• Journal of Industrial Technology
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• v.26 no.B
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• pp.163-171
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• 2006

Human immunodeficiency virus type 1 (HIV-1) integrase plays a critical role in the life cycle of the HIV virus. An ability to accurately map its electrostatic potential, and then use this information to predict the manner in which DNA will bind to the active site of the catalytic domain could provide a foundation for inhibitory design. Attempts to discern the crystal structure of HIV-1 integrase have proven problematic, especially in the region of enzymatic activity, that being those residues involved in the catalysis of the integration of viral DNA into the host cell. However, there is a structural correlation in to the region of interest with avian sarcoma virus (ASV), so a homology model utilizing this similarity was constructed to approximate the behavior/structure of the undetermined portions of the HIV-1 integrase crystal. After this model was constructed and its energy minimized, electrostatic calculations were carried out on the substance, so that an electrostatic potential map was constructed. Using this information, it was determined that DNA binding was oriented so as to exploit the regions of positive potential nearby the active site, as well as the positive potential of the magnesium cofactors.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2005.05a
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• pp.662-667
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• 2005

Nonlinear dynamics of active piezolaminated plates are investigated with respect to the thermopiezoelastic behaviors. For largely deformed structures with small strain, the incremental total Lagrangian formulation is presented based on the virtual work principles. A multi field layer wise finite shell element is proposed for assuring high accuracy and non-linearity of displacement, electric and thermal fields. For dynamic consideration of thermopiezoelastic snap through phenomena, the implicit Newmark's scheme with the Newton-Raphson iteration is implemented for the transient response of various piezolaminated models with symmetric or eccentric active layers. The bifurcate thermal buckling of symmetric structural models is first investigated and the characteristics of piezoelectric active responses are studied for finding snap through piezoelectric potentials and the load path tracking map. The thermoelastic stable and unstable postbuckling, thermopiezoelastic snap through phenomena with several attractors are proved using the nonlinear time responses for various initial conditions and damping loss factors. Present results show that thermopiezoelastic snap through phenomena can result in the difficulty of buckling and postbuckling control of intelligent structures.

• Journal of Power Electronics
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• v.14 no.4
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• pp.778-787
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• 2014

This study presents an input filter resonance mitigation method for an AC-DC matrix converter. This method combines the advantages of the one-cycle control strategy and the active damping technique. Unnecessary sensors are removed, and system cost is reduced by employing the grid-side input currents as feedback to damp out LC resonance. A model that includes the proposed method and the input filter is established with consideration of the delay caused by the actual controller. A zero-pole map is employed to analyze model stability and to investigate virtual resistor parameter design principles. Based on a double closed-loop control scheme, the one-cycle control strategy does not require any complex modulation index control. Thus, this strategy can be more easily implemented than traditional space vector-based methods. Experimental results demonstrate the veracity of theoretical analysis and the feasibility of the proposed approach.

• 한국정보통신설비학회:학술대회논문집
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• 2008.08a
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• pp.181-185
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• 2008

Recently, location based service(LBS) expended based on personal specialized service, however since commercialized GPS based emergency rescue service comes with shadow zone for GPS signal such as inside building, the accuracy and reliability are not guaranteed. Therefore to improve such problem, we propose an active location detecting algorithm using RFID-TAG and Yagiantenna. To track the location of RFID-TAG where signal is generated, location tracking device in which Yagi-Antenna is installed moves around. Since directed wave and reflected wave co-exist during signal reception, final signal generated location is searched by setting up multiple of locations where signal can be generated on the map and moving location tracking device along minimum length of path. The algorithm proposed in this paper was verified of its technical validity through simulator.

• Journal of Sensor Science and Technology
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• v.10 no.1
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• pp.52-61
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• 2001

We propose a new saccadic eye movement system with visual selective attention. Saliency map models generate the scan pathways in a natural scene, of which the output makes an attended location. Saccadic eye movement model is used for producing the target trajectories to move the attended locations very rapidly. To categorize human saccadic eye movement, saccadic eye movement model was divided into three parts, each of which was then individually modeled using different neural networks to reflect a principal functionality of brain structures related with the saccadic eye movement in our brain. Based on the proposed saliency map models and the saccadic eye movement model, an active vision system using a CCD type camera and BLDC motor was developed and demonstrated with experimental results.

