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Comparison of porcine and human acellular dermal matrix outcomes in wound healing: a deep dive into the evidence

  • Saricilar, Erin Cihat;Huang, Sarah
    • Archives of Plastic Surgery
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    • v.48 no.4
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    • pp.433-439
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    • 2021
  • Acellular dermal matrices (ADM) are a novel graft. The goal of this systematic review is to evaluate the evidence behind differences in human and porcine ADM, irrelevant of manufacturing method, and to determine if there is enough of an evidence base to change clinical practice. An extensive literature search was performed through MEDLINE and Embase with search terms defining a population, intervention and outcome. Title and abstract exclusion were performed with other exclusion criteria. In 191 articles were found after exclusion of duplicates, with only 29 remaining following exclusions. Ten studies were found to have level I and II evidence (I=3, II=8), of which two were histopathological, one was an animal model, one was a systematic review, and six were clinical. The remaining studies were reviewed and considered for discussion, but did not hold high enough standards for medical evidence. Strong clinical evidence already exists for the use of human ADM, but questions of access, cost, and ethics require consideration of a xenograft. Histopathologically, evidence suggests minimal long-term differences between human and porcine ADM, although there is a short acute immune response with porcine ADM. Clinically, there is limited difference in outcomes, with a small range in effect of different ADM preparations. Considering the effectiveness of ADM in wound healing, more high-level research with appropriate statistical analysis to facilitate a future meta-analysis is recommended to justify a transition from human to porcine ADM.

Is IPO More Efficient Than Back-door-listing? : Case of Korean Kosdaq Market (IPO가 우회상장보다 정보효율성이 더 높은가? : 코스닥시장을 중심으로)

  • Kang, Won
    • The Korean Journal of Financial Management
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    • v.27 no.1
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    • pp.121-156
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    • 2010
  • Back-door-listing can be viewed both as M&A and an alternative to IPO. If IPO is an access to the capital market through regulations, back-door-listing would be the way of entering the market through trading. Back-door-listing can be a better choice considering the common wisdom that regulations hinder the functioning of free market system. One would, however, prefer IPO, for the informational asymmetry isless severe in case of IPO. This paper examines if IPO is superior to back-door-listing as to the informational efficiency. The excess buy-and-hold returns of the Kosdaq back-door-listing firms are estimated over the three-year-period since the event. They are compared against the excess buy-and-hold returns of the Kosdaq IPO firms over the same period of time. The results confirm this paper's prediction that IPO should be more information-efficient. Both IPO and back-door-listing firms start with high short-term excess returns and end up with long-term under-performance. However, back-door-listing firms show more significantly damaging long-term results. Furthermore, back-door-listing firms record poorer accounting results over the research period. These results imply that there exists fad at the time of both events and, in case of back-door-listing, this fad is reinforced by the possibility of window dressing.

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A Study on the role of buyers and sellers in e-Marketplace (e-Marketplace에서의 구매자와 판매자의 역할분석)

  • 조원길
    • The Journal of Information Technology
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    • v.5 no.1
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    • pp.157-171
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    • 2002
  • The evolution of transaction-based business model is upon us. The business models of many e-Marketplace in their early stages have typically been based on transaction fees. Many e-Marketplaces have even called out transaction revenues as a core element of their business plans. The transaction business represents the most simple of business models, but it does not provide a long-term sustain able advantage. For buyer's convenience, wide selection and test price hold appeal. For suppliers, the extended global market reach and direct access to customers and consortiums of customers is powerful. To maxmize leverage of these new e-marketplace, you must from both a buyer perspective as well as a supplier perspective. Also required is a strategy that takes in account all of the various e-Marketplace transaction standards and one that allows the easy accomodation to new e-marketplace as the market change. These new e-marketplace will need to be factored into the sales channel strategies. To be successful, integration with these e-marketplaces should occur at a complete business process level. This study explored independent and industry-backed current and future business models that are emerging in the B2B electronic market industry, as well as value -added service models for the Net market maker industry. E-Marketplaces will evolve into digital work environments in which real industry collaboration can occur.

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An Analysis the Role between the Buyer and Seller in the Field of e-Trade (전자무역에서 구매자와 판매자의 역할분석)

  • Lee, Joo-Won
    • International Commerce and Information Review
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    • v.7 no.3
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    • pp.195-212
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    • 2005
  • International trade has been changed from traditional trade to e-trade due to the fast expanding of information technology like e-marketplace, EDI (Electronic data interchange) using Internet since mid of 1990's. e-Trade, as a new trade method, could handle every trade procedure such as market research, contract, customs clearance, logistics and payment using IT like internet without restriction of time and space. The evolution of transaction-based business model is upon us. The business models of many e-Marketplace in their early stages have typically been based on transaction fees. Many e-Marketplaces have even called out transaction revenues as a core element of their business plans. The transaction business represents the most simple of business models, but it does not provide a long-term sustain able advantage. For buyer's convenience, wide selection and test price hold appeal. For suppliers, the extended global market reach and direct access to customers and consortiums of customers is powerful. To maximize leverage of these new e-marketplace, you must from both a buyer perspective as well as a supplier perspective. Also required is a strategy that takes in account all of the various e-Marketplace transaction standards and one that allows the easy accomodation to new e-marketplace as the market change. These new e-marketplace will need to be factored into the sales channel strategies. To be successful, integration with these e-marketplaces should occur at a complete business process level. This study would suggest on the role of buyers and sellers for e-trade which could maximize effect of e-trade in order to cope with rapid changing IT environment and global trade environment. Therefore, this study suggests top priority tasks for implementing on the specialization strategy of e-trade process.

