• Title/Summary/Keyword: Acceptable risk

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Evaluation of Korean Version of the Beliefs about Papanicolau Test and Cervical Cancer in Unmarried University Students (한국판 자궁경부암과 Pap 검사 신념 도구의 타당도 신뢰도 평가: 미혼 여대생 대상)

  • Kim, Hae Won;Ko, Ga Yeon
    • Women's Health Nursing
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    • v.19 no.1
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    • pp.13-22
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    • 2013
  • Purpose: This study was conducted to evaluate Korean version of the beliefs about Papanicolau (Pap) test and cervical cancer [CPC-28] in unmarried university students. Methods: The Korean version of CPC-28 (K-CPC-28) was developed through forward-backward translation techniques. A reliability, confirmatory factor analysis and correlations coefficients were evaluated. Data were collected from 303 unmarried female students attending university using a questionnaire that included28 items of CPC, 5 items of susceptibility of cervicalcancer and 8 items of HPV knowledge. Results: K-CPC-28 had reliable internal consistency with Cronbach's ${\alpha}$=.74 of six subscales ranged from .66 to .80. Factor loadings of the 28 items of subscales ranged from .31 to .86. Six factors in this study explained 55% of the total variance. In convergent validity of the K-CPC-28, the subscales of K-CPC-28 were significantly correlated with susceptibility scale of cervical cancer and HPV knowledge scale. Conclusion: K-CPC-28has satisfactory construct validity and reliability. It seems to be an acceptable tool to assess the attitudes toward cervical cancer prevention and Pap smear in unmarried women. This tool would be also applicable to screen the risk group in cervical cancer prevention and to identify its association with actual Pap test or cervical cancer prevention behaviors.

Investigation and Evaluation on Performance of Durability for Freeway Concrete Viaducts in Seoul Metropolitan Area (서울시내 위치한 콘크리트 고가차도의 내구성능 조사 및 평가)

  • Lee, Chang-Soo;Yoon, In-Seok
    • Journal of the Korean Society of Hazard Mitigation
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    • v.2 no.1 s.4
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    • pp.143-152
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    • 2002
  • The objectives of this paper were to obtain the fundamental data to analyze the causes of deterioration of 39 freeway concrete viaducts in Seoul metropolitan area. To investigate the degree of concrete deterioration, carbonation depth, soluble chloride concentration in hardened concrete and half-cell potentials of reinforcement were measured. The number of structures which carbonation depth penetrates to reinforcement was 25% of total. The model of carbonation .ate was induced to 3.92 $\sqrt{t}$, which was 5% faster than 3.727 $\sqrt{t}$ assumed 60% water-cement ratio, R=1 in that of kishitani. After measuring chloride concentration in concrete, it was concluded that about 24% of all readings on samples from concrete exceed the critical content to minimize the risk of chloride-induced corrosion. About 31% of the freeway viaducts structures had a value lower than -350mV(vs. CSE), so it could conclude that the excessive chloride concentration was the major cause of reinforcement corrosion. Among the structures which measured half-cell potentials less than -350mV, about 50% exceeds the maximum acceptable limit of chloride concentration.

An Analysis of Running Safety for Railway Vehicle Depending on Actual Track Conditions (실제선로 조건에 따른 철도차량의 주행안전성 해석)

  • Kim, Yong-Won;Lee, Hi-Sung
    • Journal of the Korean Society for Railway
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    • v.12 no.6
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    • pp.983-988
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    • 2009
  • When the railway vehicle passing through curves & transitions, the running speed must improve by proposing the practical standard about maximum running possibility speed of each section on existing line considering running safety. In this paper, when the railway vehicle passing through curves of actual track conditions (Namsunghyun-Chungdo up & down lines), the effect that has influence on running safety is examined to devise the high speed of vehicle which passing through curves which risk of derailment is high. The running safety analysis is performed that running speed by curve radius improves 5-20% compared with existing speed under actual track conditions. In result of the running safety analysis, in case the speed condition is fewer than 15% compared with existing speed, the derailment coefficient and unloading ratio are within acceptable level. so we could confirm possibility of speed improvement on the whole Namsunghyun-Chungdo up & down lines.

