• Molecules and Cells
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• v.37 no.9
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• pp.656-663
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• 2014

Gintonin, a novel, ginseng-derived G protein-coupled lysophosphatidic acid (LPA) receptor ligand, elicits $[Ca^{2+}]_i$ transients in neuronal and non-neuronal cells via pertussis toxin-sensitive and pertussis toxin-insensitive G proteins. The slowly activating delayed rectifier $K^+$ ($I_{Ks}$) channel is a cardiac $K^+$ channel composed of KCNQ1 and KCNE1 subunits. The C terminus of the KCNQ1 channel protein has two calmodulin-binding sites that are involved in regulating $I_{Ks}$ channels. In this study, we investigated the molecular mechanisms of gintonin-mediated activation of human $I_{Ks}$ channel activity by expressing human $I_{Ks}$ channels in Xenopus oocytes. We found that gintonin enhances $I_{Ks}$ channel currents in concentration- and voltage-dependent manners. The $EC_{50}$ for the $I_{Ks}$ channel was $0.05{\pm}0.01{\mu}g/ml$. Gintonin-mediated activation 1 of the $I_{Ks}$ channels was blocked by an LPA1/3 receptor antagonist, an active phospholipase C inhibitor, an $IP_3$ receptor antagonist, and the calcium chelator BAPTA. Gintonin-mediated activation of both the $I_{Ks}$ channel was also blocked by the calmodulin (CaM) blocker calmidazolium. Mutations in the KCNQ1 $[Ca^{2+}]_i$/CaM-binding IQ motif sites (S373P, W392R, or R539W)blocked the action of gintonin on $I_{Ks}$ channel. However, gintonin had no effect on hERG $K^+$ channel activity. These results show that gintonin-mediated enhancement of $I_{Ks}$ channel currents is achieved through binding of the $[Ca^{2+}]_i$/CaM complex to the C terminus of KCNQ1 subunit.

• The Journal of the Korea institute of electronic communication sciences
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• v.11 no.2
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• pp.179-184
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• 2016

The electrical load testing system developed from this study was designed to control rated-capacity-testing or variable-load-testing in an active and precise manner and save electric energy during testing, and also to convert the saved electric energy through the electrical load testing system to grid line. As for the device under testing, it was designed to be applied to not only transformer, rectifier, voltage regulator, inverter which require grid voltage source but, also applied to electric power, aerogenerator, photovoltaic, hybrid generator, battery, etc. which do not require grid voltage source. The system was designed to return the power consumed during the testing to the grid line by connecting the synchronizing pwm inverter circuit to the grid voltage source, and was also made to enable the being-tested system from disuse of approximately 93.4% energy when compared to the conventional load testing system which has used the passive resistor.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2015.10a
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• pp.412-415
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• 2015

This paper presents a MPPT(Maximum Power Point Tracking) control CMOS interface circuit for vibration energy harvesting. The proposed circuit consists of an AC-DC converter, MPPT Controller, DC-DC boost converter and PMU(Power Management Unit). The AC-DC converter rectifies the AC signals from vibration devices(PZT). MPPT controller is employed to harvest the maximum power from the PZT and increase efficiency of overall system. The DC-DC boost converter generates a boosted and regulated output at a predefined level and provides energy to load using PMU. A full-wave rectifier using active diodes is used as the AC-DC converter for high efficiency, and a schottky diode type DC-DC boost converter is used for a simple control circuitry. The proposed circuit has been designed in a 0.35um CMOS process. The chip area is $950um{\times}920um$.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.9 no.3
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• pp.638-644
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• 2008

It is required small size electronic ballast to fullfill the design philosophy of miniaturizing in the application of slim lamps. However, the traditional magnetic ballasts operated at 50-60Hz have been suffered from noticeable flicker, high loss, large crest factor and heavy weight. In this study, in order to solve these problems, It was proposed for driving 35W Class fluorescent lamp in the new type of electronic ballast, which is composed of rectifier, active power factor corrector, series resonant half bridge inverter and piezoelectric transformer. A 35W class(T5 class) fluorescent lamp is driven to successful by the fabricated ballast with piezoelectric transformer. Experimental results, It is proposed to driving the lamp using a electronic ballast at operating frequency of $75{\sim}79kHz$ approximatively. It is operated after for 25 min that were obtained good results of the input power factor of 0.95 and efficiency of 86%, respectively.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2014.10a
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• pp.267-270
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• 2014

This paper presents a CMOS interface circuit for vibration energy harvesting. The proposed circuit consists of an AC-DC converter and a DC-DC boost converter. The AC-DC converter rectifies the AC signals from vibration devices(PZT), and the DC-DC boost converter generates a boosted and regulated output at a predefined level. A full-wave rectifier using active diodes is used as the AC-DC converter for high efficiency, and a schottky diode type DC-DC boost converter is used for a simple control circuitry. A MPPT(Maximum Power Point Tracking) control is also employed to harvest the maximum power from the PZT. The proposed circuit has been designed in a 0.35um CMOS process. The chip area is $530um{\times}325um$. Simulation results shows that the maximum efficiencies of the AC-DC converter and DC-DC boost converter are 97.7% and 89.2%, respectively. The maximum efficiency of the entire system is 87.2%.

