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Comparison of porcine and human acellular dermal matrix outcomes in wound healing: a deep dive into the evidence

  • Saricilar, Erin Cihat;Huang, Sarah
    • Archives of Plastic Surgery
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    • 제48권4호
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    • pp.433-439
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    • 2021
  • Acellular dermal matrices (ADM) are a novel graft. The goal of this systematic review is to evaluate the evidence behind differences in human and porcine ADM, irrelevant of manufacturing method, and to determine if there is enough of an evidence base to change clinical practice. An extensive literature search was performed through MEDLINE and Embase with search terms defining a population, intervention and outcome. Title and abstract exclusion were performed with other exclusion criteria. In 191 articles were found after exclusion of duplicates, with only 29 remaining following exclusions. Ten studies were found to have level I and II evidence (I=3, II=8), of which two were histopathological, one was an animal model, one was a systematic review, and six were clinical. The remaining studies were reviewed and considered for discussion, but did not hold high enough standards for medical evidence. Strong clinical evidence already exists for the use of human ADM, but questions of access, cost, and ethics require consideration of a xenograft. Histopathologically, evidence suggests minimal long-term differences between human and porcine ADM, although there is a short acute immune response with porcine ADM. Clinically, there is limited difference in outcomes, with a small range in effect of different ADM preparations. Considering the effectiveness of ADM in wound healing, more high-level research with appropriate statistical analysis to facilitate a future meta-analysis is recommended to justify a transition from human to porcine ADM.

IPO가 우회상장보다 정보효율성이 더 높은가? : 코스닥시장을 중심으로 (Is IPO More Efficient Than Back-door-listing? : Case of Korean Kosdaq Market)

  • 강원
    • 재무관리연구
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    • 제27권1호
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    • pp.121-156
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    • 2010
  • 본 연구에서는 2003년~2005년 기간에 코스닥 시장에서 발생한 두 가지 자본시장 진입수단인 IPO와 우회상장을 대상으로 벤치마킹 대비 단기 및 장기 초과보유수익률을 분석하고, 차이점과 의미에 대해 논하였다. 우회상장은 M&A의 성격을 띠고 있지만 동시에 IPO의 성격도 갖고 있다. IPO는 거래소가 제시한 상장요건을 맞춰야 하는 등 제도적인 간섭을 받기 때문에 제도에 의한 자본시장 진입방법이라고 할 수 있다. 반면 우회상장은 이러한 제도의 간섭은 미미하고 당사자 간의 거래에 의하여 진입여부가 결정되기 때문에 거래에 의한 자본시장 진입방법이라고 할 수 있다. 제도가 완전시장을 저해한다는 상식에 기초한다면우회상장이 IPO보다 우수한 진입방법이라고 판단할 수 있지만, 반대로 IPO는 우회상장에 비해 정보의 비대칭성을 줄이고 부실한 기업의 시장진입을 통제할 수 있다는 면에서 장점이 있다고 볼 수 있다. 본 연구의 결과는 정보의 효율성 면에서 IPO가 우수하다는 본문의 주장을 지지하고 있다. 먼저 IPO 기업과 우회상장 기업은 모두 초기에는 높은 초과수익률을 기록하고 장기적으로는 둘 다 저성과를 보이나 우회상장 기업의 장기성과가 더욱 하락하였다. 또한 두 표본 모두 사건 이후 3년 간의 회계적 성과가 하락하였으나 특히 우회상장 기업은 더욱 하락하였으며 모든 기간에서 손실을 기록하였다. 이는 과잉수요(fad)가 코스닥 시장의 IPO는 물론 우회상장에서도 똑같이 존재하며, 우회상장의 경우에는 과대포장(window dressing)의 가능성이 더욱 높음을 뜻한다. 결국 IPO보다는 우회상장이 상장시점에서 회사와 투자자 사이에 더욱 심한 정보의 비대칭성을 보이고 있음을 시사한다.

