• 환경영향평가
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• 제23권4호
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• pp.296-314
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• 2014

우리나라의 공공하수처리시설 방류수 수질기준을 마련하는데 있어 기준설정 근거를 명확히 하는 것과 하수처리시설의 운영조사를 근거로 적정성 여부를 검토할 수 있는 종합적인 기준설정 체계를 마련할 필요가 있다. 미국은 연방정부가 POTW에 대한 최소한의 항목과 기준의 가이드라인을 제시하며, 지방정부는 국가 가이드라인과 동일하거나 주별 특성을 반영하여 보다 엄격한 가이드라인을 제시하도록 하고 있다. 일본의 경우 하수도법상 방류수 수질기준에서 하수처리시설 구조 기술상의 기준을 만족하여야 하고 방류수 수질기준과 공공수역으로의 배수기준을 동시에 적용하도록 하고 있으며 이에 대한 세부항목 및 기준은 지자체 조례로 규정하고 있다. 유럽의 경우 하수처리시설 방류수 수질기준은 공공수역에 대한 부영양화의 민감성에 따라 수질기준 항목을 차등하여 적용하고, 수계로 배출되는 오염물질 부하량에 따라 수질기준을 차등하여 적용하고 있다. 우리나라도 공공하수처리시설 방류수 수질기준 설정 시 미국 국가오염물질배출삭감제도 또는 유럽 통합환경관리제도에서와 같이 통계적 평균값 및 처리효율 또는 최적처리기술을 적용한 방류수 수질기준을 설정하는 체계를 도입하는 것이 필요하다.

• 농약과학회지
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• 제9권1호
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• pp.51-59
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• 2005

우리나라의 식품중 농약잔류허용기준 설정은 GAP에 의한 과학적인 자료, 농약 1일 섭취허용량(ADI), 식품섭취량, 평균체중 등을 기본으로 하여 설정된다. 농약잔류허용기준은 일반적으로 이론적인 농약섭취량(TMDI)은 ADI보다 낮게 설정된다. 연구결과를 보면, 104개 기준이 24개 농약에 대하여 새롭게 설정되며, 102개 기준이 이미 기준이 설정된 63개 농약에 추가 설정된다. 신규 농약중에 ethaboxam과 flupyra-zofos 농약의 유효성분은 우리나라에서 처음으로 개발되었다. 디치오카바메이트계 농약의 잔류허용기준은 디메칠디치오카바메이트(Dimethyldithiocarbamates), 에칠렌비스디치오카바메이트[Ethylenebis(dithiocarbamate)s] 및 프로피네브(Propineb) 3개 그룹으로 분류하여 신설하였다.

• Nuclear Engineering and Technology
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• 제27권4호
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• pp.562-570
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• 1995

근래의 ABB/CE형 가압경수로들은, 정상운전 및 예상운전과도상태 중에 허용핵연료설계제한치가 위배되는 것을 방지하기 위하여, 노심 운전상태를 감시하는 디지탈노심감시계통, COLSS(Core Oper-ating Limit Supervisory System)를 보유하고있다. COLSS의 주요 기능 중 하나는. 측정되는 운전조건에 대한 최소 핵비등이탈률을 계산하여, 핵비등이탈에 대한 과출력여유도를 감시하는 것이다. COL-SS에서 최소 핵비등이탈률을 계산하는데 사용되는 CETOP-D 모델은 상세부수로분석코드인 TORC 모델에 대해 보수적으로 벤치마킹되며, 보정상수로서 고온집 합체의 입구유량인자를 사용하고 있다. 본 연구에서는 CETOP-D 입구유량인자를 가장 제한적인 운전조건에서 보수적인 단일 값으로 결정하는 ABB/CE 방법을 배제하고, 운전조건에 따른 CETOP-D 입구유량인자 변화를 상관식형태로 결정하는 “CETOP-D 입구유량인자 최적화기법”을 개발하였다. 개발된 방법을 영광 3,4호기 초기노심의 노심운전영역에 적용한 결과, 기존의 ABB/CE 방법에 비하여 정상운전영역에서 핵비등이탈에 대한 과출력여유도가 2% 가량 증가하였다.

• 한국간호교육학회지
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• 제4권2호
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• pp.264-279
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• 1998

This study researches the attitudes of nursing students toward induced abortion. It aims to Identify the structure of subjectivity of nursing students toward induced abortion. As the research method, Q-statements were collected preliminary to the study through in-depth group talking, case study and literature review. For the study, 28 Q-statements were selected. There were 40 students as subjects for the research. The 40 students sorted the 28 statements using the principle of Forced Normal Distribution. The results of the study were as follows : Three attitude types toward induced abortion were derived from Q-Factor analysis by using PC Quanal Program. The first type is called qualified deontology type. The second type is called rational utility type. The third type is called self-centered utility type. 1) Qualified deontology type emphasizes the importance of respect for life. Induced abortion is acceptable within just limit circumstances. 2) Rational utility type has more tolerance limits. There are rationale for induced abortion. Thls type hates becoming the target of criticism because they are single mothers, were rape or had a deformed baby. 3) Self-centered utility type believe that the most important in the world is one's self. This type emphasizes the importance of women's autonomy. And then the woman should be able to decide about abortion, because it is her body, it is her choice. The result of the study suggests that nursing education need more ethical teaching of the importance of human life. Be cause the fundmental concept of nursing is in the preservation of human life and in the respect for life, dignity and the rights of man. Nursing ethics is a essential for nurses.

