• Title/Summary/Keyword: Activity state

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Preparation and Characterization of Core/Shell-type Ag/Chitosan Nanoparticles with Antibacterial Activity

  • Lin, Yue;Jing, Wang;Kang, Pan;Xiaoming, Zhang;Zhouping, Wang;Wenshui, Xia
    • Bulletin of the Korean Chemical Society
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    • v.32 no.4
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    • pp.1277-1281
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    • 2011
  • Making use of chitosan (CS) and ethylenediaminetetraacetic acid (EDTA) as a reaction system, CS-EDTA nanoparticles were synthesized through a facile counterion complex coacervation method. $Ag^+$ could enter porous CS nanoparticles synthesized with this method, allowing Ag nanoparticles within chitosan nanoparticles were synthesized by reducing silver nitrate with chitosan. Because of the noncovalent interaction between CS and EDTA, the EDTA could be easily removed via dialysis against water, and pure core/shell-type Ag/CS nanoparticles could be obtained. The nanoparticles showed higher antibacterial activity toward E. coli than the active precursor Ag nanoparticles and CS.

A study on Self-esteem and Subjective Evaluations to Work among Elderly Persons (노인의 일에 대한 주관적인 평가와 자아존중감 간의 관계)

  • 이신숙
    • Journal of Families and Better Life
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    • v.17 no.1
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    • pp.45-56
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    • 1999
  • The purpose of this study was to look into correlations between subjective evaluation on the work and self-esteem of the elderly so as to provide information for finding out ways of developing their self-esteem. The subjects of this study were 318 elderly persons in Chonnam and Kwangju city. The statistics used for data analysis were frequency percentage mean standard deviation reliability stepwise and multiple regression analysis through the SAS package program. the major findings of this study can be summarized as follows; 1) The self-esteem of elderly persons was 25,9 which was above the median 24. 2) According to the results related to subjective evaluations on the work among the elderly the positive correlation was by education level family situation economic state social activity level and health state while the negative correlation was by sex, age, and spouse. 3) According to the results related to subjective evaluations on the work among the elderly the positive correl tion was by worker identity job satisfaction quality of work time. 4) In model 1. variable affecting their self-esteem were health sate education level economic state health state age social activity level and sex. In Model 2, variables affecting their self-esteem were worker identity education level economic state age health state social activity level job satisfaction and sex. Especially self-estee of elderly was highly correlated with subjective evaluations on the work among the elderly persons.

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Isoflavanones from the Stem of Cassia siamea and Their Anti-tobacco Mosaic Virus Activities

  • Hu, Qiu-Fen;Niu, De-Yun;Zhou, Bin;Ye, Yan-Qing;Du, Gang;Meng, Chun-Yang;Gao, Xue-Mei
    • Bulletin of the Korean Chemical Society
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    • v.34 no.10
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    • pp.3013-3016
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    • 2013
  • Two new isoflavanones, (3R) 7,2',4'-trihydroxy-3'-methoxy-5-methoxycarbonyl-isoflavanone (1) and (3R) 7,2'-dihydroxy-3',4'-dimethoxy-5-methoxycarbonyl-isoflavanone (2), together with six known isoflavanones (3-8), were isolated from the stems of Cassia siamea. The structure of 1-8 was elucidated by spectroscopic methods including extensive 1D- and 2D-NMR techniques. Compounds 1, 2, 5-8 were evaluated for their anti-tobacco mosaic virus (Anti-TMV) activity. The results showed that compounds 1 and 6 showed potential anti-TMV activity with inhibition rates of 24.6% and 26.9%, respectively. Compounds 2, 5, 7, 8 also showed anti-TMV activity with inhibition rates in the range of 11.8-18.6%.

Optimization of Carbon Sources to Improve Antioxidant Activity in Solid State Fermentation of Persimmon peel Using Lactic Acid Bacteria

  • Hwang, Joo Hwan;Kim, Eun Joong;Lee, Sang Moo
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.32 no.4
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    • pp.361-368
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    • 2012
  • The present study was conducted to develop persimmon peel, a by-product of dried persimmon manufacturing, as a feed additive via lactic acid bacteria fermentation. Pediococcus pentosaceus, Lactobacillus plantarum, and three strains of Leuconostoc mesenteroides were used as a starter culture in the solid state fermentation of persimmon peel, and antioxidant activity and total polyphenol content were assessed. Leuconostoc mesenteroides KCTC 3100 showed high antioxidant activity (p<0.05), whereas Pediococcus pentosaceus showed high total polyphenol content (p<0.05). These two strains were thus selected as starter culture strains. Glucose, sucrose and molasses were used as variables for optimization and a total 15 experimental runs were produced according to Box-Behnken design. Regarding significant effects of variables, molasses showed linear and square effects on antioxidant activity of persimmon peel fermentation (p<0.05). In conclusion, optimum concentrations of glucose, sucrose, and molasses were determined to be 4.2, 3.9 and 5.3 g/L, respectively, using a response surface model. Antioxidant activity was also improved 2.5 fold after optimization.