• Journal of Nutrition and Health
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• v.44 no.3
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• pp.196-202
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• 2011

Epigallocatechin gallate (EGCG), or epigallocatechin 3-gallate, is the ester of epigallocatechin and gallic acid, and is a type of catechin. EGCG may be therapeutic for many disorders including diabetics and some types of cancer. However it is unknown whether EGCG can induce transdifferentiation of pancreatic cells in pancreatitis. The aim of this study was to investigate the effects of EGCG on the expression of pancreatic regenerating related markers in pancreatic AR42J cells, a model of pancreatic progenitor cells. AR42J cells, differentiated with betacellulin and activin A, were cultured with/without EGCG in a time-dependent manner. Cell growth rate, levels of mRNA, and protein expression were examined with the MTT assay, quantitative PCR, and Western blots, respectively. The results showed that AR42J cell growth rates were inhibited by EGCG in a dose-dependent manner. mRNA and protein expression of amylase, insulin and neurogenin 3 (ngn 3) increased in AR42J cells treated with EGCG. Additionally, we demonstrated that the signal transduction pathway of mitogen-activated protein (MAP) kinase is active in EGCG-treated AR42J cells. ERK and JNK phosphorylation decreased in cells treated with EGCG but not p38 phosphorylation. Activation of the p38 MAP kinase pathway was confirmed by specific MAP kinase pathways inhibitors: U0126 for ERK, SP600126 for JNK, and SB203580 for p38. Activated p38 phosphorylation was inhibited by the specific p38 inhibitor SB203580 but p38 phosphorylation was inhibited with increased EGCG treatment. The ERK and JNK MAP kinase pathways were not affected by EGCG treatment. Although further studies are needed, these results suggest that EGCG affects the induction of pancreatic cell regeneration by increasing the ngn 3 protein and mRNA expression and activating the p38 MAP kinase pathway.

• Journal of the Korean association of regional geographers
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• v.4 no.2
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• pp.139-150
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• 1998

Recently in connection with the development of network technology, GIS researches shift their focuses to openGIS which enables to share heterogeneous geodata and geoprocessing resource under the environment of LAN and WAN. This study proposes an easy method to develope GUIs which enables openGIS in the intranet environment. In the developing stage of GUI, the most important thing is to develop effective windows programming technique and apply a internet linking technique to developed GUIs. This study shows an internet linking technique and a GUI developing method using OLE automation and ActiveX/COM standards. Using a case study of Taegu City Library, the study constructs a GIS database and develops its GUI which performs map overlaying, referencing attribute tables, drawing up of thematic map, buffer analysis, and statistical calculations. This study remains same further research areas of developing a new advanced technique for openGIS and its GUI using distributed object model of CORBA, Java language, and JDBC data accessing technique.

• 제어로봇시스템학회:학술대회논문집
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• 2004.08a
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• pp.312-316
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• 2004

The paper presents a technique to identify the boundary of the optic disc in infant retinal digital images using an approach based on active contours (snakes). The technique can be used to be develop a automate system in order to help the ophthalmologist's diagnosis the retinopathy of prematurity (ROP) disease which may occurred on preterm infant,. The optic disc detection is one of the fundamental step which could help to create an automate diagnose system for the doctors we use a new kind of active contour (snake) method has been developed by Chenyang et. al. [1], based on a new type of external force field, called gradient vector flow, or GVF. GVF is computed as a diffusion of the gradient vectors of a gray-level or binary edge map derived from the image. The testing results on a set of infant retinal ROP images verify the effectiveness of the proposed methods. We show that GVF has a large capture range and it's able to move snakes into boundary concavities of optic disc and finally the optic disk boundary was determined.

• Journal of Korean Society for Geospatial Information Science
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• v.3 no.2 s.6
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• pp.29-42
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• 1995

Route design in topographical plane map brings many problems in efficiency and requires much time and labor by hand Recently, the active studies of efficient route design method using 3-D terrain information are being developed according to increasing concentration on GSIS. In order to analyze terrain information for route design efficiently, this study presents objective and overall datum by applying SQL in construction and analysis of database and the possibility of three-dimensional terrain information analysis, This study generates 3-D base map on topographical map of scale 1:5,000 and acquires terrain information that have various thematic map data; contour, land use, roadway, and drange. This is a study on the application of SQL in route design and construction of the terrain information that linked by graphic datum of completed topographical map and attributed datum of database. As the result of this study, we can produce promptly and efficiently design datum of profile annotation, cross section, and volume computations to the preliminary route for route design and apply this efficient method to route design by understanding visual DTM which is composed of the roadway and the natural scene after design.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.12 no.2
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• pp.119-126
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• 2012

Recently, we used to recognize for human motions with some recognition algorithms. examples, HMM, DTW, PCA etc. In many human motions, we concentrated our research on recognizing fighting motions. In previous work, to obtain the fighting motion data, we used motion capture system which is developed with some active markers and infrared rays cameras and 3 dimension information converting algorithms by the stereo matching method. In this paper, we describe that the different method to acquiring 3 dimension fighting motion data and a HMM algorithm to recognize the data. One of the obtaining 3d data we used is depth map algorithm which is calculated by a stereo method. We test the 3d acquiring and the motion recognition system, and show the results of accuracy and performance results.