• Restorative Dentistry and Endodontics
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• 제37권3호
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• pp.149-154
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• 2012

Objectives: To evaluate the accuracy of the Root ZX in teeth with simulated root perforation in the presence of gel or liquid type endodontic irrigants, such as saline, 5.25% sodium hypochlorite (NaOCl), 2% chlorhexidine liquid, 2% chlorhexidine gel, and RC-Prep, and also to determine the electrical conductivities of these endodontic irrigants. Materials and Methods: A root perforation was simulated on twenty freshly extracted teeth by means of a small perforation made on the proximal surface of the root at 4 mm from the anatomic apex. Root ZX was used to locate root perforation and measure the electronic working lengths. The results obtained were compared with the actual working length (AWL) and the actual location of perforations (AP), allowing tolerances of 0.5 or 1.0 mm. Measurements within these limits were considered as acceptable. Chi-square test or the Fisher's exact test was used to evaluate significance. Electrical conductivities of each irrigant were also measured with an electrical conductivity tester. Results: The accuracies of the Root ZX in perforated teeth were significantly different between liquid types (saline, NaOCl) and gel types (chlorhexidine gel, RC-Prep). The accuracies of electronic working lengths in perforated teeth were higher in gel types than in liquid types. The accuracy in locating root perforation was higher in liquid types than gel types. 5.25% NaOCl had the highest electrical conductivity, whereas 2% chlorhexidine gel and RC-Prep gel had the lowest electrical conductivities among the five irrigants. Conclusions: Different canal irrigants with different electrical conductivities may affect the accuracy of the Root ZX in perforated teeth.

• Bulletin of the Korean Chemical Society
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• 제32권5호
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• pp.1547-1553
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• 2011

An effective analytical method of gas chromatography/mass spectrometry (GC/MS) was developed for the rapid determination of essential oils in the crude extract of Acorus species (Acorus gramineus, Acorus tatarinowii, and Acorus calamus). Major phenypropanoids (${\beta}$,${\alpha}$-asarone isomers, euasarone, and methyleugenol) and ${\beta}$-caryophyllene in Acorus species were used as marker compounds and determined for the quality control of herbal medicines. To extract marker compounds, various extraction techniques such as solvent immersion, mechanical shaking, and sonication were compared, and the greatest efficiency was observed with sonication extraction using petroleum ether. The dynamic range of the GC/MS method depended on the specific analyte; acceptable quantification was obtained between 10 and 2000 ${\mu}g/mL$ for ${\beta}$-asarone, 10 and 500 ${\mu}g/mL$ for ${\alpha}$-asarone, 10 and 200 ${\mu}g/mL$ for methyleugenol, and between 5 and 100 ${\mu}g/mL$ for ${\beta}$-caryophyllene. The method was deemed satisfactory by inter- and intra-day validation and exhibited both high accuracy and precision, with a relative standard deviation < 10%. Overall limits of detection were approximately 0.34-0.83 ${\mu}g/mL$, with a standard deviation (${\sigma}$)-to-calibration slope (s) ratio (${\sigma}$/s) of 3. The limit of quantitation in our experiments was approximately 1.13-3.20 ${\mu}g/mL$ at a ${\sigma}$/s of 10. On the basement of method validation, 20 samples of Acorus species collected from markets in Korea were monitored for the quality control. In addition, principal component analysis (PCA) and hierarchical cluster analysis (HCA) were performed on the analytical data of 20 different Acorus species samples in order to classify samples that were collected from different regions.

• Bulletin of the Korean Chemical Society
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• 제34권7호
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• pp.2081-2085
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• 2013

A quantitative method for determining levels of three bioactive compounds based on pattern recognition was developed and fully validated for the quality control of Alismatis Rhizoma (AR) by HPLC. Separation conditions were optimised using an Optimapak $C_{18}$ column ($250mm{\times}4.6mm$, 5 ${\mu}m$) with a mobile phase of acetonitrile and 0.1% aqueous phosphoric acid and detection wavelengths of 205 and 245 nm. Method validation yielded acceptable linearity ($r^2$ > 0.9998) and percent recovery (98.06%-101.71%). Limits of detection ranged from 0.08 to 0.15 ${\mu}g/mL$. Levels of the three bioactive compounds, alisol C acetate, alisol B, and alisol B acetate, in AR were 0.07-0.45, 0.38-10.32, and 1.13-8.59 mg/g dried weight, respectively. Pattern analyses based on these three compounds were able to differentiate Chinese and Korean samples accurately. The results demonstrate that alisol B and its acetate may be used as marker compounds for AR quality and can be regulated to no less than 0.36 and 1.29 mg/g of dried sample, respectively. The method described here is suitable for quantitative analyses and quality control of multiple components in AR.

