• Physical Therapy Rehabilitation Science
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• v.12 no.1
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• pp.56-61
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• 2023

Objective: Core training is a key exercise for conditioning and fitness programs, injury prevention, and more. This study aimed to find out the effect of adding dynamic core training, which is frequently prescribed in clinical practice, on dynamic balance and muscle activity compared to conventional static core training. Design: An experimental study Methods: This study is an experimental pilot study of prospective parallel design. Six healthy young adults were allocated to static core training group (SCG; crunch and plank) and blended group (BG; crunch, plank, and dead bug exercise) for two weeks to perform core training. Dynamic balance and muscle activity (erector spinae, rectus abdominis) were measured for all participants before and after core training. Results: All six healthy young adults enrolled completed the study. No significant difference was found before and after 6 sessions of core training in each group (P>0.05). Likewise, no significant difference was found in the results of the difference comparison between groups (P>0.05). Conclusions: In conclusion, in this experimental study, no difference was found when dynamic core training was added. Although the results before and after core training did not show improvement in dynamic balance and muscle activity, a randomized controlled trial is needed considering the results of previous studies and the limitations of this experimental study.

• Journal of the Korean Society of Physical Medicine
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• v.8 no.3
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• pp.417-424
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• 2013

PURPOSE: We investigated the relationship between the segment of erector spinae during a core stability exercise according to visual control. METHODS: The subjects of this study were 20 healthy students. An 8-channel electromyograph was used to measure muscle activities of the erector spinae by segment(cervical, thoracic and lumbar) during a core stability exercise according to visual control. The collected data were analyzed using the independent t-test and Pearson-test. RESULTS: The activity of the erector spinae for all segment was higher without the vision than with. The activity of right cervical erector spinae was significantly increased by increasing the activity of the left thoracic erector spinae during a core stability exercise with vision (r= .555). The activity of left thoracic erector spinae was significantly increased by increasing the activity of the left lumbar erector spinae during a core stability exercise without vision (r= .472). CONCLUSION: There was a positive correlation between the cervical and thoracic segment of erector spinae during a core stability exercise with vision. There was a positive correlation between the thoracic and lumbar segment of erector spinae during a core stability exercise without vision.

• PNF and Movement
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• v.15 no.2
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• pp.167-176
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• 2017

Purpose: This study investigated the effect of core and abdominal muscle-strengthening exercises on muscle activity in the lower extremity on unexpected perturbation. Methods: Twenty subjects were randomly divided into the core exercise group (n=10) or the abdominal muscles strengthening group (n=10). The two groups performed their exercises during three sessions a week for a total of four weeks. The muscle activity in the lower muscles (rectus femoris, biceps femoris, tibialis anterior, gastrocnemius) was assessed using surface electromyography (EMG) and normalized maximal voluntary isometric contraction (MVIC) before and after the exercises. Results: An increase in the tibialis anterior activity after the core and abdominal muscles strengthening exercises was found after four weeks. A significant difference in the pre- and post-exercise was found. The gastrocnemius muscle activity increased in the core exercise group more than the abdominal muscles strengthening group. However, the difference was not significant. Conclusion: The results of this study suggest that the core and abdominal muscles strengthening exercises increased the tibialis anterior muscle activity. It is expected to help make more balance ability that affect who has abdominal muscles weakness.

• BMB Reports
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• v.42 no.5
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• pp.281-285
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• 2009

Peroxisomes play an important role in cellular defense systems and generate secondary messengers for cellular communication. Saccharomyces cerevisiae containing oleate-induced peroxisomes were subjected to buffer-soluble extraction and two chromatographic procedures, and a protein with antifungal activity was isolated. The results of MALDI-TOF analysis identified the isolated protein as peroxisomal 3-ketoacyl-CoA thiolase (ScFox3). Purified yeast ScFox3 exhibited thiolase activity that catalyzed the thiolytic cleavage of 3-ketoacyl-CoA to acetyl-CoA and acyl-CoA. ScFox3 protein inhibited various pathogenic fungal strains, with the exception of Aspergillus flavus. Using ScFox3-GFP and PTS2 signal-truncated ScFox3M-GFP, we showed that only ScFox3-GFP, with an intact PTS2 peroxisome signal sequence, was able to translocate into peroxisomes. Yeast ScFox3 is a natural antifungal agent found in peroxisomes.

• Physical Therapy Korea
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• v.29 no.1
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• pp.64-69
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• 2022

Background: Gluteus medius muscle is important for the stability of hip joint. The sufficient core stability can be contributed to the performance of gluteus medius muscle in standing position. In addition, the external support may affect core stability in standing position. Objects: The purpose of this study was to investigated the effectiveness of the external support on the strength and muscle activity of hip abductor muscle during hip abduction in standing position in subjects without core stability. Methods: Fifteen subjects participated in this study. The subjects were evaluated by using the double-leg lowering with bent knees to measure the core stability. The strength and muscle activity of hip abductors was measured in standing position with the condition with and without external support using the tensiometer sensor and the surface electromyography. The paired t-test was used to investigate the difference between hip abductor strength and activity according to external support. The level of statistical significance was set at α = 0.05. Results: The hip abductor strength and muscle activity of gluteus medius muscle with external support were significantly greater than those without external support during hip abduction in standing position (p < 0.05). Conclusion: During hip abduction in standing position, the external support may be contributed to the improvement of the hip abductor strength and muscle activity of gluteus medius especially in the subjects without core stability.

