• 제목/요약/키워드: Activation Model

검색결과 1,777건 처리시간 0.023초

THERMALLY DRIVEN BUOYANCY WITHIN A HOT LAYER DUE TO SPRINKLER OPERATION

  • Nyankina, K.;F Turan, O.
    • Proceedings of the Korea Institute of Fire Science and Engineering Conference
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    • 한국화재소방학회 1997년도 International Symposium on Fire Science and Technology
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    • pp.625-632
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    • 1997
  • A two-dimensional zone-like model is developed to predict the interaction between hot gas layer and water droplets after sprinkler activation. The model combines the motion equations for each droplet with heat and mass transfer between the gas and water. The results indicate that negative buoyancy in the hot layer can only be obtained if the initial temperature profile is uniform. If an experimental profile Is used instead, positive buoyancy results. This conclusion has been confirmed with experimental data.

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Acupuncture Treatment at HT8 Supresses Seizure and Inflammation in Hippocampi on an Epilepsy Mice Model (간질(癎疾) 동물(動物) 모델을 이용한 소부혈(少府穴)의 간질발작(癎疾發作) 및 해마(海馬)의 염증(炎症) 억제 효과(效果) 검증(檢證))

  • Doo, Ah-Reum;Kim, Seung-Nam;Yin, Chang-Shik;Kim, Yeon-Jung;Lee, Hye-Jung;Kim, Seung-Tae;Park, Hi-Joon
    • Korean Journal of Acupuncture
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    • 제29권3호
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    • pp.396-405
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    • 2012
  • Objectives : To confirm whether acupuncture can suppress the degree of seizure and the activation of astrocytes in hippocampi using kainic acid(KA)-induced epilepsy mouse model. Methods : 8 weeks C57BL/6 mice(20~25 g) were given acupuncture once a day at acupoint HT8(Shaofu) bilaterally during 2 days before KA injection. After an intraperitoneal injection of 30 mg/kg KA, acupuncture treatment was subsequently administered once more(total 3 times), and the degree of seizure was observed for 120 min. The neuronal cell death, pERK expression, and astrocyte activation confirmed 1 hour and 24 hours after KA injection. Results : Acupuncture treatment at HT8 suppressed KA-induced epileptic seizure. One hour after KA injection, the pERK expression was increased, which was reduced by the acupuncture treatment. Twenty four hours after injection, the treatment decreased the KA-induced neuronal cell death, the interleukin-$1{\beta}$ expression and the astrocyte activation in the CA3 region of the mouse hippocampus. Conclusions : Acupuncture treatment at HT8 decreases the KA-induced epileptic seizure, the neural cell inflammation and death.

Study on the Thermal Decomposition Characteristics of the Tert-butylperoxymaleate using the DSC (DSC를 이용한 터셔리부틸퍼옥시말레이트의 열분해특성에 관한 연구)

  • Lee, Jung-Suk;Choi, Yi-Rac;Han, Ou-Sup
    • Journal of the Korean Institute of Gas
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    • 제24권3호
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    • pp.40-46
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    • 2020
  • Tertbutylperoxymaleate is the one of the organic peroxides used as a raw material of initiator formulations of artificial marble manufacturing. In this study, the thermal decomposition characteristic of TBPM was evaluated using the differential scanning calorimeter in the air and nitrogen circumstance. Regardless of the reaction atmosphere, TBPM showed the exothermic peak due to the drastic decomposition reaction below 130 ℃. The activation energy estimated by dynamic methods had a range of 203~217 kJ/mol and that estimated by model-free analysis method had a range of 118~232 kJ/mol with a thermal conversion. And the ADT24, the temperature that lead to the maximum heating rate within 24 hours, was evaluated as (80~95) ℃ using the estimated activation energy.

Acupuncture Stimulation at LI11 Suppresses Seizure and Apoptosis in Hippocampi on an Epilepsy Mouse Model (간질 동물 모델을 이용한 곡지(曲池) 및 족삼리(足三里)의 간질발작 및 해마 신경세포 보호 효과 비교 연구)

  • Lee, Jong Boon;Hwang, Kyoung Min;Yoo, Tae-Won;Bae, Chang-Hwan;Kwon, Sunoh;Kim, Seung-Tae
    • Korean Journal of Acupuncture
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    • 제30권1호
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    • pp.73-80
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    • 2013
  • Objectives : LI11 has been known to suppress epileptic seizure. Using an mouse epilepsy model, we investigated whether acupuncture stimulation at LI11 can suppress kainic acid(KA)-induced epileptic seizure and apoptosis in the mouse hippocampus. Methods : Eight-week-old male C57/BL6 mice(20~25 g) were given acupuncture at LI11 or ST36 once a day for 3 days. After the last acupuncture stimulations, KA(30 mg/kg) was injected intraperitoneally and the degree of seizure was observed for 90 minutes. Twenty-four hours after KA administration, mice were sacrificed and the neural cell death, astrocyte activation and caspase-3 expression in their hippocampi were investigated. Results : Acupuncture stimulation at LI11 suppressed KA-induced epileptic seizure, neuronal cell death, astrocyte activation and caspase-3 expression. Conclusions : Acupuncture stimulation at LI11 decreases the KA-induced epileptic seizure and protects hippocampal cell death via regulating astrocyte activation and caspase-3 expression.

