• 한국도로학회논문집
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• 제19권6호
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• pp.75-81
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• 2017

PURPOSES : So far, aged cement concrete pavement on express highways has been rehabilitated mainly with asphalt concrete inlay. However, potholes were the major problem, and they shortened the life of the inlay mainly owing to the poor drainage of water once it infiltrated the interface of the concrete and asphalt. The purpose of this study is to compare the performance and economic efficiency of asphalt overlay and inlay. METHODS : Overlay and inlay were compared through accelerated pavement testing, and a life-cycle cost analysis was conducted in this study using the CA4PRS program. RESULTS and CONCLUSIONS : It was found from accelerated pavement testing that the overlay exhibited reflective crack resistance that was more than twice as effective as that of inlay. The total cost (construction cost + user cost) within the analysis period (20 years) of the overlay was 37% lower than that of the inlay.

• 한국주거학회:학술대회논문집
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• 한국주거학회 2008년도 춘계학술발표대회 논문집
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• pp.135-139
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• 2008

A rural area of Korea is inferior compare to urban areas in physical settlements, and an elderly people of the inhabitant increased and it is not easy to see young people in a rural villages. It comes from income difference between industrial type and area and leaving rural area are the accelerated and repeated, and resident who live in rural area after twenty to thirty years can be an elderly society A settlement of rural area is needed settlement rehabilitation for elderly society as follows first, a model development and public support of settlement rehabilitation for rural areas. Second, village remodeling of farming village for elderly are discussed. The rehabilitate rural villages is expected an immigration from urban area which over crowding, and eco tour as new industry.

• 한국산학기술학회논문지
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• 제17권8호
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• pp.46-54
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• 2016

본 연구의 목적은 16주간의 anti-gravity treadmill program을 적용한 가속재활운동이 반월상연골 봉합술 환자의 슬관절의 등속성 근기능 및 기능점수와 관절가동범위, 통증지수에 어떠한 영향을 미치는 지를 구명하고자 실시되었다. 연구대상자는 슬관절의 반월상연골 파열 진단을 받고 봉합술을 시행한 10명을 대상으로 하였다. 이 연구의 결과에서, 슬관절 등속성 신근력과 굴근력은 16주간의 anti-gravity treadmill program을 적용한 가속재활운동 후, $60^{\circ}/sec$와 $180^{\circ}/sec$에서 모두 유의하게 증가하였으며(p<.001, p<.01), 등속성 근결손율은 $60^{\circ}/sec$에서는 신근력과 굴근력, $180^{\circ}/sec$에서는 신근력이 유의하게 감소한 결과를 나타내었다(p<.01, p<.05). 슬관절 기능점수 또한 가속재활운동 후, 유의하게 증가하였으며(p<.001), 슬관절 가동범위도 가속재활운동 후, 신전의 경우 유의하게 감소하였고(p<.05), 굴곡에서는 유의하게 증가를 나타내었다(p<.01). 시각적사상척도(VAS)를 이용한 주관적 통증지수의 변화는 가속재활운동 후, 유의하게 감소한 결과를 나타내었다(p<.001). 이상의 결과에서, 16주간의 anti-gravity treadmill program을 적용한 가속재활운동은 슬관절의 반월상연골 봉합술 환자의 슬관절 등속성 근기능 및 기능점수와 관절가동범위, 통증지수에 긍정적 효과가 있는 것으로 생각되며 이러한 재활방법은 기존의 전통적 재활방법과 비교하여 보다 안전하고 과학적인 방법으로 빠른 스포츠 현장 및 일상생활로 복귀할 수 있는 가능성이 있는 것으로 사료된다.