• Journal of IKEEE
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• v.23 no.1
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• pp.143-150
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• 2019

The back-to-back HVDC asynchronous grid interconnect technology has problems of high harmonic generation, high cost, and low scalability. To solve this problem, research on asynchronous grid interconnect technology using VFT is actively being conducted. However, the reactive power due to the inductance component of the VFT is generated, and the problem of additional installation of the reactive power compensating facility is inevitably generated. Therefore, in this paper, we aim to solve the reactive power compensation problem of existing VFT by designing rectifier AC-DC converter, which is an essential element of the asynchronous grid connection system using VFT, to compensate reactive power as well as active power supply. The performance was verified through simulation.

• Journal of the Korean Society of Marine Environment & Safety
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• v.23 no.6
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• pp.739-745
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• 2017

Many studies have been conducted to reduce environmental pollution by ships and reduce fuel consumption. As part of this effort, research on power conversion systems through DC distribution systems that link renewable energy with conventional power grids has been pursued as well. The diode rectifiers currently used include many lower harmonics in the input current of the load and distort supply voltage to lower the power quality of the whole system. This distortion of voltage waveforms causes the malfunctions of generators, load devices and inverter pole switching elements, resulting in a large number of switching losses. In this paper, a controller is presented to improve DC output waveforms, the input Power Factor and the THD of an AFE type PWM rectifier used for PLL. DC output voltage waveforms have been improved, and the input Power Factor can now be matched to the unit power factor. In addition, the THD of the input power supply has been proven by simulation to comply with the requirements of IEEE Std514-2014.

• The Transactions of the Korean Institute of Power Electronics
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• v.8 no.1
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• pp.70-79
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• 2003

In this paper, T5 28-watt fluorescent lamp ballast using a piezoelectric transformer is fabricated and its characteristic is investigated. Developed electronic ballast is composed of basic circuits and blocks, such as rectifier part, active power factor corrector part, frequency oscillation part using microcontroller and feedback control, piezoelectric transformer and resonant half bridge inverters. The fabricated ballast uses to variable frequency methode in external so exciting that the frequency of piezoelectric transformer could be generated by voltage control oscillator using microcontroller(AT90S4433). The current of fluorescent lamp is detected by feedback control circuit. The signal of inverter output is received using Piezoelectric transformer, and then its output transmitted to fluorescent lamp. Traditional electromagnetic ballasts operated at 50-60Hz have been suffered from noticeable flicker, high loss, large crest factor and heavy weight. A new electronic ballast is operated at high frequency about 75kHz, and then Input power factor, distortion of total harmonic and lamp current crest factor are measured about 0.9!35, 12H and 1.5, respectively Accordingly, the traditional ballast is by fabricated electronic ballast using piezoelectric transformer and voltage control oscillator because of its lighter weight, high efficiency, economic merit and saving energy.

• Journal of IKEEE
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• v.20 no.1
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• pp.45-53
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• 2016

This paper presents a CMOS interface circuit for vibration energy harvesting with MPPT (Maximum Power Point Tracking). In the proposed system a PMU (Power Management Unit) is employed at the output of a DC-DC boost converter to provide a regulated output with low-cost and simple architecture. In addition an MPPT controller using FOC (Fractional Open Circuit) technique is designed to harvest maximum power from vibration devices and increase efficiency of overall system. The AC signal from vibration devices is converted into a DC signal by an AC-DC converter, and then boosted through the DC-DC boost converter. The boosted signal is converted into a duty-cycled and regulated signal and delivered to loads by the PMU. A full-wave rectifier using active diodes is used as the AC-DC converter for high efficiency, and a DC-DC boost converter architecture using a schottky diode is employed for a simple control circuitry. The proposed circuit has been designed in a 0.35um CMOS process, and the designed chip occupies $915{\mu}m{\times}895{\mu}m$. Simulation results shows that the maximum power efficiency of the entire system is 83.4%.