• Computers and Concrete
• /
• v.30 no.4
• /
• pp.277-287
• /
• 2022

Due to the scarcity of extortionate experimental data, fatigue failure of the reinforced concrete (RC) element might be achieved economically adopting nonlinear finite element (FE) analysis as an alternative approach. However, conventional implicit dynamic analysis is expensive, quasi-static method overlooks interaction effects and inertia, direct cyclic analysis computes stabilized responses. Apart from this, explicit dynamic analysis may provide a numerical operating system for factual long-term responses. The study explores the fatigue behavior based on a simplified explicit dynamic solution employing nonlinear time domain analysis. Among fourteen RC beams, one beam is selected to validate under static loading, one under fatigue with the experimental study and other twelve to check the detail fatigue behavior. The SWOT (Strength, Weakness, Opportunities, Threats) analysis has been carried out to pinpoint the detail scenario in the adoption of numerical approach as an alternative to the experimental study. Excellent agreement of FE and experimental results is seen. The 3D nonlinear RC beam model at service fatigue limits is truthful to be used as an expedient contrivance to envisage the precise fatigue behavior. The simplified analysis approach for RC beam under fatigue offers savings in computation to predict responses providing acceptable accuracy rather than the complicated laboratory investigation. At higher frequency, the flexural failure occurs a bit earlier gradually compared to the repeated loading case of lower frequency. The deflection increases by 6%-10% at the end of first cycle for beams with increasing frequency of cyclic loading. However, at the end of fatigue loading, greater deflection occur earlier for higher load range because of more rapid stiffness degradation. For higher frequency, a slight boost in concrete compressive strains at an initial stage of loading has been seen indicating somewhat stepper increment. Stiffness degradation in larger loading cycle at same duration escalates the upsurge of the rate of strain in case of higher frequency.

• Nutrition Research and Practice
• /
• v.16 no.6
• /
• pp.789-800
• /
• 2022

BACKGROUND/OBJECTIVES: The aim of this study was to examine the validity and reproducibility of a food frequency questionnaire (FFQ) developed in Korea for breast cancer survivors. SUBJECTS/METHODS: Ninety-nine breast cancer survivors who completed an FFQ twice and three 3-day dietary records (DRs) between 2016-2017 were included. Energy and 14 nutrient intakes were calculated from FFQs and DRs. To determine the validity of the FFQ, energy-adjusted de-attenuated Pearson correlations between two FFQ assessments and the average of the three 3-day DRs were calculated, and to determine reproducibility, energy-adjusted Pearson correlations and degrees of agreement were calculated between the first and second FFQ assessments. RESULTS: Correlation coefficients of validity ranged from 0.29 (protein) to 0.47 (fat) (median value = 0.36) for the FFQ assessment and from 0.20 (riboflavin) to 0.53 (calcium) (median value = 0.37) for the second. Correlation coefficients of reproducibility ranged from 0.22 (sodium) to 0.62 (carbohydrate) (median value = 0.36). Regarding FFQ reproducibilities, percentage classifications of exact agreements for energy-adjusted nutrients ranged from 27.3% (sodium) and 45.5% (fat). A median 76.8% of participants were classified into the same or adjacent quartiles, while a median of 5.6% of participants were classified in extreme quartiles. Bland-Atman plots for the majority of data points of three macronutrients, calcium and vitamins A and C fell within limits of agreement. CONCLUSIONS: These results indicated that the newly developed FFQ for Korean breast cancer survivors has acceptable validity and reproducibility as compared with three 3-day DRs collected over a one-year period.