• 융합보안논문지
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• 제13권3호
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• pp.3-8
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• 2013

최근 IT분야에서는 건강증진을 위한 운동뿐만 아니라 재활을 목적으로 하는 기술 및 서비스가 진행되고 있다. 새로운 서비스 기회를 제공하기 위해서는 산업분야간 경계약화, 신기술의 확산, 그리고 다양한 수요가 요구되고 있으며 이를 계기로 융복합화 현상이 더욱 가속화되고 있다. 융복합 트렌드는 콘텐츠 산업 전반에 내재되어 또 다른 영역으로 발전하고 있으며, 이는 수요자의 문화적 욕구를 보다 다양하게 충족시키는 역할을 해오고 있다. 특히 IT기술과 운동재활영역의 융합이 두드러지게 나타나는 신기술 문화 콘텐츠에서는 게임을 활용하여 연구가 진행되었으며, 여기에는 체감형 게임, 기능성 게임, 가상현실 게임으로 분류할 수 있다. 이러한 게임콘텐츠는 교육용, 스포츠, 운동재활, 헬스케어 등을 중심으로 빠르게 시장을 형성하고 있으며 그 성장 가능성은 매우 크다고 할 수 있다. 본 연구에서는 이러한 콘텐츠를 활용하여 운동재활이 이루어지는 융복합 체계를 분석하고 향후 발전 방향을 제시하고자 한다.

• 한방재활의학과학회지
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• 제20권3호
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• pp.1-11
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• 2010

Objectives : This study was designed to investigate the effects of Lumbricus extract(LE) on the regional cerebral blood flow(rCBF) in ischemic rats, further to determine the mechanism of action of LE, and the effects that LE inhibits lactate dehydrogenase(LDH) activity in brain cells. Methods and materials : This study, ischemic rats were divided into total four group: control group(n=6), experimental group I (LE treated group)(n=6), experimental group II(LE treated group after pretreatment with indomethacin)(n=6), experimental group III(LE treated group after pretreatment with methylene blue)(n=6). And the measurement that LE inhibits LDH activity in the damage to brain cells to N-methyl-D-aspartic acid(NMDA). The changes of rCBF were determinated by laser-doppler flowmetry(LDF), and LDH activity was determinated by microplate reader in vitro. Results : 1. The rCBF was significantly improved by LE(10 mg/kg, i.p.) during the period of cerebral reperfusion, compared with the control group. 2. The rCBF was significantly increased by LE after pretreatment with indomethacin(1 mg/kg, i.p.), an inhibitor of cyclooxygenase, during the period of cerebral reperfusion, compared with the LE group, and rCBF was accelerated by LE after pretreatment with methylene blue($10{\mu}g/kg$, i.p.) an inhibitor of guanylate cyclase during the period of cerebral reperfusion, compared with the control group. 3. LE significantly inhibited LDH activity in vitro in a dose-dependent manner. Conclusions : From the above results, these were suggested that Lumbricus had anti-ischemia action in connection with cyclooxygenase and might prevent the brain cells death through inhibited LDH activity.

• 대한물리치료과학회지
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• 제1권2호
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• pp.333-343
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• 1994

This study was performed to assess the efficacy of electrical stimulation for healing of wound in injured tissue, and to provide a baseline for electrical stimulation in the treatment. Although the specific mechanism by electrical stimulation which may promote injured tissue to heal is not known, generally many hypothesis exist such as bactericidal effect, enhanced circulation, stimulation of cellular biosynthesis and replication, and attraction of connective tissues and inflammatory cells The results of this study are as follows : 1. The healing of skin wound was facilitated by electrical stimulation 2. The capacity of collagen synthesis was significantly accelerated by electrical stimulation 3. The application of electrical stimulation to injured tissue may be helpful in augmenting the rate of wound contracture

• 대한의용생체공학회:의공학회지
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• 제29권2호
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• pp.132-138
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• 2008

We investigated the biomechanical properties of a newly designed self-expansion type anterior cruciate ligament (ACL) anchor. The ACL anchor consists of the ring section giving the elastic force, the wedge for maintaining in contact with the femur tunnel wall and the link suspending hamstring graft or artificial ligament. The main design parameters that determine the performance of this device were the expansion angle (${\theta}$) and the thickness ($t_R$). The Ti6Al4V anchors were heated after inserting in a jig for 1 hour at $800^{\circ}C$ in a protective argon gas atmosphere and allowed to cool to room temperature in the furnace. In order to investigate the influence of the expansion angle and the thickness of the ring on the biomechanical properties of the anchor, the maximum pull-out load, stiffness and slippage of the ACL anchor were measured using the pull-out tester, and statistical analyses were also executed. The present results showed that the design parameters gave a significant effect on the performance of the self- expansion type of anchor. The pull-out load of the ACL anchors significantly increased as the thickness of the ring section was increased, having a similar trend for both expansion angles. The ACL anchor showed about 2.5 times higher values of the pull-out load than that of the minimum load (500N)required for the "accelerated rehabilitation". The optimum ${\theta}$ and $t_R$ values of this ACL anchor were suggested to have sufficient resistance against the pull-out force, high stiffness and relatively low slippage after ACL reconstruction.

