• Korean Journal of Ecology and Environment
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• v.53 no.1
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• pp.46-54
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• 2020

Artificial and natural changes such as weir construction and climate change often cause abnormal blooming of organism. Therefore, variations in species community of organisms have been actively investigated to identify influential environmental changes on the fresh water ecosystem. In this study, we investigated Chironomidae community and environmental factors at 5 representative weirs (Ipo, IP; Sejong, SJ; Juksan, JS; Gangjeong-goryung, GG; and Dalsung weir) in 4 Korean major rivers to figure out relationship between Chironomidae community and environmental factors. Environmental factors indicating organic matter (total organic carbon, TOC and Chlorophyll-a, Chl-a) showed lower concentration in IP and SJ compared with other sites(JS, GG and DS). 3 sub-family 18 genus 25 species of Chironomidae community were found in this study. Among them, Chironominae was dominant in JS (Tanytarsus sp.1), GG (Polypedilum scalaenum) and DS (Polypedilum scalaenum), while different sub-family were dominant in IP (Orthcladinae, Tokunagayusurika akamushi) and SJ (Tanypodinae, Tanypus punctipennis). Moreover, based on the dominant species of Chironomidae community and environmental factors, the cluster analysis classified our study sites into 3 groups. These results imply that the diet resource is the most important factor for dominance of Chironomidae in Korean rivers. We also suggest that further study on the identification of diet resources for each Chironomidae specie is required for better understating of distribution in species community of Chironomidae at various ecosystems.

• The Korean Journal of Nuclear Medicine
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• v.30 no.4
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• pp.502-506
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• 1996

Tc-99m myocardial perfusion agents such as Tc-99m sestamibi or Tc-99m tetrofosmin has advantages over T1-201 for myocardial perfusion scan fuck as low attenuation and easy availability. However, Tc-99m agents do not redistribute so they need to be given T times, namely after stress and at rest. To evaluate whether rest image is needed in patients showing normal stress image, 43 patients who underwent both myocardial perfusion scan and coronary angiography and showed normal stress images were evaluated. Findings of rest images of them were evaluated whether they change the diagnosis or treatment plans. Among 43 patients who showed normal stress myocardial perfusion imaging, 31 (72.1%) showed no additional informations. However, among 5 patients with vasospastic angina 4 (80%) showed abnormal rest images in spite of normal stress images. So, when vasospastic angina is suspected clinically, rest image could be helpful in identifying patients with coronary vasospasm. In conclusion, rest myocardial perfusion images were not helpful in 72.1 % of patients with angina when stress images were normal. In only exception was those with vasospastic angina.

• The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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• v.4 no.2
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• pp.127-135
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• 1999

Grain-size distribution and accumulation rate of surface sediments on the tidal flats in Hampyong Bay, southwestern coast of Korea, were investigated in a sequential interval of 2 months for the period of 27 months (1994. 10~1996. 12). Seasonal variation of grain-size distribution is prevalent on the Shimock tidal flat in the southern side of the innerbay, rather than the Anarc tidal flat in the northern side around the baymouth. This variation, in particular, more distinctive in the areas around the both high and low tide water levels. The Shimock tidal flat shows typical seasonal variation of sedimentary processes, expected under monsoonal climate. Deposition of tine-grained sediments in summer dominates over erosion in winter, resulting in an annual accumulation rate of 3.7 mm/yr. In contrast, sedimentary processes on the Anarc tidal flat is abnormal that have experienced slight deposition of fine-grained sediments in the winter and severe erosion in the summer time, showing a negative annual accumulation rate of -49.6 mm/yr. Erosional processes in this area is interpreted due mainly to change of strength and direction of tidal currents, caused by the artificial construction of dyke for reclamation in the mid-tidal flat. As a result, It is immoderate to conclude whether sedimentary processes of Hampyong Bay is erosional or depositional at current situation. Further studies on sedimentary budget at the entrance to the bay are needed.

