• 생약학회지
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• 제35권1호통권136호
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• pp.62-79
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• 2004

Cell-scattering is a phenotypic change easily observed in most epithelial cells treated with Hepatocyte Growth Factor /scatter Factor (HGF/SF) or phorbol esters (PKC-activators). Recent studies have shown the possibilities to use as therapeutic materials of HGF/SF or non tumor promoting phorbol esters for liver disease, cancer and AIDS. In this study, we tested a cell-scattering activity of 534 methanol extracts from plants inhabiting in Korean peninsula using the phenotype-based assay system. Nine Active extracts were detected : Daphne genkwa, Daphne kiusiana, and Aleurites fordii showed high activity (+++), Euphorbia sieboldiana and Rhodotypos scandens showed medium activity (++), Sambucus sieboldiana var. pendula, Catalpa bignonioides, Sambucus sieboldiana and Lycoris squamigera showed low activity (+). Furthermore, the effects of these active materials in the culture cells were investigated with biochemical studies.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 2004년도 춘계 학술발표회 제16권1호
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• pp.572-575
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• 2004

A fundamental study was executed in order to evaluate quantitatively the effect on strength characteristic of concrete or mortar by fly ash. As a result, it was confirmed that the appropriate usage of fly ash is in existence comply with mix condition and characteristic of fly ash. And, we could evaluate the activity factor of fly ash. But, there are many problem in actual application because that the object of this study is only Method(2) out of the evaluation methods of activity factor proposed by CEN. Therefore, it is necessary to keep up an additional study.

• East Asian mathematical journal
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• 제28권2호
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• pp.173-195
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• 2012

The purpose of this study is to help for an in-depth understanding of their thinking process by observing and analyzing the response found by two elementary school students, Through this study, the following findings could be obtained. First, two students have a tendency trying to solve the complex situation at first. Second, we could know that it is an important factor in discovering the pattern to predict it. Third, we could know that the activity of reconstructing the data meaningfully is an important factor in discovering the pattern. Fourth, it is an important factor in finding the pattern to work organically the activity of predicting it with the activity of reconstructing the data meaningfully. We hope that this study offers the help for an in-depth understanding of students's thinking process.

• 한국데이타베이스학회:학술대회논문집
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• 한국데이타베이스학회 2008년도 연합학회학술대회
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• pp.307-320
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• 2008

본 연구는 관계중심적 지식관의 관점에서 지식공유의 영향 요인을 파악하고, 이 요인들이 실제로 지식공유에 긍정적인 영향을 미쳐서 지식성과활동을 향상 시키는지 알아보고자 한다. 독립변수인 관계적 요인은 신뢰, 개방적 의사소통, 협동으로 설정하였고, 지식공유의 영향을 받는 종속 변수인 지식활동성과는 지식품질과 지식경영사용자만족도로 설정하였다. 본 연구를 통해 조직경쟁력 향상을 위해서는 지식뿐만 아니라 그것을 사용하는 사람 및 주변 환경까지 관리할 필요가 있음을 제안한다.

• Natural Product Sciences
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• 제11권3호
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• pp.131-135
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• 2005

Methanolic extracts of ninety-five medicinal plants were screened for platelet-activating factor (PAF) receptor binding inhibitory activity using rabbit platelet. Alpinia officinarum, Belamcanda chinensis, Leonurus heterophyllus, Pinus densiflora, Polygonatum sibiricum and Sambucus williamsii showed significant inhibitory effects on the platelet-activating factor (PAF) receptor binding.

• 한국조경학회지
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• 제37권6호
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• pp.73-84
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• 2010

도시이미지 안에서 대표경관들은 그 도시를 상징하며 사람들에게 그 도시의 도시다움을 느끼게 해주는 도시정체성의 중요한 기간자원 역할을 하고 있다. 본 연구는 도시의 대표경관들이 어떠한 지각-인지의 조건들로 인해 대표성을 획득하게 되는지를 밝혀 보고자 하였다. 먼저 서울시를 중심으로 도시 대표경관과 관련된 기존 연구들을 종합하여 대표경관들을 도출하고, 그들 각각의 인지요인들을 설문을 통해 조사하여 유형별 요인별로 다각적 비교분석을 하였고, 그 결과를 향후 대표경관 계획 및 관리방안의 시사점으로 제시하였다. 연구의 기본방향은 특히 가시적 요인, 심미적 요인, 활동적 요인, 문화적 요인을 중심으로 진행되었다. 주목할 만한 사실은 다면적 요인의 분석에 의한 본 연구의 결과는 기존 연구에서의 대표경관의 인지 순위와는 큰 차이를 나타내고 있다는 것이고, 이에는 시민들의 문화적 요인에 대한 인식의 비중이 높아진 것이 원인으로 해석된다. 이러한 연구결과는 아직 기초적 연구결과이기는 하지만 후속 연구의 보완을 통해 향후 대표경관 계획과 관리의 새로운 관점을 제시할 수 있으리라 기대된다.

