• International Journal of Highway Engineering
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• v.19 no.6
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• pp.75-81
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• 2017

PURPOSES : So far, aged cement concrete pavement on express highways has been rehabilitated mainly with asphalt concrete inlay. However, potholes were the major problem, and they shortened the life of the inlay mainly owing to the poor drainage of water once it infiltrated the interface of the concrete and asphalt. The purpose of this study is to compare the performance and economic efficiency of asphalt overlay and inlay. METHODS : Overlay and inlay were compared through accelerated pavement testing, and a life-cycle cost analysis was conducted in this study using the CA4PRS program. RESULTS and CONCLUSIONS : It was found from accelerated pavement testing that the overlay exhibited reflective crack resistance that was more than twice as effective as that of inlay. The total cost (construction cost + user cost) within the analysis period (20 years) of the overlay was 37% lower than that of the inlay.

• Proceeding of Spring/Autumn Annual Conference of KHA
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• 2008.04a
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• pp.135-139
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• 2008

A rural area of Korea is inferior compare to urban areas in physical settlements, and an elderly people of the inhabitant increased and it is not easy to see young people in a rural villages. It comes from income difference between industrial type and area and leaving rural area are the accelerated and repeated, and resident who live in rural area after twenty to thirty years can be an elderly society A settlement of rural area is needed settlement rehabilitation for elderly society as follows first, a model development and public support of settlement rehabilitation for rural areas. Second, village remodeling of farming village for elderly are discussed. The rehabilitate rural villages is expected an immigration from urban area which over crowding, and eco tour as new industry.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.8
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• pp.46-54
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• 2016

This study was conducted to investigate the effects of participation in the accelerated rehabilitation with an anti-gravity treadmill program for 16 weeks on isokinetic myofunction and functional score of knee joint, ROM, and VAS score in meniscus repair patients. A total of 10 male adult patients who underwent meniscus repair by the same doctor were investigated in this study. Both extension and flexion peak torque at $60^{\circ}/sec$ and $180^{\circ}/sec$ significantly increased (p<0.001, p<0.01), while under muscle deficit, extension and flexion peak torque at $60^{\circ}/sec$ and extension peak torque at $180^{\circ}/sec$ significantly decreased (p<0.01, p<0.05). ROM in extension significantly decreased (p<0.05), whereas ROM in flexion significantly increased (p<0.01) in response to the program. VAS score significantly decreased (p<0.001) and lysholm scores significantly increased after completion of the program (p<0.001). These results suggest that 16 weeks of the anti-gravity treadmill accelerated rehabilitation program improves isokinetic muscle strength and functional score of knee joint, ROM, and VAS score in meniscus repair patients. Therefore, the anti-gravity treadmill accelerated rehabilitation program, which is a more scientific and effective method than conventional rehabilitation, leads to faster recovery of paly ground and normal daily activities.

• Convergence Security Journal
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• v.13 no.3
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• pp.3-8
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• 2013

Recently, the technology and services make progress in IT sector to facilitate the rehabilitation, as well as the exercise that aims to promote the health. To provide the opportunity for new services, various challenges have to be fulfilled, including the blurring boundaries among industries, spread of new technologies, and various demands. Seizing on this opportunity, the fusion and convergence have been accelerated. The trends towards the fusion and convergence are inherent in content industry and spreading to other sectors, which makes the cultural desire of customers fulfilled in a more diverse manner. In particular, the research has been conducted, using the game, in the new technology cultural contents which have shown noticeable fusion and convergence between IT and exercise rehabilitation areas. Such games can be classified into the motion-based game, serious game, and virtual reality game. Those game contents are forming the market fast based on the contents for education, sports, exercise rehabilitation, healthcare, etc., and have very great potential for growth. This study is intended to analyze the fusion and convergence system of exercise rehabilitation through those games and present a direction for future development.

• Journal of Korean Medicine Rehabilitation
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• v.20 no.3
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• pp.1-11
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• 2010

Objectives : This study was designed to investigate the effects of Lumbricus extract(LE) on the regional cerebral blood flow(rCBF) in ischemic rats, further to determine the mechanism of action of LE, and the effects that LE inhibits lactate dehydrogenase(LDH) activity in brain cells. Methods and materials : This study, ischemic rats were divided into total four group: control group(n=6), experimental group I (LE treated group)(n=6), experimental group II(LE treated group after pretreatment with indomethacin)(n=6), experimental group III(LE treated group after pretreatment with methylene blue)(n=6). And the measurement that LE inhibits LDH activity in the damage to brain cells to N-methyl-D-aspartic acid(NMDA). The changes of rCBF were determinated by laser-doppler flowmetry(LDF), and LDH activity was determinated by microplate reader in vitro. Results : 1. The rCBF was significantly improved by LE(10 mg/kg, i.p.) during the period of cerebral reperfusion, compared with the control group. 2. The rCBF was significantly increased by LE after pretreatment with indomethacin(1 mg/kg, i.p.), an inhibitor of cyclooxygenase, during the period of cerebral reperfusion, compared with the LE group, and rCBF was accelerated by LE after pretreatment with methylene blue($10{\mu}g/kg$, i.p.) an inhibitor of guanylate cyclase during the period of cerebral reperfusion, compared with the control group. 3. LE significantly inhibited LDH activity in vitro in a dose-dependent manner. Conclusions : From the above results, these were suggested that Lumbricus had anti-ischemia action in connection with cyclooxygenase and might prevent the brain cells death through inhibited LDH activity.