Effects of Diet Composition on Digestive Activities of Enzyme in Lensky Sturgeon

  • Nevalyonny A. N.;Zaitsev V. F.;Korostelyov S. G.
    • Journal of Aquaculture
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    • v.9 no.2
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    • pp.167-168
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    • 1996
  • Experiments were conducted to determine the activities of protease and carbohydrase in growing lensky sturgeon fed with three different diets containing various concentrations of protein and carbohydrate. Neutral pretense activity from growing lensky sturgeon the protein diet (predo-minary, almost $100\%$ protein) was lower then those from fish fed the other diets during the experimental period. The results may indicate that the level of pretense activity is inversely related to the level of protein in the diets.

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Effects of chromium picolinate on fat deposition, activity and genetic expression of lipid metabolism-related enzymes in 21 day old Ross broilers

  • Chen, Guangxin;Gao, Zhenhua;Chu, Wenhui;Cao, Zan;Li, Chunyi;Zhao, Haiping
    • Asian-Australasian Journal of Animal Sciences
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    • v.31 no.4
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    • pp.569-575
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    • 2018
  • Objective: This experiment was conducted to investigate the effects of chromium picolinate (CrP) on fat deposition, genetic expression and enzymatic activity of lipid metabolism-related enzymes. Methods: Two hundred forty one-day-old Ross broilers were randomly divided into 5 groups with 4 replicates per group and 12 Ross broiler chicks per replicate. The normal control group was fed a basal diet, and the other groups fed the same basal diet supplemented with 0.1, 0.2, 0.4, and 0.8 mg/kg CrP respectively. The experiment lasted for 21 days. Results: Added CrP in the basal diet decreased the abdominal fat, had no effects on subcutaneous fat thickness and inter-muscular fat width; 0.2 mg/kg CrP significantly decreased the fatty acid synthase (FAS) enzymatic (p<0.05); acetyl-CoA carboxylase (ACC) enzymatic activity decreased in all CrP groups (p<0.05); hormone-sensitive lipase (HSL) enzymatic activity also decreased, but the change was not significant (p>0.05); 0.4 mg/kg CrP group significantly decreased the lipoprotein lipase (LPL) enzymatic activity. FAS mRNA expression increased in all experimental groups, and the LPL mRNA expression significantly increased in all experimental groups (p<0.05), but not 0.2 mg/kg CrP group. Conclusion: The results indicated that adding CrP in basal diet decreased the abdominal fat percentage, had no effects on subcutaneous fat thickness and inter-muscular fat width, decreased the enzymatic activity of FAS, ACC, LPL and HSL and increased the genetic expression levels of FAS and LPL.

The Interaction of Cognitive Interference, Standing Surface, and Fatigue on Lower Extremity Muscle Activity

  • Hill, Christopher M.;DeBusk, Hunter;Simpson, Jeffrey D.;Miller, Brandon L.;Knight, Adam C.;Garner, John C.;Wade, Chip;Chander, Harish
    • Safety and Health at Work
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    • v.10 no.3
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    • pp.321-326
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    • 2019
  • Background: Performing cognitive tasks and muscular fatigue have been shown to increase muscle activity of the lower extremity during quiet standing. A common intervention to reduce muscular fatigue is to provide a softer shoe-surface interface. However, little is known regarding how muscle activity is affected by softer shoe-surface interfaces during static standing. The purpose of this study was to assess lower extremity muscular activity during erect standing on three different standing surfaces, before and after an acute workload and during cognitive tasks. Methods: Surface electromyography was collected on ankle dorsiflexors and plantarflexors, and knee flexors and extensors of fifteen male participants. Dependent electromyography variables of mean, peak, root mean square, and cocontraction index were calculated and analyzed with a $2{\times}2{\times}3$ within-subject repeated measures analysis of variance. Results: Pre-workload muscle activity did not differ between surfaces and cognitive task conditions. However, greater muscle activity during post-workload balance assessment was found, specifically during the cognitive task. Cognitive task errors did not differ between surface and workload. Conclusions: The cognitive task after workload increased lower extremity muscular activity compared to quite standing, irrespective of the surface condition, suggesting an increased demand was placed on the postural control system as the result of both fatigue and cognitive task.

