• Title/Summary/Keyword: Acquired resistance

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THREE-DIMENSIONAL FINITE ELEMENT ANALYSIS OF STRESS DISTRIBUTION AND PRELOAD OF DIFFERENT CONNECTION TYPES IMPLANT WITH INITIAL CLAMPING (임플랜트의 체결방식에 따른 초기조임력에 의한 응력분포 및 전하중에 관한 연구)

  • Lee Bum-Hyun;Chun Heoung-Jae;Lee Soo-Hong;Han Chong-Hyun
    • The Journal of Korean Academy of Prosthodontics
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    • v.44 no.2
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    • pp.197-206
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    • 2006
  • Statement of problem: One of common problems associated with single teeth dental implant prosthetic is the loosening of screws that retain the implants. Purpose: The maintenance of screw joint stability is considered a function of the preload achieved in the screw when the suggested initial tightening torque is applied. The purpose of this study was to investigate acquired preload after initial clamping torque for estimating screw joint stability. Material and methods: A comparative study on the effect of initial clamping of two types of implant systems with different connections was conducted Three dimensional non-linear finite element analysis is adopted to compare the characteristics of screw preloads and stress distributions between two different types of implant systems composed with abutment, screw, and fixture under the same loading and boundary conditions. Results: 1. When the initial clamping torque of 32Ncm was applied to the implant systems, all types of implants generated the maximum effective stress at the first helix region of screw. 2. Morse taper connection types of implants generate lower stress distributions compared to those by butt joint connection types or implants due to large contact surface between abutment and fixture. 3. The internal types of implant systems with friction grip type implant systems have higher resistance to screw loosening than that of the external types of implant systems since the internal types of implant systems generated larger preload than that generated by the external types for the same tightening moments.

A thermal properties of micro hot plate and the characteristics of Pt/Cr bilayers due to annealing temperature (미세 발열체의 발열특성과 열처리 온도에 따른 Pt/Cr 이중층의 특성)

  • Yi, Seung-Hwan;Suh, Im-Choon;Sung, Yong-Kwon
    • Journal of Sensor Science and Technology
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    • v.5 no.5
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    • pp.69-77
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    • 1996
  • In this paper, we fabricated the micro hotplate which consisted of a thin film heater(Pt/Cr bilayers) sandwiched with the thermal oxide and E-beam evaporated oxide. And we studied the electrical and the structural properties of Pt/Cr bilayers due to annealing temperature. When we compared the temperature measured from type k thermocouples with the temperature acquired from I.R. thermo-vision system according to the variations of emissivity, the emissivity of I-beam evaporated oxide was 0.5. The sheet resistance of Pt/Cr bilayers didn't depend on the Cr layer thickness, and it was considered as the existence of CrO between the Pt and the Cr layer. When the annealing temperature was increased from $500^{\circ}C$ to $700^{\circ}C$, the out-diffusions of Cr were increased(which was confirmed by AES depth profile) and the grain size of Pt(220) phase was enlarged also(analyzed by XRD and SEM photographs). From the results of XRD analysis and AES depth profile, the Pt/Cr bilayers annealed at $500^{\circ}C$ were more stable than any other cases in structural properties.

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A Review on the Performance Test of a High-Speed Planing Hull with 35 knot Speed by Appling the Streamlined Step of Hull Form (유선형 스텝 선형을 적용한 35 knot급 고속활주선의 성능평가에 대한 고찰)

  • Moon, Byung Young;Go, Ho Nam;Lee, Ki Yeol
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.30 no.3
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    • pp.95-102
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    • 2018
  • As a recent technical approach, a high-speed planing hull was tried to realize a friction reducing system by simultaneously actuating the triple streamlined step hull form in association with optimum speed of 35 knot planing for fishing boat. In this approach, the streamlined step hull form with triple structure of type was attached under the bottom of high-speed planing hull, while a friction resistance is reduced in the process of running at the speed of 35 knot. In addition, this research was to make a performance test as to the manufactured product and acquire the purposed values and the development items. Actually, after manufacturing the desired prototype of high-speed planing hull, the significant items, fuel efficiency (second) and amount of fuel consumption (degree) including maximum speed (knot) were estimated for a performance test. And tensile strength (MPa) and bend strength (MPa) as to the completed prototype like a high speed planing hull were also acquired during the test.

