• Proceedings of the KIEE Conference
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• 2007.07a
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• pp.1908-1909
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• 2007

The design of an intelligent toothbrush, capable of monitoring brushing motion, orientation through the grip axis, during toothbrushing is described. Inappropriate Toothbrushing styles, even in adults, sometimes cause dental problems, cavities, gingivitis, etc. This smart system provides user to monitor his or her brushing pattern using accelerometer and magnetic sensors for evaluation of toothbrushing style. Directional information of toothbrush with respect to earth's magnetic field and activity data were measured by a miniaturized low-power micro- controller, MSP430 and transmitted to personal computer by 2.4GHz radio transmitter, nRF2401. A personal computer provides an on-line display of activity and orientation measurements during toothbrushing. The signal trace is then analyzed to extract clinically relevant measurement. This preliminary study showed that the proposed monitoring system was conceived to aid dental care personnel in patient education and instruction in oral hygiene regarding brushing style.

• Proceedings of the Korean Society of Computer Information Conference
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• 2023.01a
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• pp.165-166
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• 2023

물환경정보시스템에서 하천의 수질을 측정한 자료를 대상으로 DMS(Digital Mosquito Monitoring System)가 설치된 위치와 수질 측정지 위치가 가까운 4개 지점에 대한 수질 측정 성분과 모기지수의 연관성을 분석하였다. 수질 기준 외 측정 성분과 모기지수의 상관관계는 총질소(T-N), 용존총질소(TDN), 인산염인이 연관성이 높은 것으로 나타났다. 이 중에서 인산염인은 모기지수와 양적 선형관계를 이루는데, 인산염은 수중에 부영양화를 일으키는 성분 중 하나다. 수질 측정지는 비료의 영향보다는 오수의 유입으로 인산염이 과잉공급되는 것으로 보였다. 따라서 매년 바뀌는 모기지수 산출식의 지연일자 데이터에 부영양화 지수를 넣음으로써 모기지수의 정확도를 보완할 수 있을 것으로 판단된다.

• The KIPS Transactions:PartD
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• v.18D no.2
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• pp.143-148
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• 2011

In this paper developed a wearable activity device and algorithm which can be converted into the real-time activity and monitoring by acquiring sensor row data to be occurred when a person is walking by using a tri-axial accelerometer. Test was proceeded at various step speeds such as slow walking, walking, fast walking, slow running, running and fast running, etc. for 36 minutes in accordance with the test protocol after wearing a metabolic test system(K4B2), Actical and the device developed in this study at the treadmill with 59 participants of subjects as its target. To measure the activity of human body, a regression equation estimating the Energy Expenditure(EE) was drawn by using data output from the accelerometer and information on subjects. As a result of experiment, the recognition rate of algorithm being proposed was shown the activity conversion algorithm was enhanced by 1.61% better than the performance of Actical.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.27 no.1
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• pp.17-27
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• 2001

A cell-based assay system for monitoring NF-$textsc{k}$B activity was developed to determine the influence of activated NF-$textsc{k}$B in human HaCaT cells. The pNF-$textsc{k}$B-SEAP-NPT plasmid that permits expression of the secreted alkaline phosphatase (SEAP) reported gene in response to the NF-$textsc{k}$B activity and contains neomycin phosphotransferase (NPT) gene for the geneticin resistance in host cells was constructed and transfected into human keratinocyte cell line HaCaT. Human HaCaT transfectant cells secreted the SEAP enzyme into the culture medium in a time-dependent manner until 72h. NF-$textsc{k}$B activities were measured in the SEAP reporter gene assay using a fluorescent detection method. The treatment of HaCaT cell transfectants with known antioxidants [e.g., N-acetyl-L-cysteine and vitamin C] showed inhibition of NF-$textsc{k}$B activity in a time-and concentration-dependent manner. The phorbol 12-myristate 13-acetate (PMA) known as a stimulator of NF-$textsc{k}$B expression demonstrated that it increased NF-$textsc{k}$B activity in a time- and concentration-dependent manner. This assay system could be used to determine the quantitative measurement of NF-$textsc{k}$B activity in the human skin and allow the screening of anti-inflammatory agents from various synthetic chemicals and natural products for dermatological purpose. Abbrevitions used: NF-$textsc{k}$B, nuclear factor kappa B; I-$textsc{k}$B, Inhibitory kappa B; SEAP, secreted alkaline phosphatase; NPT, neomycin phosphotransferease; PCR, polymerase chain reaction: dNTP, deoxynucleoside triphosphates; DMEM, dulbecco’s modified eagle medium; FBS, fetal bovine serum; PBs, phosphate-buffered saline; MUP, 4-methylumbellifery phosphate; NAC, N-acetyl-L-cysteine; DMSO, dimethyl sulfoxide; PMA, phorbol 12-myristate 13-acetate.

• Journal of Biomedical Engineering Research
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• v.3 no.2
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• pp.113-118
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• 1982

This paper presents a frequency modulated radio-telemetry, transmitter for monitoring and transmitting an exercise electrocardiogram (ECG) and respiration activity simultaneously on single carrier frequency in the standard FM broadcast band of 88-108 MHz. We have evaluated the performance of the FM telemetry transmitter which is proposed on the basis of an exercise ECG test in the treadmill.