Preliminary Mechanistic Study on the Trachea Smooth Muscle Relaxant Activity of Aqueous Leaf Extract of Tridax Procumbens in Male Wistar Rats

  • Salami, Shakiru Ademola;Salahdeen, Hussein Mofomosara;Anidu, Babatunde Shuaib;Murtala, Babatunde Adekunle;Alada, AbdulRasak Akinola
    • Journal of Pharmacopuncture
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    • v.25 no.3
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    • pp.209-215
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    • 2022
  • Objectives: Aqueous leaf extract of Tridax procumbens (ALETP) has potent relaxant activity. However, this relaxant activity in respiratory smooth muscle remains uninvestigated. This study investigates the effect of ALETP on the contractile activity of tracheal smooth muscle (TSM) in adult male Wistar rats. Methods: Twelve male Wistar rats divided into 2 groups and were treated with either 100 mg/kg of ALETP (ALETP treatment group) or vehicle (distilled water; control group) through oral gavage for 4 weeks. Dose responses of TSM from the 2 groups to acetylcholine (10-9 to 10-5 M), phenylephrine (10-9 to 10-5 M), and potassium chloride (KCl; 10-9 to 10-4 M) were determined cumulatively. Furthermore, cumulative dose responses to acetylcholine (10-9 to 10-5 M) after pre-incubation of TSM with atropine (10-5 M), L-NAME (10-4 M), indomethacin (10-4 M), and nifedipine (10-4 M), were determined. Results: Treatment with ALETP substantially inhibited TSM contraction stimulated by cumulative doses of acetylcholine, phenylephrine, and KCl. Furthermore, preincubation of TSM from the 2 groups in atropine significantly inhibited contractility in TSM. Incubation in L-NAME and indomethacin also significantly inhibited contractility in TSM of ALETP-treated rats compared to that of controls. Contractile activity of the TSM was also inhibited significantly with incubation in nifedipine in ALETP-treated rats. Conclusion: ALETP enhanced relaxant activity in rat TSM primarily by blocking the L-type calcium channel and promoting endothelial nitric oxide release. ALETP contains agents that may be useful in disorders of the respiratory tract.

Empathy and Mood Awareness Reflected in the Resting-State Brain Metabolic Activity in the Patients with Schizophrenia and Normal Subjects (안정상태 뇌 대사 활성도에 반영된 정신분열병 환자와 정상인에서의 감정이입과 기분인식 관련 뇌 영역)

  • Park, Il Ho;Chun, Jiwon;Jung, Young Chul;Seok, Jeong Ho;Park, Hae-Jeong;Lee, Jong Doo;Kim, Jae-Jin
    • Korean Journal of Biological Psychiatry
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    • v.14 no.2
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    • pp.129-141
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    • 2007
  • Objectives : Empathy has been conceptualized as the ability of emotional resonance and perspective-taking. Emotional awareness has been proposed as the basis of empathy. In this study we examined the relationship between empathy and mood awareness and their neural correlates in resting-state activity in normal controls and patients with schizophrenia. Methods : Empathy and mood awareness scale scores were compared between 29 patients with schizophrenia and 21 normal controls by voxel-based t-tests and voxel-based correlation analyses of resting-state $^{18}F$-FDG PET images. Results : Empathy and mood labeling scale scores were significantly decreased in schizophrenic patients. Mood monitoring was positively correlated with empathy score in normal controls, but not in schizophrenic patients. In normal controls, empathy was positively correlated with resting-state activities in the intraparietal sulcus and mood monitoring was positively correlated with the temporal pole, frontopolar cortex, inferior temporal gyrus, entorhinal cortex and the subgenual prefrontal cortex resting activities. The orbitofrontal cortex resting activity was positively correlated with mood monitoring-related subgenual prefrontal cortex activity in the normal controls. Patients with schizophrenia showed decreased orbitofrontal resting activity and loss of its correlations with mood monitoring-related regional activities. Conclusion : This study showed that alteration in the resting-state activity in schizophrenia may reflect dysfunctional empathy and distorted characteristic of emotional awareness. However, the resting-state activity may not reflect the relationship between emotional awareness and empathy.

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