Total lymphoid irradiation based conditioning for hematopoietic stem cell transplantation in severe aplastic anemia

  • Lee, Yun-Hee;Kim, Ji-Yoon;Choi, Byung-Ock;Ryu, Mi-Ryeong;Chung, Su-Mi
    • Radiation Oncology Journal
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    • v.30 no.4
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    • pp.165-172
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    • 2012
  • Purpose: To retrospectively evaluate the outcome and toxicity of total lymphoid irradiation (TLI) based conditioning regimen for allogeneic hematopoietic stem cell transplantation (HSCT) in severe aplastic anemia (SAA) patients who experienced an engraftment failure from prior HSCT or were heavily transfused. Materials and Methods: Between 1995 and 2006, 20 SAA patients received TLI for conditioning of HSCT. All patients were multi-transfused or had long duration of disease. Fifteen (75%) patients had graft failure from prior HSCT. In 18 (90%) patients, the donors were human leukocyte antigen identical siblings. The stem cell source was the peripheral blood stem cell in 15 (75%) patients. The conditioning regimen was composed of antithymocyte globulin plus TLI with a median dose of 750 cGy in 1 fraction. The graft-versus-host disease (GVHD) prophylaxis used cyclosporine with methotrexate. Results: With a median follow-up of 10.8 years, graft failures developed in 6 patients. Among them, 3 patients received their third HSCT to be engrafted finally. The Kaplan-Meier overall survival rate was 85.0% and 83.1% at 5 and 10 years, respectively. The incidence of acute and chronic GVHD was 20% and 20%, respectively. None of the patients have developed a malignancy after HSCT. Conclusion: In our study, TLI based conditioning in allogeneic HSCT was feasible with acceptable rates of GVHD in SAA patients who experienced graft failure from prior HSCT or was at a high risk of graft rejection. We achieved relatively better results of engraftment and survival with a long term follow-up.

Predictive factors of symptomatic radiation pneumonitis in primary and metastatic lung tumors treated with stereotactic ablative body radiotherapy

  • Kim, Kangpyo;Lee, Jeongshim;Cho, Yeona;Chung, Seung Yeun;Lee, Jason Joon Bock;Lee, Chang Geol;Cho, Jaeho
    • Radiation Oncology Journal
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    • v.35 no.2
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    • pp.163-171
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    • 2017
  • Purpose: Although stereotactic ablative body radiotherapy (SABR) is widely used therapeutic technique, predictive factors of radiation pneumonitis (RP) after SABR remain undefined. We aimed to investigate the predictive factors affecting RP in patients with primary or metastatic lung tumors who received SABR. Materials and Methods: From 2012 to 2015, we reviewed 59 patients with 72 primary or metastatic lung tumors treated with SABR, and performed analyses of clinical and dosimetric variables related to symptomatic RP. SABR was delivered as 45-60 Gy in 3-4 fractions, which were over 100 Gy in BED when the ${\alpha}/{\beta}$ value was assumed to be 10. Tumor volume and other various dose volume factors were analyzed using median value as a cutoff value. RP was graded per the Common Terminology Criteria for Adverse Events v4.03. Results: At the median follow-up period of 11 months, symptomatic RP was observed in 13 lesions (12 patients, 18.1%), including grade 2 RP in 11 lesions and grade 3 in 2 lesions. Patients with planning target volume (PTV) of ${\leq}14.35mL$ had significantly lower rates of symptomatic RP when compared to others (8.6% vs. 27%; p = 0.048). Rates of symptomatic RP in patients with internal gross tumor volume (iGTV) >4.21 mL were higher than with ${\leq}4.21mL$ (29.7% vs. 6.1%; p = 0.017). Conclusions: The incidence of symptomatic RP following treatment with SABR was acceptable with grade 2 RP being observed in most patients. iGTV over 4.21 mL and PTV of over 14.35 mL were significant predictive factors related to symptomatic RP.

