 논문이 게재되었고, 석사학위논문은 사회복지학전공자가 25편(53.2%)으로 가장 많았다. 건강영역별로는 건강영역 2편(3.3%), 사회적 건강영역 18편(30.0%), 정신적 건강영역 36편(60.0%), 신체적 건강영역 4편(6.7%)이었다. 건강영역별 주제어는 사회적 건강영역에서의 주제어는 '적응'과 '의사소통' 2개이며, 정신적 건강영역의 주제어는 '결혼만족', '생활만족', '사회적지지', '스트레스', '우울', '부부갈등', '갈등' 등 7개였으며, 신체적 건강영역의 주제어는 '의료서비스기관 이용'과 '건강증진행위'로 나타났다. 연구대상 논문의 건강영역별 주제어에 따른 변수를 살펴보면, 건강영역 주제어의 변수는 삶의 질 2개, 사회적 건강영역의 주제어에 따른 변수는 적응 16개, 의사소통 5개이며, 정신적 건강영역 주제어 중 결혼만족 25개, 생활만족 11개, 사회적지지 3개, 스트레스 9개, 우울 25개, 부부갈등 25개였으며, 신체적 건강영역의 주제어에 따른 변수는 의료서비스기관 이용 6개, 건강증진행위 5개로 나타났다. 가장 많은 변수가 사용된 주제어는 변수가 25개인 결혼만족, 우울, 부부갈등으로 나타났다. 연구대상 논문의 건강영역별 주제어에 따른 주요변수의 측정도구 중 2회 이상 사용된 측정도구만을 제시한 결과, 건강 영역에서 주제어 '삶의 질'의 측정도구는 Campbell(1976)과 보건복지부(2005), 사회적 건강영역에서는 주제어 '적응'의 변수 중 문화적응의 측정도구 Sandhu & Asrabadi (1994), 정신적 건강영역에서는 주제어 '우울'의 변수 중 문화적응스트레스 측정도구 Sandhu와 Asrabadi(1994)가 가장 많이 사용되었다. 결론적으로 국제결혼 이주여성을 대상으로 한 논문은 최근 다양한 학문분야에서 다양한 주제들로 연구되고 있으나 대부분이 한국 내 정착과 관련된 근본적인 문제만을 다루고 있다. 그러나 국제결혼 이주여성에게 쉽게 적응하기 어려운 타문화권의 생활은 신체적, 정신적, 사회적 불건강상태를 초래할 수 있다. 즉, 본 연구의 주제어에서 알 수 있듯이 국제결혼 이주여성과 가족들에게 잠재적인 건강문제가 발생할 수 있음을 예측할 수 있다. 따라서 국제결혼 이주여성들의 한국 내 적응과정을 돕고 2차적으로 발생할 수 있는 건강문제를 예방하기 위하여 건강과 관련된 다각적인 연구 및 건강관리 방향을 모색할 필요가 있다고 사료된다.

• Nutrition Research and Practice
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• 제3권2호
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• pp.156-161
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• 2009

Hyperglycemia in the diabetic state increases oxidative stress and antioxidant therapy can be strongly correlated with decreased risks for diabetic complications. The purpose of this study is to determine antioxidant effect of garlic and aged black garlic in animal model of type 2 diabetes. The antioxidant activity of garlic and aged black garlic was measured as the activity in scavenging free radicals by the trolox equivalent antioxidant capacity (TEAC) assay. Three week-old db/db mice were fed AIN-93G diet or diet containing 5% freeze-dried garlic or aged black garlic for 7 weeks after 1 week of adaptation. Hepatic levels of lipid peroxides and activities of antioxidant enzymes were measured. TEAC values of garlic and aged black garlic were $13.3{\pm}0.5$ and $59.2{\pm}0.8{\mu}mol/g$ wet weight, respectively. Consumption of aged black garlic significantly decreased hepatic thiobarbituric acid reactive substances (TBARS) level compared with the garlic group which showed lower TBARS level than control group (p<0.05). Activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) of garlic and aged black garlic group were significantly elevated compared to the control group. Catalase (CAT) activity of aged black garlic group was increased compared with the control group. These results show that aged black garlic exerts stronger antioxidant activity than garlic in vitro and in vivo, suggesting garlic and aged black garlic, to a greater extent, could be useful in preventing diabetic complications.

• 한국콘텐츠학회논문지
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• 제17권4호
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• pp.169-178
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• 2017

이 논문에서 우리는 입학사정관제가 잘 정착되어지고 있는지를 알고자 한다. 이를 위해 입학사정관제도와 기존의 입학제도로 입학한 학생들 사이에 학교생활 만족도, 학업성취도, 졸업 후 진로의 세 가지 영역에 대해 비교 분석하였다. 본 연구는 2016년 4월 기준으로 졸업한 09학번과 10학번들 중에서 세가지 영역에 대한 자료를 모두 가지고 있는 404명을 대상으로 평균차이검정과 카이제곱 검정으로 분석하였다. 연구 결과 입학사정관제로 입학한 학생들은 세 가지 영역에서 모두 통계적으로 유의미한 차이가 없는 것으로 나타났다. 특히 졸업 후 진로에 영향을 미치는 요인은 학업성취도였으며, 학업성취도는 입학사정관제 선발 유무와는 상관이 없는 것으로 나타났다. 이는 2008년부터 입학사정관제 선도대학으로 선정되어 지속적으로 시행한 H대학이 그동안 입학사정관 제도를 성공적으로 정착시켰다고 볼 수 있다.

• 간호행정학회지
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• 제4권1호
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• pp.151-181
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• 1998

This study purports to find out the meanings of chemotherapy among cancer patients. The subjects of this study were selected from those patients who have taken chemotherapy at least twice at a hospital affiliated with a university. The twelve subjects agreed to join the present study and had no problem in communication with others. The data were collected through observations and interviews by the researcher. The phenomenological analysis method proposed by Giorgi was adopted for analyzing the data. The experiences of the subjects to chemotherapy were classified into 24 atributes. These attributes were also categorized into four groups such as hope, pain, fear, and ordea according to their meanings. The subjects expressed hope through the attributes such as "the wish for a new life." "the wish for healing." "the plasure form improvement of cancer." "the wish for being discharged form a hospital." "the interest in dietectic treatment." and "the trust in medical staff." Pain was represented by such attributes as "the physical pain", "the suffering from intravenous injection." "the discomfort of hospital environment." and "the economic burden." As for the attributes represention fear, "fear of being hospitalized." "tehr obscurity of uncertain situations." "the fear of side effects." "the fear of recurrence of cancer," "the lack of knowledge of the disease." Finally, nine attributes werw frouped to ordeal "the will endeavouring to recover cancer" "the adaptation to the present situation." "the giving up of being healthy," "the regret of the past life." "the recognition of significant others." "the physical changes." "the emotional changes." "the social changes." "the recollection of illness experiences." The above findings indicate that chemotherapy means hope, pain, fear, and ordeal to those cancer patinests under treatment. Hence, the nursing interventions for those cancer patients need to be directed to maintaining hope, alleviating pain and fear, and overcoming ordeal. There are some suggestions in achieving these goals : (1) the nurses caring for cancer patients need to understand the meaning of chemotherapy experienced by those patients, (2) a nursing specialty of intravenous injection needs to be developed, (3) interventions for providing emotional support should be devised, (4) nursing care should also be available to those cancer patients being dischaged at home.