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e-Marketplace에서의 구매자와 판매자의 역할분석 (A Study on the role of buyers and sellers in e-Marketplace)

  • 조원길
    • 정보학연구
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    • 제5권1호
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    • pp.157-171
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    • 2002
  • e-Marketplace는 B2B 거래의 한 종류로서 인터넷상에서 불특정 다수의 공급자와 수요자(N:N)간 비즈니스 거래를 유발시켜 주는 가상의 시장인데 전세계적으로 특정 산업에 한정된 수직적인 e-Marketplace와 특정 산업과 관계없는 수평적인 e-Marketplace형태로 발전되고 있다. e-marketplace는 구매자와 판매자에게 제공하는 이점들 때문에 놀라운 속도로 증가하고 있다. 구매자입장에 e-marketplace는 새로운 공급업체를 물색하는 과정에서 들어가는 구매비용을 낮출 수 있다. 공급업체의 경우 e-Marketplace는 판매비용을 낮추고 새로운 고객에게 물품을 납품할 수 있는 기회를 제공한다. 이에 e-marketplace 기업들도 분명한 비즈니스모델로서 경쟁력 있는 업체만이 생존할 것이다. 이러한 생존에서 살아남기 위해서는 치열한 경쟁을 이겨내야 한다. 이에 대한 구매자와 판매자의 역할이 무엇인지를 살펴 보는 것이 본 연구의 목적이다.

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전자무역에서 구매자와 판매자의 역할분석 (An Analysis the Role between the Buyer and Seller in the Field of e-Trade)

  • 이주원
    • 통상정보연구
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    • 제7권3호
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    • pp.195-212
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    • 2005
  • International trade has been changed from traditional trade to e-trade due to the fast expanding of information technology like e-marketplace, EDI (Electronic data interchange) using Internet since mid of 1990's. e-Trade, as a new trade method, could handle every trade procedure such as market research, contract, customs clearance, logistics and payment using IT like internet without restriction of time and space. The evolution of transaction-based business model is upon us. The business models of many e-Marketplace in their early stages have typically been based on transaction fees. Many e-Marketplaces have even called out transaction revenues as a core element of their business plans. The transaction business represents the most simple of business models, but it does not provide a long-term sustain able advantage. For buyer's convenience, wide selection and test price hold appeal. For suppliers, the extended global market reach and direct access to customers and consortiums of customers is powerful. To maximize leverage of these new e-marketplace, you must from both a buyer perspective as well as a supplier perspective. Also required is a strategy that takes in account all of the various e-Marketplace transaction standards and one that allows the easy accomodation to new e-marketplace as the market change. These new e-marketplace will need to be factored into the sales channel strategies. To be successful, integration with these e-marketplaces should occur at a complete business process level. This study would suggest on the role of buyers and sellers for e-trade which could maximize effect of e-trade in order to cope with rapid changing IT environment and global trade environment. Therefore, this study suggests top priority tasks for implementing on the specialization strategy of e-trade process.

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캐쉬 미스와 분기예측 실패를 고려한 명령어 페치 모델의 성능분석 (Performance Analyses of Instruction Fetch Models Considering Cache Miss and Branch Misprediction)

  • 김선모;정진하;최상방
    • 한국정보과학회논문지:시스템및이론
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    • 제28권12호
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    • pp.685-697
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    • 2001
  • 캐쉬 메모리는 명령어와 데이터의 참조시간을 줄이기 위하여 프로세서에 의해 참조되어질 가능성이 높은 주 메모리의 내용을 일시적으로 저장하는 용량이 작고 빠른 메모리이다. 본 논문에서는 슈퍼스칼라 프로세서에 적용될 수 있는 네 가지 명령어 캐쉬 구조에 대하여 캐쉬 미스와 분기예측 실패를 고려한 해석적 모델을 제안하고 성능을 분석하였다. 슈퍼스칼라 구조의 다양한 파라미터들을 정의하여 명령어 페치를 모델링하였으며, 해석적 모델의 타당성을 검증하기 위하여 시뮬레이션을 수행하여 얻은 결과와 비교하였다. 명령어 페치율에 있어서는 분기예측 실패로 인한 영향보다는 캐쉬 미스로 인한 성능저하가 더욱 큰 것으로 나타났다. 본 연구를 통하여 얻은 해석적 모델을 사용하면 시뮬레이션에서는 드러나지 않는 성능제약의 원인에 대한 명확한 규명이 가능하며, 캐쉬 성능에 있어서 캐쉬 미스와 분기예측 실패간의 관계에 대한 정확한 분석이 가능하다.