• Journal of Korean Physical Therapy Science
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• v.1 no.2
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• pp.333-343
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• 1994

This study was performed to assess the efficacy of electrical stimulation for healing of wound in injured tissue, and to provide a baseline for electrical stimulation in the treatment. Although the specific mechanism by electrical stimulation which may promote injured tissue to heal is not known, generally many hypothesis exist such as bactericidal effect, enhanced circulation, stimulation of cellular biosynthesis and replication, and attraction of connective tissues and inflammatory cells The results of this study are as follows : 1. The healing of skin wound was facilitated by electrical stimulation 2. The capacity of collagen synthesis was significantly accelerated by electrical stimulation 3. The application of electrical stimulation to injured tissue may be helpful in augmenting the rate of wound contracture

• Journal of Biomedical Engineering Research
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• v.29 no.2
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• pp.132-138
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• 2008

We investigated the biomechanical properties of a newly designed self-expansion type anterior cruciate ligament (ACL) anchor. The ACL anchor consists of the ring section giving the elastic force, the wedge for maintaining in contact with the femur tunnel wall and the link suspending hamstring graft or artificial ligament. The main design parameters that determine the performance of this device were the expansion angle (${\theta}$) and the thickness ($t_R$). The Ti6Al4V anchors were heated after inserting in a jig for 1 hour at $800^{\circ}C$ in a protective argon gas atmosphere and allowed to cool to room temperature in the furnace. In order to investigate the influence of the expansion angle and the thickness of the ring on the biomechanical properties of the anchor, the maximum pull-out load, stiffness and slippage of the ACL anchor were measured using the pull-out tester, and statistical analyses were also executed. The present results showed that the design parameters gave a significant effect on the performance of the self- expansion type of anchor. The pull-out load of the ACL anchors significantly increased as the thickness of the ring section was increased, having a similar trend for both expansion angles. The ACL anchor showed about 2.5 times higher values of the pull-out load than that of the minimum load (500N)required for the "accelerated rehabilitation". The optimum ${\theta}$ and $t_R$ values of this ACL anchor were suggested to have sufficient resistance against the pull-out force, high stiffness and relatively low slippage after ACL reconstruction.

• Molecules and Cells
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• v.45 no.6
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• pp.376-387
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• 2022

Extracellular vesicles (EVs) play an essential role in the communication between cells and the tumor microenvironment. However, the effect of tumor-derived EVs on the growth and metastasis of lung adenocarcinoma (LUAD) remains to be explored. This study aimed to elucidate the role of miR-153-3p-EVs in the invasion and migration capabilities of LUAD cells and explore its mechanism through in vivo and in vitro experiments. We found that miR-153-3p was specifically and highly expressed in LUAD and its secreted EVs. Furthermore, the expression of BANCR was negatively regulated by miR-153-3p and identified as a target gene of miR-153-3p using luciferase reporter assays. Through further investigation, we found that the downregulation of BANCR activates the PI3K/AKT pathway and accelerates the process of epithelial-mesenchymal transition (EMT), which ultimately leads to the aggravation of LUAD. The orthotopic xenograft mouse model was established to illustrate the effect of miR-153-3p-EVs on LUAD. Animal studies showed that miR-153-3p-EVs accelerated tumor growth in mice. Besides, we found that miR-153-3p-EVs could damage the respiratory ability of mice and produce a mass of inflammatory cells around the lung tissue of mice. Nevertheless, antagomir-153-3p treatment could inhibit the deterioration of respiratory function and inhibit the growth of lung tumors in mice. In conclusion, our study reveals the potential molecular mechanism of miR-153-3p-EVs in the development of LUAD and provides a potential strategy for the treatment of LUAD.

• Journal of Korean Academy of Nursing
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• v.39 no.1
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• pp.124-135
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• 2009

Purpose: The purpose of this study was to evaluate the service satisfaction for families who have someone with mental illness, and are using community mental health centers in Gyeonggi Province. Methods: The participants in this study were 796 family members. Data were collected using Family satisfaction survey questionnaire developed by the author (23 items on family service and 15 items on client service). Results: The total satisfaction level for the service with family and client resulted in above average scores. Of the 23 service items, data showed the highest level of satisfaction was with professional skills and attitude, and day rehabilitation programs, and the lowest for professional activities for advocacy and social welfare benefits, emergency & crisis intervention, medical expense subsidies. Of the 15 service items, job and housing related service had the lowest level of satisfaction. Conclusion: It is recommended that psychiatric emergency & crisis intervention programs and system development be accelerated. Also, there is a need to develop medical expense subsidy programs for older family caregivers, job and housing focused rehabilitation programs and community facilities for the client, as well as more active and powerful professional advocate activities for persons who have mental disabilities and their families.

• Advances in concrete construction
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• v.7 no.2
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• pp.97-105
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• 2019

In this paper, the workability and static stability were evaluated using a proposed test method. Workability and static stability represent a key property of self-compacting concrete (SCC) in fresh state. A number of standardized test methods were developed to assess these properties. However, no accelerated test method reliably predicts both workability and static stability of SCC. In the present work, a modified K-slump test method was developed to evaluate workability and static stability of SCC. In order to take implicit mixture variations of SCC constituents that can affect fresh SCC properties, a central composite design was adopted to highlight the effect of gravel to sand ratio (G/S), gravel 3/8 to gravel 8/15 ratio (G1/G2), water to cement ratio (W/C), marble powder to cement ratio (MP/C) and superplasticizer content (SP) on workability measured with slump and flow time (T50) tests and static stability measured with sieve stability test (Pi), segregation test index (SSI), Penetration test (Pd) and the proposed K-slump test (Km). The obtained results show that G/S ratio close to 1 and G1/G2 ratio close to 60% can be considered as optimal values to achieve a good workability while ensuring a sufficient static stability of SCC. Acceptable relationships were obtained between Slump flow, Pi, Pd and Km. Results show that the proposed K-slump test allow to assess both workability and static stability of fresh SCC mixtures.