Mathematical Modeling and Simulation on the Control of Heart rate by Baroreceptor Control System in the Cardiovascular System (심혈관 시스템의 압수용체에 의한 심박동 제어의 수학적 모델링 및 시뮬레이션)

  • Choi, B.C.;Lee, S.J.;Eom, S.H.;Nam, G.K.;Lee, Y.W.;Jun, K.R.
    • Proceedings of the KOSOMBE Conference
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    • v.1996 no.11
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    • pp.80-85
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    • 1996
  • The various function of the cardiovascular system(CVS) and the dynamic characteristics on each part of human body can be acquired in the electric analog circuit model. According to the performed outcome by other researchers, viscos resistance, flow inertia, and vascular compliance in the CVS are analogous to resister, inductor, and capacitor in electric circuit, so the CVS models were represented by the electric circuit models. these approaches were to propose the suitable models interest part of body and to simulate the various characteristics on the CVS. In this paper, the electric circuit model considering the characteristics of morphologic structure is represented, the parameter values of model is sotted up, and the dynamic characteristics of the the CVS is simulated using VisSim, one of the simulation tools. The observed simulation results are similar to the cardiovascular functions of nomal adults who have no heart failure. Besides, the simulation is operated to observe the pathophysiological abnomal symptoms(for example, bleeding within a certain period). The controller by baroreceptor, which is one of controllers to control the CVS, is appended in the model. and the dynamic response characteristics and the procedure to return normal state is observed in simulation when the bleeding last within a certain period.

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Preliminary study on the quench protection of Bi-22231 Ag tape using superconducting fault current limiter (초전도 한류기를 이용한 Bi-2223/Ag 선재의 퀜치 보호를 위한 기초 연구)

  • Du, Ho-Ik;Yim, Seong-Woo;Hyun, Ok-Bae;Hwang, Si-Dole;Cho, Chul-Yong;Park, Chung-Ryul;Han, Byoung-Sung
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2006.06a
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    • pp.243-244
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    • 2006
  • As an preliminary study for the quench protection of high temperature superconducting (HTS) cable using superconducting fault current limiter (SFCL), experimental research was carried out. The test circuit was composed of Bi-2223/Ag HTS tape and a SFCL made of YBCO thin films. In the normal state, the applied current of 56 A, which was critical current of HTS tape, could be flown through the circuit without resistive loss. Increasing the currents, the quench development of both materials was investigated from the voltage signal acquired from the resistance of the quenched superconductor. Up to around 10 times of the critical current was applied to the HTS tape and the current limiting characteristics of SFCL were investigated. In addition, for the finding out the optimal operating condition of SFCL such as the numbers of elements, a shunt resistor was applied to the SFCL and quench characteristics were analyzed as well.

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Detection of Pathotypes and Genetic Diversity of Cercospora beticola

  • Turgay, Emine Burcu;Bakir, Melike;Ozeren, Pinar;Katircioglu, Yakup Zekai;Maden, Salih
    • The Plant Pathology Journal
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    • v.26 no.4
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    • pp.306-312
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    • 2010
  • The pathotypes of Cercospora beticola, causal agent of sugar beet leaf spot disease, were identified by application of pathogenicity test using 100 isolates obtained from the provinces with intensive sugar beet cultivation. For the identification of pathotypes, five sugar beet cultivars were used each with different resistance factors. Cultivar reactions were determined by inoculation of cultivars with the isolates under controlled conditions and measuring disease severity on the $15^{th}$ day according to the 1-9 KWS Scale. Based on the reactions of the five cultivars, a total of 15 pathotypes were detected. All employed sugar beet cultivars were resistant to Pathotype no:1 comprising most of the isolates. Genetic diversity of the causal agent was characterized by AFLP reaction. The products acquired at the end of AFLP reaction were detected by means of Beckman CEQ 8800 DNA Capillary Series Analysis and the results obtained were evaluated according to the similarity index UPGMA. For the genetic analysis of C. beticola isolates, 9874 polymorphic fragments of sizes between 100 and 500 bp were analysed which were generated by nine primers. The dendrogram derived from AFLP analysis depicted the existence of five different subgroups. The polymorphism rate among isolates was 91.13% and the dendrogram distribution of the pathotypes obtained by pathogenicity indicated that pathotypes were not discriminated and did not compose any groups.

Failure of Ciprofloxacin Therapy in the Treatment of Community-Acquired Acute Pyelonephritis caused by In-Vitro Susceptible Escherichia coli Strain Producing CTX-Type Extended-Spectrum β-Lactamase

  • Seok, Hyeri;Cha, Min Kyeong;Kang, Cheol-In;Cho, Sun Young;Kim, So Hyun;Ha, Young Eun;Chung, Doo Ryeon;Peck, Kyong Ran;Song, Jae-Hoon
    • Infection and chemotherapy
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    • v.50 no.4
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    • pp.357-361
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    • 2018
  • While carbapenems are the drug of choice to treat extended-spectrum-${\beta}$-lactamase (ESBL)-producing strains, some alternative carbapenem-sparing regimens are suggested for antibiotic stewardship. We experienced a case of ciprofloxacin treatment failure for acute pyelonephritis caused by an apparently susceptible Escherichia coli. A 71-year-old woman presented the emergency department with fever for 7 days and bilateral flank pain for 2 days. The laboratory results and abdominopelvic computed tomography finding were compatible with acute pyelonephritis. During 3-day ciprofloxacin therapy, the patient remained febrile with persistent bacteremia. After the change in antibiotics to ertapenem, the patient's clinical course started to improve. ESBL-producing E. coli isolates were identified in all three consecutive blood samples. Pulsed-field gel electrophoresis (PFGE) patterns, serotypes, and sequence types showed the three isolates were derived from the identical strain. The isolates produced CTX-M-14 type ESBL belonging to the ST69 clonal group. Despite in vitro susceptibility, the failure was attributed to a gyrA point mutation encoding Ser83Leu within quinolone resistance-determining regions. This case suggests that ciprofloxacin should be used cautiously in the treatment of serious infections caused by ciprofloxacin-susceptible, ESBL-producing E. coli, even in acute pyelonephritis because in-vitro susceptibility tests could fail to detect certain genetic mutations.