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남한강변 강변숲 조성을 위한 유형분류연구 -경기도 양평·여주군 구간을 중심으로- (A Study on the Classification of Types of Han Riverside Forests -In the Case of Yangpyeng and Yeoju gun-)

  • 장동수
    • KIEAE Journal
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    • 제10권1호
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    • pp.3-10
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    • 2010
  • Riverside forests make a river bank stable because trees of them hold together the stone and soil by roots and decrease the speed of running fluid by trunks. So they become known to have positive effects on flood prevention. So This study will be a basic study to preserve and restore of riverside forests. The goal of this study is to classify types of Han riverside forests between Yangpyeng and Yeoju gun. and find out sites of planting. Results of this study can be summarized as follows; The evaluation indicators were set up based on literature review and site survey. Two indicator categories were developed: natural environment and human environment. And they were divided into 5 sub-categories for calculating weights. As for the major indicator categories, the weighted index of natural environment is at 0.5. And the weighted index of human environment is at 0.5 followed by access at 0.15, the range of user at 0.15, cultivated land at 0.1 and legislation at 0.1. This study selected 53 sites for riverside forests planting. They were classified with types of bank(11), level-upped riverside(32), island(10). The amount of the length of 11 bank types is 23,050m, the area of 32 level-upped riverside types is $4,490,000m^2$ and the area of 10 island types is $4,590,000m^2$. After the evaluation of 53 riverside forests, this study selected 12 sites of riverside forests. They were two bank types, nine level-upped riverside types, and one island type. Rebuilding riverside forests are to accomplish the green network which links and divides region. It will be one of the best ecological methods to construct friendly environmental region.

태평양동맹(Pacific Alliance)과 한국의 경제협력에 관한 연구 (A Study on Economic Cooperation between Korea and Pacific Alliance)

  • 박종석
    • 아태비즈니스연구
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    • 제11권4호
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    • pp.303-315
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    • 2020
  • Purpose - The purpose of this study is to analyze Korea's trade relations centered on the Pacific Alliance (PA), a major economic integration in Latin America, and identify its problems and suggest measures that can be taken by the government and corporations to reinforce economic cooperation. Design/methodology/approach - To improve the level of contribution of the study, an empirical analysis is necessary. However, due to limited data access, the study will approach the topic of trade relations between Korea and the PA with various statistics and literature. Findings - First, there is an urgent need for changes in import-export goods between Korea and the PA, as trade is focused on specific items. Second, although foreign direct investment from Korea to the PA is centered in manufacturing and mining industries, there should be different investment strategies by countries and industries. Third, it is necessary to reinforce commercial cooperation. Korea currently has Free Trade Agreements with Chile, Peru, and Columbia, but not with Mexico, the largest trading partner among the PA. Therefore, Korea must take active measures to sign an FTA with Mexico, which has been put on hold. Research implications or Originality - Latin America has the most thriving market when it comes to Free Trade Agreements worldwide. With the official establishment of the Pacific Alliance (PA) in 2012, the economic integration of Latin America faced entirely new circumstances. Reinforcing economic cooperation with the PA is extremely important for Korea in terms of entering and dominating the Latin American market. However, there is still a lack of research on the Pacific Alliance, and corporations that aim to enter the Latin American market face difficulties due to lack of information. By investigating the Pacific Alliance and its prospects and analyzing the trade relations with Korea, this study will provide strategic measures for corporations that wish to enter the Latin American market.

Generic Costing Scheme Using General Equilibrium Theory for Fair Cloud Service Charging