Prevalence of considering revision rhinoplasty in Saudi patients and its associated factors

  • Alsubeeh, Najlaa Abdulrahman;AlSaqr, Mayar Abdulsalam;Alkarzae, Mohammed;Aldosari, Badi
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.41
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    • pp.59.1-59.10
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    • 2019
  • Background: Primary rhinoplasty outcomes may not meet individual expectations. Consequently, reoperation may be advocated to improve results. This study examines the prevalence of individuals considering revision rhinoplasty, while identifying the main cosmetic and functional complaints and factors associated. Methodology: This is a cross-sectional study conducted in Saudi Arabia using a self-reported online questionnaire distributed through social media channels. The sample included 1370 participants who were all Saudi nationals over the age of 16 who had undergone primary rhinoplasty at least 1 year prior. Results: The prevalence of individuals considering revision rhinoplasty was 44.7%. The primary reason for considering it was the desire for further esthetic improvement in an already acceptable result (50.16%). The most common cosmetic complaints subjectively reported were poorly defined nasal tip (32.35%). The most prevalent nasal function symptom was nasal obstruction (56.9%). Significant factors associated with considering revision rhinoplasty included the physician not understanding the patient's complaints, short consultation time, low monthly income, inadequate information about the expected results, not using computer imaging to predict outcomes, lack of rapport with the surgeon, and inadequate information about the risks and complications. Conclusions: A thorough understanding of patient concerns and expectations, as well as thoughtful consideration of risk factors, may help surgeons achieve more successful outcomes and potentially reduce the incidence of revision rhinoplasties. Level of evidence: III.

A Study on the Foot and Ankle Disease of Shelter-based Homeless People (노숙인 거주 시설의 족부 족관절 실태에 대한 조사)

  • Min, Hak-Jin;Kim, Ki Chun;Kim, Jae Woo
    • Journal of Korean Foot and Ankle Society
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    • v.21 no.4
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    • pp.156-164
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    • 2017
  • Purpose: Foot and ankle disease (FAD) is a frequent cause of morbidity among the homeless population. Various conditions, exacerbated by malnutrition, poor lifestyle habits, psychiatric disorders, physical injuries, poor hygiene, and limited access to healthcare, have been described in this population. The purpose of this study was to investigate the cognition and management status of FAD in shelter based homeless people. Materials and Methods: Fifty-two male and twenty-five female volunteer homeless individuals were recruited from two homeless shelters. Each person completed a questionnaire assessing any presence of pain, pain management, as well as foot and ankle care status. A foot and ankle surgeon examined the physical status of the individual's foot and ankle, including tenderness and instability. A radiologic evaluation was done for 18 male and 11 female homeless people who agreed to participate in this test for the existence osteophyte or joint space narrowing representing osteoarthritis and some reference angles for hallux valgus, flatfoot and cavus foot. Results: Homeless people had higher prevalence of body mass index, diabetes, and smoking than the general population. The most prevalent infectious disease was fungal infection (male 78%, female 68%), with a low compliance of management for FAD. Conclusion: Although most of shelter-based homeless people showed an acceptable foot and ankle management status, the potential risk for FAD development and exacerbation of mild FAD was high.

The Relations among Attitude, Competency, and Appropriateness of Work on Student Suicide in Health Teachers (일 지역 보건교사의 자살에 대한 태도와 학생 자살 관련 업무 적합도 및 업무수행 역량과의 관련성)