• 아태비즈니스연구
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• 제11권2호
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• pp.189-206
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• 2020

Purpose - The purpose of this study is to clarify the mediating effect of profitability and activity in the relationship between productivity and stock return, assuming that the productivity of the company will affect share prices with the parameters of profitability and activity. Design/methodology/approach - The study extracted productivity indicators, profitability indicators, activity indicators, and share price-related indicators from 1999 to 2018 of non-financial enterprises listed on the securities market, and then classified them into three factors: productivity (labor productivity LP, capital productivity CP), activity (TT), and profitability (net profit rate NI, operating profit ratio OI) through the factor analysis method, and analyzed the impact of each factor on the stock return through steps 1 to 3. Findings - The regression analysis shows that productivity has a significant positive effect on the stock return through the full mediating effect of profitability and activity. Research implications or Originality - In a situation where the relationship between productivity and profitability is not clear, this study is meaningful in that it has empirically analyzed that productivity has a positive effect on the stock return by mediating effects of profitability and activity.

• 한국미생물·생명공학회지
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• 제31권4호
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• pp.395-399
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• 2003

본 연구에서는 S. hindustanus ATCC 31218로부터 선별된 변이주를 사용하여 배양조건이 nebramycin 주요 생산물인 factor 2, factor 4, factor 5', kanamycin A 등의 구성비율과 역가에 미치는 영향을 조사하였다. 실험결과, nebramycin의 factor들이 구성비율은 온도 및 배지보다는 배양액량, 교반속도 등에 의해 크게 영향을 받는 것으로 나타났다. 따라서 플라스크와 발효조의 산소전달속도를 각각 측정하여 factor 5' 생산의 최적 산소전달조건을 검토한 결과, $0.50 mMO_2$/min으로 배양시 factor 5'의 역가가 가장 높았으며 구성비율도 70% 이상을 나타내었다. 한편 $0.9 mMO_2$/min 이상으로 배양시는 factor 2의 역가와 구성비율이 현저히 감소한 반면 factor 2의 역가와 구성비율이 급격히 증가하였다. 한편 본 연구에 사용된 변이주 S. hindustanus YHT-0001는 factor 5'의 역가는 16.4배, factor 5'구성비율은 약 11% 향상된 균주로 확인되었다. S. hindustanus 발효시 공급되는 산소량은 단지 hydroxyl기와 아미노기의 존재유무에 따라 구조가 결정되는 factor 5', factor 4, kanamycin A의 hydroxyl기 생성을 위한 산소공여자로 역할뿐 만 아니라 배당체 구조에 차이를 보이는 apramycin 생합성과정에 영향을 크게 준다고 사료되었다.

• Journal of Periodontal and Implant Science
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• 제29권4호
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• pp.785-804
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• 1999

The cell activities of bone metabolism is affected by growth factor rather than by hormone. The affects of growth factors on the bone activity were observed using various culture methods. Platelet-derived growth factor(PDGF) is produced from the well differentiated bone cell. It stimulates cell mitosis, synthesizes collagen in bone tissue and plays a role in healing response. The purpose of this study is to evaluate the effects that PDGF has on the activity and the proliferation of osteoblast by measuring the activity of alkaline phosphatase, the growth formation of calcified nodules, and osteocalcin production. In this study, HOS and ROS 17/2.8 osteoblastic cell line was used, along with variable concentrations of PDGF the were measured with osteoblastic proliferation. The cell proliferation of HOS and ROS 17/2.8 cells was stimulated dose- depentdently. Alakline phosphatase activity was significantly decreased by PDGF in osteoblastic cells. A number of small calcified nodules were observed in HOS cell treated with low concentrations(0.1, 0.4 ng/ml) of PDGF-BB and no significant difference from control group was found. High concentrations(10, 50 ng/ml) of PDGF suppressed calcified nodule formation. And osteocalcin production was inhibited with PDGF. These results suggest that PDGF stimulates the osteoblastic proliferation, whereas suppresses the individual cellular functions.

• 한국방사성폐기물학회:학술대회논문집
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• 한국방사성폐기물학회 2003년도 가을 학술논문집
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• pp.322-327
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• 2003

It is important to know the accurate radionuclide inventory of radioactive waste for the reliable management. However, estimation of radionuclide concentrations in drummed radioactive waste is difficult and unreliable because of difficulties of direct detection, high cost, and radiation exposure of sampling personnel. In order to overcome these difficulties, scaling factors (SFs) have been used to assess the activities of radionuclides that could not be directly analyzed. A radionuclide assay system has been operated at KORI site since 1996 and consolidated scaling factor method has played a dominant role in determination of radionuclides concentrations. However, some problems are still remained such as uncertainty of estimated scaling factor values, inaccuracy of analyzed sample values, and disparity between the actual and ideal correlation pairs and the others. Therefore, it needs to improve the accuracy of scaling factor values. The scope of this paper is focused on the improvement of accuracy and representativeness of calculated scaling factor values based on statistical techniques. For the selection of reliable activity determination method, the accuracy of estimated SF values for each activity determination method is compared. From the comparison of each activity determination methods, it is recommended that SF determination method should be changed from the arithmetic mean to the geometrical mean for more reliable estimation of radionuclide activity. Arithmetic mean method and geometric mean method are compared based on the data set in KORI system.