• Journal of The Korean Society of Inherited Metabolic disease
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• v.14 no.2
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• pp.123-134
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• 2014

Recent advances in the diagnosis and treatment of inborn errors of metabolism (IEM) have improved substantially the prognosis of many of these diseases, if diagnosed early enough before irreversible damage occurs. Diseases of inborn errors of metabolism are so diverse over several hundred disease up to now and may be several thousand in near future, and these diversities of IEMs make clinicians embarassed. The signs of neurological dysfunctions of many IEMs manifesting in the neonatal period is very nonspecific, such as poor feeding, poor sucking, apnea or tachypnea, vomiting, hypertonia, hypotonia, seizure, letharginess, consciousness change and coma. But after neonatal period, the signs of neurological deficits become specific and localized. The results of routine basal laboratory tests such as metabolic acidosis, hyperammonemia, lactic acidemia, ketonemia or hyperuricemia can give very important clinical clues for the diagnosis of IEMs. Even no abnormal findings on routine laboratory test could be very important clue for NKH, sulfite oxidase deficiency and peroxisomal disorders. These various clinical manifestations of these diverse diseases can be categorized and summarized. This makes it essential that the practicing clinicians be familiar with the clinical presentations and symptomatic and systematic approaches of these disorders. Characteristic clinical presentations, methods of symptomatic and systematic approach and typing of various disorders is discussed in this review.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.4
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• pp.2876-2882
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• 2015

The object of this study is to identify changes in air pollution in the maximum ground level concentration and the surrounding area when air pollution control facilities are improved in the thermal power plants. The effects of improved facilities are analyzed by comparing air quality after applying improved air pollution control facilities. For prediction of air quality, the change of wind field can be represented with movement of Puff and CALPUFF Model, air pollution diffusion models which can implement abnormal conditions. Major air pollutants of thermal power plants such as $SO_2$, $NO_2$, and $PM_{10}$ are selected as prediction items. That results show that improvement of air pollution control facilities is significantly effective in reduction of air pollution of $SO_2$ and $NO_2$ in the maximum ground level concentration and areas around of thermal power plants. In the case of $PM_{10}$, it is found that the effect of reduction in pollution is high in the maximum ground level concentration, but the effect of reduction in air pollution is somewhat low in the area around of the thermal power plant.

• Journal of Food Hygiene and Safety
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• v.33 no.3
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• pp.207-213
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• 2018

This study aimed to evaluate the genotoxicity of Litsea japonica fruit-hexane extract (LJF-HE). In order to examine the genotoxicity, we carried out bacterial reverse mutation assay, chromosome aberration assay, and a micronucleus induction (MN) test according to the OECD and the Korea Ministry of Food and Drug Safety (MFDS) toxicity test guidelines. In the bacterial reverse mutation assay, no significant increase in revertant colonies, nor bacterial toxicity, was observed in the LJF-HE treatment group, regardless of the absence or presence of metabolic activation by the S9 mixture. However, in the positive control group, revertant colony counts were shown to be more than twice that of the negative control group. The chromosome aberration test showed that the repetition rate of abnormal chromosome aberration was less than 5%, regardless of the treatment time, and with or without the S9 mixture. No significant change was observed when (p < 0.05) compared with the negative control group. The micronucleated polychromatic erythrocytes (MNPCE) repetition rate of the polychromatic erythrocytes (PCE) showed no significant changes when compared with the negative control group (p < 0.05). The PCE portion of total erythrocytes also showed no significant changes (p < 0.05). These results showed that LJF-HE had no significant genotoxic effects.

• Journal of Life Science
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• v.27 no.11
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• pp.1376-1380
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• 2017

This study examined how the daily administration of dried CP roots affects body-weight gains of mice. An aqueous CP extract (1 g/kg of CP-W) was orally administered to mice on a daily basis for ten weeks, and the mice's body weights and food intakes were measured throughout the period. At the end of the ten-week treatment, murine blood samples were taken and hematological and serum biochemical parameters were examined. The mice's intra-abdominal organs were weighed at necropsy. The treatment of CP-W significantly suppressed the mice's body-weight gain by about 10%. There were no changes to the food intakes of and no observable abnormal clinical signs in any of the animals throughout the experimental period. There were no significant differences between the control and CP-W mice in regards to the hematological and serum biochemical parameters and the organ weights at necropsy. The results demonstrated that the daily administration of CP-W for ten weeks suppresses body-weight gain in mice and does not change mice's food intake or cause any noticeable toxic effects.