• Molecules and Cells
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• 제45권6호
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• pp.376-387
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• 2022

Extracellular vesicles (EVs) play an essential role in the communication between cells and the tumor microenvironment. However, the effect of tumor-derived EVs on the growth and metastasis of lung adenocarcinoma (LUAD) remains to be explored. This study aimed to elucidate the role of miR-153-3p-EVs in the invasion and migration capabilities of LUAD cells and explore its mechanism through in vivo and in vitro experiments. We found that miR-153-3p was specifically and highly expressed in LUAD and its secreted EVs. Furthermore, the expression of BANCR was negatively regulated by miR-153-3p and identified as a target gene of miR-153-3p using luciferase reporter assays. Through further investigation, we found that the downregulation of BANCR activates the PI3K/AKT pathway and accelerates the process of epithelial-mesenchymal transition (EMT), which ultimately leads to the aggravation of LUAD. The orthotopic xenograft mouse model was established to illustrate the effect of miR-153-3p-EVs on LUAD. Animal studies showed that miR-153-3p-EVs accelerated tumor growth in mice. Besides, we found that miR-153-3p-EVs could damage the respiratory ability of mice and produce a mass of inflammatory cells around the lung tissue of mice. Nevertheless, antagomir-153-3p treatment could inhibit the deterioration of respiratory function and inhibit the growth of lung tumors in mice. In conclusion, our study reveals the potential molecular mechanism of miR-153-3p-EVs in the development of LUAD and provides a potential strategy for the treatment of LUAD.

• 대한간호학회지
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• 제39권1호
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• pp.124-135
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• 2009

Purpose: The purpose of this study was to evaluate the service satisfaction for families who have someone with mental illness, and are using community mental health centers in Gyeonggi Province. Methods: The participants in this study were 796 family members. Data were collected using Family satisfaction survey questionnaire developed by the author (23 items on family service and 15 items on client service). Results: The total satisfaction level for the service with family and client resulted in above average scores. Of the 23 service items, data showed the highest level of satisfaction was with professional skills and attitude, and day rehabilitation programs, and the lowest for professional activities for advocacy and social welfare benefits, emergency & crisis intervention, medical expense subsidies. Of the 15 service items, job and housing related service had the lowest level of satisfaction. Conclusion: It is recommended that psychiatric emergency & crisis intervention programs and system development be accelerated. Also, there is a need to develop medical expense subsidy programs for older family caregivers, job and housing focused rehabilitation programs and community facilities for the client, as well as more active and powerful professional advocate activities for persons who have mental disabilities and their families.

• Advances in concrete construction
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• 제7권2호
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• pp.97-105
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• 2019

In this paper, the workability and static stability were evaluated using a proposed test method. Workability and static stability represent a key property of self-compacting concrete (SCC) in fresh state. A number of standardized test methods were developed to assess these properties. However, no accelerated test method reliably predicts both workability and static stability of SCC. In the present work, a modified K-slump test method was developed to evaluate workability and static stability of SCC. In order to take implicit mixture variations of SCC constituents that can affect fresh SCC properties, a central composite design was adopted to highlight the effect of gravel to sand ratio (G/S), gravel 3/8 to gravel 8/15 ratio (G1/G2), water to cement ratio (W/C), marble powder to cement ratio (MP/C) and superplasticizer content (SP) on workability measured with slump and flow time (T50) tests and static stability measured with sieve stability test (Pi), segregation test index (SSI), Penetration test (Pd) and the proposed K-slump test (Km). The obtained results show that G/S ratio close to 1 and G1/G2 ratio close to 60% can be considered as optimal values to achieve a good workability while ensuring a sufficient static stability of SCC. Acceptable relationships were obtained between Slump flow, Pi, Pd and Km. Results show that the proposed K-slump test allow to assess both workability and static stability of fresh SCC mixtures.