Influence of Surrounding Gas and Coal Characteristics on Flame Propagation in Oxy-Fuel Combustion of Pulverized Coal (미분탄 순산소 연소에서 주위 기체와 석탄 특성이 화염전파에 미치는 영향)

  • Kang, Young-Min;Shim, Young-Sam;Moon, Cheor-Eon;Sung, Yon-Mo;Seo, Sang-Il;Kim, Tae-Hyung;Choi, Gyung-Min;Kim, Duck-Jool
    • Transactions of the Korean Society of Mechanical Engineers B
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    • 제33권1호
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    • pp.38-45
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    • 2009
  • Oxy-fuel combustion of pulverized coal is one of the promising new technologies to reduce $CO_2$ and NOx from coal combustion. However, the stability of pulverized coal flame is reduced in the oxy-fuel combustion. This flame stability is concerned with the flame propagation that is affected by surrounding gas and coal characteristics, such as gas temperature, gas composition, coal volatile, coal activation energy and coal size. In this paper, a study on the influence of surrounding gas and coal characteristics on the flame propagation velocity in oxy-fuel combustion of pulverized coal was preformed. One dimensional model was used to calculate the flame propagation velocity of pulverized coal clouds. In this model, the radiation is considered to be the main source of heat exchange, and Monte Carlo method was adopted for accurate calculation of radiation heat flux. It was found that the flame propagation velocity become higher with the decrease of coal activation energy and the increase of coal volatile. Also, according to the increase of gas temperature and $O_2$ concentration, flame propagation velocity increased.

Evaluation of refused tea waste activated carbon for color removal: Equilibrium and kinetic studies

  • Wijetunga, Somasiri;Gunasekara, Chathurika DFA
    • Advances in environmental research
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    • 제6권1호
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    • pp.1-14
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    • 2017
  • New technologies or improvement of the existing technologies are required to enhance the efficiency of removal of pollutants from wastewater. In this study we attempted to produce and test the activated carbon produced from the refused tea waste for the removal of dyes from wastewater. The objectives of this investigation were to produce activated carbon from refused tea waste by chemical activation, evaluate its performance for the removal of color produced from Acid Yellow 36, and the modeling of its dye removal with the kinetic study. The activation was performed in two steps namely carbonization at $375{\pm}25^{\circ}C$ and chemical activation with HCl at $800^{\circ}C$ under the absence of Oxygen. Adsorption isotherms and kinetic studies were performed with a textile dye, Acid Yellow 36, at different concentrations (20-80 mg/L). The maximum dye removal (~90%) observed at 80 mg/L dye concentration and it reduced at low dye concentrations. Maximum adsorption (71.97 mg/g) was recorded at 96 h at $29{\pm}1^{\circ}C$. Low pH increased the dye adsorption (pH=2; 78.27 mg/g) while adsorption reduced at high pH levels indicating that the competition occurs in between OH- ions and AY36 molecules for the adsorption sites in RTAC. The Langmuir isotherm model clearly explained the dye adsorption, favorably, by RTAC. Moreover, kinetic studied performed showed that the pseudo second order kinetic model clearly describes the dye adsorption. Based on the results obtained in this study, it can be concluded that RTAC can be used for the removal of textile dyes.

Hepatoprotective Effect of Uncaria rhynchophylla on Thioacetamide-Induced Liver Fibrosis Model

  • Choi, Jeong Won;Shin, Mi-Rae;Lee, Ji Hye;Roh, Seong-Soo
    • Biomedical Science Letters
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    • 제27권3호
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    • pp.142-153
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    • 2021
  • Liver fibrosis is a wound-healing response to chronic liver injury, which is caused by the continuous and excess deposition of extracellular matrix (ECM). The aim of this study is to investigate whether Uncaria rhynchophylla water extract (UR) can ameliorate thioacetamide (TAA)-induced liver fibrosis. The liver fibrosis model was induced on C57BL/6 mice by intraperitoneal injection with TAA three times a week for 8 weeks. UR (200 mg/kg) or silymarin (50 mg/kg) was administered orally daily for 8 weeks. Biochemical analyses including AST, ALT, MPO, and Ammonia levels were measured in serum. In the mice liver tissues, western blot and histological staining were analyzed. As a result, UR dramatically reduced the levels in serum AST, ALT, MPO, and Ammonia levels. UR treatment regulated NADPH oxidase factors expression, and antioxidant enzymes except for GPx-1/2 were significantly increased via Nrf2 activation. Furthermore, pro-inflammatory mediators, such as COX-2 and iNOS were markedly suppressed through the inhibition of NF-κB activation. Expressions of ECM-related protein including α-SMA and Collagen I were noticeably decreased. The additional histological evaluation confirmed that hepatocyte damage and collagenous fiber accumulation were attenuated. Taken together, these data suggest that UR possessed hepatoprotective effects in TAA-induced liver fibrosis via the NF-κB inactivation and Nrf2 activation. Therefore, UR may act as a potential therapeutic drug against liver fibrosis.

A Study on the Relationship between Cognitive Processes and Emotion Regulations in Depression and Anxiety Disorder: Focused on the Neurocognitive Networks (우울 및 불안 장애에서의 인지적 처리와 정서조절 고찰: 신경인지 연결망을 중심으로)

  • Kim, Choong-Myung
    • Journal of Industrial Convergence
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    • 제19권6호
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    • pp.177-186
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    • 2021
  • This review aims to propose a model that can reinterpret the abnormal and functional connections between cognitive processes and emotional regulations based on the neurocognitive networks for a comprehensive understanding of pathologic processes and treatment approach of depression and anxiety disorder. Through the processes of rebuilding the network model for depression and anxiety disorder, it was confirmed that depression can be said to be 'over-immersion in self-referencing' due to hyper-activation of default mode network (DMN), and anxiety disorders to be 'disconnection with self-referencing' due to hypo-activation of DMN. The attempts to link up between abnormal activation and pathological function of DMN which is thought to be involved in self-referential processing associated with self-consciousness and projection among neurocognitive networks may be another starting point that can afford to be suggestive in integrated interpretation and therapeutic approach to depression and anxiety disorder.