• 제목/요약/키워드: Abnormal value

검색결과 610건 처리시간 0.033초

Incidental Abnormal FDG Uptake in the Prostate on 18-fluoro-2-Deoxyglucose Positron Emission Tomography-Computed Tomography Scans

  • Kang, Pil Moon;Seo, Won Ik;Lee, Sun Seong;Bae, Sang Kyun;Kwak, Ho Sup;Min, Kweonsik;Kim, Wansuk;Kang, Dong Il
    • Asian Pacific Journal of Cancer Prevention
    • /
    • 제15권20호
    • /
    • pp.8699-8703
    • /
    • 2014
  • 18-fluoro-2-deoxyglucose positron emission tomography-computed tomography ($^{18}F$-FDG PET/CT) scans are commonly used for the staging and restaging of various malignancies, such as head and neck, breast, colorectal and gynecological cancers. However, the value of FDG PET/CT for detecting prostate cancer is unknown. The aim of this study was to evaluate the clinical value of incidental prostate $^{18}F$-FDG uptake on PET/CT scans. We reviewed $^{18}F$-FDG PET/CT scan reports from September 2009 to September 2013, and selected cases that reported focal/diffuse FDG uptake in the prostate. We analyzed the correlation between $^{18}F$-FDG PET/CT scan findings and data collected during evaluations such as serum prostate-specific antigen (PSA) levels, digital rectal examination (DRE), transrectal ultrasound (TRUS), and/or biopsy to confirm prostate cancer. Of a total of 18,393 cases, 106 (0.6%) exhibited abnormal hypermetabolism in the prostate. Additional evaluations were performed in 66 patients. Serum PSA levels were not significantly correlated with maximum standardized uptake values (SUVmax) in all patients (rho 0.483, p=0.132). Prostate biopsies were performed in 15 patients, and prostate cancer was confirmed in 11. The median serum PSA level was 4.8 (0.55-7.06) ng/mL and 127.4 (1.06-495) ng/mL in the benign and prostate cancer groups, respectively. The median SUVmax was higher in the prostate cancer group (mean 10.1, range 3.8-24.5) than in the benign group (mean 4.3, range 3.1-8.8), but the difference was not statistically significant (p=0.078). There was no significant correlation between SUVmax and serum PSA, prostatic volume, or Gleason score. $^{18}F$-FDG PET/CT scans did not reliably differentiate malignant or benign from abnormal uptake lesions in the prostate, and routine prostate biopsy was not usually recommended in patients with abnormal FDG uptake. Nevertheless, patients with incidental prostate uptake on $^{18}F$-FDG PET/CT scans should not be ignored and should be undergo further clinical evaluations, such as PSA and DRE.

난치성 측두엽간질의 발작간 뇌혈류 SPECT, MRI와 수술성과 비교 (Interictal rCBF SPECT, MRI and Surgical Outcome of Intractable Temporal Lobe Epilepsy)

  • 전석길;주양구;이상도;손은익;이영환
    • 대한핵의학회지
    • /
    • 제28권3호
    • /
    • pp.307-312
    • /
    • 1994
  • Interictal single photon emission computed tomography of regional cerebral blood flow (rCBF SPECT) in 18 intractable temporal lobe epilepsy patients(8 male and 10 female patients: average 23.5 years old) were compared with 2.0 T magnetic resonance imaging (MRI). And surgical outcome was analysed with the findings, symptom duration and lateralization of temporal lobe. Preoperatively rCBF SPECT was done in all 18 patients with intravenous injection of 740 MBq 99mTc-HMPAO. MRI was also done preoperatively in 13 patients. Surgical outcome was classified by Engel's outcome classification(four-part classification recommended at the first Palm Desert conference). rCBF SPECT detected correctly lateralising abnormality of temporal lobe hypoperfusion in 13/18(72.2%), contralateral temporal lobe hypoperfusion in 2/18(11.1%) and showed no def-inite abnormality in 3/18(16.7%). The positive predictive value of unilateral temporal lobe hypoperfusion was 87%. MRI detected correct localising abnormality in 8/13(61.5%), such as hippocampal atrophy(7/13), asymmetric temporal horn(6/13), anterior temporal lobe atrophy(1/13), increased signal intensity from hippocampus(1/13) and calcific density(1/13), and no abnormal finding was noted in 5/13(38.5%). There was no false positive findings and the positive predictive value of MRI was 100%. Only 2 cases showed same lateralization findings in rCBF SPECT and MRI. There was no significant correlation between symptom duration and no abnormal findings on SPECT or MRI. Surgical outcome showed class I in 15/18(83.3%), and class II in 2/18(11.1%). One case of no abnormal finding in both SPECT and MRI showed class III surgical outcome. No class IV surgical outcome was noted. Surgical outcome, lateralization of epileptic focus in temporal lobe and abnormal findings in rCBR SPECT or MRI were not significantly correlated.