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Performance Analyses of Instruction Fetch Models Considering Cache Miss and Branch Misprediction (캐쉬 미스와 분기예측 실패를 고려한 명령어 페치 모델의 성능분석)

  • Kim, Seon-Mo;Jeong, Jin-Ha;Choe, Sang-Bang
    • Journal of KIISE:Computer Systems and Theory
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    • v.28 no.12
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    • pp.685-697
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    • 2001
  • Cache memories are small fast memories used to temporarily hold the contents of main memory that are likely to be referenced by processors so as to reduce instruction and data access time. In this paper, we represent analytical models of instruction fetch process for four types of instruction cache structures that can be used for superscalar processors. In the models, we define various kinds of architectural parameters and take cache miss and branch misprediction into consideration. To prove the correctness of the proposed models, we performed extensive simulations and compared the results with the analytical models. Simulation results showed that the proposed model can estimate the instruction fetch rate accurately within 10% error in most cases. Both analytical model and simulation show that the increase of cache misses reduces the instruction fetch rate more severely than that of branch misprediction does. However, the analytical model can explain the causes of performance degradation which cannot be uncovered by the simulation method only. The model is also able to provide exact relationship between cache miss and branch misprediction for instruction fetch analysis.

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A Study on the Classification of Types of Han Riverside Forests -In the Case of Yangpyeng and Yeoju gun- (남한강변 강변숲 조성을 위한 유형분류연구 -경기도 양평·여주군 구간을 중심으로-)

  • Jang, Dong-Su
    • KIEAE Journal
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    • v.10 no.1
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    • pp.3-10
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    • 2010
  • Riverside forests make a river bank stable because trees of them hold together the stone and soil by roots and decrease the speed of running fluid by trunks. So they become known to have positive effects on flood prevention. So This study will be a basic study to preserve and restore of riverside forests. The goal of this study is to classify types of Han riverside forests between Yangpyeng and Yeoju gun. and find out sites of planting. Results of this study can be summarized as follows; The evaluation indicators were set up based on literature review and site survey. Two indicator categories were developed: natural environment and human environment. And they were divided into 5 sub-categories for calculating weights. As for the major indicator categories, the weighted index of natural environment is at 0.5. And the weighted index of human environment is at 0.5 followed by access at 0.15, the range of user at 0.15, cultivated land at 0.1 and legislation at 0.1. This study selected 53 sites for riverside forests planting. They were classified with types of bank(11), level-upped riverside(32), island(10). The amount of the length of 11 bank types is 23,050m, the area of 32 level-upped riverside types is $4,490,000m^2$ and the area of 10 island types is $4,590,000m^2$. After the evaluation of 53 riverside forests, this study selected 12 sites of riverside forests. They were two bank types, nine level-upped riverside types, and one island type. Rebuilding riverside forests are to accomplish the green network which links and divides region. It will be one of the best ecological methods to construct friendly environmental region.

A Study on Economic Cooperation between Korea and Pacific Alliance (태평양동맹(Pacific Alliance)과 한국의 경제협력에 관한 연구)

  • Park, Chong-Suk
    • Asia-Pacific Journal of Business
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    • v.11 no.4
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    • pp.303-315
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    • 2020
  • Purpose - The purpose of this study is to analyze Korea's trade relations centered on the Pacific Alliance (PA), a major economic integration in Latin America, and identify its problems and suggest measures that can be taken by the government and corporations to reinforce economic cooperation. Design/methodology/approach - To improve the level of contribution of the study, an empirical analysis is necessary. However, due to limited data access, the study will approach the topic of trade relations between Korea and the PA with various statistics and literature. Findings - First, there is an urgent need for changes in import-export goods between Korea and the PA, as trade is focused on specific items. Second, although foreign direct investment from Korea to the PA is centered in manufacturing and mining industries, there should be different investment strategies by countries and industries. Third, it is necessary to reinforce commercial cooperation. Korea currently has Free Trade Agreements with Chile, Peru, and Columbia, but not with Mexico, the largest trading partner among the PA. Therefore, Korea must take active measures to sign an FTA with Mexico, which has been put on hold. Research implications or Originality - Latin America has the most thriving market when it comes to Free Trade Agreements worldwide. With the official establishment of the Pacific Alliance (PA) in 2012, the economic integration of Latin America faced entirely new circumstances. Reinforcing economic cooperation with the PA is extremely important for Korea in terms of entering and dominating the Latin American market. However, there is still a lack of research on the Pacific Alliance, and corporations that aim to enter the Latin American market face difficulties due to lack of information. By investigating the Pacific Alliance and its prospects and analyzing the trade relations with Korea, this study will provide strategic measures for corporations that wish to enter the Latin American market.