• The Journal of Advanced Prosthodontics
• /
• v.14 no.6
• /
• pp.335-345
• /
• 2022

PURPOSE. This in vitro study aimed to evaluate the surface characteristics of a full veneer crown fabricated chairside (CS) from a (Y, Nb)-TZP zirconia block in response to conventional zirconia grinding and polishing. MATERIALS AND METHODS. Zirconia crowns (n = 40) were first prepared and divided into two groups of materials: Labside (LS) and CS, after which each specimen went through a five-step grinding and polishing procedure. Following each surface treatment, surface characteristics were analyzed using confocal laser microscopy (CLSM), average surface roughness (Ra) values were processed from the profile data through Gaussian filtering, and X-ray diffraction pattern analysis was performed to evaluate the monoclinic (M) phase content. Then, a representative specimen was selected for field-emission scanning electron microscopy (FE-SEM), followed by a final analysis of the roughness and X-ray diffraction of the specimens using the independent t-test and repeated measures analysis of variance (RM-ANOVA). RESULTS. In every group, polishing significantly reduced the Ra values (P < .001). There was no significant difference in Ra between the polished state CS and LS. Furthermore, CLSM and FE-SEM investigations revealed that even though grain exposure was visible in CS specimens throughout the as-delivered and ground states, the exposure was reduced after polishing. Moreover, while no phase transformation was visible in the LS, phase transformation was visible in CS after every surface treatment, with the M phase content of the CS group showing a significant reduction after polishing (P < .001). CONCLUSION. Within the limits of this study, clinically acceptable level of surface finishing of (Y, Nb)-TZP can be achieved after conventional zirconia polishing sequence.

• Animal Bioscience
• /
• v.35 no.12
• /
• pp.1977-1985
• /
• 2022

Objective: This study was conducted to determine the seasonal characteristics of odorous material emissions from a swine finishing barn equipped with a continuous pit recirculation system (CPRS) using aerobically treated manure. Methods: The CPRS consists of an aerobic manure treatment process and a pit recirculation system, where the solid fraction is separated and composted. The aerated liquid fraction (290.0%±21.0% per day of total stored pig slurry) is continuously recirculated to the top of the slurry in the pit. Four confinement pig barns in three piggery farms were used: two were equipped with CPRS, and the other two operated a slurry pit under the slatted floor across all seasons. Results: The indoor, exhaust, and outside odor intensities were significantly lower in the CPRS group than in the control group (p<0.001). In the CPRS group, the odor intensity outside was significantly lower in the fall than in the other seasons (p = 0.015). In the indoor atmosphere, the temperature and CO₂, NH₃, and H₂S contents of the CPRS group were significantly lower than those of the control group (p<0.05). In the CPRS group, indoor temperature did not significantly change in the spring, summer, and fall seasons and was significantly lower in the winter (p = 0.002). NH₃, H₂S, methyl mercaptan, dimethyl disulfide, trimethylamine, phenol, indole, and skatole levels were significantly lower in the CPRS group than in the control group (p<0.05). There were significant seasonal differences on the odorous material in both the control and CPRS groups (p<0.05), but the pattern was not clear across seasons. Conclusion: The CPRS can reduce the indoor temperature in the summer to a level similar to that in the spring and fall seasons. The CPRS with aerated liquid manure is expected to reduce and maintain malodorous emissions within acceptable limits in swine facilities.

