• Environmental Analysis Health and Toxicology
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• 제6권1_2호
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• pp.59-70
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• 1991

This study was performed to investigate the effect of olive oil diet on the immune response in ICR male mice. Experimental diets of 4 groups were fed ad libitum to the ICR male mice for 27 days. The results of this study were summarized as followings: 1. 10% Olive oil diet group as compared with the control diet group significantly decreased liver weight rate but significantly increased hemagglutination titer (HA), Arthus reaction, delayed type reaction (DTH), rosette forming cell (RFC), and phagocyte activity. 2. 20% Olive oil hypersensitivity diet group as compared with the control diet group significantly increased body weight gain, liver weight rate, and HA but significantly decreased Arthus reaction, DTH, RFC, phagocyte activity, and peripheral circulating white blood cell (WBC). 3. 30% Olive oil diet group as compared with the control diet group significantly increased liver weight rate but significantly decreased body weight gain, Arthus reaction, plaque forming cell (PFC), DTH, RFC, phagocyte activity, and WBC. The results showed that the increase of olive oil doses significantly decreased humoral and cellular immune responses, phagocyte activity, and WBC.

• 약학회지
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• 제46권1호
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• pp.58-62
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• 2002

The underlying mechanism by which the reflux of gastric juice elicits oesophagitis remaind unclear. To investigate inflammatory response to HCI in tissue of esophagus and lower esophageal sphincter experimental esophagitis was elicited by perfusion of 0.1 N HCI in cats. There was no difference in phospholipase $A_2$ (PLA$_2$) activity of tissue between control and esophagitis. Myeloperoxidase activity in esophagitis was significantly greater than that of control. However histamine content in esophageal mucosa of esophagitis was significantly smaller than that of control. These finding suggest that inflammatory response to HCI in esophagitis is related to changes of myeloperoxidase activity and histamine rather than change of PLA$_2$ activity.

• 한국환경보건학회지
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• 제21권1호
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• pp.78-85
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• 1995

Ornithine decarboxylase(ODC) is an indicate enzyme in carcinogenesis. We divided Sprague Dawley rats into six groups: control, electric field exposure, X-ray only irradiation, X-ray irradiation with electric field exposure group, Sr-90 injected group and Sr-90 and electric field complex exposure group. The ODC activity was measured in rat's bone marrow cell every week. The results were summarized as follows: The ODC activitied was increased in X-ray irradiated, Sr-90 injected and Sr-90 and electric field complex exposed group as compared with that of control(p<0.05). The ODC activity was increased comparing that of control neither in X-ray and electric field complex exposed group nor electric field only exposed group. This result suggests that the electric field doesn't have myeloid carcinogenicity and myeloid cancer incidence caused by ionized radiation is suppressed by electric field exposure.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2004년도 춘계종합학술대회
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• pp.454-458
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• 2004

본 논문에서는 시각 시스템의 민감도를 고려한 새로운 비디오 율제어 기법을 제안한다. 제안된 방식은 MPEG2 TM5 율제어 기법과 같이 3단계의 구조로 구성되어 있으나, 적응적 양자화를 위한 시각의 시-공간 민감도에 근거한 새로운 마크로블록 활성도 척도를 사용한다. 모의 실험을 통해 TM5 방식에서 사용된 공간 활성도보다. 제안된 시-공간 결합 활성도가 주관적, 객관적 화질 측면에서 우수함을 증명한다.

• 대한치과교정학회지
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• 제26권4호
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• pp.449-454
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• 1996

교정력에 의한 치아이동은 세포반응의 결과로 나타난다. 이에 힘의 양상에 따른 세포의 반응을 알아보고자 MC3T3-E1 세포를 24well 배양접시에 배양한 후 밀생상태가 되었을 때, incubator 속의 특수 제작된 사각상자에 배양 접시를 넣고 타이머에 연결된 Diaphram pump를 이용하여 $300gm/cm^2$의 압력을 10분간 가압후 10분간 가압이 중지되도록 한 간헐적 가압군과 지속적으로 가한 가압군으로 하여 각각 실험 24시간, 48시간, 72시간후의 alkaline phosphatase활성도를 대조군과 비교하여 다음과 같은 결과를 얻었다. 1. 가압 24시간 후에서는 각 군간에 alkaline phosphatase 활성도에 유의한 차이가 나타나지 않았다. 2. 가압 48시간 후에서는 간헐적 가압군과 지속적 가압군 모두 대조군 보다 alkaline phosphatase 활성도가 증가 되었다. 3. 가압 72시간 후에서는 간헐적 가압군의 alkaline phosphatase 활성도 증가가 대조군에 비하여 더욱 현저하였으나 지속적 가압군에는 대조군에 비하여 유의한 차이가 나타나지 않았다. 4. 가압 72시간 후에서는 간헐적인 가압군이 지속적인 가압군에 비하여 alkaline phosphatase의 활성도가 증가되었다. 5. 가암에 의한 세포의 뚜렷한 형태학적인 변화는 관찰되지 않았다.