  • PDF

가속도 값 변화에 따른 HH 스마트센서의 센싱능력 평가 (Estimation of the Sensing Ability of HH Smart Sensor According to Acceleration Value Changing)

  • 황성연;홍동표;박준홍
    • 대한기계학회:학술대회논문집
    • /
    • 대한기계학회 2001년도 추계학술대회논문집A
    • /
    • pp.527-532
    • /
    • 2001
  • In this paper, we will propose the new method that estimates the sensing ability of HH smart sensor. We have developed a new signal processing method that can distinguish among different materials relatively. The HH smart sensor was developed for recognition of materials. We made the HH smart sensor in our experiment. Then, we estimated the ability to recognize objects according to acceleration value. We estimated the sensing ability of HH smart sensor with the $R_{SAI}$ method. Experiments and analysis were executed to estimate the ability to recognize objects according to acceleration value changing. Dynamic characteristics of HH smart sensor were evaluated relatively through a new $R_{SAI}$ method that uses the power spectrum density. Applications of this method are for finding abnormal conditions of objects (auto-manufacturing), feeling of objects (medical product), robotics, safety diagnosis of structure, etc.

  • PDF

가속도 값 변화에 따른 지능센서(HH)의 센싱능력 평가 (Estimation of the Sensing Ability of HH Smart Sensor According to Acceleration Value Changing)

  • 황성연;홍동표;김홍건
    • 한국공작기계학회논문집
    • /
    • 제13권1호
    • /
    • pp.22-27
    • /
    • 2004
  • A new method that estimates the sensing ability of HH smart sensor is proposed. The new signal processing method have been developed that can distinguish among different materials relatively. The HH smart sensor was developed far recognition of materials. The HH smart sensor was made for experiment. Then, it was estimated the ability to recognize objects according to acceleration value. The sensing ability of HH smart sensor has been estimated with the $R_{SAI}$ method. Experiments and analysis were executed to estimate the ability to recognize objects according to acceleration value changing. Dynamic characteristics of HH smart sensor were evaluated relatively through a new $R_{SAI}$ method that uses the power spectrum density. Applications of this method are for finding abnormal conditions of objects (auto-manufacturing), feeling of objects (medical product), robotics, safety diagnosis of structure, etc.

Mobile Ad - hoc Network에서 CP - SVM을 이용한 침입탐지 (Intrusion Detection Algorithm in Mobile Ad-hoc Network using CP-SVM)

  • 양환석
    • 디지털산업정보학회논문지
    • /
    • 제8권2호
    • /
    • pp.41-47
    • /
    • 2012
  • MANET has vulnerable structure on security owing to structural characteristics as follows. MANET consisted of moving nodes is that every nodes have to perform function of router. Every node has to provide reliable routing service in cooperation each other. These properties are caused by expose to various attacks. But, it is difficult that position of environment intrusion detection system is established, information is collected, and particularly attack is detected because of moving of nodes in MANET environment. It is not easy that important profile is constructed also. In this paper, conformal predictor - support vector machine(CP-SVM) based intrusion detection technique was proposed in order to do more accurate and efficient intrusion detection. In this study, IDS-agents calculate p value from collected packet and transmit to cluster head, and then other all cluster head have same value and detect abnormal behavior using the value. Cluster form of hierarchical structure was used to reduce consumption of nodes also. Effectiveness of proposed method was confirmed through experiment.

Investigating the Impact of IT Security Investments on Competitor's Market Value: Evidence from Korea Stock Market

  • Young Jin Kwon;Sang-Yong Tom Lee
    • Asia pacific journal of information systems
    • /
    • 제30권2호
    • /
    • pp.328-352
    • /
    • 2020
  • If a firm announces an investment in IT security, how the market value of its competitors reacts to the announcement? We try to shed light on this question through an event study design. To test the relationship, we collected 143 announcements on cybersecurity investment and measured the subsequent impact on 533 competitors' abnormal returns, spanning from 2000 to 2019. Our estimation results present that, on average, the announcements have no observable impact on the market value of announcing firms and competitors as well, which is consistent with findings of a prior study. Interestingly, however, the impact becomes evident when we classify our samples by industries (Finance vs. non-Finance or ICT vs. non-ICT) and firm size (Big vs. Small). We interpret our empirical findings through the lenses of contagion effect and competition effect between announcing firms and their competitors. Key finding of our study is that, for financial service firms, the effect resulting from the announcement on cybersecurity investment transfers to competitors in the same direction (i.e., contagion effect).