• Proceedings of the Microbiological Society of Korea Conference
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• 2000.05a
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• pp.23-36
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• 2000

Japanese encephalitis virus (JEV) is the causative agent of a mosquito-borne encephalitis and is transmitted to human via persistently infected mosquito vectors. Although the virus is known to cause only acute infection, there were reports that showed neurological sequelae, latent infection in peripheral mononuclear cells, and recurrence of the disease after acute encephalitis. Innate resistance of certain cell lines, abnormal SN1 expression of the virus, and anti-apoptotic effect of cullular bcl-2 have been suggested as probable causes of JEV persistence even in the absence of defective interfering (DI) particles. Although possible involvement of DI particles in JEV persistence was suggested, neither has a direct evidence for DI presence nor its molecular characterization been made. Two questions asked in this study are whether the DI virus plays any role in JEV persistent infection if it is associated with and what type of change(s) can be made in persistently infected cells to avoid apoptosis even with the continuous virus replication, DI-free standard stock of JEV was infected in BHK-21, Vero, and SW13 cells and serial high multiplicity passages were performed in order to generate DI particles. There different-sized DI RNA species which were defective in both structural and nonstructural protein coding genes. Rescued ORFs of the DI genome maintained in-frame and the presence of replicative intermediate or replicative form RNA of the DI particles confirmed their replication competence. On the other hand, several clones with JEV persistent infection were established from the cells survived acute infections during the passages. Timing of the DI virus generation during the passages seemed coincide to the appearance of persistently infected cells. The DI RNAs were identified in most of persistently infected cells and were observed throughout the cell maintenance. One of the cloned cell line maintained the viral persistence without DI RNA coreplication. The cells with viral persistence released the reduced but continuous infectious JEV particle for up to 9 months and were refractory to homologous virus superinfection but not to heterologous challenges. Unlike the cells with acute infection these cells were devoid of characteristic DNA fragmentation and JEV-induced apoptosis with or without homologous superinfection. Therefore, the DI RNA generated during JEV undiluted serial passage on mammalian cells was shown to be biologically active and it seemed to be responsible, at least in part, for the establishment and maintenance of the JEV persistence in mammalian cells. Viral persistence without DI RNA coreplication, as in one of the cell clones, supports that JEV persistent infection could be maintained with or without the presence of DI particles. In addition, the fact that the cells with JEV persistence were resistant against homologous virus superinfection, but not against heterologous one, suggests that different viruses have their own and independent pathway for cytopathogenesis even if viral cytopathic effect could be converged to an apoptosis after all.

• Journal of the Korean Association of Geographic Information Studies
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• v.10 no.2
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• pp.47-57
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• 2007

Real-time oceanographic information system was developed using platforms of aquaculture farms to examine causes of mass mortality of hatchery fishes, and to reduce the damage of mass mortality which has been occurred frequently off coast by abnormal change of ocean conditions. The system had the advantages of direct data distribution to fishermen at the farm and instant maintenance of equipments due to easy access to the farms and residents at the farms in comparison with offshore mooring buoy system. To avoid discontinued measurement of the system, repairs caused by malfunction of equipments, bimonthly preventive maintenances and daily monitoring of measured data were systematized. Confidence intervals calculated by a statistical method using accumulated data were applied to data management. Such activities could minimize discontinuance of measurement and keep information more trustful. In addition, the system has various ways of data distribution. Through homepage and e-mail in the internet, information was provided to public. Display units which were connected to equipments at the farm gave the measured data directly to fishermen, which guided them to run their farm scientifically. Finally large display unit was installed at a fish market and showed the measured data at the nearest station with tide and weather information. Proper region for aquaculture and wintering region were studied using temperature data obtained by the system in 2006. The system will contribute to reduce economic damage of coastal fishery and to understand coastal marine environment.

• Journal of Korea Water Resources Association
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• v.53 no.11
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• pp.1015-1024
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• 2020

Recently, water pollution accidents have continued to occur in pipelines such as red water Incheon and Seoul. In order to recognize this water quality problem, it is necessary to install a water quality sensor in an appropriate location and measure it in advance to detect or block the water supply to the water faucet of the shelter. However, there are limitations, such as maintenance costs, to installing multiple water meters in all pipelines. Therefore, this study proposed a methodology for determining and prioritizing the installation location of flow-based water quality sensor for the recognition of water quality problems in pipelines. We applied the proposed procedure to the pipe break scenario. The results of the determination of the location of the water quality sensor were presented by applying it to the pipe network that actually operates the emergency pipe in Korea. The result of the decision showed that in the event of abnormal situation caused by the destruction of individual pipes, the flow rate of the pipes around the aqueduct and the tank may change rapidly, resulting in water quality accidents caused by turbidity. In the future, it is expected that the water quality monitoring point selection method, such as establishing an external pipe operation plan for pipe cleaning, will utilize the procedure for determining the location of the water quality sensor according to the velocity.