• 대한전기학회논문지:전기기기및에너지변환시스템부문B
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• 제55권12호
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• pp.661-666
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• 2006

Interlocking signalling system plays key role as core system to manage railway operation. The core role of railway operation is to control routing, displaying signal and regulation for train. Interlocking system relate tightly to railway accident because collision and derailment is sometime taken place wrong route setting and signal displaying. Safety activity for interlocking system is inevitable to avoid the accident over its life cycle. The safety activity includes hazard identification and analysis, safety requirement allocation, safety plan, safety activity and ao on. The safety activity need a broad wide range work. In this paper, we concentrate on hazard identification for generic interlocking system and programmable electronic interlocking system and compare between two results. The hazards will be used for safety activity.

• Journal of Ginseng Research
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• 제5권1호
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• pp.49-55
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• 1981

The effects of total, protopanaxadiol-and protopanaxatriol-saponins on the in vitro activities of several enzymes in rat serum were observed Alkaline phosphatase activity was increased 61 % by total saponin and 46% by protopanaxatriol-saponin, compared to control group. While SCOT activity was slightly decreased by total saponin and protopanaxatriol- saponin, it was slightly increased by Protopanaxadiol-saponin And while SCPT activity was slightly decreased by total saponin, it was increased by protopanaxadiol-saponin and protopanaxatriol-saponin. Creatine phosphokinase activity had a tendency to be increased by protopanaxatriol-saponin. Lactate dehydrogenase activities were increased in three saponin treated groups, but those were nonignificant. Compared to the control group, lipase activity was increased by all saponin samples. It was increased 157% by total saponin The increase in lipase activity by total saponin corresponded with the decrease in serum t total lipid by total saponin .

• 약학회지
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• 제19권4호
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• pp.234-239
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• 1975

Protocollagen proline hydroxylase (PPH) activity in the course of rebound of rat carrageenin granuloma was assyed to investigate its relationship with collagen blosynthesis. The specific activity of PPH which was inhibited significantly by treatments with hydrocortisone acetate 93mg/kg/day, 3days) was recovered near to the normal level by 48hr after the cessation of the corticoid treatments. The total enzyme activity of the granuloma of treated group was not yet recovered even on the 3rd day, still showing a significant difference from control. PPH activity expressed in terms of granuloma cells between control and the drug treated group, however, was changed showing no apparent difference throughout the experimental period. These results suggested that the synthesis of protocollagen(collagen precursor) rather than PPH activity was directly affected by administration and withdrawal of corticoid.

• BMB Reports
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• 제28권6호
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• pp.490-493
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• 1995

We investigated the effect of hydrogen peroxide-treated metallothionein on the hepatic xanthine oxidase activity in vitro. When the metallothionein was preincubated with 1 mM of hydrogen peroxide, the activity of xanthine oxidase and type conversion were elevated dose-dependently by the addition of metallothionein into the reaction mixture. While increasing the treatment of hydrogen peroxide to the $50{\mu}g$of metallothionein, the xanthine oxidase activity and type conversion ratio were remarkably elevated dose dependently compared to the control. When cadmium ion was added to the reaction mixture, the increasing pattern of the enzyme activity was similar to the effect of hydrogen peroxide-treated metallothionein. DTT or penicillamine restored the increasing activity and type conversion of xanthine oxidase by the cadmium ion to the control level.

• 사상체질의학회지
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• 제24권4호
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• pp.62-74
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• 2012

Objectives : The purpose of this study is to investigate the effect of oral administration of Yongyukjowi-tang(YJT) on the immune activity in aged Sprague-Dawley rat(SD rat). Methods : SD rats were divided into three groups: Yongyukjowi-tang groups(YJT groups), distilled water groups(control groups) and Vitamin C groups(positive control groups) which were administered an oral dose(1ml/1day) to 6, 48 and 68 weeks old SD rats for four weeks. After four weeks, the number of total leukocyte, CD3+, CD4+, CD8+, and the level of cytokine (IL-2, IL-4, IL-10, IFN-${\gamma}$) were measured in spleen tissue of each SD rats. Results and Conclusions : 1) The number of total leukocyte significantly increased in 52 weeks old YJT group and 72 weeks old YJT group in comparison with those of the control group. 2) The number of CD3+ cell significantly increased in 72 weeks old YJT group in comparison with those of the control group and the positive control group. 3) The number of CD8+ cell significantly increased in 52 weeks old YJT group in comparison with those of the control group. 4) The level of IL-2 significantly increased in 72 weeks old YJT group in comparison with those of the control group and the positive control group. 5) The level of IL-4 significantly increased in 52 weeks old YJT group in comparison with those of the positive control group. These results suggest that oral administration of YJT has an effect on increase of immune activity in aged rat.