  • Yoo, Jae Soon;Han, Dallong;Kim, Chul-Gyu
    • The Journal of Korean Academic Society of Nursing Education
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    • v.22 no.4
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    • pp.473-484
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    • 2016
  • Purpose: The purpose of this study was to identify the relations among appropriateness of work, competency on student suicide and attitude toward suicide in health teachers. Methods: This study was a cross-sectional descriptive one. The subjects were 193 health teachers. Self-administered questionnaires were used to measure the variables of this study. Descriptive statistics, independent t-test, one way ANOVA, Pearson correlation, and stepwise multiple regression with SAS 9.3 software were used for the data analysis. Results: The attitude score toward suicide ranged from 1.47 to -1.03. The average score of appropriateness of work and competency related to student suicide were 2.34 and 2.81 respectively. Associated factors with competency related to student suicide among health teacher were appropriateness of work related to student suicide, two items of attitude toward suicide(suicide is an acceptable means to end an incurable illness and people who commit suicide are usually mentally ill), education level, education experience on suicide prevention and management, and the adjusted $R^2$ of the regression model was 34.3%. Conclusion: Health teachers were not tolerable to student suicide. However, they evaluated themselves as low in the appropriateness and competency to the work on student suicide, especially in screening and counselling of high risk groups. The results of this study suggest that it is necessary to develop education programs about counseling and intervention on student suicide for health teachers.

Detection of Foodborne Pathogens and Mycotoxins in Eggs and Chicken Feeds from Farms to Retail Markets

  • Lee, Minhwa;Seo, Dong Joo;Jeon, Su Been;Ok, Hyun Ee;Jung, Hyelee;Choi, Changsun;Chun, Hyang Sook
    • Food Science of Animal Resources
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    • v.36 no.4
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    • pp.463-468
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    • 2016
  • Contamination by foodborne pathogens and mycotoxins was examined in 475 eggs and 20 feed samples collected from three egg layer farms, three egg-processing units, and five retail markets in Korea. Microbial contamination with Salmonella species, Escherichia coli, and Arcobacter species was examined by bacterial culture and multiplex polymerase chain reaction (PCR). The contamination levels of aflatoxins, ochratoxins, and zearalenone in eggs and chicken feeds were simultaneously analyzed with high-performance liquid chromatography coupled with fluorescence detection after the post-derivatization. While E. coli was isolated from 9.1% of eggs, Salmonella species were not isolated. Arcobacter species were detected in 0.8% of eggs collected from egg layers by PCR only. While aflatoxins, ochratoxins, and zearalenone were found in 100%, 100%, and 85% of chicken feeds, their contamination levels were below the maximum acceptable levels (1.86, 2.24, and 147.53 μg/kg, respectively). However, no eggs were contaminated with aflatoxins, ochratoxins, or zearalenone. Therefore, the risk of contamination by mycotoxins and microbes in eggs and chicken feeds is considered negligible and unlikely to pose a threat to human health.

Development and Application of a Method for Rapid and Simultaneous Determination of Three β-agonists (Clenbuterol, Ractopamine, and Zilpaterol) using Liquid Chromatography-tandem Mass Spectrometry

  • Sung, In Kyung;Park, Seo Jung;Kang, Kyutae;Kim, Min Young;Cho, Seongbeom
    • Food Science of Animal Resources
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    • v.35 no.1
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    • pp.121-129
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    • 2015
  • ${\beta}$-agonists are anabolic compounds that promote fat loss and muscle gain, and their administration to livestock may provide economic benefits by increasing growth rate and feed efficiency. For these reasons, ${\beta}$-agonists are also commonly added to livestock feed as growth promoters. This can introduce a significant risk of secondary human poisoning through intake of contaminated meat. A new method for the simultaneous determination of three ${\beta}$-agonists (clenbuterol, ractopamine, and zilpaterol) was developed in this study and applied to various meat samples. The limits of quantification, derived through a validation test following Codex guidelines, were $0.2{\mu}g/kg$ for clenbuterol and zilpaterol, and $0.4{\mu}g/kg$ for ractopamine. The average recoveries for clenbuterol, ractopamine, and zilpaterol ranged from 109.1% to 118.3%, 95.3% to 109.0%, and 94.1% to 120.0%, respectively. The recovery and coefficient of variation (CV) values fell within the acceptable range according to the Codex guidelines. This method reduced the analysis time without decreasing detection efficiency by modifying the pretreatment steps. This method could be utilized to manage the safety of imported meat products from countries where zilpaterol use is still permitted, thereby improving public health and preventing ${\beta}$-agonist poisoning due to secondary contamination.