• Steel and Composite Structures
• /
• v.47 no.2
• /
• pp.167-184
• /
• 2023

In this study, a new recentering friction device (RFD) to retrofit steel moment frame structures is introduced. The device provides both self-centering and energy dissipation capabilities for the retrofitted structure. A hybrid performance-based seismic design procedure considering multiple limit states is proposed for designing the device and the retrofitted structure. The design of the RFD is achieved by modifying the conventional performance-based seismic design (PBSD) procedure using computational intelligence techniques, namely, genetic algorithm (GA) and artificial neural network (ANN). Numerous nonlinear time-history response analyses (NLTHAs) are conducted on multi-degree of freedom (MDOF) and single-degree of freedom (SDOF) systems to train and validate the ANN to achieve high prediction accuracy. The proposed procedure and the new RFD are assessed using 2D and 3D models globally and locally. Globally, the effectiveness of the proposed device is assessed by conducting NLTHAs to check the maximum inter-story drift ratio (MIDR). Seismic fragilities of the retrofitted models are investigated by constructing fragility curves of the models for different limit states. After that, seismic life cycle cost (LCC) is estimated for the models with and without the retrofit. Locally, the stress concentration at the contact point of the RFD and the existing steel frame is checked being within acceptable limits using finite element modeling (FEM). The RFD showed its effectiveness in minimizing MIDR and eliminating residual drift for low to mid-rise steel frames models tested. GA and ANN proved to be crucial integrated parts in the modified PBSD to achieve the required seismic performance at different limit states with reasonable computational cost. ANN showed a very high prediction accuracy for transformation between MDOF and SDOF systems. Also, the proposed retrofit showed its efficiency in enhancing the seismic fragility and reducing the LCC significantly compared to the un-retrofitted models.

• Journal of Korean Society of Coastal and Ocean Engineers
• /
• v.35 no.3
• /
• pp.49-56
• /
• 2023

The allowable mean overtopping discharge is used as a design parameter for coastal structures. The crest elevation of coastal structures should ensure the wave overtopping discharge within acceptable limits for structural safety and the safety of pedestrians, vehicles, operations, and so on. In this study, two-dimensional physical model tests on typical rubble-mound structure geometries were performed and the the mean wave overtopping discharges under various water depth and wave conditions were measrued. The various test conditions were applied to the tests with the change of the wave steepness, relative freeboard and relative wave height. An empirical formula from the experimental data was proposed to predict the mean wave overtopping volumes.

• Food Science of Animal Resources
• /
• v.42 no.2
• /
• pp.295-312
• /
• 2022

Inulin is a non-digestible carbohydrate and a prebiotic that can also act as a fat replacer in various foods. This study examined the effect of replacing vegetable oil with garlic inulin on the quality traits of chicken sausages. Water-based inulin gels were prepared using garlic inulin or commercial inulin to imitate fats in chicken sausages. Chicken sausages were prepared separately replacing vegetable oil with water-based inulin gels to reach final inulin percentages of 1, 2, and 3 (w/w). The control was prepared using 3% (w/w) vegetable oil with no inulin. The physicochemical properties and thiobarbituric acid reactive substance (TBARS) value of prepared sausages were analyzed over 28-d frozen storage. Sausages with 2% garlic inulin recorded higher flavour and overall acceptability scores (p<0.05). Ash, moisture, and protein contents of the sausages were increased with increasing levels of inulin while fat content was reduced from 13.67% (control) to 4.47%-4.85% (p<0.05) in 3% inulin-incorporated products. Sausages incorporated with 2% inulin had lower lightness (L^*) values than the control (p<0.05). Water holding capacity (WHC) was similar (p>0.05) among the samples. During storage L^* value, pH, and WHC decreased while redness (a^*) and yellowness (b^*) values increased in all the samples. In addition, TBARS values were increased during the storage in all samples within the acceptable limits. In conclusion, garlic inulin can be used successfully as a fat substitute in sausages without altering meat quality parameters.

• Journal of The Korean Astronomical Society
• /
• v.55 no.1
• /
• pp.11-22
• /
• 2022

We introduce the Transformable Reflective Telescope (TRT) kit that applies an aluminum profile as a base plate for precise, stable, and lightweight optical system. It has been utilized for optical surface measurements, developing alignment and baffle systems, observing celestial objects, and various educational purposes through Research & Education projects. We upgraded the TRT kit using the aluminum profile and truss and isogrid structures for a high-end optical test device that can be used for prototyping of precision telescopes or satellite optical systems. Thanks to the substantial aluminum profile and lightweight design, mechanical deformation by self-weight is reduced to maximum 67.5 ㎛, which is an acceptable misalignment error compared to its tolerance limits. From the analysis results of non-linear vibration simulations, we have verified that the kit survives in harsh vibration environments. The primary mirror and secondary mirror modules are precisely aligned within 50 ㎛ positioning error using the high accuracy surface finished aluminum profile and optomechanical parts. The cross laser module helps to align the secondary mirror to fine-tune the optical system. The TRT kit with the precision aluminum mirror guarantees high quality optical performance of 5.53 ㎛ Full Width at Half Maximum (FWHM) at the field center.