• 전자공학회논문지
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• 제53권8호
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• pp.107-112
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• 2016

원자력발전소의 안전필수 기능을 수행하는 계측제어 시스템은 원자로의 예상되는 과도상태가 발생되거나 설계기준사고의 결과를 완화하기 위해 원자로 및 주요 기기의 상태를 감시한다. 만일 원자로출력, 냉각재 온도, 또는 증기발생기 수위 등의 상태가 기 정해진 설정치에 도달하게 되면 정확하고 신속하게 원자로를 정지시키는 기능을 수행한다. 이러한 안전필수 시스템은 예상 가능한 사고로부터 인간과 자연을 보호하기 위한 중요 기능을 수행하는 디지털 제어시스템으로써, 비인가 된, 의도되지 않은 변경 등의 취약점으로 인해 신뢰성 있는 운영이 영향을 받지 않도록 보안성환경이 구축되어야 한다. 이러한 보안성환경은 관리적 조치와 기술적 조치를 통해 구현될 수 있다. 본 논문에서는 안전필수 기능을 수행하는 원전 계측제어 시스템의 제어용 소프트웨어 진단기능이 보안성환경을 구축하는 데 효과적인 설계방안인지를 평가하였다. 이를 위해, 제어용 소프트웨어의 무결성을 확인하는 순환잉여검사(CRC) 진단기능에 대한 모의실험을 수행하였다. 본 논문에서의 효과성 평가는 향후 안전필수기능을 수행하는 원전 계측제어 시스템의 설계 및 안전성 분석에 활용될 수 있을 것으로 기대된다.

• 한국임상수의학회지
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• 제8권1호
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• pp.31-45
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• 1991

Present experiment was performed in order to establish the optimal reaction conditions for determination of urinary AAP and GRS activities and to investigate the applicability of urinary AAP and GRS in nephrotoxicity test in rat. The results were as follows ; 1. The optimal pH of phosphate buffer for determination of urinary AAP activity was 7.8. 2. The Michaelis constant of urinary AAP ranged from 0.8 to 1.0mmol/$\ell$ 3. The optimal wave length for determination of urinary GRS activity was 405nm. 4. The optimal pH of acetate buffer for determination of urinary GRS activity was 5.6. 5. The Michaelis constant of urinary GRS ranged from 0.65~0.79mmo1/$\ell$. 6. The AAP activities in gel-filtered samples were significantly higher than those in crude samples. Mean values of AAP activities in gel-filtered samples and crude samples were 29$\pm$20 and 20$\pm$13U/$\ell$, respectively. 7. There was not significant difference between gel-filtered samples and crude samples in urinary GRS activities. Mean values of GRS activities in gel-filtered samples and crude samples were 57$\pm$40 and 56$\pm$39U/$\ell$, respectively. 8. Limits of linearity of urinary AAP and GRS activities were 2.0 and 3.6U/$\ell$, respectively. 9. Within-run imprecisions of the assays, were acceptable, as the coefficients of the AAP activities ranged from 5.5 to 6.3% and those of GRS activities ranged from 1.4 to 6.2%, respectively. 10. Urinary AAP excretion was 675$\pm$227mu/24hrs.kg before administration of potassium dichromate, and increased significantly to 4246$\pm$2567mU/24hrs.kg within 24 hours after administration of potassium dichromate. 11. Urinary GRS excretion did not increase significantly after administration of potassim dichromate. 12. From these findings it is concluded that urinary AAP excretion is early and sensitive Indicator to detect kidney damage in nephrotoxicity experiment.

• 한국의학물리학회지:의학물리
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• 제28권3호
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• pp.111-121
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• 2017

Verification of dose distribution is an essential part of ensuring the treatment planning system's (TPS) calculated dose will achieve the desired outcome in radiation therapy. Each measurement have uncertainty associated with it. It is desirable to reduce the measurement uncertainty. A best approach is to reduce the uncertainty associated with each step of the process to keep the total uncertainty under acceptable limits. Point dose patient specific quality assurance (QA) is recommended by American Association of Medical Physicists (AAPM) and European Society for Radiotherapy and Oncology (ESTRO) for all the complex radiation therapy treatment techniques. Relative and absolute point dose measurement methods are used to verify the TPS computed dose. Relative and absolute point dose measurement techniques have a number of steps to measure the point dose which includes chamber cross calibration, electrometer reading, chamber calibration coefficient, beam quality correction factor, reference conditions, influences quantities, machine stability, nominal calibration factor (for relative method) and absolute dose calibration of machine. Keeping these parameters in mind, the estimated relative percentage uncertainty associated with the absolute point dose measurement is 2.1% (k=1). On the other hand, the relative percentage uncertainty associated with the relative point dose verification method is estimated to 1.0% (k=1). To compare both point dose measurement methods, 13 head and neck (H&N) IMRT patients were selected. A point dose for each patient was measured with both methods. The average percentage difference between TPS computed dose and measured absolute relative point dose was 1.4% and 1% respectively. The results of this comparative study show that while choosing the relative or absolute point dose measurement technique, both techniques can produce similar results for H&N IMRT treatment plans. There is no statistically significant difference between both point dose verification methods based upon the t-test for comparing two means.