• Journal of Life Science
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• v.13 no.5
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• pp.551-558
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• 2003

Hepatitis C Virus (HCV) is associated with a severe liver disease and increased frequency in the development of hepatocellular carcinoma. Overexpression of HCV core protein is known to transform fibroblast cells. Phospholipase D (PLD) activity is commonly elevated in response to mitogenic signals, and PLD has been also reported to be overexpressed and hyperactivated in some human cancer. The aim of this study was to understand how PLD can be regulated in HCV core protein-transformed NIH3T3 mouse fibroblast cells. We observed that in unstimulated state, basal PLD activity was higher in NIH3T3 cells overexpressing HCV core protein than in vector-transfected cells. Although expression of PLD and protein kinase C (PKC) in core protein-transformed cells was similar with that of control cells, phorbol 12-myristate 13-acetate (PMA), which is known to activate PKC, stimulated significantly PLD activity in core protein-transformed cells, compared with that of the control cells. PLD activity assay using PKC isozyme-specific inhibitor, and PKC translocation experiment showed that PKC-$\delta$ was mainly involved in the PMA-induced PLD activation in the core-transformed cells. Taken together, these results suggest that PLD might be implicated in core protein-induced transformation.

• Bulletin of the Korean Chemical Society
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• v.30 no.7
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• pp.1485-1488
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• 2009

A facile, seed-mediated preparation method of trimetallic Au@Pb@Pt core-shell nanoparticles is developed. Au nanoparticles are the template seeds onto which sequentially reduced Pb and Pt are deposited. The trimetallic core-shell structure is confirmed by UV-Vis spectroscopy, TEM and EDS analysis, and cyclic voltammetry. The trimetallic Au@Pb@Pt core-shell nanoparticles show high electrocatalytic activity for formic acid and methanol electrooxidation.

• Journal of Fisheries and Marine Sciences Education
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• v.20 no.2
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• pp.184-200
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• 2008

The purpose of this paper is to develop instructional activity support model for capstone design in order for improving creative engineering education. To do this, having extracted the core idea of capstone design, and elicited core learning activity process, and grasped core supportive factors according to each core learning activity process that elicited, an improved instructional design model for capstone design was then developed through formative evaluation with respect to the draft of the instructional system development model for capstone design. As to major research methods, case analysis, requirements analysis through interview, and formative evaluation by experts were employed, and then research studies were undertaken. The formative evaluation by experts was carried out for two hours in 2007, and the experts participated in the evaluation consisted of total 6 persons: two specialists of capstone design contents, two professionals in field works, and two expert instructional designers in education engineering. Interview results had been reflected in this research when developing final instructional design model for capstone design. The core learning activity process of the final instructional design model for caption design, which developed in this research, comprises following stages: (1) Team building $\rightarrow$ (2) Integrated meeting between industry and academy $\rightarrow$ (3) Analysis of tasks $\rightarrow$ (4) Clarification of tasks $\rightarrow$(5) Seeking solutions for issues $\rightarrow$ (6) Eliciting priority of solutions $\rightarrow$ (7) Designing solutions and construction $\rightarrow$ (8) Exhibiting outcomes and presentation $\rightarrow$(9) Gaining comprehensive insights Also, in the core learning activity process, supportive factors that support implementation of each step were presented having been categorized into facilitator (teacher, and professionals in field works), learner and tool, etc.

• Asian-Australasian Journal of Animal Sciences
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• v.19 no.5
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• pp.684-689
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• 2006

The present study examined the effects of Tween 80 on the attachment and hydrolytic activity of a cellulase enzyme against ball-milled cellulose (BMC), using the whole component (native CBH I) and the catalysis module (core CBH I) of carbohydrolase I purified from Trichoderma viride (Meicelase, Meiji Seika, Tokyo, Japan). The effects were evaluated as protein concentrations in the supernatant after mixing enzyme and substrate with Tween 80 at room temperature. Tween 80 decreased the adsorption of native CBH I and core CBH I onto BMC (p<0.001) and increased the amount of reducing sugars released from BMC by native CBH I (p<0.001). However, Tween 80 did not enhance the hydrolytic activity of core CBH I. Observations using SEM revealed that Tween 80 caused cellulose filter paper to swell and enhanced surface cracks and filaments caused by native CBH I but not by core CBH I. These results suggested that Tween 80 decreases enzyme adsorption to its substrate but enhances enzymatic activity.

• BMB Reports
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• v.30 no.4
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• pp.269-273
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• 1997

Heptocvte-specific expression induced by Hepatitis B virus (HBV) enhancer 2-core gene promoter was examined in various hepatocyte and non-hepatocyte cell lines. using non-viral and retroviral vector systems in which chloramphenicol acetyltransferase (CAT) is used as a reporter. The non-viral plasmid containing the HBV enhancer 2-core promoter exhibited 22 and 66% of CAT activities in hepatoma cell lines. HepG2 and Hep3B, respectively when compared with CAT activity expressed by CMV promoter. The CAT activities, however. were found to be marginal in other tested hepatoma cell lines as well as mouse primary hepatocytes and non-hepatocytes. The HBV enhancer 2 located upstream the CMV promoter did not affect the CMV promoter activity nor provided hepatocyte-specific expression. Transfection of retroviral plasmid DNA containing the HBV enhancer 2-core promoter as an internal promoter exhibited high and specific CAT expression in HepG2 and Hep3B cell lines but the activity value was 5 to 10 fold lower than the non-viral plasmid with identical promoter. These results suggest that the usage of HBV enhancer 2-core promoter for liver specific expression is limited to certain vectors and hepatocyte cell lines.