  • Hussin, Masnida;Jalal, Siti Fajar;Latip, Rohaya
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제15권1호
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    • pp.58-73
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    • 2021
  • Cloud Service Providers (CSPs) enable their users to access Cloud computing and storage services from anywhere in quick and flexible manners through the Internet. With the basis of 'pay-as-you-go' model, it makes the interactions between CSPs and the users play a vital role in shaping the Cloud computing market. A pool of virtualized and dynamically scalable Cloud services that delivered on demand to the users is associated with guaranteed performance and cost-provisioning. It needed a costing scheme for determining suitable charges in order to secure lease pricing of the Cloud services. However, it is hard to meet the satisfied prices for both CSPs and users due to their conflicting needs. Furthermore, there is lack of Service Level Agreements (SLAs) that allowing the users to take part into price negotiating process. The users may lose their interest to use Cloud services while reducing CSPs profit. Therefore, this paper proposes a generic costing scheme for Cloud services using General Equilibrium Theory (GET). GET helps to formulate the price function for various services' factors to match with various demands from the users. It is initially determined by identifying the market circumstances that a general equilibrium will be hold and reached. Specifically, there are two procedures of agreement made in response to (i) established equilibrium supply and demand, and (ii) service price formed and constructed in a price range. The SLAs in our costing scheme is integrated to satisfy both CSPs and users' needs while minimizing their conflicts. The price ranging strategy is deliberated to provide prices' options to the users with respect their budget limit. Meanwhile, the CSPs can adaptively charge based on users' preferences without losing their profit. The costing scheme is testable and analyzed in multi-tenant computing environments. The results from our simulation experiments demonstrate that the proposed costing scheme provides better users' satisfaction while fostering fairness pricing in the Cloud market.

Comparison of Home Automation System Using IPV-4 and IPV-6 Based On Mitigate Reconnaissance Attacks

  • Ali, Muhammad Shujat;Siddiq, Imran;Faisal, Abdullah;Awan, Muhammad Zubair
    • International Journal of Computer Science & Network Security
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    • 제22권2호
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    • pp.341-347
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    • 2022
  • This research is designed to help and offer hold up to complete the requirements of aged and disable in a home. The control approach and the tone approach are used to manage the house appliances. The major organize system implementation in technology of wireless to offer distant contact from a phone Internet Protocol connectivity for access and calculating strategy and appliance remotely. The planned system no need a committed server PC with value of parallel systems and offers a new communication-protocol to observe and control a house environment with more than just the switch functionality. To express the possibility and efficiency of this system, devices like as lights switches, power plugs, and motion-sensors have been included with the planned home control system and supply more security manage on the control with low electrical energy activate method. The rank of switches is corresponding in all this control system whereby all user interfaces indicate the real time existing status. This system planned to manage electrical-appliances and devices in house with reasonably low cost of design, user friendly interface, easily install and provide high security. Research community generally specified that the network "Reconnaissance Attacks" in IPv6 are usually impossible due to they will take huge challenge to carry out address scanning of 264 hosts in an IPv6 subnet."It being deployed of IPv6 shows that it definitely enhances security and undermines the probability". This research of the IPv6 addressing-strategies at present utilizes and planned a new strategy and move toward to "mitigate reconnaissance attacks".

공분산구조분석을 이용한 고속철도와 국내항공의 이동단계별 서비스특성 비교연구 (A Comparative Study on the Service Characteristics for Transferring Process of High-Speed Rail and Domestic Airline Systems by Using Structural Equation Modeling)

  • 김태호;정광섭;박제진
    • 대한토목학회논문집
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    • 제29권2D호
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    • pp.183-190
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    • 2009
  • 고속철도가 향후 지속적인 성과와 안정화를 도모하기 위해서는 고속철도 이용승객의 만족도를 높여 주어 지속적으로 고속철도를 이용하도록 해야 한다. 동시에 고속철도와 경쟁수단이라 할 수 있는 국내항공을 이용하는 고객과의 서비스특성 비교를 통하여 경쟁수단으로부터 우위를 점해야 한다. 구조방정식을 이용한 이용자의 서비스영향 모형개발을 위해 설문조사를 실시하였으며, 신뢰성분석, 상관분석, 요인분석을 통해 측정지표의 타당성 및 연구가설 설정을 위한 기초분석을 수행하였다. 구조방정식모형을 이용하여 경쟁수단간 서비스특성을 분석한 결과, 고속철도(KTX)는 이용자의 내부서비스(대기, 이동)를 개선해야 하는 것으로 나타났으며, 국내항공은 이용자의 외부서비스(접근, 환승)를 개선해야 하는 것으로 나타났다. 다시 말하면, 고속철도(KTX)의 경우 대기시설과 현재 일부구간에 제약을 받고 있는 이동부분에 개선이 필요한 것을 알 수 있으며, 국내 항공의 경우 공항으로의 접근 및 타 교통수단으로의 환승은 불편한 것으로 나타나 국내항공 이용시 접근체계 및 환승에 대 한 서비스 개선이 필요한 것으로 판단된다.