Change of Blood Cells' Number from Capillaries and Venous Blood of 20's Healthy Adults

  • Seon, Ji-Yeong;Lee, Jae Sik
    • 대한임상검사과학회지
    • /
    • 제43권4호
    • /
    • pp.156-160
    • /
    • 2011
  • It was confirmed that we got somewhat different results even though we performed same items with same methods from capillaries and venous blood of healthy 72 cases. Items which capillaries blood has higher value than venous blood are the numbers of erythrocyte, lymphocyte, basophil, hematocrit, MCHC and RDW. Total numbers of RBC (p<0.035), lymphocyte and basophil are shown statistically significance. Items which venous blood has higher value than capillary blood are the numbers of platelet (p<0.00) and neutrophil (p<0.01). Fallible items in clinics can be shown the numbers of RBC, platelet, lymphocyte and neutrophil because we got somewhat different results even though we performed same items with same methods from capillaries and venous blood, respectively. It is necessary to choose the clear criteria and normal value depends on clinical specimen as the number of platelets are measured with an abnormal value shown over 40% down. As normal difference according to each item and method is currently acceptable and applicable in clinics, it is considered that a new normal value depends on clinical specimen should be established and is to be useful positively in clinics.

  • PDF

대기업-중소기업의 상생협력 정책이 기업가치에 미치는 영향: 이벤트연구방법론을 기반으로 (Evaluating the Impact of Win-Win Growth Policy Announcements between Large Firms and SMEs on the Market Value of Firms)

  • 백종현;권순범;최병구
    • 지식경영연구
    • /
    • 제13권5호
    • /
    • pp.139-160
    • /
    • 2012
  • Win-win growth between large companies and small and medium enterprises (SMEs) become a critical encomic and social issue in Korea. Korea government has been attempted to establish strong policy to build right win-win relationship between large companies and SMEs. Along with this strong drive from Korea government, a variety of strategies that enhance win-win relationships between large companies and SMEs have been adopted. Win-win growth policy is expected to provide positive impact on sustainable competitive advantage of firms. Therefore, many studies have focused on the win-win growth policy success factors, type of the policy, and the results of the policy. Although there is much literature on the win-win growth policy, the effects of win-win policy on firm value is not well understood. We addressed this issue by exploring how win-win growth policy influences a firm's market value using event study methodology. We evaluated the cumulative abnormal returns for win-win growth policy announced by Korean large firms from 2004 to 2012. The results of this study insisted that the announcements of win-win growth policy show negative impact on firm's market value, which is not consistent with previous studies. The findings of this study offer insights that may help government policy makers and managers to revise their policy for better outcomes of their win-win growth policy.

  • PDF

ERP 도입의 공시가 기업의 시장 가치에 미치는 영향 (The Impact of ERP Implementation the Announcement on the Market Value of the Firm)

  • 방종욱;김준석;이문봉;김성환
    • Asia pacific journal of information systems
    • /
    • 제12권1호
    • /
    • pp.87-101
    • /
    • 2002
  • In the past few years, many Korean companies have implemented various ERP systems. Despite the enormous efforts and costs, however, there have been doubts about the effectiveness of ERP implementation. The purpose of this study is to identify whether the announcement of ERP implementation affects the market value of the firm. To achieve the research objective, event-study methodology was used assessing the cumulative abnormal returns(CARs) for 33 firms' announcements of ERP investments. Findings of the study are summarized as follows: First, the announcements of ERP implementation have no effect on the firm value though the sign is negative. Second, there is marginally significant difference in the market value of the firm between the first mover of ERP implementation and its followers. In order to figure out any possible reasons of such unexpected results, several investors and fund managers of major investment firms were interviewed. They reached the two agreements that ERP hardly increases the firm value. One was mainly due to the misfit between the foreign business processes built in the ERP systems and Korean firms' traditional business processes. The other was the possibility of financial deterioration caused by substantial costs for ERP implementation.

치과기공사의 호흡기 증상과 폐환기능 검사와의 관계 (Relationship between Pulmonary Function and Symptoms in Dental technicians)

  • 이규선
    • 대한치과기공학회지
    • /
    • 제15권1호
    • /
    • pp.73-87
    • /
    • 1993
  • This study was performed to determine respiratory manifestations of 105 male and 16 female dental technicians who were resident in seoul. The prevalence of respiratory symptoms was 19% on cough, 40% on sputum, 33% on coryza, and 36% on dyspnea without past cardiopulmonary disease. The number of subjects who was abnormal ventilatory function among % predicted value for FVC(<80%), FEV1(<80%) and $FEV_1$/FVC(<75%) was 18(22%). Indices FVC and $FEV_1$ among smokers were 3 to 6% lower than that of nonsmokers.

  • PDF