A Study on the Relationship with Thyroid Function and Stress using Heart Rate Variability (심박변이도를 이용한 갑상선 기능과 스트레스의 상관관계 연구)

  • Kim, Su-Min;Ye, Soo-Young
    • Journal of the Korean Society of Radiology
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    • v.16 no.5
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    • pp.545-551
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    • 2022
  • This study analyzed the correlation between stress measurements calculated through HRV signals and thyroid function test items. 181 healthy adults without disease who visited Clinic K were the subjects of this study. Stress resistance (SR) and stress index (SI) were calculated using the acquired HRV signal, and TSH, Free T4, and T3 were used as thyroid function test items. For the measured values, the relationship between each item was statistically analyzed through Pearson correlation analysis. From the results, it was confirmed that Free T4 and SR had a positive correlation (r=0.18) and a negative correlation with SI (r=-0.16). Through this, it was confirmed that there is a significant relationship between thyroid function and HRV signal.

ZNF204P is a stemness-associated oncogenic long non-coding RNA in hepatocellular carcinoma

  • Hwang, Ji-Hyun;Lee, Jungwoo;Choi, Won-Young;Kim, Min-Jung;Lee, Jiyeon;Chu, Khanh Hoang Bao;Kim, Lark Kyun;Kim, Young-Joon
    • BMB Reports
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    • v.55 no.6
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    • pp.281-286
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    • 2022
  • Hepatocellular carcinoma is a major health burden, and though various treatments through much research are available, difficulties in early diagnosis and drug resistance to chemotherapy-based treatments render several ineffective. Cancer stem cell model has been used to explain formation of heterogeneous cell population within tumor mass, which is one of the underlying causes of high recurrence rate and acquired chemoresistance, highlighting the importance of CSC identification and understanding the molecular mechanisms of CSC drivers. Extracellular CSC-markers such as CD133, CD90 and EpCAM have been used successfully in CSC isolation, but studies have indicated that increasingly complex combinations are required for accurate identification. Pseudogene-derived long non-coding RNAs are useful candidates as intracellular CSC markers - factors that regulate pluripotency and self-renewal - given their cancer-specific expression and versatile regulation across several levels. Here, we present the use of microarray data to identify stemness-associated factors in liver cancer, and selection of sole pseudogene-derived lncRNA ZNF204P for experimental validation. ZNF204P knockdown impairs cell proliferation and migration/invasion. As the cytosolic ZNF204P shares miRNA binding sites with OCT4 and SOX2, well-known drivers of pluripotency and self-renewal, we propose that ZNF204P promotes tumorigenesis through the miRNA-145-5p/OCT4, SOX2 axis.

South Korean State-Building, Nationalism and Christianity: A Case Study of Cold War International Conflict, National Partition and American Hegemony for the Post-Cold War Era

  • Benedict E. DeDominicis
    • International Journal of Advanced Culture Technology
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    • v.11 no.3
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    • pp.277-296
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    • 2023
  • The South Korean ethnic diaspora US lobby shows efficacy as an interest group in generating influence in American foreign and domestic public policy making. The persuasive portrayal of South Korea as a critical Cold War US ally reinforced US amenability to pro-South Korea lobbying. Also, the South Korean US diaspora is a comparatively recent immigrant group, thus its lingering resistance to assimilation facilitates its political mobilization to lobby the US government. One source of this influence includes the foundational legacy of proselytizing Western and particularly American religious social movement representatives in Korean religiosity and society. US protestant Christianity acquired a strong public association with emerging Korean nationalism in response to Japanese imperialism and occupation. Hostility towards Japanese colonialism followed by the threat from Soviet-sponsored, North Korean Communism meant Christianity did not readily become a cultural symbol of excessive external, US interference in South Korean society by South Korean public opinion. The post-Cold War shift in US foreign policy towards targeting so-called rogue state vestiges of the Cold War including North Korea enhanced further South Korea's influence in Washington. Due to essential differences in the perceived historical role of American influence, extrapolation of the South Korean development model is problematic. US hegemony in South Korea indicates that perceived alliance with national self-determination constitutes the core of soft power appeal. Civilizational appeal per se in the form of religious beliefs are not critically significant in promoting American polity influence in target polities in South Korea or, comparatively, in the Middle East. The United States is a perceived opponent of pan-Arab nationalism which has trended towards populist Islamic religious symbolism with the failure of secular nationalism. The pronounced component of evangelical Christianity in American core community nationalism which the Trump campaign exploited is a reflection of this orientation in the US.