• The Korean Journal of Physiology and Pharmacology
• /
• v.28 no.3
• /
• pp.275-284
• /
• 2024

Worldwide, cardiovascular disease is the main cause of death, which accordingly increased by hyperlipidemia. Hyperlipidemia therapy can include lifestyle changes and medications to control cholesterol levels. Statins are the medications of the first choice for dealing with lipid abnormalities. Rosuvastatin founds to control high lipid levels by hindering liver production of cholesterol and to achieve the targeted levels of low-density lipoprotein cholesterol, another lipid lowering agents named ezetimibe may be used as an added therapy. Both rosuvastatin and ezetimibe have low bioavailability which will stand as barrier to decrease cholesterol levels, because of such depictions, formulations of this combined therapy in nanotechnology will be of a great assistance. Our study demonstrated preparations of nanoparticles of this combined therapy, showing their physical characterizations, and examined their behavior in laboratory conditions and vivo habitation. The mean particle size was uniform, polydispersity index and zeta potential of formulations were found to be in the ranges of (0.181-0.72) and (-13.4 to -6.24), respectively. Acceptable limits of entrapment efficiency were affirmed with appearance of spherical and uniform nanoparticles. In vitro testing showed a sustained release of drug exceeded 90% over 24 h. In vivo study revealed an enhanced dissolution and bioavailability from loaded nanoparticles, which was evidenced by calculated pharmacokinetic parameters using triton for hyperlipidemia induction. Stability studies were performed and assured that the formulations are kept the same up to one month. Therefore, nano formulations is a suitable transporter for combined therapy of rosuvastatin and ezetimibe with improvement in their dissolution and bioavailability.

• Korean Journal of Radiology
• /
• v.21 no.4
• /
• pp.450-461
• /
• 2020

Objective: We performed a meta-analysis to evaluate the agreement of cardiac computed tomography (CT) with cardiac magnetic resonance imaging (CMRI) in the assessment of right ventricle (RV) volume and functional parameters. Materials and Methods: PubMed, EMBASE, and Cochrane library were systematically searched for studies that compared CT with CMRI as the reference standard for measurement of the following RV parameters: end-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV), or ejection fraction (EF). Meta-analytic methods were utilized to determine the pooled weighted bias, limits of agreement (LOA), and correlation coefficient (r) between CT and CMRI. Heterogeneity was also assessed. Subgroup analyses were performed based on the probable factors affecting measurement of RV volume: CT contrast protocol, number of CT slices, CT reconstruction interval, CT volumetry, and segmentation methods. Results: A total of 766 patients from 20 studies were included. Pooled bias and LOA were 3.1 mL (-5.7 to 11.8 mL), 3.6 mL (-4.0 to 11.2 mL), -0.4 mL (5.7 to 5.0 mL), and -1.8% (-5.7 to 2.2%) for EDV, ESV, SV, and EF, respectively. Pooled correlation coefficients were very strong for the RV parameters (r = 0.87-0.93). Heterogeneity was observed in the studies (I² > 50%, p < 0.1). In the subgroup analysis, an RV-dedicated contrast protocol, ≥ 64 CT slices, CT volumetry with the Simpson's method, and inclusion of the papillary muscle and trabeculation had a lower pooled bias and narrower LOA. Conclusion: Cardiac CT accurately measures RV volume and function, with an acceptable range of bias and LOA and strong correlation with CMRI findings. The RV-dedicated CT contrast protocol, ≥ 64 CT slices, and use of the same CT volumetry method as CMRI can improve agreement with CMRI.