• Journal of Electrochemical Science and Technology
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• v.12 no.1
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• pp.33-37
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• 2021

In electrochemical glucose sensing, the enhancement of the sensitivity and the response time is essential in developing stable and reliable sensors, especially for continuous glucose monitoring. We developed a method to increase the sensitivity and to shorten the response time for the sensing upon the appropriate addition of single wall carbon nanotube onto the osmium polymer-based hydrogel electrode. Also, the background stabilization is dramatically enhanced.

• Journal of KIISE
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• v.41 no.12
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• pp.1152-1159
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• 2014

In this paper, we presents a system to ensure the safety of residents through appropriate action or alarm in case the residents occurs an emergency situation and abnormal activity. We collect and analysis real-time data of living environment of the residents using video and sensor. The existing system have been determined by using only the sensor data it have several problems. Our system attach camera to solve the existing system problem. We use weighted difference image and motion vector. The existing system, it takes about 48 hours to determine that an abnormal activity occurs. However, our system takes less than 1 hour.

• Molecules and Cells
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• v.40 no.1
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• pp.73-81
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• 2017

The ${\gamma}$-secretase complex represents an evolutionarily conserved family of transmembrane aspartyl proteases that cleave numerous type-I membrane proteins, including the ${\beta}$-amyloid precursor protein (APP) and the receptor Notch. All known rare mutations in APP and the ${\gamma}$-secretase catalytic component, presenilin, which lead to increased amyloid ${\beta}$-peptide production, are responsible for early-onset familial Alzheimer's disease. ${\beta}$-amyloid protein precursor-like (APPL) is the Drosophila ortholog of human APP. Here, we created Notch- and APPL-based Drosophila reporter systems for in vivo monitoring of ${\gamma}$-secretase activity. Ectopic expression of the Notch- and APPL-based chimeric reporters in wings results in vein truncation phenotypes. Reporter-mediated vein truncation phenotypes are enhanced by the Notch gain-of-function allele and suppressed by RNAi-mediated knockdown of presenilin. Furthermore, we find that apoptosis partly contributes to the vein truncation phenotypes of the APPL-based reporter, but not to the vein truncation phenotypes of the Notch-based reporter. Taken together, these results suggest that both in vivo reporter systems provide a powerful genetic tool to identify genes that modulate ${\gamma}$-secretase activity and/or APPL metabolism.

• Food Science and Preservation
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• v.23 no.6
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• pp.859-865
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• 2016

Thise study aimed to determine the optimum antioxidant extraction conditions of dried Gugija (Lycium chinensis Mill). To determine the operational parameters, including ethanol concentration ($X_1$, 0~80%) and extraction time ($X_2$, 1~5 hr), a response surface methodology was applied to monitor brown color intensity, total phenolic compounds, ABTS radical scavenging activity, and $Fe^{2+}$ chelating activity. Coefficients of determinations ($R^2$) of the models were 0.8486~0.9214 (p<0.05~0.1) in dependent parameters. Brown color intensity of Gugija extracts reached a maximum of 0.75 (OD in 420 nm) under extraction conditions of 2.88 hr in 78.10% ethanol. Total phenolic compounds reached a maximum of $2,355{\mu}g$ under extraction conditions of 4.94 hr in 30.17% ethanol. ABTS radical scavenging activity was 13.83% at 4.61 hr and 16.21% ethanol. $Fe^{2+}$ chelating activity showed a maximum of 58.54% under extraction conditions of 3.39 hr in 0.76% ethanol. Optimum extraction conditions (5 hr extraction in 15% ethanol) were obtained by superimposing the contour maps with regards to total phenolic compounds, ABTS radical scavenging activity, and $Fe^{2+}$ chelating activity of dried Gugija. Maximum values of total phenolic compounds, ABTS radical scavenging activity, and $Fe^{2+}$ chelating activity under optimum extraction condition were $2,397{\mu}g$, 15.62% and 54.78%, respectively.

• Parasites, Hosts and Diseases
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• v.58 no.1
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• pp.99-102
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• 2020

Two-point mutations (V419L and L925I) on the voltage-sensitive sodium channel of bed bugs (Cimex lectularius) are known to confer pyrethroid resistance. To determine the status of pyrethroid resistance in bed bugs in Korea, resistance allele frequencies of bed bug strains collected from several US military installations in Korea and Mokpo, Jeollanamdo, from 2009-2019 were monitored using a quantitative sequencing. Most bed bugs were determined to have both of the point mutations except a few specimens, collected in 2009, 2012 and 2014, having only a single point mutation (L925I). No susceptible allele was observed in any of the bed bugs examined, suggesting that pyrethroid resistance in bed bug populations in Korea has reached a serious level. Large scale monitoring is required to increase our knowledge on the distribution and prevalence of pyrethroid resistance in bed bug populations in Korea. Based on present study, it is urgent to restrict the use of pyrethroids and to introduce effective alternative insecticides. A nation-wide monitoring program to determine the pyrethroid resistance level in bed bugs and to select alternative insecticides should be implemented.