Generic Costing Scheme Using General Equilibrium Theory for Fair Cloud Service Charging

  • Hussin, Masnida;Jalal, Siti Fajar;Latip, Rohaya
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.15 no.1
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    • pp.58-73
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    • 2021
  • Cloud Service Providers (CSPs) enable their users to access Cloud computing and storage services from anywhere in quick and flexible manners through the Internet. With the basis of 'pay-as-you-go' model, it makes the interactions between CSPs and the users play a vital role in shaping the Cloud computing market. A pool of virtualized and dynamically scalable Cloud services that delivered on demand to the users is associated with guaranteed performance and cost-provisioning. It needed a costing scheme for determining suitable charges in order to secure lease pricing of the Cloud services. However, it is hard to meet the satisfied prices for both CSPs and users due to their conflicting needs. Furthermore, there is lack of Service Level Agreements (SLAs) that allowing the users to take part into price negotiating process. The users may lose their interest to use Cloud services while reducing CSPs profit. Therefore, this paper proposes a generic costing scheme for Cloud services using General Equilibrium Theory (GET). GET helps to formulate the price function for various services' factors to match with various demands from the users. It is initially determined by identifying the market circumstances that a general equilibrium will be hold and reached. Specifically, there are two procedures of agreement made in response to (i) established equilibrium supply and demand, and (ii) service price formed and constructed in a price range. The SLAs in our costing scheme is integrated to satisfy both CSPs and users' needs while minimizing their conflicts. The price ranging strategy is deliberated to provide prices' options to the users with respect their budget limit. Meanwhile, the CSPs can adaptively charge based on users' preferences without losing their profit. The costing scheme is testable and analyzed in multi-tenant computing environments. The results from our simulation experiments demonstrate that the proposed costing scheme provides better users' satisfaction while fostering fairness pricing in the Cloud market.

Comparison of Home Automation System Using IPV-4 and IPV-6 Based On Mitigate Reconnaissance Attacks

  • Ali, Muhammad Shujat;Siddiq, Imran;Faisal, Abdullah;Awan, Muhammad Zubair
    • International Journal of Computer Science & Network Security
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    • v.22 no.2
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    • pp.341-347
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    • 2022
  • This research is designed to help and offer hold up to complete the requirements of aged and disable in a home. The control approach and the tone approach are used to manage the house appliances. The major organize system implementation in technology of wireless to offer distant contact from a phone Internet Protocol connectivity for access and calculating strategy and appliance remotely. The planned system no need a committed server PC with value of parallel systems and offers a new communication-protocol to observe and control a house environment with more than just the switch functionality. To express the possibility and efficiency of this system, devices like as lights switches, power plugs, and motion-sensors have been included with the planned home control system and supply more security manage on the control with low electrical energy activate method. The rank of switches is corresponding in all this control system whereby all user interfaces indicate the real time existing status. This system planned to manage electrical-appliances and devices in house with reasonably low cost of design, user friendly interface, easily install and provide high security. Research community generally specified that the network "Reconnaissance Attacks" in IPv6 are usually impossible due to they will take huge challenge to carry out address scanning of 264 hosts in an IPv6 subnet."It being deployed of IPv6 shows that it definitely enhances security and undermines the probability". This research of the IPv6 addressing-strategies at present utilizes and planned a new strategy and move toward to "mitigate reconnaissance attacks".

A Comparative Study on the Service Characteristics for Transferring Process of High-Speed Rail and Domestic Airline Systems by Using Structural Equation Modeling (공분산구조분석을 이용한 고속철도와 국내항공의 이동단계별 서비스특성 비교연구)

  • Kim, Tae Ho;Jeong, Kwang Seop;Park, Je Jin
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.29 no.2D
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    • pp.183-190
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    • 2009
  • In order to improve continuous success and stabilization of high-speed rail in the future, Using Frequency of high-speed rail should be enhanced by improving satisfaction of high-speed rail passenger. High-speed rail is needed to hold the priority in competition means by comparing the traits of service of domestic air lines. This study utilizes structural equation modeling to develop model for estimating factors influencing to service through conducting survey questionnaire. It also uses reliability analysis, correlation analysis, factor analysis to examine the rationalization of items and to establish hypothesis of this research. The results show that KTX contains 'inner service' item that is considered to be ameliorated and that domestic airline present low performance of 'outer service' item. In other words, moving section which partly is under a limited condition is needed to be improved. In addition, access to airport and transfer to other transportations have to be improved as they show the lowest satisfaction.